• 제목/요약/키워드: growth after recovery

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Human adipose-derived mesenchymal stem cell spheroids improve recovery in a mouse model of elastase-induced emphysema

  • Cho, Ryeon Jin;Kim, You-Sun;Kim, Ji-Young;Oh, Yeon-Mok
    • BMB Reports
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    • v.50 no.2
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    • pp.79-84
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    • 2017
  • Emphysema, a pathologic component of the chronic obstructive pulmonary disease, causes irreversible destruction of lung. Many researchers have reported that mesenchymal stem cells can regenerate lung tissue after emphysema. We evaluated if spheroid human adipose-derived mesenchymal stem cells (ASCs) showed greater regenerative effects than dissociated ASCs in mice with elastase-induced emphysema. ASCs were administered via an intrapleural route. Mice injected with spheroid ASCs showed improved regeneration of lung tissues, increased expression of growth factors such as fibroblast growth factor-2 (FGF2) and hepatocyte growth factor (HGF), and a reduction in proteases with an induction of protease inhibitors when compared with mice injected with dissociated ASCs. Our findings indicate that spheroid ASCs show better regeneration of lung tissues than dissociated ACSs in mice with elastase-induced emphysema.

Interactive Effects of Ozone and Light Intensity on Platanus occidentalis L. Seedlings

  • Kim, Du-Hyun;Han, Sim-Hee;Lee, Kab-Yeon;Kim, Pan-Gi
    • Journal of Korean Society of Forest Science
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    • v.97 no.5
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    • pp.508-515
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    • 2008
  • Sycamore (Platanus occidentalis L.) seedlings were grown under low light intensity and ozone treatments to investigate the role of the light environment in their response to chronic ozone stress. One-year-old seedlings of Platanus occidentalis L. were grown in pots for 3 weeks under low light (OL, $150{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$) and high light (OH, $300{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$) irradiance in combination with 150 ppb of ozone fumigation. After three weeks of ozone and light treatment, seedlings were placed in ozone free clean chamber for 3 weeks for recovery from ozone stress with same light conditions to compare recovery capacity. Ozone fumigation determined an impairment of the photosynthetic process. Reduction of leaf dry weight (14%) and shoo/root ratio (17%) were observed in OH treatment. OL treatment also showed severe reductions in leaf dry weight and shoot/root ratio by 48% and 36% comparing to control, respectively. At the recovery phase, OH-treated plants recovered their biomass, whereas OL-treated plant showed reduction in leaf dry weight (52%) and shoot/root ratio (49%). OH-treated plants reached similar relative growth rate (RGR) comparing to control, whereas OL-treated plants showed lower RGR in stem height. However, there were no significant differences in response to those treatments in stem diameter RGR at the recovery phase. Ozone treatment produced significant reduction of net photosynthesis in both high and low light treatments. Carboxylation efficiency and apparent quantum yield in OL-treated plants showed significant reductions rate to 10% and 45%, respectively. At the recovery stage, ozone exposed seedlings under high light had similar photosynthetic capacity comparing to control plants. Antioxidant enzymes activities such as superoxide dismutase (SOD), ascorbate peroxidase (APX), and glutathione reductase (GR) were increased in ozone fumigated plants only under low light. The present work shows that the physiological changes occur in photosynthesis-related parameters and growth due to ozone and low light stress. Thus, low light seems to enhance the detrimental effects of ozone on growth, photosynthesis, and antioxidant enzyme responses.

Changes of the Yield and Carbohydrate Content during the Regrowth of the Pastuer plants - Especially Ladno clover and Orchardgrass- (재생기간별 목초의 수량 및 탄수화물함량 변화 - Ladino Clover와 Orchardgrass를 중심으로 -)

  • 전우복
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.1 no.1
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    • pp.10-17
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    • 1978
  • The experiment were carried out to determine the rate of regrowth, the changes of carbohydrates contained in the samples right after cutting, plant part for storage of carbohydtates and top-dressing time of ladino clover and orchardgrass. Plants were grown in the simple growth chamber as well as in the fields. The temperature, light intensity and light period were controlled to be 15-20$^{\circ}$, 4,250 Lux, and 15 hours in the simple growth chamber. The results obtained are as follows ; 1. The period of recovery to initial stands after cutting was about 3 weeks in ladino clover and 4-5 weeks in orchard grass in terms of dry matter and carbohydrates. 2. The content of total water-soluble carbohydrates of plant parts was the hightest in stolon of ladino clover and in sheath of orchardgrass, and the lowest in roots of ladino clover and orchardgrass. 3. Cutting resulted in a temporary decrease of total water-soluble carbohydrates in the shoots. Similar trends were observed when the plants were left intact with top-dressing. 4. The top-dressing applied simultalliousely with the cutting was more effective to stimu1ate regrowth than that applied after cutting, however, both of the simultaneous and after cutting application were still better than application prior to cutting.

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Service Failure, Service Recovery Activity and Satisfaction with Online Shopping Channel of Apparel Products (온라인 의류쇼핑에서 서비스 실패 경험 후 쇼핑채널의 회복노력에 따른 채널만족도)

  • Kang, Eun Jung;Lee, Kyu-Hye
    • Journal of Digital Convergence
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    • v.11 no.2
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    • pp.115-125
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    • 2013
  • Unexpected consumer dissatisfaction emerges through rapid growth and expansion of on-line shopping channel. This research focused on the fashion online retail channels' negative aspect caused by service failure which possibly disappointed consumers. We also tried to seek for appropriate service recovery types based on frequently offered recovery types on-line. Data from college students were analyzed. Results indicate that fitting problem, insufficient information, product defect, inventory problem and slow delivery were the main service failure types in apparel e-shopping. Regression analysis identified that among these types, insufficient information, product defect, and slow delivery had significant influence on channel satisfaction after post recovery effort. Results also confirmed significant relationships between channel satisfaction and channel switching. Consumers perceived benefit level causes overall channel satisfaction level to rise while perceived risk leads to lower level of channel satisfaction. Choosing desirable service recovery activities in each service failure situations is necessary in order to raise consumer's channel satisfaction in online apparel shopping.

Brain Plasticity and Stroke Rehabilitation (뇌가소성과 뇌졸중 재활)

  • Kim, Sik-Hyun
    • PNF and Movement
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    • v.6 no.2
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    • pp.39-50
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    • 2008
  • Purpose : This article reviewed the advances in the understanding of the effect of motor rehabilitation and brain plasticity on functional recovery after CNS damage. Methods : This is literature study with Pubmed, Medline and Science journal. Results : The inability of CNS neurons to regenerate is largely associated with nonneuronal aspects of the CNS environment. Especially, this neuronal growth inhibition is mediated by myelin associated glycoprotein, olygodendrocyte-myelin glycoprotein, and NOGO. Enriched environment, motor learning, forced limb use have been utilized in scientific studies to promote functional reorganization and brain plasticity. Especially, enriched environment and motor enrichment may prime the brain to respond more adaptively to injury, in part by expressed neurotrophic factors. Conclusions : These reviews suggest that activity-induced neural plasticity occur in damaged brain areas in order to functional reorganization, where it could contribute to motor recovery, and represent a target for stroke rehabilitation.

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Optimization of Extraction of Fpase from the Fermented Bran of Aspergillus niger in Solid State Fermentation

  • Chandra, M. Subhosh;Reddy, B. Rajasekhar;Choi, Yong-Lark
    • Journal of Applied Biological Chemistry
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    • v.51 no.4
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    • pp.155-159
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    • 2008
  • A local isolate of Aspergillus niger was cultivated under optimal growth conditions on wheat bran in solid state fermentation. Filter paperase from fermented bran was separately extracted with different solvents to test the recovery of the enzyme. Among solvents tested, distilled water served as the best leachate, thus the conditions were further optimized with distilled water. After two washes of fermented bran with distilled water for 1.5 h each under stationary conditions at 1 g wheat bran: 5 mL distilled water, the maximum recovery of 13.5 $Ug^{-1}$ of wheat bran was obtained.

A Study on Characteristics of HRSG Boiler Inner Tube Scale (HRSG 보일러 튜브 내면 스케일의 특성연구)

  • Lee, Seung-Min;MIN, Byung-Yeon;JEONG, Nyeon-Ho
    • Corrosion Science and Technology
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    • v.11 no.3
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    • pp.82-88
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    • 2012
  • The thickness and chemical composition of oxides on heat recovery steam generator tubes of combined cycle power plant were examined in order to evaluate the corrosion of the tubes. Tubes were removed from the plant after actual operations for 21,482, 42,552 and 56,123 hours respectively. Thickness and growth rate of the oxide scale on reheater inner tube (SA213-T22) were very high compared to those other tubes. The oxide scale was about $250{\mu}m$ thick and uniform. The components of the scale were iron oxides. The oxide scale was mixed oxides consisting of magnetite$(Fe_3O_4)$ and hematite$(Fe_2O_3)$. The oxide on inner tube was removed using many kinds of chemicals and it was found that chelating agents were dissolved faster than other chemicals.

A Case of Atypical Bone Growth after Femur Neck Fracture in the Paraplegic Patient with Trochanteric Sore (대전자부 압박궤양을 가지고 있는 하지마비 환자에서 대퇴골 골절부위에 발생한 비정상적 골증식의 치험례)

  • Yang, Jeong Yeol;Cheon, Ji Seon
    • Archives of Plastic Surgery
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    • v.35 no.1
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    • pp.92-95
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    • 2008
  • Purpose: Heterotopic ossification in pressure sore patients is reported to rarely develop, but once it occurs, it frequently causes joint stiffness and mobilization restriction. The aim of this article is to report our experience of atypical bone growing at femur neck fracture site with chronic, extensive pressure sore in patient with paraplegia secondary to spinal injury. Methods: A 28-year-old male patient presented with atypical bone growth at femur neck fracture site with pressure sore. He had undergone atypical growth bone removal and separation of united iliac bone and femur, and then pressure sore was covered by advanced rotation flap. Results: The patient mobilized hip joint and rode in a wheelchair. Complications such as dehiscence, infection, hematoma and flap necrosis did not occur. Conclusion: We experienced successful correction of atypical bone growth removal and recovery of pressure sore. We report our experience of atypical bone growth of fracture site and the related literature was reviewed.

Does the ICT Investment of Firms Create Jobless Growth? (기업의 ICT투자가 '고용 없는 성장'을 이끄는가?)

  • Sim, Jae-yoon;Lee, Jongho;Park, Su-Ho;Jung, Woo-Jin
    • Knowledge Management Research
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    • v.20 no.3
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    • pp.1-16
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    • 2019
  • Jobless Growth, one of the most issue keywords for Korea's economy at this moment, stands for an economic situation where the unemployment rate once edging up at the downturn does not fall sharply even after a business cycle is on the stage of its recovery. A remarkable progress of ICT has intensified the apprehension of technology displacing human labor. A remarkable progress of ICT has intensified the apprehension of technology displacing human labor historically. Nowadays, ICT as the main cause for recent jobless growth in Korea ends up with pointing out. This study is to investigate whether the ICT leads to an economic situation of jobless growth. We served an empirical analysis using firm-level panel data from 2009 to 2013 and estimated the effects of ICT on both firm's employment and productivity. A result suggests not only does the employment increase with the rise of ICT investment, but also the employment becomes a complete mediator in terms of linking ICT and firm's productivity. It turns out to be a groundless fear that the ICT rules out human labor causing jobless growth for Korea's economy according to the result revealed.

Trends of Post-fire Forest Recovery in the South Sikhote-Alin Mountains, Russian Far East

  • Komarova, Tatiana A.;Sibirina, L.A.;Papaik, M.J.;Park, J.H.;Kang, HoSang
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.16 no.3
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    • pp.83-95
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    • 2013
  • To understand natural regeneration and stand development after fire in mixed broadleaved-coniferous forests of Sikhote-Alin Mountains, ten sample plots of $50m{\times}50m$ size were established in 1975 and 1983 at the stands burned by wildfires in 1973 and 1982, respectively. And, the number of naturally regenerated seedlings were monitored in two $50m{\times}4m$ subplots in each plot. The most fire-sensitive conifer species is Abies nephrolepis, while Betula costata is the most fire-sensitive broadleaved tree species. The most fire-resistant species were Q. mongolica, T. taquetii and A. mono. The results of 20 and 30 years after the fire showed that pioneer tree species, e.g. Populus, Salix, and Betula, were regenerated immediately at the early stage of stand development and grew where there is a mono canopy layer with high density. On the other hand, the densities of successors, e.g. Pinus koraiensis, Picea jezoensis, Abies nephrolepis, Acer mono and Tilia taquetii, which were present in the study plots before the fire, increased gradually. Naturally regenerated tree species after forest fire by the growth rate were divided into three groups according to their annual height growth. The seral tree species (Betula costata, Betula platyphylla, Padus maackii, Populus tremula and Sarix caprea) belong to the first group and have the highest growth rate (from 40 to 96 cm per year). The late successional broad-leaved trees (Tilia taquetii, Acer mono and Quercus mongolica) belong to the second group and have intermediate annual height growth (from 3.7 to 13.5 cm per year). The late successional coniferous species (Picea jezoensis, Pinus koraiensis and Abies nephrolepis) form the third group and have the least annual height growth (from 1.4 to 3.5 cm per year).