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Effect of Beni-Koji with Chitosan-Ascorbate on Serum Lipid Profile of Rats Fed a High Fat Diet (Chitosan-Ascorbate 함유 홍국이 고지방 식이 흰쥐의 혈청지질에 미치는 영향)

  • Shin Jin-Gi;Lee Sang-Il;Kwon Jung-Ho;Kim Soon-Dong
    • Journal of the East Asian Society of Dietary Life
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    • v.15 no.5
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    • pp.524-530
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    • 2005
  • Dietary effect of soyfiber beni-koji (SBK) with chitosan-ascorbate (CA) on the level of serum lipids in rats fed a high fat diet was investigated The experimental groups which were divided into high fat diet control group(HC-group), $2\%\;SBK+0.1\%$ CA mixture diet group(CA1-group), $2\%\;SBK+0.15\%$ CA mixture diet group(CA2-group), and $2\%\;SBK+0.2\%$ CA mixture diet group (CA2-group) were fed for 4 weeks. Weight gains in CA2- and CA3-group were $5.3\%\;and\;9.5\%$ lower than that of HC-group, respectively, while there was no significant difference in feed intakes, feed efficiency ratio and organs weight Level of serum triglyceride in $C_3-group\;was\;21\%$ lower than that of HC-group. Level of serum total cholesterol and LDL-cholesterol in CA2- and CA3-group were $22.1\~22.7\%\;and\;58.6\~64.3\%$ lower than those of HC-group, respectively. Atherogenic index decreased with the higher level of CA. Level of lipid peroxide in CA3-group was $24\%$ lower than that of HC-group, while there was no significant difference in GSH(Glutathione-S-transferase) content O type activities of XOD(xanthine oxidase) in the treated groups were lower, especially the activity in CA3-group was $51.6\%$ lower than that of HC-group. Also, O/T ratio of XOD was lower, showing $21.7\~23.5\%$ in treated groups and $34.0\%$ in HC-group(p<0.05). GST activities were 332.52 units in HC-group and $350.28\~355.63$ units in the treated groups, but there were no significant differences among them.

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THE EFFECT OF MISSING TEETH, PROSTHESIS AND MALALIGNMENT ON THE SMILE (치아결손, 보철물의 장착 및 치열부정이 미소에 끼치는 영향에 관한 연구)

  • Koh Joon-Won;Jin Tai-Ho;Dong Jin-Keun
    • The Journal of Korean Academy of Prosthodontics
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    • v.31 no.4
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    • pp.542-548
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    • 1993
  • This study was designed to investigate the effect of missing teeth, prosthesis and malalignment on the smile. The full smile photographs of 145 Korean adults(male 114 : female 31) were taken and classified by the lip pattern, the relationship between the lip and the teeth, and the number of teeth displayed in a smile. Besides, the esthetic smile score were estimated by five dentists. Obtained data were compared and analyzed. The results obtained were as follows : 1. The esthetic level of missing teeth group and malaligned group was lower than that of the normal group. 2. The esthetic level of prosthesis group had no difference with that of the normal group. 3. The Number of teeth displayed in a smile had the most effect on the esthetic level in each experimental group.

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Effect of Dietary Protein Level on Ca Efficiency in Bone Mineral Density in Growing Rats (식이단백질량이 성장기 흰쥐가 골밀도에 대한 칼슘효율에 미치는 영향)

  • 정소형
    • Journal of Nutrition and Health
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    • v.28 no.9
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    • pp.817-824
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    • 1995
  • This study was performed to evaluate the effect of dietary protein level on Ca efficiency in bone mineral density in growing male rats. Twenty male rate were divided into two groups. The rats in one group were fed on casein 20% diet as control group and the others were fed on casein 40% diet as protein group. All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. The total body, spine and femur bone mineral density and bone mineral content were measured using dual energy-x ray absorptiometry. Urinary calcium, phosphate, pyridinoline and creatinine, serum calcium, phosphate, total protein, albumin, alkaline phosphatase(ALP) and osteocalcin were measured. Urinary Ca excretion, pyridinoline and crosslinks value and serum ALP content seem to be increased in high protein group. It appears that the growing rats in high protein group had a higher bone resprption and bone formation than those in control group. Animal fad a high protein diet had a siginficantly higher Ca efficiency in BMD, BMC of total body, spine and femur. The results of this show that increasing of dietary protein level (40%) is beneficial of improvement of Ca efficiency during growing period.

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Effects of Magnesium Supplement Levels and Periods on Lipid Metabolism and Enzyme Activities in Rats (저단백식이와 마그네슘 결핍식이 섭취시 마그네슘 보충이 흰쥐의 지질대사 및 효소 활성에 미치는 영향)

  • 정복미
    • Journal of Nutrition and Health
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    • v.26 no.8
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    • pp.933-941
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    • 1993
  • The present study was carried out to investigate the effects of magnesium supplement levels and periods on lipid metabolism in male Sprague-Dawley rats given low protein and magnesium deficient diets. The effect of magnesium supplement levels and periods on lipid metabolism in rats given a low protein and magnesium deficient diet for 2 weeks were investigated. Serum total lipid and triglyceride contents were significantly lower in magnesium supplement group compared with magnesium deficient group. Serum HDL-cholesterol/total cholesterol ratio was significantly increased as magnesium supplement level was increased. Liver total lipid, triglyceride, total cholesterol and phospholipid contents were significantly lower in magnesium supplement group than those in magnesium deficient group. Serum ALP, GOT and GPT activities were significantly decreased in magnesium supplement group compared with magnesium deficient group. In summary, the effect of magnesium supplement on lipid metabolism and enzyme activities were significant and we can see that magnesium supplement level propered to be requirement level(400 mg/kg diet)in the other cases except serum lipid contents.

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Relationship Between the Dose of Clodronate and Serum Level of Alkaline Phosphatase, Calcium, and Phosphate During Orthodontic Tooth Movement

  • Choi, Josefina;Baek, Seung-Hak;Chang, Young-Il
    • Journal of Korean Dental Science
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    • v.3 no.1
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    • pp.32-38
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    • 2010
  • Objective : To evaluate the relationship between the dose of Clodronate and serum level of alkaline phosphatase (ALP), calcium (Ca), and phosphate (PO4) during orthodontic tooth movement MaterialS and MethodS: A total of 18 sex-matched Wistar rats (weight=180~230g, mean age=8 weeks) were allocated into the 2.5mM Clodronate (2.5C) group, 10mM Clodronate (10C) group, or control group (n=6 for each group). After the application of a nickel-titanium closed coil spring (force of 60g) between the upper central incisors and first molars (UFM), 2.5C, 10C, or saline was injected every third day into the subperiosteum of the alveolar bone adjacent to UFM for the experimental and control groups. The animals were sacrificed 17 days later. Trunk blood was quickly collected into a heparinized tube and centrifuged at 2,000 rpm for 20 min. The plasma was used for the biochemical assays of the serum level of ALP, Ca, and PO4. Kruskall-Wallis test and Mann-Whitney test with Bonferroni correction were performed for the statistical analyses. Results : Dose-dependent increase in the level of ALP (P<0.01) and decrease in the level of Ca (P<0.001) were observed among the control, 2.5C, and 10C groups. Although there was no significant difference in PO4 between the 2.5C and 10C groups, the 10C group showed a significantly higher level of PO4 than the control group (P<0.01). Conclusion : Since Clodronate induced significant dose-dependent change in the serum level of ALP, Ca, and PO4 during orthodontic tooth movement, orthodontists should consider these biochemical markers not only as a diagnostic tool for bone turnover rate but also as a monitoring tool for orthodontic tooth movement.

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Effects of Yogurt Containing Fermented Pepper Juice on the Body Fat and Cholesterol Level in High Fat and High Cholesterol Diet Fed Rat

  • Yeon, Su-Jung;Hong, Go-Eun;Kim, Chang-Kyu;Park, Woo Joon;Kim, Soo-Ki;Lee, Chi-Ho
    • Food Science of Animal Resources
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    • v.35 no.4
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    • pp.479-485
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    • 2015
  • This experiment investigated whether yogurt containing fermented pepper juice (FPJY) affects cholesterol level in high fat and high cholesterol diet (HFCD) fed rat. Twenty five Sprague-Dawley male rats of 7 wk were divided into 5 groups, and fed following diets for 9 wk; CON (control diet), HFCD (HFCD), PY (HFCD supplemented with 2% of plain yogurt), LFY (HFCD supplemented with 2% of FPJY), and HFY (HFCD supplemented with 5% of FPJY). In the LFY group, hepatic total lipid level decreased significantly compared to the HFCD group (p<0.05). Serum HDL cholesterol level tended to increase and hepatic total cholesterol level decreased and were comparable to the CON group (p>0.05). In HFY group, body weight and hepatic total lipid level significantly decreased over the HFCD group (p<0.05). Serum and hepatic total cholesterol level, kidney, and body fat weights decreased, and were compared to the CON group (p>0.05). Liver weight decreased as FPJY content was increased. Results suggested FPJY would inhibit organ hypertrophy and accumulation of body fat, hepatic lipid, and cholesterol in HFCD fed rat.

The Effects of the Presentation of Self-Made Problems on the Enhancement of Scholastic Achievement in Mathematics and Logicial Thinking (자작문제 발표방식이 수학과 학력신장에 미치는 영향)

  • 류재환
    • Journal of the Korean School Mathematics Society
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    • v.1 no.1
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    • pp.139-149
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    • 1998
  • The purpose of this study is to check out whether the method that students make problems and anouence them to both students and teacher in the next class influence on the students' intersts, attitudes, logical thinking ability and lerning achievement in mathematics. The following is the experimental design and procedure. First, the author divided students into two groups. One is the experimental group and the other is the control group. These two groups' students consist of the advanced level, the intermediate level and the elementary level according to the students' learning proficiency Second, the author used the different teaching method between the experimental group and the control group. The author gave the experimental group's students the learning assignment problems according to their three levels and made students present the problems to the instructor and classmates in the next class. On the other hand, the author gave the control group's students learning assignment problems according to their three levels, and made them only submit their assingment to the instructor. The results of this study are as follows : 1)The method of solving and presenting the self-made problems on the basis of the informations to solve the given preceding model learning problems according to students' levels made students' learning attitudes more positive even though the method couldn't enhance the students' interests in mathematics. 2)The method of solving and presenting the self-made problems was effective to improve the logical thinking ability for especially the intermediate level's students among the three levels. In addition, the intermediate level's students showed great positive changes in their improvements of the learning achievment. It is assumed that this result is caused by two major factors(reasons). One is students' confidence that they can solve the fundamental problems without difficulty. And the other is students' desire to solve the problems of the intermediate level or more advanced level.

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Influence of Autologous and Homologous Blood Transfusion on Interleukins and Tumor Necrosis Factor-α in Peri-operative Patients with Esophageal Cancer

  • Xing, Yue-Li;Wang, Yan-Chun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7831-7834
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    • 2014
  • Objective: To explore the influence of different ways of blood transfusion on the expression levels of interleukins (IL) and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) inperi-operative patients with esophageal cancer. Materials and Methods: A total of 80 patients with esophageal cancer who underwent radical operations were selected as study patients and randomly divided into an observation group (treated with autologous blood transfusion) and control group (with homologous blood transfusion). Changes of intra-operative indexes and peri-operative blood indexes, from hemoglobin (Hb) and hematocrit value (Hct), to levels of inflammatory factors like interleukins-6 (IL-6), IL-8, IL-10 and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) were compared. Results: Operations for patients in both groups were successfully conducted, and no significant differences in mean surgical duration and intra-operative hemorrhage volume, fluid infusion volume and blood transfusion volume were detected (p>0.05). Compared with values before surgery, Hb and Hct levels decreased significantly while white blood cell count (WBC) increased 1, 5 and 7 d after operation (p<0.05, p<0.01). In addition, WBC was apparently higher in observation group than in control group 5 and 7 d after operation (p<0.01). Compared with before surgery, in the observation group, levels of IL-6, IL-8 and IL-10 had no significant differences after operation (P>0.05), but TNF-${\alpha}$ level increased y (p<0.01), whereas in control group, IL-6 level had no significant difference (p>0.05), IL-8 level decreased obviously (p<0.05), IL-10 level increased markedly first and then decreased gradually as time passed but its level remained elevated (p<0.01), and TNF-${\alpha}$ level increased first and then decreased, and there was no significant difference 7 d after operation (p>0.05). Conclusions: Decreased IL-8 and increased IL-10 levels are two important reasons for immunosuppression after homologous blood transfusion, whereas autologous blood transfusion can alleviate this while increasing the TNF-${\alpha}$ level, which also has potential to improve anti-tumor immunity in the human body.

Body cathexis and Clothing Behavior of Middle-aged Women according to the Depression Level (중년기 여성의 우울도에 따른 신체만족도 및 의복행동)

  • Lee, Jungeun;Choi, Hyojin;Shin, Bongjin;Park, Soonjee
    • Fashion & Textile Research Journal
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    • v.18 no.2
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    • pp.207-215
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    • 2016
  • This research was designed to analyze the relationship among depression level, body cathexis, and clothing behavioral attributes of middle-aged women. Respondents for questionnaire were middle-aged women aged from 40 to 59. A total of 197 responses were analyzed by SPSS 21.0 through t-test, and factor analysis with Varimax rotation. The results were as following. As older, the portion of depressed group increased. Higher in depression level, her body cathexis decreased, meaning those two valuables have negative relationship. Six clothing behavioral factors were extruded: style pursuit, body shaping, showing-off, comfort pursuit, recreativeness, and consciousness of others factor, which covers both physical and psychological aspects of middle-aged women. The difference between 40's and 50's was significant in depression level, however, not significant in body cathexis and clothing behavioral attributes. Except for weight, body cathexis satisfaction level of 'depressed group' were significantly lower than 'not-depressed group', meaning that psychological factor give a significant effect on body cathexis. 'Not-depressed group' tend to choose her own style and 'depressed group' more likely to be conscious of others and conform to the affiliation group. This finding implies that design and coordination of garments for middle-aged women could be recommended according to the depression level to improve the quality of life.

The Effect of a Telephone follow-up on the Self-care and the Satisfaction on Nursing Care in G-I Surgical Patients (전화추후관리가 위,장관계 수술환자의 자기간호수행 및 환자만족도에 미치는 효과)

  • Na, In-Jae;Lee, Byung-Sook
    • Journal of Korean Academy of Nursing Administration
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    • v.5 no.2
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    • pp.355-368
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    • 1999
  • This study was a quasi-experimental study to investigate the effect of a telephone follow-up on the self-care and the satisfaction on nursing care in G-I surgical patients. The subjects of the study were 38 patients, 19 in experimental group and 19 in control group, who discharged after gastrointestinal surgery at a university hospital in Taegu between August 11. 1998 and October 16, 1998. The telephone follow-up program for the experiment was developed by the researcher, which contained consultation, support and encouragement for self-care after discharge. Number of the instruments used for measurement of the outcome variables were 5, self-care after discharge, satisfaction(1)${\sim}$(2) on Nursing care. intention to visit the hospital again. intention to recommend the hospital to others. The results of this study were as follows ; 1. The first hypothesis, "The subjects of experimental group will show a higher level of self-care than the subjects of control group" was rejected (F=.48. p=.4937). 2. The Second hypothesis. "The subjects of experimental group will show a higher level of satisfaction than the subjects of control group" was accepted partly as follows. 1) The hypothesis 2-1, "The subjects of experimental group will show a higher level of satisfaction(1) than the subjects of control group" was accepted(F=4.04. p=.0496). 2) The hypothesis 2-2. "The subjects of experimental group will show a higher level of satisfaction(2) than the subjects of control group" was accepted(F=8.48. p=.0064). 3) The hypothesis 2-3, "The subjects of experimental group will show a higher level of intention to visit hospital again than the subjects of control group" was rejected(F=1.95. p=.1723). 4) The hypothesis 2-4. "The subjects of experimental group will show a higher level of intention to recommend the hospital to others than the subjects of control group" was rejected(F=1.43. p=.2411) . From the results of this study, the telephone follow-up can be regarded as an effective nursing intervention for the discharged patients.

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