• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2003년도 The Fifth Asian Computational Fluid Dynamics Conference
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• pp.19-20
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• 2003

Brownian-dynamics simulation on highly charged colloidal suspensions is performed by employing Tokuyama effective force recently proposed. The radial distribution function suggests that there exist three novel phases, a gas phase, a liquid droplet phase, and a face-centered cubic (FCC) crystal droplet phase, depending on the minimum values of that potential. The dynamics of droplet growth is also investigated both in liquid droplet phase and in crystal droplet phase. Thus, different types of characteristic growth stages are found.

• Journal of Magnetics
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• 제10권3호
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• pp.108-112
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• 2005

GaAs nanowires were grown on GaAs (111)B substrates in a gas source molecular beam epitaxy system, using self-assembled Au particles with diameters between 25 and 200 nm as the catalytic agents. The growth rate and structure of the nanowires were investigated for substrate temperatures between 500 and $600^{\circ}C$ to study the mass transport mechanisms that drive the growth of these crystals. The possibilities for fabrication of novel magnetic nanostructures by suitable choice of growth conditions are discussed.

• 만화애니메이션 연구
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• 통권43호
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• pp.231-254
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• 2016

그래픽 노블은 시각적 표현 부분 및 서사적 가치의 측면에서 대개 일반 만화와 다르다고 인지된다. 그러나 이 모호한 기준 때문에 각 작품을 통해 그래픽 노블의 잠재성을 제고해야 할 필요성이 제기된다. 이에 본 연구에서는 비교적 최근에 그래픽 노블로 널리 인정받은 작품인 크레이그 톰슨의 "하비비"를 대상으로 표현양식과 서사 양쪽 면에서 그 특성을 분석하고자 한다. 미국 작가가 아랍권의 여성을 그려내기 위해 의도적으로 선택한 표현양식이 어떻게 서사와 연계되는지 분석함으로써, 그래픽 노블이 가질 수 있는 서사적 전략을 살펴볼 수 있을 것으로 보인다. 이에 "하비비"에 나타난 아랍 문자의 이미지화를 중심으로 새로운 표현양식을 연구하고, 게일 루빈의 여성 거래 이론으로 "하비비"에 투영된 여성 성장서사를 살펴, 이것이 어떻게 그래픽 노블의 표현양식과 결합하였는지 연구하였다. 본 연구는 독자적 서사 형식을 지닌 만화 매체로서 그래픽 노블이 가진 표현양식의 스펙트럼을 넓히고, 서사의 잠재성을 연구하는데 도움이 될 것이다.

• Genomics & Informatics
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• 제19권1호
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• pp.6.1-6.10
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• 2021

Vascular endothelial growth factor (VEGF) is expressed at elevated levels by most cancer cells, which can stimulate vascular endothelial cell growth, survival, proliferation as well as trigger angiogenesis modulated by VEGF and VEGFR (a tyrosine kinase receptor) signaling. The angiogenic effects of the VEGF family are thought to be primarily mediated through the interaction of VEGF with VEGFR-2. Targeting this signaling molecule and its receptor is a novel approach for blocking angiogenesis. In recent years virtual high throughput screening has emerged as a widely accepted powerful technique in the identification of novel and diverse leads. The high resolution X-ray structure of VEGF has paved the way to introduce new small molecular inhibitors by structure-based virtual screening. In this study using different alkaloid molecules as potential novel inhibitors of VEGF, we proposed three alkaloid candidates for inhibiting VEGF and VEGFR mediated angiogenesis. As these three alkaloid compounds exhibited high scoring functions, which also highlights their high binding ability, it is evident that these alkaloids can be taken to further drug development pipelines for use as novel lead compounds to design new and effective drugs against cancer.

• 비교문화연구
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• 제47권
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• pp.1-26
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• 2017

본 논문은 1990년대 이후 발표된 여화(余華)의 "재세우중호함(在細雨中呼喊)"(1993), 소동(蘇童)의 "성북지대(城北地帶)"(1994), 왕강(王剛)의 "영격역사(英格力士)"(2004)에 나타난 가족결핍과 그 서사적 대응방식을 살펴보는 것을 목적으로 삼는다. 소설에 공통적으로 등장하는 소재인 결핍된 가족은 존재의 부재를 뜻하기도 하지만 그 기능과 역할의 부재를 의미하기도 한다. 결핍을 야기하는 원인은 작품마다 서로 다르며 대응 양상 또한 차이를 보인다. 중국의 성장 서사는 오랜 시간 동안 전통의 유제와 여러 가지 정치적 압박 속에서 성장과정에서 일어나는 부모와의 갈등, 성장자 자신의 내면의 고통들을 집단의 경험 속에 매몰시켰다. 성장의 기억을 개인에게 돌려주기 시작했던 1980년대의 선취에 힘입어 1990년대 성장 서사는 지나간 연대의 강박과 피로에서 벗어난 작가들의 다양한 시도 속에서 더욱 풍부한 함의를 지니고 있다. "가랑비 속의 외침"은 친부모와 양부모에게 의도치 않은 '버려짐'을 당한 주인공의 심리적 고아의식을 보여주었고, "성북지대"는 부재된 가족에게 염증을 느끼고 또래 집단 속에서 위안을 받는 아이들의 서로 다른 성장의 이야기를 들려준다. "오, 나의 잉글리쉬 보이"는 동일시의 대상을 등장시킨다는 점에서 중국 성장소설의 주류적 서사와 구분된다. 개인의 성장은 그를 통해 진일보하고 결국 성장자 자신의 정체성을 확립하게 된다는 점에서 이 소설은 성장소설의 모범사례로 여겨진다.

• Mycobiology
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• 제49권5호
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• pp.521-526
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• 2021

Three isolates belonging to the ascomycetous genus Zygotorulaspora were obtained from the fruits of Cornus officinalis and Smilax china, and flowers of Dendranthema zawadskii var. latilobum in Gongju-si, Korea. Phylogenetic Analyses of the LSU D1/D2 domain and ITS region sequences supported the recognition of two new species: Zygotorulaspora cornina sp. nov. (type strain NIBRFGC000500475 = KACC93346P^PP) and Zygotorulaspora smilacis sp. nov. (type strain NIBRFGC000500476 = KACC93347P^PP). The two novel species revealed no growth on D-Galactose, unlike the other six species in the genus Zygotorulaspora. They are distinguished from each other by their phylogenetic differences and phenotypic characteristics such as assimilation of xylitol, 5-keto-D-gluconate, and ethanol. All species in the genus Zygotorulaspora including the two novel species have phenotypic traits of genus Zygotorulaspora: asci are persistent, sucrose and raffinose are assimilated, and m-inositol is not required for growth, and they are mainly associated with plants.

• Journal of Microbiology and Biotechnology
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• 제18권4호
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• pp.611-615
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• 2008

Novel groups of uncultivable anaerobic thermophiles were isolated from compost by enrichment cultivation in medium with a cell-free extract of Geobacillus toebii. The cell-free extract of G. toebii provided the medium with growth-supporting factors (GSF) needed to cultivate the previously uncultured microorganisms. Twenty-nine GSF-requiring candidates were successfully cultivated, and 16 isolated novel bacterial strains were classified into three different groups of uncultivable bacteria. The similarity among these 16 isolates and a phylogenetic analysis using 16S rRNA gene sequences revealed that these GSF-requiring strains represented novel groups within the family Clostridiaceae.

• BMB Reports
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• 제42권12호
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• pp.769-775
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• 2009

Periplasmic glucans (PGs) are general constituents in the periplasmic space of Proteobacteria. PGs from bacterial strains are found in larger amounts during growth on medium with low osmolarity and thus are often been specified as osmoregulated periplasmic glucans (OPGs). Furthermore, they appear to play crucial roles in pathogenesis and symbiosis. PGs have been classified into four families based on the structural features of their backbones, and they can be modified by a variety of non-sugar substituents. It has also recently been confirmed that novel PGs with various degrees of polymerization (DPs) and/or different substituents are produced under different growth conditions among Proteobacteria. In addition to their biological functions as regulators of low osmolarity, PGs have a variety of physico-chemical properties due to their inherent three-dimensional structures, hydrogen-bonding and complex-forming abilities. Thus, much attention has recently been focused on their physico-chemical applications. In this review, we provide an updated classification of PGs, as well as a description of the occurrences of novel PGs with substituents under various bacterial growth environments, the genes involved in PG biosynthesis and the various physico-chemical properties of PGs.

• 한국전문물리치료학회지
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• 제19권3호
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• pp.72-80
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• 2012

The purpose of the present study was to investigate the effects of familiar exercise and novel exercise on motor function after intracerebral hemorrhage (ICH) in rats. The rats were subjected to a unilateral striatal ICH via collagenase infusion. The rats were randomly divided into the following three groups: the CON (control group; rested one week post-ICH), the FE (familiar exercise group; familiar exercise was performed two weeks after one-week post-ICH period), and NE (novel exercise group; novel exercise was performed two weeks after one-week post-ICH period). We measured neurological behavior using a ladder rung walking test and a beam walking test; we measured the level of nerve growth factor (NGF) using immunohistochemistry and western blot analysis. We performed a one-way ANOVA test to analyze the scores obtained from the neurological behavior tests and the differences of NGF protein levels among the three groups. In the present study, the FE group and the NE group showed significant improvement during the neurological behavior tests and in their expression of NGF protein level, as compared to the CON group. Especially, NE group more increase than FE group in neurological behavior tests, the expression of NGF on motor cortex. In conclusion, these results suggest that, after ICH, familiar exercise and novel exercise enhance motor function and, novel exercise is more effective than familiar exercise.

• International Journal of Advanced Culture Technology
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• 제11권4호
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• pp.141-153
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• 2023

In the global context, particularly in Christian nations, Christmas is considered a culturally and ethically significant time. In this study, we examine Charles Dickens' novel, "A Christmas Carol," and the celebration of Christmas in Korea. We explore the values of Christmas in Korea derived from the significance and importance of this novel. These values include repentance, empathy, compassion, and the importance of humanity. Korean Christmas is regarded as a time for practicing these values, bearing a message akin to the transformation of characters like Scrooge. Furthermore, "A Christmas Carol" conveys a message of improvement and change over time, emphasizing change and growth in Korean Christmas. People reflect on their past, correct their mistakes, nurture hope for the future, and experience personal growth and transformation. Additionally, the novel raises awareness of social injustice and inequality, offering alternatives. In Korean society, Christmas encourages the willingness to care for and help others, facilitating discussions and understanding of societal issues. For these reasons, "A Christmas Carol" is considered a culturally and ethically significant time in Korean Christmas, and the two are intertwined in various aspects. This study explores the interaction between cultural change and ethical teachings by 'A Christmas Carol' and investigates the impact of this work on Christmas culture and social change. It serves as the basis for emphasizing moral principles and humanity during the Christmas season, and this research provides suggestions for future research directions, aiming to deepen the understanding of Dickens' work and the importance of "A Christmas Carol." Through these efforts, it is expected that valuable insights into the connection between Christmas culture and moral messages will be gained. In this study, we will delve into the enduring appeal and cultural significance of "A Christmas Carol," discussing how this novel has evolved into a beloved holiday tradition and a true symbol of Christmas. We will also examine the adaptation of this novel into various media and its influence on holiday season celebrations. Insights into the impact of this novel on Korean society and its continued significance in modern times will be provided, suggesting a direction for a healthier and more desirable path for Korean society.