• 한국콘텐츠학회논문지
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• 제21권3호
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• pp.121-130
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• 2021

다양한 산업 분야의 서비스 개발 경쟁 심화로 인해 긍정적인 사용자 경험을 제공하는 완성도 높은 서비스 제작의 중요성이 강조되고 있다. 이에 서비스 완성도와 효용에 대한 검증 방법으로 사용성 평가가 중요하게 인식되고 있지만, 일반적 사용성 평가 방법은 획일적인 구성으로 인해 다양한 참여자의 특성을 고려하지 못하는 한계가 있다. 이러한 한계가 평가 효율을 저하시킬 수 있기 때문에 이를 개선할 새로운 평가 방법의 가이드라인 개발이 필요한 실정이다. 이에 본 연구에서는 아동이 참여하는 사용성 평가에서 고려해야 하는 특성을 정의하고, 평가 효율을 증대시킬 수 있도록 원격 사용성 평가 구성 및 진행을 위한 가이드라인을 제안하였다. 또한 제안한 가이드라인을 기반으로 설계한 사용성 평가 실험을 진행하였으며, 이 과정에서 가이드라인의 효용을 검증하고 보완이 필요한 사항을 도출하였다. 본 연구를 통해 제안한 아동 대상 원격 사용성 평가 가이드라인이 아동을 대상으로 개발한 서비스의 사용성 평가 설계를 위한 기반 자료로 활용될 수 있을 것으로 기대한다.

• 임상간호연구
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• 제27권2호
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• pp.165-178
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• 2021

Purpose: To analyze nurses' shift work according to the government guidelines for night work and their perceptions of their work schedules. Methods: The study sample included 487 nurses who provided information on their schedules, including the normal working hours of each shift, and overtime per shift during September 2020. Nurses' perceptions were measured in terms of satisfaction, appropriateness for work-life balance, and fairness to their work schedule. Results: One-third of the respondents worked more than 40 hours per week. The average overtime hour was 1.14 hours per shift. Unsocial hours (8 pm to 6 am on weekdays, midnight to midnight on weekends and public holidays) accounted for 56.4% of all working hours. During their last night shift, on average, nurses worked 9.62 hours and had a break of 39 minutes, although 20.5% reported no break. Sixty-eight percent of nurses had at least one between-shift break shorter than 48 hours after a consecutive night shifts. Fifty-seven percent were satisfied with their schedule. One-third perceived their schedule as appropriate for work-life balance, and two-thirds perceived that days off on weekends and nights were fairly distributed within the unit. Working and overtime hours had an inverse relationship with all three aspects of nurses' perceptions. A higher proportion of unsocial hours and having no breaks during the night shift were associated with lower perceptions of fairness. Conclusion: Reducing working hours, ensuring breaks during night shifts, and increasing rewards for unsocial hours are required to improve nurses' perceptions and reduce turnover due to shift work.

• 한국건축시공학회지
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• 제22권5호
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• pp.463-471
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• 2022

건설업은 타 업종에 비하여 정보비대칭 문제가 복잡하게 산재하고 있는 구조를 갖고 있으며, 현행 국내 건설업 등록과 관련된 건설업종 분류 체계는 신설, 통합, 폐지 등의 과정을 거치면서 종합건설업과 전문건설업으로 구분하여 통·폐합을 추진하고 있다. 건설업 업종분류체계는 건설시장에 진입하는데 지침이 되고, 건설수요자가 적정한 서비스를 제공할 수 있는 공급자를 선정하는데 기준이 될 수 있기 때문에 건설업등록제도의 운용 목적이나 취지로 판단할 때, 건설업종 분류 체계를 합리적으로 검토하여 설정되는 것이 매우 중요하다. 본 연구에서는 국내의 건설업 등록 업종 분류체계에 관한 리스크 요인을 고려하여 개선 가능성을 검토하고자 하는데 목적이 있다. 이를 위하여 일본, 미국, 호주 등의 해외의 건설업 면허나 등록제도에서 운영하고 있는 건설업종 분류 체계에 대한 사례 조사를 수행하여 이를 국내 업종 분류 체계와 비교하여 시사점 및 개선 방향에 대하여 검토하였다.

• 동의생리병리학회지
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• 제35권2호
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• pp.47-55
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• 2021

In order to ensure the fact that eight principle pattern differentiation is used clinically as a basic guideline for Korean medicine practice, the definition, role and method of yin-yang pattern differentiation with its case report were explored at first. Yinyang Pattern Differentiation is a method of discriminating human tendencies or morbidity based on the yin and yang characteristics expressed in living bodies. And yin and yang are the two contrasting characteristics and aspects of the interaction when certain physical conditions that have a lasting effect on the human physiological metabolic function are correlated with the morbidity. Specific methods of yinyang pattern differentiation can be divided into several types of yin and yang indicators. First, time and space factors like day and night, hot and cold seasons, above and below, topographical districts. Second, colors and pulse and their/or relative clearness and muddiness, hardness and softness, moving and resting. Third, diagnose yin and yang patterns through distinguishing the true and false of a fever and cold in an emergency phase such as increase of brain pressure and shock state. Fourth, general characteristics of the propensity and constitution of a subject such as body type, speech, behavior, and physiological metabolism. And for clinical use, these were summarized again as a symptom indicators of physical signs and color, pulse, tongue and questionnaire indicators of propensity, body type, and space-time characteristics. Conclusively, it was confirmed that yinyang pattern differentiation has its own diagnostic significance which is distinct from exterior-interior, cold-heat and deficiency-excess pattern differentiation.

• Journal of Gastric Cancer
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• 제23권1호
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• pp.224-249
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• 2023

Gastric cancer is heterogeneous in morphology, biology, genomics, and treatment response. Alterations in human epidermal growth factor receptor 2 (HER2) overexpression, microsatellite instability (MSI) status, programmed death-ligand 1 (PD-L1) levels, and fibroblast growth factor receptor 2 (FGFR2) can be used as biomarkers. Since the combination of fluoropyrimidine/platinum plus trastuzumab that was investigated in the ToGA trial was approved as a standard of care in HER2-positive patients in 2010, no other agents showed efficacy in the first- (HELOISE, LOGiC, JACOB trials) and second- (TyTAN, GATSBY, T-ACT trials) line treatments. Despite the success in treating breast cancer, various anti-HER2 agents, including a monoclonal antibody (pertuzumab), an antibody-drug conjugate (ADC; trastuzumab emtansine [T-DM1]), and a small molecule (lapatinib) failed to translate into clinical benefits until the KEYNOTE-811 (first-line) and DESTINY-Gastri01 (≥second-line) trials were conducted. The incorporation of HER2-directed treatment with immune checkpoint inhibitors in the form of a monoclonal antibody or ADC is now approved as a standard treatment. Despite the promising results of new agents (engineered monoclonal antibodies, bi-specific antibodies, fusion proteins, and small molecules) in the early phase of development, the management of HER2-positive gastric cancer requires further optimization to achieve precision medicine with a chemotherapeutic backbone. Treatment resistance is a complex process that can be overcome using a combination of chemotherapy, targeted agents, and immune checkpoint inhibitors, including novel agents. HER2 status must be reassessed in patients undergoing anti-HER2 treatment with disease progression after the first-line treatment. As a general guideline, patients who need systemic treatment should receive chemotherapy plus targeted agents, anti-angiogenic agents, immune checkpoint inhibitors, or their combinations.

• 대한예방한의학회지
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• 제27권1호
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• pp.69-87
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• 2023

Objectives : This study collected and analyzed information related to preventive formulas from continuously published and revised COVID-19 treatment guidelines in various regions of China. Methods : We collected treatment guidelines published in different regions of China and categorized formulas for prevention and medical observation period listed in them according to the editions. The categorized preventive formulas were compared by type and target group. Results : Herbal medicines used for prevention included formulas derived from Korean medical classics, such as Okbyeongpungsan(玉屏風散) and Eunkyosan(銀翹散). The newly composed formulas, totaling over 100, were created by adding, subtracting, and combining formulas such as Sang-gukeum(桑菊飮), Eunkyosan(銀翹散), Sasammaekmundongtang(沙參麥門冬湯), Okbyeongpungsan(玉屏風散), Gwakhyangjeong-gisan(藿香正氣散), and Soshihotang(小柴胡湯). Patent medicines including Huoxiangzhengqi capsule(藿香正氣膠囊), Lianhuaqingwen capsule(連花淸瘟膠囊), Shufengjiedu capsule(疏風解毒膠囊), and Jinhuaqinggan granule(金花淸感顆粒) were frequently used, mainly targeting close contacts. These medicines were used differently depending on the specific population group, such as the general population, the elderly, children, pregnant women, and patients with underlying diseases, and were also applied differently according to the individual's constitution. Conclusion : We were able to identify various background factors contained in the guidelines for the use of preventive formulas presented by TCM group, and understand the social conditions that enabled the group to provide such guidelines. Through this, thorough preparation should be made so that the Korean Medicine can actively respond to another future pandemic.

• 청정기술
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• 제29권1호
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• pp.53-58
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• 2023

This study shows the summary of the economic performance of excess electricity conversion to hydrogen as well as methane and returned conversion to electricity using a fuel cell. The methane production process has been examined in a previous study. Here, this study focuses on the conversion of methane to electricity. As a part of this study, capital expenditure (CAPEX) is estimated under various sized plants (0.3, 3, 9, and 30 MW). The study shows a method for economic optimization of electricity generation using a fuel cell. The CAPEX and operating expenditure (OPEX) as well as the feed cost are used to calculate the discounted cash flow. Then the levelized cost of returned electricity (LCORE) is estimated from the discounted cash flow. This study found the LCORE value was ¢10.2/kWh electricity when a 9 MW electricity generating fuel cell was used. A methane production plant size of 1,500 Nm³/hr, a methane production cost of $11.47/mcf, a storage cost of $1/mcf, and a fuel cell efficiency of 54% were used as a baseline. A sensitivity analysis was performed by varying the storage cost, fuel cell efficiency, and excess electricity cost by ±20%, and fuel cell efficiency was found as the most dominating parameter in terms of the LCORE sensitivity. Therefore, for the best cost-performance, fuel cell manufacturing and efficiency need to be carefully evaluated. This study provides a general guideline for cost performance comparison with LCORE.

• 한국지반공학회논문집
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• 제24권5호
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• pp.15-25
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• 2008

본 논문에서 매년 항만개발 및 항로유지의 목적으로 발생하는 준설토사의 유효활용을 위하여 주요 항만 준설토사에 대하여 오염현황을 조사 및 분석하였다. 그리고 준설물질별 인간의 건강에 대한 피해확률을 과학적으로 추정하는 위해성 평가를 실시하여 공업 및 주거지역에서 직접 인체에 대하여 안전하고 유효하게 활용할 수 있는 기준을 제시하였다. 제시한 기준은 기존의 준설토사 처리.활용기준 및 토양환경보전법상의 환경기준보다 엄격한 것으로 나타났다. 그리고 유효활용에 대한 사전평가를 실시할 수 있는 관련 기준을 근거로 국내 주요항만의 발생준설토사에 대한 오염도를 평가한 결과, 일부 항만에서 카드뮴(Cd), 비소(As), 크롬(Cr) 및 아연(Zn)이 환경기준을 초과하는 것으로 나타나 정밀한 조사가 이루어져야 할 것으로 나타났지만 대부분 항만에서 발생한 준설토사는 유효활용이 가능한 것으로 나타났다.

• 한국의사학회지
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• 제35권1호
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• pp.37-44
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• 2022

Uirimchalyo (醫林撮要) was published in advance of the Donguibogam (東醫寶鑑) in the middle of the Joseon Dynasty. This book was a pioneering form of the Donguibogam. This paper examines the acupuncture and moxibustion methods used within Uirimchalyo. Because this book was produced for the general public as well as professional Korean medicine doctors, it did not present complex symptom classification and complicated acupuncture prescriptions. Instead, it summarized acupoints in a simple way and could be used as a standardized treatment guideline. In addition, in the acu-moxa methods of the Uirimchalyo, moxibustion was used more than acupuncture. This implies that the author's intention was to treat the disease gently, and furthermore, that the book inherits the acu-moxa method of Hyangyakjipseongbang (鄕藥集成方). There are many suggestions of experienced prescriptions, which can be seen as focusing on experience-based medicine. In addition, the characteristic of not using many acupuncture points served as the cause of the emergence of Saam acupuncture techniques.

• 대한한방부인과학회지
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• 제37권1호
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• pp.40-59
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• 2024

Objectives: Since infertility has been big social issue in Korea, this study aims to analyze the domestic study trends in Korean Medicine (KM) for female infertility treatment. Methods: Case studies applying KM treatment on female infertility were selected through 5 domestic journal databases. General characteristics, interventions, outcomes and results and the quality of the reports were analyzed. Especially, the quality assessments of studies were made using CAse REport (CARE) guideline and Joanna Briggs Institute (JBI) critical appraisal checklist. Results: 14 studies (22 cases) were finally selected for the analyzation. The mean age of the participants was 35.1 and the most common factor of female infertility in this study was Uterine factor. Herbal medicine was applied in all studies, and acupuncture was also used frequently. Most cases reported pregnancy of the participants. According to quality assessment, 'Diagnostic challenges', 'Intervention adherence and tolerability', 'Adverse and unanticipated events', 'Patient perspective' and 'Informed consent' were showed low reporting rates. Conclusions: Korean Medicine treatment for female infertility is expected to be effective. In quality evaluation, there were some items with low reporting rates. Further clinical studies have to be conducted to establish the evidence for the treatment.