• Title/Summary/Keyword: gamma ray dose

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Preparation of Fibrous Adsorbent Modified with Iminodiacetic Acid and Its Co2+, Fe2+, and Pb2+ Adsorption Characteristics (이미노디아세트산을 함유한 섬유상 흡착제 제조 및 코발트, 철, 납 이온 흡착특성)

  • Yang, Hyun-Soo;Choi, Jun-Kyu;Nho, Young Chang
    • Applied Chemistry for Engineering
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    • v.10 no.3
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    • pp.477-485
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    • 1999
  • The grafting of 2,3-epoxypropylmethacrylate (GMA) onto polypropylene fabric was carried out by the $\gamma$-ray preirradiation grafting technique. Subsequently, the GMA-grafted polypropylene fabric was reacted with iminodiacetic acid (IDA) in different mixed solvents to prepare the fibrous metal adsorbent. The grafting extent was found to be dependent on the reaction time, temperature, preirradiation dose and dose rate. The effects of various mixed solvents on the IDA amination onto GMA-grafted polypropylene fabric were investigated. Compared with other mixed solvents, the extent of amination was highest in the dimethylsulfoxide (DMSO)/water, but the reaction did not occur in the water. The adsorption characteristics of various metal ions by the prepared adsorbent were examined when it was immersed in the 100 ppm metal ion solution. The amount of adsorption followed the order:$Pb^{2+}>Co^{2+}>Fe^{2+}$.

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Radiation-induced DNA strand breaks in EL4 cells and mouse spleen lymphocytes (방사선에 의한 EL4 마우스 백혈병세포 및 정상 마우스 비장 임파구 DNA strand breaks의 측정)

  • Kim, Sung-ho;Kim, Tae-hwan;Chung, In-yong;Yoo, Seong-yul;Cho, Chul-koo;Chin, Soo-yil
    • Korean Journal of Veterinary Research
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    • v.31 no.3
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    • pp.329-335
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    • 1991
  • The filter elution technique was used to assay $^{60}Co$ $\gamma$ ray-induced DNA strand breaks(SB) in EL4 mouse leukemia cell and mouse spleen lymphocyte. The lymphocytes were stimulated with lipopolysaccharide (LPS, $20{\mu}g/ml$) to label $[^3H]$ thymidine. EL4 cells and lymphocytes in suspension were exposed at $0^{\circ}C$ to 0Gy, 1Gy, 5Gy, 10Gy or l5Gy for DNA single strand breaks(SSB) assay and 0Gy, 25Gy, 50Gy, 75Gy or 100Gy for DNA double strand breaks(DSB) assay of $^{60}Co$ radiation and elution procedure was performed at pH12.1 and 9.6. The number of DNA strand breaks increased with increasing doses of r rays. The strand scission factor(SSF) was estimated in each experiment (eluted volume 21ml). The slope of SSB EL4 cells was $0.01301{\pm}0.00096Gy^{-1}$ (n=5), the slope of SSB for lymphocytes was $0.01097{\pm}0.00091Gy^{-1}$ (n=5) and the slope of DSB for lymphocytes was $0.001707{\pm}0.0000573Gy^{-1}$ (n=5). Thus EL4 cells were more sensitive to induction of DNA SSB by ionizing radiation than lymphocytes (p<0.005). The ratio of slope of dose-response relationship (SSF versus dose) of lymphocytes DNA SSB as compared with the slope of DNA DSB was 6.4.

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Chemical Changes in Garlic Bulbs Resulting from Ionizing Energy Treatment at Sprout-Inhibition Dose (발아억제 선량의 전리에너지가 마늘의 성분변화에 미치는 영향)

  • Kwon, Joong-Ho;Yoon, Hyung-Sik;Byun, Myung-Woo;Cho, Han-Ok
    • Applied Biological Chemistry
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    • v.31 no.2
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    • pp.147-153
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    • 1988
  • An assessment of the nutritional aspects on irradiated garlic bulbs, stored for 10 months at low$(3{\pm}1^{\circ}C,\;75{\sim}85%\;R.H.)$ and room$(12{\pm}5^{\circ}C,\;75{\sim}85%\;R.H.)$, was performed by means of investigations on the changes in some chemical composition. Ionizing energy treatment at 0.1kGy gamma-ray brought about no significant changes in the moisture content of stored garlic, but it contributed to the reduction of the changes in total available carbohydrate content of stored garlic. After 8 months of storage, the content of free sugars was significantly higher in nonirradiated garlic than in irradiated garlic, especially in low temperature storage. The 0.1kGy irradiation at the sprout-inhibition dose had no apparent effect on the content of ascorbic acid in stored garlic, and sulfurcontaining amino acids appeared to be little affected by the irradiation at 0.1kGy, even though there were some sensitive amino acids like glutamic and aspartic acids.

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Assessment of radionuclides from coal-fired brick kilns on the outskirts of Dhaka city and the consequent hazards on human health and the environment

  • M.M. Mahfuz Siraz;M.D.A. Rakib;M.S. Alam;Jubair Al Mahmud;Md Bazlar Rashid;Mayeen Uddin Khandaker;Md. Shafiqul Islam;S. Yeasmin
    • Nuclear Engineering and Technology
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    • v.55 no.8
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    • pp.2802-2811
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    • 2023
  • In a first-of-its-kind study, terrestrial radionuclide concentrations were measured in 35 topsoil samples from the outskirts of Dhaka using HPGe gamma-ray spectrometry to assess the radiological consequences of such a vast number of brick kilns on the plant workers, general as well as dwelling environment. The range of activity concentrations of 226Ra, 232Th, and 40K is found at 19 ± 3.04 to 38 ± 4.94, 39 ± 5.85 to 57 ± 7.41, and (430 ± 51.60 to 570 ± 68.40) Bq/kg, respectively. 232Th and 40K concentrations were higher than the global averages. Bottom ash deposition in lowlands, fly ash buildup in soils, and the fallout of micro-particles are all probable causes of the elevated radioactivity levels. 137Cs was found in the sample, which indicates the migration of 137Cs from nuclear accidents or nuclear fallout, or the contamination of feed coal. Although the effective dose received by the general public was below the recommended dose limit but, most estimates of hazard parameters surpass their respective population weighted global averages, indicating that brick kiln workers and nearby residents are not safe due to prolonged exposures to terrestrial radiation. In addition, the soil around sampling sites is found to be unsuitable for agricultural purposes.

p53 Nuclear Accumulation as a Possible Biomarker for Biological Radio-dosimetry in Oral Mucosal Epithelial Cells

  • Kim, Youn-Young;Kim, Jong-il;Kim, Jin;Yook, Jong-In;Kim, The-Hwan;Son, Young-Sook
    • BMB Reports
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    • v.34 no.2
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    • pp.123-129
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    • 2001
  • Cellular response to ionizing radiation is affected by cell types, radiation doses, and post-irradiation time. Based on the trypan blue dye exclusion assay in normal oral mucosal cells (OM cells), a 48 h post-irradiation was sufffcient and an adequate time point for the evaluation of radiation sensitivity Its $LD_{50}$ was approximately 1.83 Gy To investigate possible biomarkers useful for the biological radiodosimetry of normal epithelial cells (p53, c-fos, cyclin D1, cdc-2, pRb) EGF receptor phosphorylation and Erk activation were evaluated at different radiation doses and different post-irradiation times. From 0.5 Gy, p53 was accumulated in the nucleus of basal cells of the OM raft culture at 4 h post-irradiation and sustained up to 24 h post-irradiation, which suggests that radiation-induced apoptosis or damage repair was not yet completed. The number of p53 positive cells and biosynthesis of p53 were correlated with radiation doses. Both cyclin D1 and c-fos were only transiently induced within 1 h post-irradiation. Cyclin D1 was induced at all radiation doses. However, cfos induction was highest at 0.1 Gy, approximately 7.3 fold more induction than the control, whose induction was reduced in a reverse correlation with radiation dose. The phosphorylation pattern of cdc-2 and pRb were unaffected by radiation. In contrast to A431 tails overexpressing the EGF receptor approximately 8.5 fold higher than normal epithelial, the OM cells reduced the basal level of the EGF receptor phosphorylation in a radiation dose dependent fashion. In conclusion, among radiation-induced biomolecules, the p53 nuclear accumulation may be considered for the future development of a useful marker far biological radiodosimetry in normal epithelial tissue since it was sustained for a longer period and showed a dose response relationship. Specific c-fos induction at a low dose may also be an important finding in this study It needs to be studied further for the elucidation of its possible connection with the low dose radio-adaptive response.

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Evaluation of Reductive Effect of Exposure Dose by Using Air Gap Apron in Nuclear Medicine Related Work Environment (핵의학과 내 작업 환경에서 공기층 납치마의 피폭선량 감소 효과 평가)

  • Lee, Wang-Hui;Ahn, Sung-Min
    • The Journal of the Korea Contents Association
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    • v.14 no.12
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    • pp.845-853
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    • 2014
  • In this study, we measured the dose reaching the OSLD dosimeter by using the regular lead apron, and air gap apron through 3 experiments, and researched the reductive effect of air gap apron on exposure dose based on the 140 keV gamma ray radiating from $^{99m}technetium$, which is the most commonly used in nuclear medicine. As a result, when the gap between the dosimeter and 0.2mm lead plate is 0 Cm, the average value of 10 dosimeters was 0.515 mSv, and when the gap between the dosimeter and lead plate is 20 Cm, the average value of 10 dosimeters was 0.138 mSv, which shows reductive effect of dose as much as 0.388 mSv. When the gap between the dosimeter and 0.5mm lead plate is 0 Cm, the average value of 10 dosimeters was 0.296 mSv, and when the gap between the dosimeter and lead plate is 20 Cm, the average value of 10 dosimeters was 0.075 mSv, which shows reductive effect of dose as much as 0.221 mSv. As we check the cumulative dosage for 3 days, the lead apron without air layer shows average 0.239 mSv, and the air gap apron shows 0.176 mSv, which is actually reduced by 0.062 mSv. As we check the cumulative dosage for a month, the lead apron without air layer shows 0.59 mSv, and the air gap apron shows 0.54 mSv, which is reduced by 0.05 mSv.

A Study on the Radiation Source Effect to the Radiation Shielding Analysis for a Spent-Fuel Cask Design with Burnup-Credit (연소도이득효과를 적용한 사용후핵연료 수송용기의 방사선원별 차폐영향 분석)

  • Kim, Kyung-O;Kim, Soon-Young;Ko, Jae-Hoon;Lee, Gang-Ug;Kim, Tae-Man;Yoon, Jeong-Hyun
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.9 no.2
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    • pp.73-80
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    • 2011
  • The radiation shielding analysis for a Burnup-credit (BUC) cask designed under the management of Korea Radioactive Waste Management Corporation (KRMC) was performed to examine the contribution of each radiation source affecting dose rate distribution around the cask. Various radiation sources, which contain neutron and gamma-ray sources placed in active fuel region and the activation source, and imaginary nuclear fuel were all considered in the MCNP calculation model to realistically simulate the actual situations. It was found that the maximum external and surface dose rates of the spent fuel cask were satisfied with the domestic standards both in normal and accident conditions. In normal condition, the radiation dose rate distribution around the cask was mainly influenced by activation source ($^{60}Co$ radioisotope); in another case, the neutron emitted in active fuel region contributed about 90% to external dose rate at 1m distance from side surface of the cask. Besides, the contribution level of activation source was dramatically increased to the dose rates in top and bottom regions of the cask. From this study, it was recognized that the detailed investigation on the radiation sources should be performed conservatively and accurately in the process of radiation shielding analysis for a BUC cask.

Effect of Gamma Energy of Positron Emission Radionuclide on X-Ray CT Image (양전자 방출 핵종(18F)의 감마에너지가 X선 CT영상에 미치는 영향)

  • Kim, Gha-Jung;Bae, Seok-Hwan;Kim, Ki-Jin;Oh, Hye-Kyong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.10
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    • pp.4418-4424
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    • 2011
  • This study is aimed to assess the effect of the gamma ray of 511keV energy which is emitted from phantom where the positron emission radionuclide was injected on X-ray CT image. As a scanning method, the CT number and pixel value of the reference image where water was injected(0 mCi), and those acquired by changing the capacity of 18F(Fluorine), positron emission radionuclide, into 1 mCi, 2 mCi, 5 mCi, and 10 mCi were measured. As a result of measuring the CT number(HU) of the phantom image where the positron emission radionuclide($^{18}F$) was injected, there were reference water ($-7.58{\pm}0.66$ HU), 1 mCi($-9.85{\pm}0.50$ HU), 2 mCi($-10.27{\pm}0.21$ HU), 5 mCi($-11.31{\pm}0.66$ HU), and 10 mCi($-13.47{\pm}0.38$ HU). Compared with the image where it was filled with water, there was a reduction of 5.89 Hu in 10 mCi, 3.73 in 5 mCi, 2.69 HU in 2 mCi, and 2 HU in 1 mCi. As for the pixel value of the phantom image, there were reference water ($-2.70{\pm}0.75$), 1 mCi($-4.72{\pm}0.58$), 2 mCi($-6.01{\pm}0.78$), 5 mCi($-6.10{\pm}0.84$), and 10 mCi($-8.20{\pm}0.60$). Compared with the reference image, there was a reduction of 5.50 in 10 mCi, 3.40 in 5 mCi, 3.10 in 2 mCi, and 2.02 in 1 mCi. Through this experiment, it was indicated that, with the increase in the dose of the positron emission radionuclide($^{18}F$), the CT number and the pixel value of the image reduced proportionally, and the width of reduction showed a similar value, too. Accordingly, according to the degree of change in X-ray CT image due to the positron emission radionuclide in the quality control item of PET/CT, the proper standard should be established and it should be periodically managed.

Studies on the Preservation of Pork Sausage by Gamma Radiation - Part 2. Influence of Gamma Radiation on the Preservative Effects of 2-(2-Furyl)-3-(5-Nitro-2-Furyl)-Acrylamide and Potassium Sorbate for Pork Sausage - (감마선(線) 조사(照射)에 의한 Pork Sausage의 저장(貯藏)에 관(關)한 연구(硏究) - 제(第) 2 보(報) 방부제(防腐劑)의 방부효과에 미치는 감마선(線) 조사(照射)의 영향(影響) -)

  • Kim, Yun-Jin;Kong, Un-Young;Kwon, Jung-Cheul
    • Korean Journal of Food Science and Technology
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    • v.5 no.1
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    • pp.49-54
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    • 1973
  • Studies were carried out to investigate the relationship of the remaining percentage of antiseptics and the preservative effect of combined antiseptics and gamma radiation on the keeping quality of pork sausage. Antiseptics quantities, total bacterial counts, and pH were examined during the storage at $5^{\circ}C$ and $30^{\circ}C$. The results obtained were summarized as follows: 1) After irradiation, quantities of antiseptics decreased in proportion to the level of dosage and K-SOA showed more radiosensitivity than AF-2 (p<0.01). 2) The remaining percentage of antiseptics during storage were higher in samples of more irradiated and stored at the lower temperature. AF-2 decreased less than K-SOA. 3) The correlation between the increase of total bacteria counts and percentage of antiseptics survival in sausage was highly significant(p<0.01). High doses of irradiation, storage at lower temperature and use of AF-2, however, seemed to be effective in controlling the increase of total bacterial flora. 4) From the relationships among quantities of antiseptics, number of total bacteria and sensory evaluation, it was shown that the most suitable radiation dose was considered to be 0.5 Mrad, which was superior to 0.75 Mrad in keeping qualities and nonirradiation odor. 5) Effect of gamma ray on the heme pigments of sausage surface was not recognized.

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Evaluation of Radiation Shielding Rate of Lead Aprons in Nuclear Medicine (핵의학과에서 사용하는 납 앞치마의 방사선 차폐율 평가)

  • Han, Sang-Hyun;Han, Beom-Heui;Lee, Sang-Ho;Hong, Dong-Heui;Kim, Gi-Jin
    • Journal of radiological science and technology
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    • v.40 no.1
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    • pp.41-47
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    • 2017
  • Considering that the X-ray apron used in the department of radiology is also used in the department of nuclear medicine, the study aimed to analyze the shielding rate of the apron according to types of radioisotopes, thus ${\gamma}$ ray energy, to investigate the protective effects. The radioisotopes used in the experiment were the top 5 nuclides in usage statistics $^{99m}Tc$, $^{18}F$, $^{131}I$, $^{123}I$, and $^{201}Tl$, and the aprons were lead equivalent 0.35 mmPb aprons currently under use in the department of nuclear medicine. As a result of experiments, average shielding rates of aprons were $^{99m}Tc$ 31.59%, $^{201}Tl$ 68.42%, and $^{123}I$ 76.63%. When using an apron, the shielding rate of $^{131}I$ actually resulted in average dose rate increase of 33.72%, and $^{18}F$ showed an average shielding rate of -0.315%, showing there was almost no shielding effect. As a result, the radioisotopes with higher shielding rate of apron was in the descending order of $^{123}I$, $^{201}Tl$, $^{99m}Tc$, $^{18}F$, $^{131}I$. Currently, aprons used in the nuclear medicine laboratory are general X-ray aprons, and it is thought that it is not appropriate for nuclear medicine environment that utilizes ${\gamma}$ rays. Therefore, development of nuclear medicine exclusive aprons suitable for the characteristics of radioisotopes is required in consideration of effective radiation protection and work efficiency of radiation workers.