• Journal of the Korean Society of Radiology
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• v.79 no.5
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• pp.286-289
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• 2018

Toxocariasis, a parasitic infection, causes hyper eosinophilia resulting in radiological presentation of eosinophilic infiltrations in the involved organs. In the abdomen, toxocariasis has been reported to manifest as infiltrations in the liver or in the gastrointestinal tract, but it is known to be uncommon to manifest as multiple lymphadenopathy. There have been two case reports of toxocariasis presenting as generalized lymphadenopathy in the chest, neck and inguinal regions. To the best of our knowledge, generalized conglomerated lymphadenopathy occurring mostly in the abdomen from toxocariasis has not been published in the English literature. Herein, we report a rare case of toxocariasis presenting as multiple conglomerated lymphadenopathy mimicking lymphoma on CT.

• Journal of Veterinary Clinics
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• v.39 no.5
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• pp.235-239
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• 2022

A 10-year-old neutered male Siberian Husky presented with paraparesis and severe lethargy. On physical examination, the patient was unable to weight-bear and walk and exhibited significant muscle mass loss in both hindlimbs and generalized truncal alopecia with a dull coat of hair. On neurological examination, cranial lumbar vertebral pain, hind limb cross-extensor reflex, delayed hindlimb postural reaction, upper motor neuron bladder dysfunction, and total absence of cutaneous trunci reflex were identified. Computed tomography revealed diffuse idiopathic skeletal hyperostosis and spondylosis deformans of the cervical and thoracolumbar vertebrae. In addition, a generalized decrease in bone mineral density of the vertebrae was identified. Magnetic resonance imaging showed hyperplasia of the epidural fat compressing the spinal cord in the thoracolumbar region and concurrent mild multiple intervertebral disc herniations. No specific findings were observed in cerebrospinal fluid analysis. Blood analysis of thyroid function revealed decreased total T4 and free T4 levels, and increased TSH levels. The patient was tentatively diagnosed with spinal epidural lipomatosis (SEL) secondary to hypothyroidism. The patient was treated with levothyroxine, firocoxib, and gabapentin. Clinical signs gradually improved, and the patient showed normal ambulation 40 days after treatment initiation. SEL is extremely rare in dogs. To the best of our knowledge, this is the first case report of SEL secondary to hypothyroidism that was treated conservatively. Secondary SEL can be sufficiently managed by treating the underlying cause, if possible.

• Journal of Genetic Medicine
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• v.21 no.1
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• pp.31-35
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• 2024

Allan-Herndon-Dudley syndrome (AHDS) is a rare X-linked neurodevelopmental disorder with abnormal thyroid function caused by mutation in the solute carrier family 16 member 2 (SLC16A2) gene. Clinical manifestations of AHDS are global or axial hypotonia, a variety of movement disorders, severe intellectual disability, quadriplegia or spastic diplegia, growth failure, and seizures. A 10-year-old boy visited our hospital with the chief complaint of newly onset generalized tonic seizures with vocalization of weekly to daily frequency. He showed early infantile hypotonia, severe intellectual disability, and frequent respiratory infections. He could not walk independently and was non-verbal. Electroencephalogram revealed generalized slow spike and waves with multifocal spikes and slow background rhythms. His tonic seizures were controlled with more than two anti-seizure medications (ASMs). At 11 years of age, he was evaluated for thyroid function as part of regular screening for ASM maintenance and was found to have abnormal thyroid function. We performed whole exome sequencing for severe global developmental delay, drug-resistant epilepsy, and abnormal thyroid function. The hemizygous c.940C>T (p.Arg314Ter) variant in the SLC16A2 gene (NM_006517.5) was identified and confirmed based on Sanger sequencing. Herein, we describe a case of an AHDS patient with late-onset drug-resistant epilepsy combined with congenital hypotonia, global developmental delay, and abnormal thyroid function results. To the best of our knowledge, this is the oldest adolescent among AHDS cases reported in Korea. In this report, clinical characteristics of a mid-adolescence patient with AHDS were presented.

• Knowledge Management Research
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• v.23 no.3
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• pp.129-152
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• 2022

As a key infrastructure for digital transformation, the spread of data, network, artificial intelligence (D.N.A.) fields and the emergence of promising industries are laying the groundwork for active digital innovation throughout the economy. In this study, by applying the text mining methodology, major topics were derived by using the abstract, publication year, and research field of the study corresponding to the SCIE, SSCI, and A&HCI indexes of the WoS database as input variables. First, main keywords were identified through TF and TF-IDF analysis based on word appearance frequency, and then topic modeling was performed using g-DMR. With the advantage of the topic model that can utilize various types of variables as meta information, it was possible to properly explore the meaning beyond simply deriving a topic. According to the analysis results, topics such as business intelligence, manufacturing production systems, service value creation, telemedicine, and digital education were identified as major research topics in digital transformation. To summarize the results of topic modeling, 1) research on business intelligence has been actively conducted in all areas after COVID-19, and 2) issues such as intelligent manufacturing solutions and metaverses have emerged in the manufacturing field. It has been confirmed that the topic of production systems is receiving attention once again. Finally, 3) Although the topic itself can be viewed separately in terms of technology and service, it was found that it is undesirable to interpret it separately because a number of studies comprehensively deal with various services applied by combining the relevant technologies.

• Women's Health Nursing
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• v.3 no.1
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• pp.39-50
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• 1997

To examine the effects of an educational program with a purpose of reducing symptoms and ailments of women's premenstrual syndrome on the basis of the Self-care theory of Orem, a stimulation was carried out by using pre-and post-design of non-equity control group after choosing both an experimental group of 62 persons and a control group of 62 persons among 497 industrial women. This study was conducted from June 20, 1996 to September 30, 1996. Meantime, an education was provided for the experimental group of 62 persons for 8 weeks but no education for the control group of 62 persons. Study matters are general and obstetric characteristics, knowledge and self-care behavior and premenstrual syndrome from questionnaires with 497 industrial women, pre and post questionnaires with the control group of 62 persons and the questionnaires collected before and after providing an education for the experimental group of 62 persons, these matters were used as research data for this study and analyzed by means of the SAS program. As a result, it was shown that the scores of 497 industrial women's knowledge by age were the highest 26.36 for 20 to 29 year old women, then 25.58 for 30 to 39 year old women and 25.74 for less 19 year old women. The performance scores of their self-care behavior by age were the highest 39.17 for 30 to 39 year old women, 35.72 for 20 to 29 year old women and 32.85 for less 19 year old women, which means that the older the women are, the higher the performance degree is(p<0.01). And the scores of their premenstrual syndrome by age were 2.80 for less 19 year old women, 2.18 for 20 to 29 year old women and 2.00 for 30 to 39 year old women. Women in their teens and twenties showed more serious symptoms and ailments of premenstrual syndrome than women in their thirties(p<0.01). For the experimental group of 62 persons who received the educational program, both the knowledge of premenstrual syndrome and the degree of self-care behavior were remarkably improved(p<0.01), respectively and the symptoms and ailments of premenstrual syndrome were also remarkably reduced(p<0.01), while the control group showed no change in the knowledge, self-care behavior, and symptoms and ailments of premenstrual syndrome. The above results demonstrated that educational program based on the Self-care theory of Orem is an effective intervention to reduce the symptoms and ailments of premenstrual syndrome. The effects of the study can be generalized by extending the application in which various age groups and professional and social environments are considered together with a research to evaluate the long-term effects of this educational program. Accordingly, it is expected that it can possible not only to provide help for the women by actually applying the program to practical areas for improvement of women's health but also to suggest plans to activate it as one of health education areas.

• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.3
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• pp.321-339
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• 2014

This paper concerns the development of a knowledge-based tunnel design system within the framework of artifical neural networks(ANNs). The system is aimed at expediting a routine tunnel design works such as computation of segment lining body forces and stability analysis of selected cross section. A number of sub-modules for computation of segment lining body forces and stability analysis were developed and implemented to the system. It is shown that the ANNs trained with the results of 3D numerical analyses can be generalized with a reasonable accuracy, and that the ANN based tunnel design concept is a robust tool for tunnel design optimization. The details of the system architecture and the ANNs development are discussed in this paper.

• Journal of the Korean Society for Library and Information Science
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• v.38 no.1
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• pp.281-301
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• 2004

The national investment versus research result management ratio is very low as we compare to those of other advanced countries. Also the system of efficient usage of research result is insufficient. It results inefficient R＆D investment when we drive national R＆D programs. In this paper we developed a generalized information system for efficient planning and management of national R＆D programs. And we developed a efficient system of the R＆D information support and a system of a smoothly circulating R＆D information. Also we apply those systems to the development of the information system of Korea Research Council of Fundamental science and technology. This application system can provide a total R＆D information of whole life cycle of the national R＆D programs.

• Journal of Korean Medical classics
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• v.31 no.1
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• pp.57-78
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• 2018

Objectives : The paper uses recitation test, one of the study and evaluation methods in the Korean Medical Classics, to provide a basis upon which thoughts can be given to the education of Korean Medicine, and furthermore the essence of education itself. Methods : 1. The paper reviewed how recitation tests were performed in Goryeo and Joseon. 2. The paper introduces the methods of applying recitation test to the education of the Korean Medical Classics and their results. The paper furthermore discussed possible improvements. 3. The paper pondered on the traditional aspects of the significances (principles) of recitation tests and their cognitive neuroscience aspects. Results : 1. The imperial examinations for medical officers during Goryeo and Joseon both performed recitation tests, and the subject of these tests were given more weight than other subjects. 2. Recitation test is a form of education that revolves around the learners. It requires a detailed plan of execution for it to be effective. 3. The significances (principles) of recitation test are reviewed from the aspect of cognitive neuroscience, and the deductions from the traditional aspects are made into "conceptual abstract, come to things & run out knowledge, and flash back." Conclusions : Recitation test was the humanity's way of conserving and conveying knowledge & wisdom from the times before the invention of letters. This method is the oldest education method of acquiring concepts that are generalized and made abstract through indirect experiences. This method is still effective today. In the education of the Korean Medical Classics, this method was used to supplement the public education method and create an education method that revolves around individual learner in a way that utilizes the strengths of education in apprenticeship.

• International Commerce and Information Review
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• v.9 no.2
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• pp.103-120
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• 2007

The knowledge based economy requires more and more people to learn new knowledge and skills in a timely and effective manner. These needs and new technology such as computer and Internet are fueling a transition in e-learning. According to specialist's opinion, imagination experience studying is generalized, and learning environment that language barrier by studying, multi-language studying Machine that experience past things that disappear through simulation, and travel area, and experience future changed state disappears is forecasting to come. This is previewing finally that it may become future education that education and IT, element of entertainment is combined. Already, became story that argument for party satellite of e-Learning existence passes one season already. e-Learning is utilized already in all educations that we touch by effectiveness by corporation's competitive power improvement and implement of lifelong education in educational institutions through present e-Learning. It is obvious that when see from our viewpoint which is defining e-Learning by one industry and rear by application to education as well as one new growth power about these, e-Learning industry becomes very important means that can solve dilemma of growth real form. Only, special quality of digital industry that e-Learning is being same with other digital industry and repeat putting out a fire rapidly, and is repeating sudden change that these evolution is not gradual growth of accumulation and improvement of technology that is appearing consider need to. In the meantime, we need to observe about evolution of Information Technology. Because there is some scholars who e-Learning's concept foresees to evolve by u-Learning.(although, a person who see that these concept is not more in marketing terminology by some scholars' opinion is). This u-Learning's concept means e-Learning that take advantage of ubiquitous technology as Ubiquitous-Learning's curtailment speech. Ubiquitous, user means Information-Communication surrounding that can connect to network freely regardless of place without feeling network or computer. There is controversy about introduction time regarding these direction, but e-Learning is judged to evolve by u-Learning necessarily. Because keep in step and age that study all contents that learner wants under environment of 3A (any time, any whrer, any device) by individual order thoroughly is foreseen to come in ubiquitous learning environment that approach more festinately.

• The KIPS Transactions:PartB
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• v.12B no.4 s.100
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• pp.479-486
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• 2005

The ontology was proposed to construct the logical basis of semantic web. Ontology represents domain knowledge in the formal form and it enables that machine understand domain knowledge and provide appropriate intelligent service for user request. However, the construction and the maintenance of ontology requires large amount of cost and human efforts. This paper proposes an automatic ontology construction method for defining relation between concepts in the documents. The Proposed method works as following steps. First we find concept pairs which compose association rule based on the concepts in domain specific documents. Next, we find pattern that describes the relation between concepts by clustering the context between two concepts composing association rule. Last, find generalized pattern name by clustering the clustered patterns. To verify the proposed method, we extract relation between concepts and evaluate the result using documents set provide by TREC(Text Retrieval Conference). The result shows that proposed method cant provide useful information that describes relation between concepts.