• Title/Summary/Keyword: gadolinium

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Gliosarcoma of Cerebello-Pontine Angle: A Case Report and Review of the Literature

  • Yoon, Gi-Yong;Oh, Hyuk-Jin;Oh, Jae-Sang;Yoon, Seok-Mann;Bae, Hack-Gun
    • Brain Tumor Research and Treatment
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    • v.6 no.2
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    • pp.78-81
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    • 2018
  • Gliosarcoma (GS), known as variant of glioblastoma multiforme, is aggressive and very rare primary central nervous system malignant neoplasm. They are usually located in the supratentorial area with possible direct dural invasion or only reactive dural thickening. However, in this case, GS was located in lateral side of left posterior cranial fossa. A 78-year-old man was admitted to our hospital with 3 month history of continuous dizziness and gait disturbance without past medical history. A gadolinium-enhanced MRI demonstrated $5.6{\times}4.8{\times}3.2cm$ sized mass lesion in left posterior cranial fossa, heterogeneously enhanced. The patient underwent left retrosigmoid craniotomy with navigation system. The tumor was combined with 2 components, whitish firm mass and gray colored soft & suckable mass. On pathologic report, the final diagnosis was GS of WHO grade IV. In spite of successful gross total resection of tumor, we were no longer able to treat because of the patient's rejection of adjuvant treatment. The patient survived for nine months without receiving any special treatment from the hospital.

Effect of Ce0.9Gd0.1O1.95 as a promoter upon the oxygen transfer properties of MgMnO3-δ-Ce0.9Gd0.1O1.95 composite oxygen carrier materials for chemical looping combustion

  • Hwang, Jong Ha;Lee, Ki-Tae
    • Journal of Ceramic Processing Research
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    • v.20 no.1
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    • pp.18-23
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    • 2019
  • Chemical looping combustion (CLC) is a promising carbon capture and storage (CCS) technology whose efficiency and cost primarily relies on the oxygen carrier materials used. In this paper, gadolinium-doped ceria (GDC, Ce0.9Gd0.1O1.95) was added as a promoter to improve the oxygen transfer rate of MgMnO3-δ oxygen carrier materials. Increasing GDC content significantly increased the oxygen transfer rate of MgMnO3-δ-GDC composites for the reduction reaction due to an increase in the surface adsorption of CH4 via oxygen vacancies formed on the surface of the GDC. On the other hand, the oxygen transfer rate for the oxidation reaction decreased linearly with increasing GDC content due to the oxygen storage ability of GDC. Adsorbed oxygen molecules preferentially insert themselves into oxygen vacancies of the GDC lattice rather than reacting with (Mg,Mn)O to form MgMnO3-δ during the oxidation reaction.

A Human Case of Lumbosacral Canal Sparganosis in China

  • Fan, Jian-Feng;Huang, Sheng;Li, Jing;Peng, Ren-Jun;Huang, He;Ding, Xi-Ping;Jiang, Li-Ping;Xi, Jian
    • Parasites, Hosts and Diseases
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    • v.59 no.6
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    • pp.635-638
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    • 2021
  • In this study, we intended to describe a human case of lumbosacral canal sparganosis in People's Republic of China (China). A 56-year-old man was admitted to Xiangya Hospital Central South University in Changsha, Hunan province, China after having an experience of perianal pain for a week. An enhancing mass, a tumor clinically suggested, was showed at the S1-S2 level of the lumbosacral spine by the examination of magnetic resonance imaging (MRI) with gadolinium contrast. The patient was received the laminectomy from S1 to S2, and an ivory-white living worm was detected in inferior margin of L5. In ELISA-test with cerebrospinal fluid (CSF) and serum samples, anti-sparganum antibodies were detected. He had a ingesting history of undercooked frog meat in his youth. By the present study, a human case of spinal sparganosis invaded in lumbosacral canal at the S1-S2 level was diagnosed in China. Although the surgical removal of larvae is known to be the best way of treatment for sparganosis, we administered the high-dosage of praziquantel, albendazole and dexamethasone to prevent the occurrence of another remain worms in this study.

GYAGG/6LiF composite scintillation screen for neutron detection

  • Fedorov, A.;Komendo, I.;Amelina, A.;Gordienko, E.;Gurinovich, V.;Guzov, V.;Dosovitskiy, G.;Kozhemyakin, V.;Kozlov, D.;Lopatik, A.;Mechinsky, V.;Retivov, V.;Smyslova, V.;Zharova, A.;Korzhik, M.
    • Nuclear Engineering and Technology
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    • v.54 no.3
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    • pp.1024-1029
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    • 2022
  • Composite scintillation screens on a base of Gd1.2Y1.8Ga2.5Al2.5O12:Ce (GYAGG) scintillator have been evaluated for neutron detection. Besides the powdered scintillator, the composite includes 6LiF particles; both are merged with a binder and deposited onto the light-reflecting aluminum substrate. Results obtained demonstrates that screens are suitable for use with a silicon photomultiplier readout to create a prospective solution for a compact and low-cost thermal neutron sensor. Composite GYAGG/6LiF scintillation screen shows a pretty matched sensitivity and γ-background rejection with a widely used ZnS/6LiF screens however, possesses forty times faster response.

Development and evaluation of a compact gamma camera for radiation monitoring

  • Dong-Hee Han;Seung-Jae Lee;Hak-Jae Lee;Jang-Oh Kim;Kyung-Hwan Jung;Da-Eun Kwon;Cheol-Ha Baek
    • Nuclear Engineering and Technology
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    • v.55 no.8
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    • pp.2873-2878
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    • 2023
  • The purpose of this study is to perform radiation monitoring by acquiring gamma images and real-time optical images for 99mTc vial source using charge couple device (CCD) cameras equipped with the proposed compact gamma camera. The compact gamma camera measures 86×65×78.5 mm3 and weighs 934 g. It is equipped with a metal 3D printed diverging collimator manufactured in a 45 field of view (FOV) to detect the location of the source. The circuit's system uses system-on-chip (SoC) and field-programmable-gate-array (FPGA) to establish a good connection between hardware and software. In detection modules, the photodetector (multi-pixel photon counters) is tiled at 8×8 to expand the activation area and improve sensitivity. The gadolinium aluminium gallium garnet (GAGG) measuring 0.5×0.5×3.5 mm3 was arranged in 38×38 arrays. Intrinsic and extrinsic performance tests such as energy spectrum, uniformity, and system sensitivity for other radioisotopes, and sensitivity evaluation at edges within FOV were conducted. The compact gamma camera can be mounted on unmanned equipment such as drones and robots that require miniaturization and light weight, so a wide range of applications in various fields are possible.

Monte Carlo simulation and study of REE/PET composites with wide γ-ray protection

  • Tongyan Cui;Ruixin Chen;Shumin Bi;Rui Wang;Zhongjian Ma;Qingxiu Jia
    • Nuclear Engineering and Technology
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    • v.55 no.8
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    • pp.2919-2926
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    • 2023
  • In this paper, rare earth element (REE)/polyester composites were designed with lanthanum oxide, gadolinium oxide, and lutetium oxide as ray shielding agents, and polyethylene terephthalate (PET) as the base. Monte Carlo simulation was carried out using FLUKA software. We found that the radiation protection performance of the composite is affected by the type and amount of REE; a higher amount of REE equated to a better radiation protection performance of the composite. When the thickness of the composite and total thickness of the REE is constant, the number of superimposed layers inside the composite does not affect its shielding performance. Compared with a single-type REE/PET composite, a mixed-type REE/PET composite has a wider range of γ-ray absorption and better radiation protection performance. When the mass ratio of PET to REE is 2:8 and different types of REE are mixed with equal mass, several 0.2 cm-thick mixed-type REE/PET composites can shield >70% of 60 and 80 KeV γ-rays.

Contribution of Microbleeds on Microvascular Magnetic Resonance Imaging Signal

  • Chang Hyun Yoo;Junghwan Goh;Geon-Ho Jahng
    • Progress in Medical Physics
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    • v.33 no.4
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    • pp.88-100
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    • 2022
  • Purpose: Cerebral microbleeds are more susceptible than surrounding tissues and have been associated with a variety of neurological and neurodegenerative disorders that are indicative of an underlying vascular pathology. We investigated relaxivity changes and microvascular indices in the presence of microbleeds in an imaging voxel by evaluating those before and after contrast agent injection. Methods: Monte Carlo simulations were run with a variety of conditions, including different magnetic field strengths (B0), different echo times, and different contrast agents. ΔR2* and ΔR2 and microvascular indices were calculated with varying microvascular vessel sizes and microbleed loads. Results: As B0 and the concentration of microbleeds increased, 𝜟R2* and 𝜟R2 increased. 𝜟R2* increased, but 𝜟R2 decreased slightly as the vessel radius increased. When the vessel radius was increased, the vessel size index (VSI) and mean vessel diameter (mVD) increased, and all other microvascular indices except mean vessel density (Q) increased when the concentration of microbleeds was increased. Conclusions: Because patients with neurodegenerative diseases often have microbleeds in their brains and VSI and mVD increase with increasing microbleeds, microbleeds can be altered microvascular signals in a voxel in the brain of a neurodegenerative disease at 3T magnetic resonance imaging.

Utilities and Limitations of Cardiac Magnetic Resonance Imaging in Dilated Cardiomyopathy

  • Min Jae Cha;Yoo Jin Hong;Chan Ho Park;Yoon Jin Cha;Tae Hoon Kim;Cherry Kim;Chul Hwan Park
    • Korean Journal of Radiology
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    • v.24 no.12
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    • pp.1200-1220
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    • 2023
  • Dilated cardiomyopathy (DCM) is one of the most common types of non-ischemic cardiomyopathy. DCM is characterized by left ventricle (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading conditions. DCM is not a single disease entity and has a complex historical background of revisions and updates to its definition because of its diverse etiology and clinical manifestations. In cases of LV dilatation and dysfunction, conditions with phenotypic overlap should be excluded before establishing a DCM diagnosis. The differential diagnoses of DCM include ischemic cardiomyopathy, valvular heart disease, burned-out hypertrophic cardiomyopathy, arrhythmogenic cardiomyopathy, and non-compaction. Cardiac magnetic resonance (CMR) imaging is helpful for evaluating DCM because it provides precise measurements of cardiac size, function, mass, and tissue characterization. Comprehensive analyses using various sequences, including cine imaging, late gadolinium enhancement imaging, and T1 and T2 mapping, may help establish differential diagnoses, etiological work-up, disease stratification, prognostic determination, and follow-up procedures in patients with DCM phenotypes. This article aimed to review the utilities and limitations of CMR in the diagnosis and assessment of DCM.

Development of a DDA+PGA-combined non-destructive active interrogation system in "Active-N"

  • Kazuyoshi Furutaka;Akira Ohzu;Yosuke Toh
    • Nuclear Engineering and Technology
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    • v.55 no.11
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    • pp.4002-4018
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    • 2023
  • An integrated neutron interrogation system has been developed for non-destructive assay of highly-radioactive special nuclear materials, to accumulate knowledge of the method through developing and using it. The system combines a differential die-away (DDA) measurement system for the quantification of nuclear materials and a prompt gamma-ray analysis (PGA) system for the detection of neutron poisons which disturb the DDA measurements; a common D-T neutron generator is used. A special care has been taken for the selection of materials to reduce the background gamma rays produced by the interrogation neutrons. A series of measurements were performed to test the basic performance of the system. The results show that the DDA system can quantify plutonium of as small as 20 mg and it is not affected by intense neutron background up to 1.57 × 107 s-1 and gamma ray of 4.43 × 1010 s-1. The gamma-ray background counting rate at the PGA detector was reduced down to 3.9 × 103 s-1 even with the use of the D-T neutron generator. The test measurements show that the PGA system is capable of detecting 0.783 g of boron and about 86.8 g of gadolinium in 30 min.

MRI Features of Multiple Cranial Neuropathies in Guillain-Barré Syndrome Occurring after COVID-19 Vaccination: A Case Report (COVID-19 백신 접종 후 발생한 길랑-바레증후군에서 보이는 다발성 뇌신경병증의 MRI 소견: 증례 보고)

  • Youngsoo Soh;Eun Ae Yoo;Eun-Sil Kim;Soo Jung Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.4
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    • pp.964-969
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    • 2023
  • Guillain-Barré syndrome (GBS) is an immune-mediated demyelinating polyneuropathy characterized by progressive, ascending, and symmetrical paralysis. It is known to be triggered by an antecedent infection or vaccination. Recently, GBS development following coronavirus disease 2019 (COVID-19) vaccination has been reported. Cranial neuropathies in typical GBS patients usually involve the facial and the lower cranial nerves (from IX to XII). We report a rare case of multiple cranial neuropathies involving trigeminal, abducens, and facial nerves in a patient who developed GBS following COVID-19 vaccination on the basis of obvious MRI features.