Allen Wei-Jiat Wong;Nadia Hui Shan Sim;Coeway Boulder Thing;Wenxuan Xu;Hui Wen Chua;Sabrina Ngaserin;Shermaine Loh;Yee Onn Kok;Jia Jun Feng;Tan Woon Woon Pearlie;Benita Kiat-Tee Tan
Archives of Plastic Surgery
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v.51
no.5
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pp.504-509
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2024
The treatment of breast cancer has seen great success in the recent decade. With longer survivorship, more attention is paid to function and aesthetics as integral treatment components. However, breast cancer-related lymphedema (BCRL) remains a significant complication. Immediate lymphatic reconstruction is an emerging technique to reduce the risk of BCRL, the Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) being the most widely used approach. Despite promising results, it is often difficult to find suitably sized recipient venules and perform the micro-anastomoses between mismatched vessels deep in the axilla. Moreover, high axillary venous pressure gradients and potential damage from radiotherapy may affect the long-term patency of the anastomoses. From an ergonomic point of view, performing lymphaticovenular anastomosis in the deep axilla may be challenging for the microsurgeon. In response to these limitations, we modified the technique by moving the lymphatic reconstruction distally-terming it distally based LYMPHA (dLYMPHA). A total of 113 patients underwent mastectomy with axillary clearance in our institution from 2018 to 2021. Of these, 26 underwent subsequent dLYMPHA (Group 2), whereas 87 did not (Group 1). In total, 17.2% (15 patients) and 3.84% (1 patient) developed BCRL in Groups 1 and 2, respectively (p = 0.018). Lymphatics and recipient venules suitable for anastomoses can be reliably found in the distal upper limb with better size match. A distal modification achieves a more favorable lymphaticovenular pressure gradient, vessel match, and ergonomics while ensuring a comparably low BCRL rate.
Korean Journal of Agricultural and Forest Meteorology
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v.22
no.4
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pp.239-249
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2020
Rice flour varieties have been developed to replace wheat, and consumption of rice flour has been encouraged. damage related to pre-harvest sprouting was occurring due to a weather disaster during the ripening period. Thus, it is necessary to develop pre-harvest sprouting rate prediction system to minimize damage for pre-harvest sprouting. Rice cultivation experiments from 20 17 to 20 19 were conducted with three rice flour varieties at six regions in Gangwon-do, Chungcheongbuk-do, and Gyeongsangbuk-do. Survey components were the heading date and pre-harvest sprouting at the harvest date. The weather data were collected daily mean temperature, relative humidity, and rainfall using Automated Synoptic Observing System (ASOS) with the same region name. Gradient Boosting Machine (GBM) which is a machine learning model, was used to predict the pre-harvest sprouting rate, and the training input variables were mean temperature, relative humidity, and total rainfall. Also, the experiment for the period from days after the heading date (DAH) to the subsequent period (DA2H) was conducted to establish the period related to pre-harvest sprouting. The data were divided into training-set and vali-set for calibration of period related to pre-harvest sprouting, and test-set for validation. The result for training-set and vali-set showed the highest score for a period of 22 DAH and 24 DA2H. The result for test-set tended to overpredict pre-harvest sprouting rate on a section smaller than 3.0 %. However, the result showed a high prediction performance (R2=0.76). Therefore, it is expected that the pre-harvest sprouting rate could be able to easily predict with weather components for a specific period using machine learning.
The Buddha triad and 16 Arhat statues carved on the rock surface at Seongbulsa temple is the only domestic remaining example of all 16 Arhats, so its academic value is very high. However, it is severely damaged and so required a stability evaluation through study of digital documentation and precise diagnosis for the purpose of comprehensive conservation. This process established that the Buddha statues were of similar scale, while the Arhats showed a wide variety of sizes, and the two kith and kin in the volume were larger than the Arhats. It was estimated that the statues of food for Buddha are similar to the Arhat statues, and most of the statues are well-formed. The rock used to carve the Buddha statues is banded gneiss with distinct foliation, alternating between white bands of quartz and feldspar and black bands composed of biotite. The Buddha statues have been damaged by physical weathering, discoloration, and biological contamination. In damage evaluations, joint (3.6 crack index), peeling (5.2%), exfoliation (1.7%), and falling off (0.1%) were observed on the rock surface of the Buddha statues. In particular, due to severe biological weathering, stage 9 and 10 biological coverage of the rock surface accounted for 57.5% of the total area, and stages 5 to 8 also accounted for a high share at 22.3%. The discoloration factors were shown to be dark brown and white with Fe, Ca, and S, and a large amount of C detected in the blackened contaminants, and the damage weight high in all areas. Discontinuities in different directions were identified in the rock surface. Analysis of potential rock failure types indicated that there is a possibility of plane and toppling failure, but wedge failure is unlikely to occur. The mean ultrasonic velocity of the main rock surface was 2,463m/sec, the lower part of the left side with a large number of joints was relatively low, and the highly weathered (HW) type to the completely weathered (CW) type concentrated distribution, showing weak properties. For the Buddha statues, conservation treatment is required for about 14.9% of micro cracks and 58.9% of exfoliation cracks. In addition, in order to improve the conservation environment of the Buddha statues, maintenance of drainage and ground preparations for the rock surface gradient and plants are necessary, and protection facilities should be reviewed for long-term conservation and management purposes.
Seo, Junpyo;Eu, Song;Lee, Kihwan;Lee, Changwoo;Woo, Choongshik
Journal of the Society of Disaster Information
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v.17
no.4
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pp.694-709
/
2021
Purpose: In this study, earthquake-induced landslide risk assessment was conducted to provide basic data for efficient and preemptive damage prevention by selecting the erosion control work before the earthquake and the prediction and restoration priorities of the damaged area after the earthquake. Method: The study analyzed the previous studies abroad to examine the evaluation methodology and to derive the evaluation factors, and examine the utilization of the landslide hazard map currently used in Korea. In addition, the earthquake-induced landslide hazard map was also established on a pilot basis based on the fault zone and epicenter of Pohang using seismic attenuation. Result: The earthquake-induced landslide risk assessment study showed that China ranked 44%, Italy 16%, the U.S. 15%, Japan 10%, and Taiwan 8%. As for the evaluation method, the statistical model was the most common at 59%, and the physical model was found at 23%. The factors frequently used in the statistical model were altitude, distance from the fault, gradient, slope aspect, country rock, and topographic curvature. Since Korea's landslide hazard map reflects topography, geology, and forest floor conditions, it has been shown that it is reasonable to evaluate the risk of earthquake-induced landslides using it. As a result of evaluating the risk of landslides based on the fault zone and epicenter in the Pohang area, the risk grade was changed to reflect the impact of the earthquake. Conclusion: It is effective to use the landslide hazard map to evaluate the risk of earthquake-induced landslides at the regional scale. The risk map based on the fault zone is effective when used in the selection of a target site for preventive erosion control work to prevent damage from earthquake-induced landslides. In addition, the risk map based on the epicenter can be used for efficient follow-up management in order to prioritize damage prevention measures, such as to investigate the current status of landslide damage after an earthquake, or to restore the damaged area.
Journal of Korean Society of Disaster and Security
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v.12
no.2
/
pp.73-82
/
2019
Recently, as the occurrence frequency of sudden floods due to climate change increased, the flood damage on riverside social infrastructures was extended so that there has been a threat of overflow. Therefore, a rapid prediction of potential flooding in riverside social infrastructure is necessary for administrators. However, most current flood forecasting models including hydraulic model have limitations which are the high accuracy of numerical results but longer simulation time. To alleviate such limitation, data driven models using artificial neural network have been widely used. However, there is a limitation that the existing models can not consider the time-series parameters. In this study the water surface elevation of the Hangang River bridge was predicted using the NARX model considering the time-series parameter. And the results of the ANN and RNN models are compared with the NARX model to determine the suitability of NARX model. Using the 10-year hydrological data from 2009 to 2018, 70% of the hydrological data were used for learning and 15% was used for testing and evaluation respectively. As a result of predicting the water surface elevation after 3 hours from the Hangang River bridge in 2018, the ANN, RNN and NARX models for RMSE were 0.20 m, 0.11 m, and 0.09 m, respectively, and 0.12 m, 0.06 m, and 0.05 m for MAE, and 1.56 m, 0.55 m and 0.10 m for peak errors respectively. By analyzing the error of the prediction results considering the time-series parameters, the NARX model is most suitable for predicting water surface elevation. This is because the NARX model can learn the trend of the time series data and also can derive the accurate prediction value even in the high water surface elevation prediction by using the hyperbolic tangent and Rectified Linear Unit function as an activation function. However, the NARX model has a limit to generate a vanishing gradient as the sequence length becomes longer. In the future, the accuracy of the water surface elevation prediction will be examined by using the LSTM model.
Journal of Korean Tunnelling and Underground Space Association
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v.16
no.2
/
pp.249-260
/
2014
When a train enters the tunnel at high speed, the pressure wave occurs. When this pressure wave reaches at the exit of tunnel, some are either emitted to the outside or reflected in tunnel by the form of expansion wave. The wave emitted to the outside forms the impulsive pressure wave. This wave is called 'Micro Pressure Wave'. The micro pressure wave generates noise and vibration around a exit portal of tunnel. When it becomes worse, it causes anxiety for residents and damage to windows. Thus, it requires a counterplan and prediction about the micro pressure wave for high speed railway construction. In this paper, the effects of train head nose and tunnel portal shape were investigated by model test, measurement for the micro pressure wave at the operating tunnel as well as numerical analysis for the gradient of pressure wave in the tunnel. As results, a method for predicting the intensity of the micro pressure wave is suggested and then the intensity of the micro pressure wave is analyzed by the tunnel length and the cross-sectional area.
In the case of the enlargement levee on the soft foundation, the existing levee and the enlargement levee connection can be damaged due to heterogeneous subsidence such as differential settlement at the joint of the box culvert passing through the levee. This study selected the downstream region of the Geum River and then confirmed the influence of the piping possibility on the levee by performing a 2D seepage analysis and analyzing the seepage tendency according to the position of the box culvert's gate. As a result, the flow velocity and the hydraulic gradient are larger in the upper breakage than the lower breakage, and the upper leak was more vulnerable to the piping than the lower leak. If leaks occur in the gate located on the riverside land, the risk of piping is increased when the water level rises and is maintained highly. In the case of the gate located on the inland, it could be predicted that the leakage could damage the stability of levee by increasing the water pressure inside the levee. As a result, if leakage occurs at any position in the box culvert, the pore water pressure is increased or decreased compared with the case when no leakage occurs. Therefore, if the pore water pressure is drastically reduced or increased compared with the normal case, leakage may occur. However, the result of this study is based on a 2D seepage analysis, and it is likely to be different from actual cases. Therefore, more detailed analysis by 3D analysis is recommended.
Park, Jong-Sug;Bae, Shin-Chyul;Kim, Young-Min;Paik, Young-Ki;Kim, Ju-Kon;Hwang, Young-Soo
Applied Biological Chemistry
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v.37
no.3
/
pp.148-153
/
1994
Rice black-streaked dwarf virus (RBSDV), a member of the plant reoviridae fijivirus group, causes a serious damage for rice production in Korea. To characterize the RBSDV genome, virus particles were produced by feeding of planthopper (Laodelphax striatellus F.) carring RBSDV to maize plants for 2 days. In $30{\sim}40$ days after feeding, the viral particles were purified from the infected maize roots by using $10{\sim}40%$ sucrose gradient centrifugation. After treatment of 10% SDS to remove the viral coat proteins, ten viral double-stranded RNAs were resolved in agrose gel electrophoresis. Total dsRNA was then used to synthesize cDNA by reverse transcriptase and a cDNA library was constructed in the ${\lambda}gt11$ vector. The phages that contain RBSDV cDNA fragments were selected by hybridizing with the random-primed probe prepared from RBSDV dsRNAs. After subcloning of several cDNA fragments into the pUC19 plasmid vector, one clone (pRV3) was chosen for sequencing. The pRV3 clone was shown to be located on the RBSDV genome fragment No.3 by RNA gel-blot analysis. Sequence analysis of the clone revealed that the pRV3 contains two partial open reading frames.
Objective : This study was undertaker to determine if Juglandis Semen herbal acupuncture (JSA) exerts protective effect against alterations in membrane transport function in rabbits with mercury-induced acute renal failure. Methods : Nephrotoxicity was induced by subcutaneous administration of Hg(a single dose of 10mg/kg) and JSA was performed at both sides of Shenshu($(BL_{23})$, Sinsu) for 7 days. Results: The administration of Hg at a subcutaneous single dose of 10 mg/kg caused a reduction in GFR to 12% of the basal value and an increase in fractional $Na^+$ excretion to 8.9-fold, indicating generation of acute renal failure. When JSA were given for 7 days prior to Hg administration, such changes were significantly attenuated. The fractional excretion of glucose and phosphate was increased to approximately 102- and 35-fold, respectively, in rabbits treated with Hg alone. The increase in rabbits treated with Hg following ISA are significantly lower than that in animals treated with Hg alone. Uptakes of glucose and phosphate in purified isolated brush-border membrane and $Na^+-K^+-ATPase$ activity in microsomal fraction were inhibited in rabbits treated with Hg alone, suggesting that impairment in proximal reabsorption of glucose and phosphate is resulted from a direct damage of membrane transport carriers and disruption of the normal $Na^+$ gradient. Such changes were prevented by JSA. Conclusion These results indicate that the administration of Hg causes impairment in reabsorption of solutes in the proximal tubule via the generation of reactive oxygen species. JSA provides the protection against the Hg-induced impairment in proximal reabsorption, and its effect may be resulted from its antioxidant action.
Frost heave is one of the representative engineering characteristics in cold regions. In South Korea, which is located in seasonal frost area, structural damage caused by frost heave and thaw happens and the need for research on the frost heave is increasing. In this paper, newly developed transparent temperature-controllable cell is used to focus on the frost heave. Frost susceptible artificial soil is used to analyze water intake rate which is one of the important factors in frost susceptibility criteria. Frost heave rate and water intake rate have similar behavior after heave by freezing of pore water converges. O-ring installed in the upper pedestal to measure water intake rate generates side friction between the inner wall of the freezing cell and O-ring, thereby hindering frost heave. Therefore, the frost susceptibility criteria using the water intake rate is not reliable. It is appropriate to use frost heave rate which has similar behavior with water intake rate. Frost heave tests were performed under two different specimen heights. Overburden pressure, temperature gradient and dry unit weight were set under similar state. Based on laboratory testing results, frost heave is independent on the specimen height.
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