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Effects of YkJungJiHwangTang(YJJHT) on Inhibition of Impairment of Learning and Memory, and Acetylcholinesterase in Amnesia Mice (익정지황탕(益精地黃湯)이 치매병태(痴寐病態)모델에 미치는 영향(影響))

  • Choi Byong-Man;Lee Sang-Ryong
    • Journal of Oriental Neuropsychiatry
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    • v.11 no.2
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    • pp.23-42
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    • 2000
  • Alzheimer's disease(AD) is progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PSI and PS2, and amyloid precursor proteins (APP) overexpression. The present research is to examine the inhibition effect of YJJHT on PS-1, PS-2 and APP overexpression by detected to Western blotting. To verify the EFFects of YJJHT on cognitive deficits further, we tested it on the scopolamine-induced amnesia model of the mice using the Morris water maze tests. and there was ameliorative effects of memory impairment s a protection to scopolamine. YJJHT only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine. whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracellular serum level compared with only scopolamine injection. In conclusion, studies of YJJHT that has been know as anti-choline and inhibition ablilities of APP overexpression, this could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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Effects of KakamBoyanghwanohTang(KBT) on inhibition of impairment of learning and memory, and acetylcholinesterase in amnesia mice (가감보양환오탕(加減補陽還五湯)이 생쥐의 학습(學習)과 기억(記憶)의 감퇴(減退) 및 Acetylcholinesterase의 억제(抑制)에 미치는 영향(影響))

  • Moon, Sung-Soo;Lee, Sang-Ryong
    • Journal of Oriental Neuropsychiatry
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    • v.11 no.1
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    • pp.19-36
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    • 2000
  • Alzheimer's disease (AD) is progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APPs) overexpression. The present research is to examine the inhibition effect of KBT on PS1, PS2 and APPs overexpression by detected to Western blotting. To verify the Effects of KBT on cognitive deficits further, we tested it on the scopolamine (1 mg/kg)-induced amnesia model of the mice using the Morris water maze tests, and there was ameliorative effects of memory impairment as a protection to scopolamine. KBT only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracellular serum level compared with only scopolamine injection. In conclusion, studies of KBT that has been know as anti-choline and inhibition ablilities of APPs overexpression, this could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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Effects of Foot Reflexology on Essential Hypertension Patients (본태성 고혈압 환자에게 미치는 발반사마사지 효과)

  • 박형숙;조규영
    • Journal of Korean Academy of Nursing
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    • v.34 no.5
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    • pp.739-750
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    • 2004
  • Purpose: This study was to evaluate the effects of foot reflexology on blood pressure, serum lipids level and life satisfaction in essential hypertension patients. Method: The research design used was a nonequivalent control group pretest-posttest design. Foot Reflexology was used as the experimental treatment from June 23rd, 2003 until August 31st, 2003. Thirty-four subjects were assigned to an experimental group(18) and control group(16). Foot Reflexology was administered twice a week for 6 weeks and self foot Reflexology was administered twice a week for 4 weeks on the experimental group. Result: There was a significant decrease in systolic blood pressure but no significant decrease indiastolic pressure in the experimental group compared to the control group. The total cholesterol level in the experimental group compared to the control group was not significantly decreased after foot reflexology. However, the triglyceride level in theexperimental group compared to the control group was significantly decreased after foot reflexology. On the other hand, high density lipoprotein and low density lipoprotein levels in the experimental group compared to the control group was not significantly decreased after foot reflexology. Life satisfaction in the experimental group compared to the control group was significantly improved after foot reflexology. Conclusion: The results proved that foot reflexology was an effective nursing intervention to decrease systolic pressure, and triglyceride but not for the blood cholesterol and to improve life satisfaction. Therefore, blood cholesterol should be further evaluated in a larger group of subjects and for a longer period. Further research is regarded as necessary to evaluate and to compareeffects of self-foot reflexology and foot reflexology.

Submodule Level Distributed Maximum Power Point Tracking PV Optimizer with an Integrated Architecture

  • Wang, Feng;Zhu, Tianhua;Zhuo, Fang;Yi, Hao;Shi, Shuhuai
    • Journal of Power Electronics
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    • v.17 no.5
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    • pp.1308-1316
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    • 2017
  • The distributed maximum power point tracking (DMPPT) concept is widely adopted in photovoltaic systems to avoid mismatch loss. However, the high cost and complexity of DMPPT hinder its further promotion in practice. Based on the concept of DMPPT, this paper presents an integrated submodule level half-bridge stack structure along with an optimal current point tracking (OCPT) control algorithm. In this full power processing integrated solution, the number of power switches and passive components is greatly reduced. On the other hand, only one current sensor and its related AD unit are needed to perform the ideal maximum power generation for all of the PV submodules in any irradiance case. The proposal can totally eliminate different small-scaled mismatch effects in real-word condition and the true maximum power point of each PV submodule can be achieved. As a result, the ideal maximum power output of the whole PV system can be achieved. Compared with current solutions, the proposal further develops the integration level of submodule DMPPT solutions with a lower cost and a smaller size. Moreover, the individual MPPT tracking for all of the submodules are guaranteed.

Effects of Boyikcheungnoy-tang (BYCNT) on inhibition of impairment of learning and memory, and acetylcholinesterase in amnesia mice (보익청뇌탕(補益淸腦湯)이 치매병태(痴?病態) 모델에 미치는 영향(影響))

  • Lee Sang-Ryong;Koh Tae-Joon
    • Journal of Oriental Neuropsychiatry
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    • v.12 no.1
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    • pp.151-167
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    • 2001
  • Alzheimer's disease(AD) is a progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylchohnesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APPs)'s overexpression. The present research is to examine the inhibition effect of BYCNT on PS-1, PS-2 and APPs's overexpression by detected to Western blotting. To verify the effects of BYCNT on cognitive deficits further, we tested it on the scopolamine(1mg/kg)-induced amnesia model of the mice using the Morris water maze tests, and there was ameliorative effects of memory impairment as a protection from scopolamine. BYCNT only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracellular serum level compared with only scopolamine injection. In conclusion, studies of BYCNT that has been known as anti-choline and inhibition ablilities of APPs overexpression, this could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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Analysis of Bloggers' Influence Style within Blog

  • Tan, Luke Kien-Weng;Na, Jin-Cheon
    • Journal of Information Science Theory and Practice
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    • v.1 no.2
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    • pp.36-57
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    • 2013
  • Blogs are readily available sources of opinions and sentiments which allows bloggers to exert a certain level of influence over the blog readers. Previous studies had attempted to analyze blog features to detect influence within the blogosphere, but had not studied in details influence at the blogger-level. Other studies studied bloggers' personalities with regards to their propensity to blog, but did not relate the personalities of bloggers to influence. Bloggers may differ in their way or manner of exerting influence. For example, bloggers could be active participants or just passive shares, or whether they express ideas in a rational or subjective manner, or they are received positively or negatively by the readers. In this paper, we further analyze the engagement style (frequency, scope, originality, and consistency of the blog postings), persuasion style (appeals to reasons or emotions), and persona (degree of compliance) of individual bloggers. Methods used include similarity analysis to detect the sharing-creating aspect of engagement style, subjectivity analysis to measure persuasion style, and sentiment analysis to identify persona style. While previous studies analyzed influence at blog site level, our model is shown to provide a fine-grained influence analysis that could further differentiate the bloggers' influence style in a blog site.

Energy-Efficiency and Transmission Strategy Selection in Cooperative Wireless Sensor Networks

  • Zhang, Yanbing;Dai, Huaiyu
    • Journal of Communications and Networks
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    • v.9 no.4
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    • pp.473-481
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    • 2007
  • Energy efficiency is one of the most critical concerns for wireless sensor networks. By allowing sensor nodes in close proximity to cooperate in transmission to form a virtual multiple-input multiple-output(MIMO) system, recent progress in wireless MIMO communications can be exploited to boost the system throughput, or equivalently reduce the energy consumption for the same throughput and BER target. However, these cooperative transmission strategies may incur additional energy cost and system overhead. In this paper, assuming that data collectors are equipped with antenna arrays and superior processing capability, energy efficiency of relevant traditional and cooperative transmission strategies: Single-input-multiple-output(SIMO), space-time block coding(STBC), and spatial multiplexing(SM) are studied. Analysis in the wideband regime reveals that, while receive diversity introduces significant improvement in both energy efficiency and spectral efficiency, further improvement due to the transmit diversity of STBC is limited, as opposed to the superiority of the SM scheme especially for non-trivial spectral efficiency. These observations are further confirmed in our analysis of more realistic systems with limited bandwidth, finite constellation sizes, and a target error rate. Based on this analysis, general guidelines are presented for optimal transmission strategy selection in system level and link level, aiming at minimum energy consumption while meeting different requirements. The proposed selection rules, especially those based on system-level metrics, are easy to implement for sensor applications. The framework provided here may also be readily extended to other scenarios or applications.

Empowering Leadership and Individual Creativity: The Mediation Role of Psychological Empowerment in Facing Covid-19 Pandemic

  • SISWANTI, Yuni;MUAFI, Muafi
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.11
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    • pp.809-816
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    • 2020
  • This study tests and analyzes the influence of empowering leadership on employee creativity which is mediated by psychological empowerment. Researchers conduct survey method on state-owned bank employees (ABC Bank) in Pacitan, East Java, Indonesia. Purposive sampling is selected with Likert scale as measurement. The population of this study is 166 respondents, who are permanent employees of the ABC Bank. The data analysis technique used is SPSS 24. The results of this study find that: (1) there is an influence of empowering leadership on psychological empowerment, (2) there is an influence of empowering leadership on individual creativity, (3) there is an influence of psychological empowerment on individual creativity, and (4) the influence of empowering leadership on individual creativity is mediated by psychological empowerment. This study ignores other types of leadership. Further study is needed to examine other types of leadership besides empowering leadership. The level of analysis of this study is individual, so further study could examine empowering leadership conceptualized at the group level because followers will be influenced not only by the dyadic relationship with the leader, but also by the dynamics of the members of the empowered group. This study provides theoretical enrichment from the aspect of empowering leadership, especially at the individual level. Leaders can increase employee creativity by empowering them to do their jobs. Additionally, by creating a work environment that ensures employees feel empowered psychologically.

A Study on the Relative Importance of Quality Scorecard(QSC) for Open Quality (오픈퀄리티 품질성과지표(QSC)의 중요도 분석 연구)

  • Song, Ho Jun;Kim, Min Gyu;Shin, Wan Seon
    • Journal of Korean Society for Quality Management
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    • v.49 no.1
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    • pp.61-79
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    • 2021
  • Purpose: The purpose of this study is to study the relative weights of Quality Scorecard (QSC) which was developed for a new quality concept, called Open Quality, in the era of Industry 4.0. Open Quality aims to ensure quality responsibility by accurately measuring the quality level and sharing the quality data with stakeholders. Methods: To analyze the importance of QSC, a survey study was conducted based on 10 types of industry. The relative weights of QSC measures are investigated by both the industry types and the organizational life cycle. Further, the relative importance of QSC was analyzed according to the organization's lifecycle. By dividing the aspects with respect to the result data, application method for QSC is further provided. Results: The result indicates that there are significant differences among Korean companies in terms of the level of Industry revolution stages. Among ten industry types, manufacturing and finance sectors show the highest importance of QSC. QSC measures are also considered more importance in growth stage of the maturity cycle than generator and decline stages. Conclusion: When QSC is adopted for Open Quality, its relative weights must be considered to cope with the unique characteristics of industrial types. Besides, QSC's contribution may vary according to the level of maturity of the target company.

Cutting-edge Technologies to Achieve a Higher Level of Modular Construction - Literature Review

  • Lee, Seungtaek;Choi, Jin Ouk;Song, Seung
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.536-542
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    • 2022
  • Cost overruns, schedule delays, and a shortage of skilled labor are common problems the construction industry is currently experiencing. Modularization and standardization strategies have the potential to resolve the various problems mentioned above and have been applied for various construction applications for a long time. However, the level of modularization remains low, and modular construction projects have not been getting the full benefits. Thus, this review investigated the cutting-edge technologies currently being utilized to develop the modular construction field. For this paper, qualified research papers were identified using predetermined keywords from previous related research papers. Identified literature was then filtered and analyzed. According to the included reviews, several technologies are being developed for modular construction. For example, automated design and monitoring systems for modularization were developed. In addition, research labs are utilizing robotic arms for modular construction to achieve a high level of completion in the construction industry, as is seen in the manufacturing industry. Despite these efforts, more research and development are necessary because some automation technologies still require manual activities. Thus, there is great potential for further development of modularization techniques, and further research is recommended to achieve high levels of modularization.

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