• 제목/요약/키워드: grafting process

검색결과 126건 처리시간 0.03초

가토 상악동 거상술 후 Bovine Bone (Bio-$Oss^{(R)}$)과 함께 이식된 혈소판풍부혈장과 혈소판결핍혈장의 골치유능 비교 (Effect of bovine bone (Bio-$Oss^{(R)}$) and platelet rich plasma, platelet poor plasma on sinus bone graft in rabbit)

  • 이태형;정유민;최용근;이의석;장현석;임재석
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제36권1호
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    • pp.39-42
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    • 2010
  • Maxillary sinus lift and bone graft are used to reconstruct atrophic maxilla molar area for endosseous dental implants. Many different grafting materials and techniques can be used for maxillary sinus bone graft. Bio-$Oss^{(R)}$ has been proposed as bone substitute and successfully utilized as osteoconductive filler. Platelet rich plasma (PRP) is an autologous material with many growth factors, such as PDGF, TGF-$\beta$, IGF, VEGF, facilitating bone healing process. And Platelet poor plasma (PPP) is the by-product in procedure of producing PRP. Six rabbits were used as experimental animal. Both maxillary sinus were grafted with Bio-$Oss^{(R)}$ and PRP, and Bio-$Oss^{(R)}$ and PPP. Rabbits were sacrificed at 4, 8 and 12 weeks. The grafting sites were evaluated by histomorphometric analysis. As a result, using PRP showed excellent bone formation in the early stage, but no further significant effect after that. In late stage, the ability of bone formation of using PRP was even worse than using PPP. The further studies need to be considered in this case.

Acrylic Acid-Grafted Hydrophilic Electrospun Nanofibrous Poly(L-lactic acid) Scaffold

  • Park, Kwi-Deok;Jung, Hyun-Jung;Kim, Jae-Jin;Ahn, Kwang-Duk;Han, Dong-Keun;Ju, Young-Min
    • Macromolecular Research
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    • 제14권5호
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    • pp.552-558
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    • 2006
  • Biodegradable nanofibrous poly(L-lactic acid) (PLLA) scaffold was prepared by an electrospinning process for use in tissue regeneration. The nanofiber scaffold was treated with oxygen plasma and then simultaneously in situ grafted with hydrophilic acrylic acid (AA) to obtain PLLA-g-PAA. The fiber diameter, pore size, and porosity of the electrospun nanofibrous PLLA scaffold were estimated as $250\sim750nm,\;\sim30{\mu}m$, and 95%, respectively. The ultimate tensile strength was 1.7 MPa and the percent elongation at break was 120%. Although the physical and mechanical properties of the PLLA-g-PAA scaffold were comparable to those of the PLLA control, a significantly lower contact angle and significantly higher ratio of oxygen to carbon were notable on the PLLA-g-PAA surface. After the fibroblasts were cultured for up to 6 days, cell adhesion and proliferation were much improved on the nanofibrous PLLA-g-PAA scaffold than on either PLLA film or unmodified nanofibrous PLLA scaffold. The present work demonstrated that the applications of plasma treatment and hydrophilic AA grafting were effective to modify the surface of electrospun nanofibrous polymer scaffolds and that the altered surface characteristics significantly improved cell adhesion and proliferation.

반응 압출을 통한 PP-g-MA 제조 및 특성평가 (Preparation and Characterization of Grafted Maleic Anhydride onto Polypropylene by Reactive Extrusion)

  • 강동진;이성효;;박찬영;장진수;방대석;김진국
    • 폴리머
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    • 제33권4호
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    • pp.358-363
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    • 2009
  • 반응성기를 가지는 산무수물(maleic anhydride, MAH)을 폴리프로필렌(PP)에 도입함으로써 PP/극성 고분자의 블렌드 및 PP/filler의 복합소재 제조에서 계면과 계면 사이에 물리적 결합 이외의 화학적 결합을 향상시키고 기계적 특성 및 열적 특성을 극대화할 수 있다. 본 실험에서는 개시제(di-cumyl periofide, DCP)와 MAH 함량에 따른 그래프트율을 FT-IR과 화학적 적정법(chemical titration)을 이용하여 측정하였다. 그 결과 MAH의 함량이 증가할수록 그래프트율이 증가하였고 DCP의 함량이 0.06 wt% 일때에 가장 높은 그래프트율을 나타내었다. 또한, MAH의 함량에 따라 용융 흐름지수(melt index)가 증가하는 것을 볼 수 있었으며, 용융온도 및 열 분해 등의 열적 거동은 시차주사열량계(DSC) 및 열중량 분석기(TGA)를 이용하여 MAH 그래프트율에 따른 변화를 분석하였다.

관상동맥우회술 환자에서 술 전 백혈구 수치가 수술 후 경과에 미치는 영향 (Effect of Preoperative White Blood Cell Count on Postoperative Course in Patients with Coronary Artery Bypass Grafting)

  • 손국희;김재호;김정택;윤용한;김광호;백완기
    • Journal of Chest Surgery
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    • 제38권10호
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    • pp.669-674
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    • 2005
  • 배경: 동맥경화가 일종의 염증성 반응에 의해 매개된다는 이론을 바탕으로 여러 연구에서 백혈구 수치의 증가가 심혈관 질환에 의한 사망에 영향을 준다는 결과가 보고되고 있다. 같은 맥락에서 관상동맥우회술 시에도 수술 전 백혈구 수치가 수술 후 사망의 독립예측변수라는 보고들이 있다. 저자들은 본 연구를 통해 관상동맥우회술시 수술 전 백혈구 수치가 수술 후 사망 및 합병증 발생에 있어 과연 어떤 영향을 미치는가를 알아보고자 하였다. 대상 및 방법 : 1996년부터 2003년까지 인하대병원 흉부외과에서 단독 관상동맥우회술(isolated coronary artery bypass grafting)을 시행한 환자 133명을 대상으로 의무 기록의 후향적 분석을 시행하였다. 수술 전 백혈구 수에 따라 환자들을 오름차순으로 배열한 후 균등하게 A, B, C, D군의 네 군으로 나누었을 때 수술 전 백혈구 수치의 범위는 A군은 $1.3\times10^3/{\mu}L$에서 $5.9\times10^3/{\mu}L$까지, B군은 $6.0\times10^3/{\mu}L$에서 $7.0\times10^3/{\mu}L$까지 C군은 $7.1\times10^3/{\mu}L$에서 $8.9\times10^3/{\mu}L$까지 D군은 $8.9\times10^3/{\mu}L$에서 $16.9\times10^3/{\mu}L$까지로 환자 수는 A군만 34명을 포함시켰으며 나머지 군은 모두 33명으로 동일하였다. 결과: 수술 전 심근경색이 선행된 환자 수는 A군에서는 0명, B군 2명$(6.1\%)$, C군 4명$(12.1\%)$, D군 8명$(24.3\%)$으로 백혈구 수가 높은 군일수록 심근경색이 선행된 환자 수가 많음이 입증되었다(p<0.01). 수술 후 사망 예는 모두 6예로, A군 1명$(2.9\%)$, B군 1명$(3.0\%)$, C군 2명$(6.1\%)$, D군 2명$(6.1\%)$으로 각 군에 따른 유의한 차이는 보이지 아니하였다(p=0.44). 수술 후 창상 감염은 3명의 환자에서 발생하였는데 3명 모두 D군에서 발생하였다. 결론: 관상동맥우회술 환자에서 수술 전 백혈구 수치와 술 후 사망간의 연관 관계는 찾을 수 없었다. 술 전 백혈구 수치가 높은 군에서 술 후 창상 감염의 빈도가 증가하였다.

PVA-g-PAA 가지형 공중합체 기반 촉진수송 분리막 (Facilitated Transport Membranes Based on PVA-g-PAA Graft Copolymer)

  • 박민수;강미소;박보령;김정훈;김종학
    • 멤브레인
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    • 제31권3호
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    • pp.212-218
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    • 2021
  • 화석 연료를 사용할 때, 불완전 연소는 필연적으로 발생하는 문제이다. 이러한 관점에서 연소 후 기체 분리는 불완전 연소 기체의 재활용 가능성을 시사한다. 이와 관련하여 본 연구에서는 일산화탄소 기체 분리용 촉진수송 고분자 분리막을 제조하였다. 이를 위해 poly(vinyl alcohol) (PVA) 주사슬 기반으로 acrylic acid (AA) 단량체를 자유 라디칼 중합법으로 PVA-g-PAA 공중합체를 제조하였다. 본 공중합체를 일산화탄소 활용에 적용하는 사례는 처음이며, 제조한 공중합체는 AgBF4 염과 HBF4를 혼합하여 기체 분리막에 적용하였다. 공중합체 합성 결과는 FT-IR을 통해 분석하였으며, 공중합체와 AgBF4, HBF4의 상호작용은 TEM를 통해 분석하였다. 염의 첨가를 통해 일산화탄소 기체의 촉진수송 채널을 형성하였으며 이를 통해 일산화탄소 분리막 분야에 촉진수송 및 그래프팅 방법이라는 새로운 접근법을 제시하였다.

Lifetime Prolongation of Poly (dimethylsiloxane) Surface Modification via 2-Hydroxyethyl Methacrylate Grafting for Electroosmotic Flow

  • Park, Eun-Soo;Yang, Sang-Sik
    • KIEE International Transactions on Electrophysics and Applications
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    • 제4C권4호
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    • pp.142-144
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    • 2004
  • To use Poly-dimethylsiloxane (PDMS) for the electrokinetic flow channel, the PDMS surface must be modified to be hydrophilic. With $O_2$ plasma treatment, it is difficult to maintain hydrophilicity for more than one day. In this paper, we present the chemical modification of the PDMS surface using 2-Hydroxyethyl methacrylate (HEMA) to prolong hydrophilicity lifetime. The oxide radicals generated temporarily on the PDMS surface by $O_2$ plasma are grafted with HEMA. Once the PDMS samples have been grafted, they demonstrate improved hydrophilicity retainment and electroosmotic flow characteristics compared to the untreated PDMS and the oxidized PDMS following the $O_2$ plasma process. This phenomenon was verified by the contact angles, Fourier transform infrared (FTIR) spectra and electro osmotic flow rates observed for more than 300 hours.

뽕나무 묘목생산을 위한 신소삽목 조건 구명 (Studies on the Conditions of Softwood Cutting for Production of Mulgerry Sapling)

  • 구태원;성규병
    • 한국잠사곤충학회지
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    • 제39권2호
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    • pp.101-105
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    • 1997
  • Most of the mulberry saplings in Korea have been produced by grafting. But the production of mulberry sapling by this method is very complex process and requires high level of technique and two years to produce saplings. Therefore, to develop the mulberry sapling production system by softwood cutting method which is suitable for mass production, several conditions on rooting and growth of cuttings were investigated. The rooting ability of cuttings varied according to mulberry varieties, showing the highest rooting ratio of 93.3% in cultivar of Shingwangppong. Of different soil texture as for rooting media, the clay was found to be the best; other media decreased in order as follows; sand, sand loam and vermiculite. The shading ratio by 70% with polyethylene film showed the highest rooting ratio of the cuttings. Optimum day of cutting was around 50th day after sprouting, whereas the ratio of stem thicker than 7mm at the base of saplings in diameter was highest at 44th day.

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Plasma and VUV Pretreatments of Polymer Surfaces for Adhesion Promotion of Electroless Ni or Cu Films

  • Romand, M.;Charbonnier, M.;Goepfert, Y.
    • 접착 및 계면
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    • 제4권2호
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    • pp.10-20
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    • 2003
  • This paper is relative to the electroless deposition of nickel or copper films on polyimide and polytetrafluoroethylene substrates. First, it is presented an original approach of the electroless process which consists in grafting nitrogenated functionalities on the polymer surfaces via plasma or VUV-assisted treatments operating in a nitrogen-based atmosphere ($NH_3$, $N_2$), and then in catalysing the grafted surfaces in an aqueous tin-free, Pd(+2)-based solution. Adhesion of the Pd(+2) catalytic species on polymer surfaces is explained by the formation of strong covalent bonds between these species and the grafted nitrogenated groups. Second, it is show how a fragmentation test performed in conjunction with electrical measurements can be used to characterize the practical adhesion of the electroless coatings deposited on flexible polymer substrates, and to evidence the influence of some experimental parameters (plasma treatment time and nature of the gas phase).

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Apatite Formation on Polythylene Modified with Silanols by Grafting of Vinyltrimethoxysilane and Subsequent Hydrolysis

  • Kokubo, Tadashi;Uenoyama, Mayo;Kim, Hyun-Min;Minoda, Masahiko;Miyamoto, Takeaki;Nakamura, Takashi
    • The Korean Journal of Ceramics
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    • 제5권3호
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    • pp.265-269
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    • 1999
  • Polyethylene was modified with silanol groups on its surface by photografting of vinyltrimethoxysilane in vapor phase by using benzophenon as a polymerization initiator and by hydrolyzing the methoxysilane groups into the silanol groups with HCI solution. The modified polyethylene formed a dense and homogeneous apatite layer on its surface in a solution with ion concentrations 1.5 times those of human blood plasma within 21 days. This kind of biomimetic process could provide techniques for fabricating apatite-polymer composites with three dimensional structure analogous to the natural bone.

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RFID/USN 기반의 유비쿼터스 제조실행시스템 설계 및 구현 (Design and Implementation of an Ubiquitous Manufacture Execution System based on RFID/USN)

  • 정세훈;김경종;심춘보
    • 디지털산업정보학회논문지
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    • 제6권4호
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    • pp.21-31
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    • 2010
  • A manufacturing execution system in the process according to automation system of installation management has been growing interest about effective system design and effective system manage. In this paper, we propose an ubiquitous Manufacturing Execution System based on RFID/USN for checkup monitoring and history management of installation in manufacturing execution systems. For this, we design and implement installation history and statistics management system based on RFID grafting RFID for efficient installation equipment history and statistics management of ubiquitous Manufacturing Execution System, and was implemented checkup monitoring system based on USN using temperature sensor, humidity sensor, hydraulic pressure sensor for failure prevention of ubiquitous Manufacturing Execution System. And proposed ubiquitous Manufacturing Execution System is implemented based on JSP for access through Web in real time.