• Title/Summary/Keyword: gradient domain

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Dpp Represses eagle Expression at Short-Range, but Can Repress Its Expression at a Long-Range via EGFR Signal Repression

  • Kim, Se Young;Jung, Keuk Il;Kim, Sang Hee;Jeon, Sang-Hak
    • Molecules and Cells
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    • v.26 no.6
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    • pp.576-582
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    • 2008
  • Nervous system development takes place after positional information has been established along the dorsal-ventral (D/V) axis. The initial subdivision provided by a gradient of nuclear dorsal protein is maintained by the zygotic genes expressed along the D/V axis. In this study, an investigation was conducted to determine the range of Dpp function in repressing the expression of eagle (eg) that is present in intermediate neuroblasts defective (ind) and muscle specific homeobox (msh) gene domain. eg is expressed in neuroblast (NB) 2-4, 3-3 and 6-4 of the msh domain, and NB7-3 of the ind domain at the embryonic stage 11. In decapentaplegic (dpp) loss-of-function mutant embryos, eg was ectopically expressed in the dorsal region, while in dpp gain-of-function mutants produced by sog or sca-GAL4/UAS-dpp, eg was repressed by Dpp. It is worthy of note that Dpp produced from sim;;dpp embryos showed that Dpp could function at long range. However, Dpp produced from en-GAL4/UAS-dpp or wg-GAL4/UAS-dpp primarily acted at short-range. This result demonstrated that this discrepancy seems to be due to the repression of Dpp to EGFR signaling in sim;;dpp embryos. Taken together, these results suggest that Dpp signaling works at short-range, but can function indirectly at long-range by way of repression of EGFR signaling during embryonic neurogenesis.

Conjugate Heat Transfer Analysis of High Pressure Turbine with Secondary Flow Path and Thermal Barrier Coating (2차유로 및 열차폐 코팅을 고려한 고압터빈의 열유동 복합해석)

  • Kang, Young-Seok;Rhee, Dong Ho;Cha, Bong Jun
    • The KSFM Journal of Fluid Machinery
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    • v.18 no.6
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    • pp.37-44
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    • 2015
  • Conjugate heat analysis on a high pressure turbine stage including secondary flow paths has been carried out. The secondary flow paths were designed to be located in front of the nozzle and between the nozzle and rotor domains. Thermal boundary conditions such as empirical based temperature or heat transfer coefficient were specified at nozzle and rotor solid domains. To create heat transfer interface between the nozzle solid domain and the rotor fluid domain, frozen rotor with automatic pitch control was used assuming that there is little temperature variation along the circumferential direction at the nozzle solid and rotor fluid domain interface. The simulation results showed that secondary flow injected from the secondary flow path not only prevents main flow from penetrating into the secondary flow path, but also effectively cools down the nozzle and rotor surfaces. Also thermal barrier coating with different thickness was numerically implemented on the nozzle surface. The thermal barrier coating further reduces temperature gradient over the entire nozzle surface as well as the overall temperature level.

Topology Optimization of an Acoustic Diffuser Considering Reflected Sound Field (반사 음장을 고려한 음향 확산 구조의 위상 최적 설계)

  • Yang, Jieun;Lee, Joong Seok;Kim, Yoon Young
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.23 no.11
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    • pp.973-981
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    • 2013
  • The main role of an acoustic diffuser is to diffuse reflected sound field spatially. Since the pioneering work of Schroeder, there have been investigations to improve its performance by using shape/sizing optimization methods. In this paper, a gradient-based topology optimization algorithm is newly presented to find the optimal distribution of reflecting materials for maximizing diffuser performance. Time-harmonic acoustic analysis in a two-dimensional acoustic domain is carried out where the domain is discretized by finite elements. Perfectly matched layers are placed to surround the domain to simulate non-reflecting boundary conditions. Design variables are assigned to each element of which material properties are interpolated between those of air and those of a rigid body. An approach to extract the reflected field from the total acoustic field is employed. To validate the effectiveness of the proposed method, design problems are solved at different frequencies. The performance of the optimized diffusers obtained by the proposed method is compared against that of the conventional Schroeder diffusers.

Structural optimal control based on explicit time-domain method

  • Taicong Chen;Houzuo Guo;Cheng Su
    • Structural Engineering and Mechanics
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    • v.85 no.5
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    • pp.607-620
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    • 2023
  • The classical optimal control (COC) method has been widely used for linear quadratic regulator (LQR) problems of structural control. However, the equation of motion of the structure is incorporated into the optimization model as the constraint condition for the LQR problem, which needs to be solved through the Riccati equation under certain assumptions. In this study, an explicit optimal control (EOC) method is proposed based on the explicit time-domain method (ETDM). By use of the explicit formulation of structural responses, the LQR problem with the constraint of equation of motion can be transformed into an unconstrained optimization problem, and therefore the control law can be derived directly without solving the Riccati equation. To further optimize the weighting parameters adopted in the control law using the gradient-based optimization algorithm, the sensitivities of structural responses and control forces with respect to the weighting parameters are derived analytically based on the explicit expressions of dynamic responses of the controlled structure. Two numerical examples are investigated to demonstrate the feasibility of the EOC method and the optimization scheme for weighting parameters involved in the control law.

Modification of Wind Generated Coastal Circulation Model (풍성연안순환모델의 수정)

  • Lee, J. W.;Shin, S. H.;Kim, J. Y.;Yang, S. Y.
    • Journal of Korean Port Research
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    • v.9 no.2
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    • pp.25-38
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    • 1995
  • The wind generated circulation model describes the phenomenon based on the following physical assumptions: a) As the horizontal dimension of the flow domain is several orders of magnitude larger than vertical dimension, nearly horizontal flow is realistic. b) The time taken for circulation to develop may effect on the flow domain of the earth's rotation, the contribution of the Coriolis force. c) A flow domain of large dimension results in quite large Reynolds number and the Reynolds stresses are approximated by the turbulent mean velocity gradient. d) The circulation is forced by the shear stresses on the water surface exercised by the wind. Modification made to the depth average approximation of the convective terms and the bed shear stress terms by adopting a certain distribution of current over the depth and laboratory measurements for the bed shear expression. Modification circulation patterns, energy evolution and surface profile gave the significant differences comparing with the classical model results. The modified model results in higher free surface gradients balancing both the free surface shear and the bed shear and consequently to higher surface profiles along the coast.

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Application of Displacement-Vector Objective Function for Frequency-domain Elastic Full Waveform Inversion (주파수 영역 탄성파 완전파형역산을 위한 변위벡터 목적함수의 적용)

  • Kwak, Sang-Min;Pyun, Suk-Joon;Min, Dong-Joo
    • Geophysics and Geophysical Exploration
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    • v.14 no.3
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    • pp.220-226
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    • 2011
  • In the elastic wave equations, both horizontal and vertical displacements are defined. Since we can measure both the horizontal and vertical displacements in field acquisition, these displacements compose a displacement vector. In this study, we propose a frequency-domain elastic waveform inversion technique taking advantage of the magnitudes of displacement vectors to define objective function. When we apply this displacement-vector objective function to the frequency-domain waveform inversion, the inversion process naturally incorporates the back-propagation algorithm. Through the inversion examples with the Marmousi model and the SEG/EAGE salt model, we could note that the RMS error of the solution obtained by our algorithm decreased more stably than that of the conventional method. Particularly, the density of the Marmousi model and the low-velocity sub-salt zone of the SEG/EAGE salt model were successfully recovered. Since the gradient direction obtained from the proposed objective function is numerically unstable, we need additional study to stabilize the gradient direction. In order to perform the waveform inversion using the displacementvector objective function, it is necessary to acquire multi-component data. Hence, more rigorous study should be continued for the multi-component land acquisition or OBC (Ocean Bottom Cable) multi-component survey.

The Mixed Finite Element Analysis for Porous Media using Domain Decomposition Method (영역 분할기법을 이용한 포화 다공질매체의 혼합유한요소해석)

  • Lee, Kyung-Jae;Tak, Moon-Ho;Kang, Yoon-Sik;Park, Tae-Hyo
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.23 no.4
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    • pp.369-378
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    • 2010
  • The mixed finite element analysis is the most widely used method for saturated porous media. Generally, in this method, direct method and iterative method are proposed to obtain unknown variable, however, the iterative method is recommended because the method provide numerical stability and accuracy under the material properties for solid and fluid are different. In this paper, we introduce staggered method which has strong numerical stability, and FETI(Finite Element Tearing and Interconnecting) which is one of decomposition methods are applied into the method in order to obtain numerical efficiency. In which, Lagrange Multipliers and conjugated gradient method to solve decomposed domain are proposed, and then, the proposed method is verified numerical efficiency by point to point MPI(Message Passing Interface) library.

Automatic fingerprint recognition using directional information in wavelet transform domain (웨이블렛 변환 영역에서의 방향 정보를 이용한 지문인식 알고리즘)

  • 이우규;정재호
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.22 no.10
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    • pp.2317-2328
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    • 1997
  • The objective of this paper is to develop an algorithm for a real-time automatic fingerprint recognition system. The algorithm employs the wavelet transform(WT) and the dominat local orientation that derived from the gradient Gaussian(GoG) and coherence in determining the directions of ridges in fingerprint images. By using the WT, the algorithm does not require conventional preprocessing procedures such as smothing, binarization, thining and restoration. For recognition, two fingerprint images are compared in three different ST domains;one that represents the original image compressed to quarter(LL), another that shows vertical directional characteristic(LH), and third as the block that contains horizontal direction(HL) in WT domain. Each block has dominat local orientation that derived from the GoG and coherence. The proposed algorithm is imprlemented on a SunSparc-2 workstation under X-window environment. Our simulation results, in real-time have shown that while the rate of Type II error-Incorrect recognition of two identical fingerprints as the identical fingerprints-is held at 0%, the rate of Type I error-Incorrect recognitionof two identical fingerprints as the different ones-is 2.5%.

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No-reference Image Blur Assessment Based on Multi-scale Spatial Local Features

  • Sun, Chenchen;Cui, Ziguan;Gan, Zongliang;Liu, Feng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.14 no.10
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    • pp.4060-4079
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    • 2020
  • Blur is an important type of image distortion. How to evaluate the quality of blurred image accurately and efficiently is a research hotspot in the field of image processing in recent years. Inspired by the multi-scale perceptual characteristics of the human visual system (HVS), this paper presents a no-reference image blur/sharpness assessment method based on multi-scale local features in the spatial domain. First, considering various content has different sensitivity to blur distortion, the image is divided into smooth, edge, and texture regions in blocks. Then, the Gaussian scale space of the image is constructed, and the categorized contrast features between the original image and the Gaussian scale space images are calculated to express the blur degree of different image contents. To simulate the impact of viewing distance on blur distortion, the distribution characteristics of local maximum gradient of multi-resolution images were also calculated in the spatial domain. Finally, the image blur assessment model is obtained by fusing all features and learning the mapping from features to quality scores by support vector regression (SVR). Performance of the proposed method is evaluated on four synthetically blurred databases and one real blurred database. The experimental results demonstrate that our method can produce quality scores more consistent with subjective evaluations than other methods, especially for real burred images.