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해양생태계 복원기술개발 사업의 경제적 타당성 분석 (Economic Feasibility Analysis of Marine Ecosystem Restoration Technology Program)

  • 권영주;백상규;유승훈
    • 해양환경안전학회지
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    • 제20권2호
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    • pp.130-142
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    • 2014
  • 정부는 훼손된 해양생태계의 현황 및 원인을 파악하고 생태계 기능 복원 및 손실 방지 전략을 수립하기 위해 해양생태계 복원기술개발 사업의 시행을 고려하고 있다. 사업 시행 여부에 대한 판단을 위해서는 이 사업에 대한 경제적 타당성 분석이 필수적으로 요구된다. 이에 본 연구에서는 조건부 가치측정법(CVM, contingent valuation method)을 적용하여 사업 수행의 경제적 타당성을 분석하고자 한다. 지불의사 유도방법으로 유인일치적인 양분선택형 모형을 이용하되, 지불의사액 추정모형으로 영(0)의 응답을 명시적으로 다룰 수 있는 스파이크 모형을 적용한다. CVM 적용을 위한 설문조사는 미국 해양대기청의 지침에 따라 전국 1,000가구를 대상으로 일대일 개별면접을 통해 2013년에 시행되었다. 분석결과 연간 가구당 평균 지불의사액은 5,414원으로 추정되었다. 이 값을 전국으로 확장하면 향후 5년 동안 연간 약 986억원에 달한다. 이 값과 해양생태계 복원기술개발 사업의 투자비 정보를 이용하여 경제성을 분석한 결과, 순현재가치, 편익/비용 비율, 내부수익률은 각각 3,378억원, 5.20, 65.9 %로 산정되어 각각 0, 1.0, 5.5 %를 상회하므로 이 사업은 비용-편익 분석을 통과한다.

한의학의 항종양 면역치료에 관한 연구 -1990년 이후 발표된 실험논문을 중심으로- (Compilation of 104 Experimental Theses on the Antitumor and Immuno-activating therapies of Oriental Medicine)

  • 강연이;김태임;박종오;김성훈;박종대;김동희
    • 동의생리병리학회지
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    • 제17권1호
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    • pp.1-24
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    • 2003
  • This study was done to compile 104 experimental theses which are related to the antitumor and immuno-activating therapies between February 1990 through February 2002. Master's and doctoral theses were dassified by schools, degrees, materials, effects, experimental methods of antitumor and immunoactivity, and results. The following results were obtained from this study : 1. Classifying the theses by the school, 34.6% were presented by Daejeon University, 29.8% by Kyung-hee University and 11.5% by Won-kwang University. Of all theses, 51.0% were aimed for the doctoral degree and 43.3% were for the master's degree. All of three universities have their own cancer centers. 2. Classifying the theses by herb materials, complex prescription accounted for 60.3%, single herb accounted for 24.8% and herbal acupuncture accounted for 14.2%. Considering the key principles of the traditional medicine, complex prescription was much more thoroughly studied than single herb prescription. The results showed that the complex prescription had both antitumor activity and immuno-activating activity, which might reflects on multi-activation mechanisms by complex components. 3. Classifying the theses by the efficacy of herbs examined, in single herb, invigorating spleen and supplementing was 35.5%, expelling toxin and cooling was 29.0%, activating blood flow and removing blood stasis was 12.9%. In herbal acupuncture, invigorating spleen and supplementing was 52.9%, expelling toxin and cooling was 29.4%. In complex prescription, pathogen-free status was 41.9%, strengthening healthy qi to eliminate pathogen was 35.5%, strengthening healthy qi was 22.6%. It is presumed that the antitumor and immunoactivating therapy based on syndrome differentiation is the best way to develop oriental oncology. 4. Classifying the theses by antitumor experiments, cytotoxic effect was 48.1 %, survival time was 48.1 % and change of tumor size was 42.3%. Survival rate was not necessarily correlated with cytotoxicity. These data reflect the characteristic, wholistic nature of the oriental medicine which is based on BRM (biological response modifier). 5. Classifying the theses by immunoactivating experiments, hemolysin titer was 51.0%, hemagglutinin titer was 46.2% and NK cell's activity was 44.2%. In the future studies, an effort to elucidate specific molecular and cellular mechanisms of cytokine production in the body would be crucial. 6. Classifying the theses according to the data in terms of antitumor activity, 50% was evaluated good, 24.0% was excellent, and 15.5% have no effect. In an evaluation of immuno-activating activity, 35.9% was excellent and 18.0% showed a little effect. The index point, as described here, may helps to use experimental data for clinical trials. Changes in index points by varying dosage implicate the importance of oriental medical theory for prescription. 7. In 167 materials, IIP (immunoactivating index point, mean : 3.12±0.07) was significantly higher than AIP(antitumor index point, mean : 2.83±0.07). These data demonstrate that the effect of herb medicine on tumor activity depends more on immunoactivating activity than antitumor activity. This further implies that the development of herbal antitumor drugs must be preceded by the mechanistic understanding of immunoactivating effect. 8. After medline-searching tumor and herb-related articles from NCBI web site, we conclude that most of the studies are primarily focused on biomolecular mechanisms and/or pathways. Henceforth, we need to define the biomolecular mechanisms and/or pathways affected by herbs or complicated prescriptions. 9. Therefore, the most important point of oriental medical oncology is to conned between experimental results and clinical trials. For the public application of herbal therapy to cancer, it is critical to present the data to mass media. 10. To develop the relationship of experimental results and clinical trials, university's cancer clinic must have a long-range plan related to the university laboratories and, at the same time, a regular consortium for this relationship is imperative. 11. After all these efforts, a new type herbal medicine for cancer therapy which is to take care of the long-term administering and safety problem must be developed. Then, it would be expected that anti-tumor herbal acupuncture can improve clinical symptoms and quality of life (QOL) for cancer patients. 12. Finally, oriental medical cancer center must be constructed in NCC (National Cancer Center) or government agency for the development of oriental medical oncology which has international competitive power.

의료법에 의거한 의료기관 종별 간호사 정원기준 충족률 추이 분석 (Nurse Staffing Levels and Proportion of Hospitals and Clinics Meeting the Legal Standard for Nurse Staffing for 1996~2013)

  • 조성현;이지윤;전경자;홍경진;김윤미
    • 간호행정학회지
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    • 제22권3호
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    • pp.209-219
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    • 2016
  • Purpose: To analyze the proportion of medical institutions meeting the legal standard for nurse staffing. Methods: Data collected from 29,282 institutions between 1996 and 2013 were analyzed. Nurse staffing was measured as daily patient census per registered nurse (RN). The standard for general hospitals, hospitals, and clinics is 2.5 or less, and that for long-term care hospitals is 6.0 or less of the daily patient census per RN. Clinics may substitute nursing assistants for RNs by 50% or 100% depending on their daily inpatient census; long-term care hospitals may substitute nursing assistants for RNs by two thirds of the required number of RNs. Results: The proportion of general hospitals, hospitals, clinics, and long-term care hospitals meeting the standards was 63%, 19%, 63%, and 94%, respectively, in 2013. While general hospitals had an increase in the proportion during the 1996-2013 period, small changes were found in hospitals and clinics. In 2013, nurses were estimated to care for 16 (interquartile range: 12~24) patients per shift in general hospitals. Three quarters of clinics had no RNs in 2013. Conclusion: Many medical institutions did not meet the legally mandated minimum staffing level. The government must implement policy actions for all medical institutions to meet the legal standards.

사업장 보건관리자 공동채용모형개발(II)-사업주와 간호사의 의견 비교- (Developing the Joint Employment System of Occupational Health Nurse Practitioners for the Minor Enterprises in Korea (Part 2) - Comparison of Opinions between Employers and Occupational Health Nurses -)

  • 김영임;전경자;이성은;윤순녕
    • 지역사회간호학회지
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    • 제9권2호
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    • pp.313-323
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    • 1998
  • This study is to develop the model on the joint employment system of occupational health nurse practitioners for medium or small sized enterprises in Korea based on the comparison opinions between employers and occupational health nurses (OHN). The data were collected by questionnaires from Oct. to Nov. in 1997. The number of subjects was 210 OHNs and 176 employers, response rate was 47.1% for OHNs and 23.2% for employers. The SAS PC program was used for the descriptive statistics. The results were as follow: 1. More than three years career was preferred for qualification of OHN by employers and OHNs. OHNs preferred that all instruments and materials should be equipped in each industry, but employers preferred that they should be equipped by OHN. 2. For the limit number of industries and employees per one OHN, employers preferred average 2.25 industries and 307 employees, OHNs preferred average 3.0 industries and 448 employees. Both of them preferred two times visit per week for all day long. 3. OHNs wanted that the local office of Ministry of Labor could act as mediator, but employers preferred direct contact individually. For the average wage, employers preferred 887,000 won per month, but OHNs preferred 1,960,000 won per month. 4. OHNs preferred the Korean Association of Occupational Health Nurse as the recruit agency. Finally, employers and OHNs have the opinions that they can choose this system depending on the condition. There is in need of development of effective strategy for this new system such as manpower development, cost-benefit analysis, establishment of occupational health service standard, advertisement for employers, and government supported project.

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요양기관별 한국노인의 기능상태와 장기요양등급 비교 (The Comparison of Functional Status and the Level of Health Care Needs in Elderly Koreans in Health Care Institutions)

  • 김현실;정영미;이홍자;조유향;유인영
    • 지역사회간호학회지
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    • 제21권4호
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    • pp.386-397
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    • 2010
  • Purpose: The purpose of this study was to compare functional status and the level of health care needs in elderly Koreans in health care institutions. Methods: Data were collected from 2,521 elderly patients admitted in 50 health care institutions (hospitals, oriental hospitals, geriatric hospitals, and health care facilities) selected through proportional stratified sampling in 2008. We used a long-term care (LTC) assessment tool developed by the government, which consists of 52 items with 5 subscales. Results: Statistically significant differences were detected in functional status and the level of health care needs among the subjects in different health care institutions. Of the sample population in geriatric hospitals, 48.9% were eligible for LTC Category 1, 20.9% for Category 2, and 17.2% for Category 3, and 13.1% of the subjects were not eligible for any of the categories. Of the sample population in health care facilities, 29.9% were eligible for LTC Category 1, 20.5% for Category 2, and 21.8% for Category 3, and 27.0% of the subjects were not eligible for any of the categories. Conclusion: The findings of this study indicate the necessity of the development of an evaluation system that helps determine whether a subject is eligible for LTC.

Reevaluation of bactericidal, cytotoxic, and macrophage-stimulating activities of commercially available Fucus vesiculosus fucoidan

  • Nishiguchi, Tomoki;Jiang, Zedong;Ueno, Mikinori;Takeshita, Satoshi;Cho, Kichul;Roh, Seong Woon;Kang, Kyong-Hwa;Yamaguchi, Kenichi;Kim, Daekyung;Oda, Tatsuya
    • ALGAE
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    • 제29권3호
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    • pp.237-247
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    • 2014
  • Polysaccharides prepared from marine algae sometimes contain contaminants such as polyphenols and endotoxins that may mislead their bona fide biological activities. In this study, we examined bioactive contaminants in commercially available fucoindan from Fucus vesiculosus, along with ascophyllan and fucoidan from Ascophyllum nodosum. F. vesiculosus fucoidan inhibited the growth of Vibrio alginolyticus in a concentration-dependent manner ($0-1,000{\mu}g\;mL^{-1}$). However, the antibacterial activity of the fucoidan significantly reduced after methanol-extraction, and the methanol-extract showed a potent antibacterial activity. The extract also showed cytotoxicity to RAW264.7 and U937 cells, and induced apoptotic nuclear morphological changes in U937 cells. These results suggest that the antibacterial activity of the fucoidan is partly due to the methanol-extractable contaminants that can also contribute to the cytotoxicity on RAW264.7 and U937 cells. On the other hand, the activities to induce secretion of nitric oxide and tumor necrosis factor-${\alpha}$ from RAW264.7 cells were observed in the fucoidan even after methanol extraction, and the extract had no such activities. Our observations suggest that commercially available fucoidan should be purified prior to biochemical use.

성교육 프로그램이 초등학교 5학년 학생의 성 관련 지식 및 태도에 미치는 효과 (The Effects of a Sex Education Program on Sex-related Knowledge and Attitude of 5th-Grade Elementary School Students)

  • 이관순;이정숙
    • 한국학교보건학회지
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    • 제17권1호
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    • pp.25-39
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    • 2004
  • The purpose of this study is to examine the effect of the sex education program on the elementary school students' sex-related knowledge and attitude. The research method used in this study is an equivalent control group pre-test and post-test and post-test design in a quasi-experimental research format. The subjects of this study were the 5th-grade elementary school students(63 in the experimental group and 60 in the control group) in O and O elementary school in G city. The data was collected from April 4th to July 3th, 2003. The experimental group received a sex education program while the control group did not receive any treatment. The sex education program was implemented for 40 minutes every 2-3 days which total twelve sessions over 4 weeks. Using the SPSS 10.0 program, the data was analyzed by $X^2$ - test, Fisher exact test, t-test, and a repeated measures ANOVA., Rrsults : The experimental group who received the sex education program showed a significantly higher sex-related knowledge score than the control group (F=140.52, p=.001). The experimental group showed a significantly higher sex relatied attitudes score than the control group (F=40.80, p=.001). This study concluded that the sex education program was effective in both sex-related knowledge and attitudes for elementary school students. Therefore, it appears to be effective for 5th-grade students to receive intensive sex education. It es recommended that the schools and government develop education media and a sex education program for parents, have a sex education teacher and a place where students can be counseled, and a professional consultant who can effectively counsel the students regarding sex-related issues.

농촌마을 가꾸기 경진대회 참여 마을의 농촌관광 성과분석 -도시민 유치실적과 소득 및 고유 축제를 중심으로- (A Study of Performance of Rural Tourism in the Participating Village to Rural Village Contest - With Special Reference on Urban Visitors and Income, Original Festival of Village -)

  • 박재철;송광인;박천창;김현욱;심재건;이기봉
    • 농촌계획
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    • 제12권3호
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    • pp.107-115
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    • 2006
  • The purpose of this study was to document a phenomenon of rural tourism in Korea by Investigating characteristics of 50 villages that had participated in a competition of 'stimulation of rural village' The results are as follows: 1) The degrees of activation of rural tourism varied according to marketing efforts made by individual provincial(local) government. The results of contest indicated that provinces such as Gangwon-do, Chungnam-do, and Gyunggi-do showed highest performance among other competing local governments; 2) The results revealed that the total profit generated from direct sale of farm products outnumbered profits gained from sales of lodging and foods. This indicated that there is a room for improvement with respect to boosting more sales on lodging and food; 3) The regression analysis indicated a significant relationship between profits earned from sales of experiential tourism product and those from direct sale of farm products(multi-correlation coefficient: 0.38); 4) It was identified that Gyunggi and Ganwon provinces were ranked first in sales of foods and those of lodging, respectively; 5) Finally, it was showed that among the 50 participating villages, only 16 ones hold festivals by means of attracting tourists from outside.

보건진료소 가족계획 및 모자보건사업(1980년~2009년) (Family Planning and Maternal-Child Health Services that Disciplined Itself in Primary Health Care Post from 1980 to 2009)

  • 손계순
    • 한국농촌간호학회지
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    • 제3권2호
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    • pp.104-115
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    • 2008
  • Purpose: A study of the family planning and Maternal-Child Health Services that disciplined itself in primary health care post form 1980 to 2009. Method: Investigation studies family planning in primary health care post and a change process of a Maternal-Child Health Services into case by case until 2009 from 1980. Results: Our country family planning business began at economic development dimensions in order to solve a poverty issue. This business goal were childbirth decrease of pregnancy possibility couple aged 19~49 and improve to mother and child health. For this goal, all kinds of health education included sex education and contraception education, contraception service, comprehensive maternal and child health service that management of front and back of childbirth etc. are provided. According to fail down a birthrate from 6.0(1962) to 1.25(2009), the nation reached to a dilemma called childbirth encouragement policy. Conclusions: Decrease of labor supply by low birthrate, decrease numerical an employed person by aging was brought a labor shortage and decrease of productivity of labor of industrial manpower. Deterioration phenomenon of financial income and expenditure by consumption and investment contraction caused decrease of slowdown of economic growth and potential growth rate, and a social cost burden is increased by deterioration financial old man support burden increase by this and pensions and health insurance, a sharp increase of social welfare cost etc. Now, in order to solve a low birth issue, the government establishes a whole nation forwarding system and establishes basic plan social low birth and advanced age, and to prepare for childbirth fault factors removal and advanced age society shall endeavor.

전북지역 복분자와 오디 음료 제품의 구매실태 및 제품 속성의 중요도와 만족도 비교 (A Study on the Consumption Patterns, the Importance of Product Properties, and the Satisfaction Levels of Blackberry and Mulberry Fruit Beverage Products in the Jeonbuk Area)

  • 양향숙;노정옥
    • 대한가정학회지
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    • 제49권10호
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    • pp.29-37
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    • 2011
  • The principal objective of this study was to evaluate the consumption patterns, the importance of product properties, and the satisfaction levels of blackberry and mulberry fruit beverage products(BMBPs) in the Jeonbuk area, Korea. Self-administered questionnaires were collected from 294 customers(male 40.8%, female 59.2%) residing at Jeonju in Jeonbuk area. Descriptive and comparative statistical analyses were completed using SPSS PC program(version 19.0). Approximately, 61.6% of participants consumed BMBPs 1-2times a year. Only 1.7% of participants consumed BMBPs everyday. The main information source about BMBPs was 'families/friends'. About 58.8% of participants responded that the main reason for purchasing BMBPs was 'for health'. The result indicated the overall importance level(3.94) was higher than the satisfaction level(3.41)(p < .001). The importance and satisfaction levels of the older group (50's) were significantly higher than the levels of younger group(20-30's)(p < .01 ; p < .05). According to the IPA(Importance-Performance Anslysis), 'price' and 'credibility' of companies were the most important properties that had to be changed as soon as possible to increase satisfaction with BMBPs. Therefore, to increase BMBPs'-consumption, quality improvements on these products through cooperation between BMBPscompanies, the regional government, and research institutions are necessary.