• Title/Summary/Keyword: generic data

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Current and future Statistical Consideration in Bioequivalence Trials

  • Park, Sang-Gue
    • 한국데이터정보과학회:학술대회논문집
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    • 2006.11a
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    • pp.43-48
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    • 2006
  • In 2001 US FDA proposed a draft guidance for future in vivo bioequivalence studies. The guidance suggested specific criteria for new drug sponsors to show prescribability and switchability in bioequivalence testing for approval of generic drugs. However, there is less acceptance of the need to change statistical procedures and study designs from those currently used to assess the current criterion of average bioequivalence. The measures of population and individual bioequivalence testing are introduced and statistical procedures for them are discussed.

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Implementation Scheme of Database System for Reliability Prediction of the Mechanical System (기계류 시스템 신뢰성 예측 데이터베이스 시스템 구축 방안)

  • Kim, Yon-Soo
    • Journal of Applied Reliability
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    • v.5 no.4
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    • pp.451-463
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    • 2005
  • This paper describes procedure to build a generic reliability analysis database structure and failure data during the conceptual design phase. Reliability prediction utilizing such supporting database system enable the designer to quantify the effects of varying design and operational constrains on mechanical component's failure rate. This leads to compare competing alternatives to the reliability improvement efforts.

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STABILITY OF FUZZY DYNAMIC CONTROL SYSTEM: The Cell-State Transition Method

  • Kang, Hoon
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1993.06a
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    • pp.1078-1081
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    • 1993
  • The Objective of this paper is to provide fuzzy control designers with a design tool for stable fuzzy logic controllers. Given multiple sets of data disturbed by vagueness uncertainty, we generate the implicative rules that guarantee stability and robustness of closed-loop fuzzy dynamic systems. We propose the cell-state transition method which utilizes Hsu's cell-to-cell mapping concept [1]. As a result, a generic and implementable design methodology for obtaining a fuzzy feedback gain K, a fuzzy hypercube [2], is provided and illustrated with simple examples.

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Crystal Geometry Optimization of β-Lactam Antibiotics Using MMFF Parameters

  • 원영도
    • Bulletin of the Korean Chemical Society
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    • v.16 no.10
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    • pp.944-952
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    • 1995
  • A generic force field approach has been applied to geometry optimization of penam and cephem crystals. The crystalline state energy and force evaluation with the universal force field (MMFF: Merck Molecular Force Field) results in good agreements with the crystallographic data. Bond lengths are usually correct to within 0.02 Å and bond angles usually to within 2.5°. The conformation of the β-lactam bicyclic rings in the crystal environment is also well reproduced. The results thus demonstrate the applicability of MMFF to modeling of newer molecular constructs in condensed phase.

Experimental characterization of a smart material via DIC

  • Casciati, Sara;Bortoluzzi, Daniele;Faravelli, Lucia;Rosadini, Luca
    • Smart Structures and Systems
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    • v.30 no.3
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    • pp.255-261
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    • 2022
  • When no extensometer is available in a generic tensile-compression test carried out by a universal testing machine (for instance the model BIONIX from Material Testing Systems (MTS)), the test results only provide the relative displacement between the machine grips. The test does not provide any information on the local behaviour of the material. This contribution presents the potential of an application of Digital Image Correlation (DIC) toward the reconstruction of the behaviour along the specimen. In particular, the authors test a Ni-Ti shape memory alloys (SMA) specimen with emphasis on the coupling of the two measurement techniques.

A Design of Web based GEM Using Single Object Access Protocol

  • Kang W. Joon;Park, H. Seong
    • 제어로봇시스템학회:학술대회논문집
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    • 2001.10a
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    • pp.57.5-57
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    • 2001
  • This paper presents an enhanced web-based distributed system with Single Access Object Protocol(SOAP), which uses HTTP as a communication protocol and XML as a data presentation. The suggested system is applied into a Generic Equipment Model (GEM) for exchanging specified messages(SECS-II), which are encoded into XML presentation, between Equipment and Host via the web sorrel. In this paper, the designed system architecture and its soap components are presented.

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Design and Implementation of A Video Information Management System for Digital Libraries (디지털 도서관을 위한 동영상 정보 관리 시스템의 설계 및 구현)

  • 김현주;권재길;정재희;김인홍;강현석;배종민
    • Journal of Korea Multimedia Society
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    • v.1 no.2
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    • pp.131-141
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    • 1998
  • Video data occurred in multimedia documents consist of a large scale of irregular data including audio-visual, spatial-temporal, and semantic information. In general, it is difficult to grasp the exact meaning of such a video information because video data apparently consist of unmeaningful symbols and numerics. In order to relieve these difficulties, it is necessary to develop an integrated manager for complex structures of video data and provide users of video digital libraries with easy, systematic access mechanisms to video informations. This paper proposes a generic integrated video information model(GIVIM) based on an extended Dublin Core metadata system to effectively store and retrieve video documents in digital libraries. The GIVIM is an integrated mo이 of a video metadata model(VMN) and a video architecture information model(VAIM). We also present design and implementation results of a video document management system(VDMS) based on the GIVIM.

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Automated Design of Viterbi Decoder using Specification Parameters (사양변수를 이용한 비터비 복호기의 자동설계)

  • Kong, Myoung-Seok;Bae, Sung-Il;Kim, Jae-Seok
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.36C no.1
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    • pp.1-11
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    • 1999
  • In this paper, we proposed a design method of parameterized viterbi decoder, which automatically synthsizes the diverse viterbi deciders used in the digital mobile communication systems. It is designed to synthesize a viterbi decoder specified by user-provided parameters. Those parameters are constraint length, code rate generator polynomials of teh convolutional encoder, data rate and bits/frame of the data transmission, and soft decision bits of viterbi decoder. For the design of the parameterized viterbi decoder, we designed a user interface module C-language, and a viterbi decoder module in a hierarchical atructure using VHDL language and its generic statement. For the verification of the parameterized viterbi decoder, we compared our synthesized viterbi decoder with the conventional viterbi decoder which is designed for the IS-95 CDMA system. The proposed design method of the viterbi decoder will be a new method to obtain a required viterbi decoder in a very short time only by supplying the design parameters.

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Development of the Cross-vertical Ontology for Context Aware Service in Various IoT Environment (다양한 IoT 환경에서 상황인지 서비스 제공을 위한 크로스 버티컬 온톨로지 개발)

  • Yang, Nari;Choi, Hoan-Suk;Rhee, Woo-Seop
    • The Journal of the Korea Contents Association
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    • v.15 no.2
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    • pp.58-73
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    • 2015
  • In the IoT environment, context information is important to provide context service to the user. For this, collected data from devices such as sensors or actuators, converts to context information using the ontology. Because the existing ontologies designed for target service, if the user wants to change the service requirements, service condition, service environment or another service, overall ontology will be redesigned to the changed service. To overcome this difficulty, we propose the cross-vertical ontology model called the Generic Ontology Models(GOMs). It can define the user's desired services without regarding to place and situation. Also, we propose IoT service concept model that represents data flow of the IoT service and IoT service environment. Moreover, as the use case, we show that the proposed GOMs are able to provide the IoT service well.

Development of User-friendly Modeling Interface for Process-based Total System Performance Assessment Framework (APro) for Geological Disposal System of High-level Radioactive Waste (고준위폐기물 심층처분시스템에 대한 프로세스 기반 종합성능평가 체계(APro)의 사용자 친화적 모델링 인터페이스 개발)

  • Kim, Jung-Woo;Lee, Jaewon;Cho, Dong-Keun
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.17 no.2
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    • pp.227-234
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    • 2019
  • A user-friendly modeling interface is developed for a process-based total system performance assessment framework (APro) specialized for a generic geological disposal system for high-level radioactive waste. The APro modeling interface is constructed using MATLAB, and the operator splitting scheme is used to combine COMSOL for simulation of multiphysics and PHREEQC for the calculation of geochemical reactions. As APro limits the modeling domain to the generic disposal system, the degree of freedom of the model is low. In contrast, the user-friendliness of the model is improved. Thermal, hydraulic, mechanical and chemical processes considered in the disposal system are modularized, and users can select one of multiple modules: "Default process" and multi "Alternative process". APro mainly consists of an input data part and calculation execution part. The input data are prepared in a single EXCEL file with a given format, and the calculation part is coded using MATLAB. The final results of the calculation are created as an independent COMSOL file for further analysis.