• Proceedings of the Korean Society for Bioinformatics Conference
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• 2000.11a
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• pp.45-52
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• 2000

Genomic approach produces massive amount of data within a short time period, New high-throughput automatic sequencers can generate over a million nucleotide sequence information overnight. A typical DNA chip experiment produces tens of thousands expression information, not to mention the tens of megabyte image files, These data must be handled automatically by computer and stored in electronic database, Thus there is a need for systematic approach of data collection, processing, and analysis. DNA sequence information is translated into amino acid sequence and is analyzed for key motif related to its biological and/or biochemical function. Functional genomics will play a significant role in identifying novel drug targets and diagnostic markers for serious diseases. As an enabling technology for functional genomics, bioinformatics is in great need worldwide, In Korea, a new functional genomics project has been recently launched and it focuses on identi☞ing genes associated with cancers prevalent in Korea, namely gastric and hepatic cancers, This involves gene discovery by high throughput sequencing of cancer cDNA libraries, gene expression profiling by DNA microarray and proteomics, and SNP profiling in Korea patient population, Our bioinformatics team will support all these activities by collecting, processing and analyzing these data.

• Journal of KIISE:Software and Applications
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• v.33 no.7
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• pp.615-623
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• 2006

A non-functional requirement is a property or quality that the proposed systems have to support the functional requirements. A non-functional requirement is reflected by quality attribute These non-functional requirements playa crucial role during system development, serving as selection criteria for choosing among decisions. It should be continuously considered through the software development process. In spite of the importance of the non-functional requirements, it received little attention because of ambiguousness and invisibility of non-functional requirements. Therefore non-functional model which is a process to analyze the non-functional requirement is proposed for improving the management efficiency of non-functional requirements. Also, this paper presents the trace among the UML diagrams to the conceptual model. According to the non-functional requirement development process, this paper achieved performance-based case study. After then, non-functional requirement should be traced using the UML diagrams.

• Korean Journal of Digital Imaging in Medicine
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• v.16 no.1
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• pp.7-11
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• 2014

The body to achieve an interaction that are connected to each other. Foot of which plays an important role in motor activity. Insole that has been recently used, have a dynamic functional elements. In particular, support of Arch plays a very important role in terms of a motor function of the human body as a whole. It is possible to predict the proper support Arch with insole, the overall structure of the body there can affect the balance. In this study, by applying the insole which supports the Longitudinal arch and Transverse arch, you are trying to assess the interaction of balance and the body's ability. To target the 20 there is no problem in the sense of balance, college student, and changes were observed by measuring the Center of Position area and distance through the Biorescue device worn before and after led by Arch support. As a result, I showed improved results significantly discount rate after wearing in the Center of Position area and distance to assess the balance ability. Therefore, the correction insole function is to support the Longitudinal arch and Transverse arch to an important role in the foot. It may be that it has a functional element for improving the balance of the function of preventing collapse of the arch during walking, to disperse the weight of the entire foot, us reduce fatigue in the end.

• Journal of Chest Surgery
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• v.32 no.11
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• pp.1017-1022
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• 1999

Background: An increasing number of elderly are referred for open heart surgeries(OHS). These patients are assumed to have significantly increased morbidity and mortality because of compromised functional reserves in their vital organs. We reviewed the results of OHS patients who were 70 years old or older. Material and Method: Thirty six consecutive septuagenarians underwent OHS from 1995 to 1997. Operations were coronary artery bypass grafting(CABG) in 26 including 3 left main surgical angioplasty, valve replacement in 7, MVR+CABG in 2, and ASD closure+TAP in 1. Statistical tests were carried out to compare survivor group with nonsurvivor group in respect to risk factors including NYHA functional class, LVEF, emergent operation, IABP support, CPB/ACC time, ventilator time cardiac index, ICU stay and hospital stay for operative mortality. Result: Operative mortality rate and postoperative complication were 16%(6/36) and 50%(18/36). One-year and 3-year actuarial survival rates were 76%. Nine patients(25%) had major complications including third-degree A-V block(2), respiratory failure(1), stroke(3), renal failure requiring dialysis(3) and postoperative hemorrhage(2). The causes of death were pneumonia(1), bleeding(1), acute renal failure(1), low cardiac output(1), third-degree A-V block(1), and ventricular tachycardia(1). The univariate analysis of mortality shows that NYHA class IV, LVEF<40%, lesser values for C.I, and longer time for ventilatory support were associated with the risk factors(p value=0.03, 0.001, 0.007, and 0.014). The emergent operation, CPB/ACC time, IABP support, ICU stay and hospital stay were not significant. Conclusion: We conclude that cardiac operation can be performed in septuagenarians with acceptable outcomes when done in patients with normal to moderately depressed left ventricular function and adequate functional reserves in their vital organs.

• Membrane Journal
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• v.24 no.4
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• pp.317-324
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• 2014

It is very well known that the conventional polyamide (PA) thin film composite (TFC) reverse osmosis (RO) membranes have excellent permselective properties, but their chlorine tolerance is not good enough. In this study, to improve such chlorine tolerance, microporous membranes containing hydrophilic functional groups such as -COOH were used as a support to prepare PA TFC RO membranes, employing the conventional interfacial polymerization method. Meta-phenylene diamine (MPD) and 2,6-diamine toluene (2,6-DAT) were used as diamine monomers and tri-mesoyl chloride (TMC) as an acid monomer. The membranes prepared were characterized using various instrumental analytical methods and permeation test set-up. The flux obtained from the membranes prepared so was more than $1.0m^3/m^2day$ at 800 psi of operating pressure, while the salt rejection was over 99.0%. The chlorine tolerance of them was also found to be better than that of the membrane prepared by using conventional polysulfone support without hydrophilic functional groups.

• Journal of the Korean Society of School Health
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• v.17 no.2
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• pp.127-150
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• 2004

Objectives: The purpose of this study is to provide a basic structure for the establishment of the direction of school health programs, an overview of the historical changes of school health programs and their results, and a conceptual framework on school health programs. Methods: The data analysis has been done using a statistical almanac, relevant laws and regulations, operation handbook of the program, theses, reports, records of public hearings, and other reports as a technical research primarily based on evidence. The methodology of this research classifies the development and growth transition of school health programs during a historical period through the investigation of regulations, organization, manpower, and its program via its development process and to provide a basic tool to design a solid school health policy. Results: A The growth and development of school health programs The development of school health programs was classified into three different periods including the forthcoming period (1945~1967), the completion period (1967~1993), and the actualization period based on the establishment of legislation for School Health Law, other relevant legislation, and the contents of school health programs (1993~present). B. Policy direction of school health programs School health programs have reestablished their goals and range based on basic direction, and developed the W1it model of information structure for school health program management and its basic structure. Finally, the stepwise support system through the building of the school health support center is recommended. (1) The basic direction of school health programs has proposed 7 basic goals to reestablish the policy direction of health improvement based on total health. (2) The W1it model of information system and the school health information system for school health program management has been developed to utilize positive management. (3) School health policy through the study of the health laws and systems has been developed. The necessity of school health support center for the policy support, functional support and operation support has also been proposed. Conclusions: It is necessary to build a school health support center that consists of health professionals in charge of policy support, functional support, and program support of school health programs in order to realize and develop new policy.

• The Korean Journal of Community Living Science
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• v.22 no.4
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• pp.557-572
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• 2011

This study examines the effect of adult-children support network on the psychological well-being of the single and couple elderly households in rural areas. Adult-children support networks include both structural and functional characteristics. For the purpose of this research, 476 participants, who are older than 60 years old, living in rural areas, were selected. The results of this study are summarized as follows: the average degree of psychological well-being of the rural elderly was high. Emotional support from adult children was higher than economic or instrumental support. In the case of the single elderly households, adult children's economic support was the strongest variable affecting the psychological well-being. In the case of the couple elderly households, adult children's emotional support had the greater effect on psychological well-being. On the basis of this analysis, policy implications regarding the single and couple elderly households in rural areas were discussed.

• The Journal of Korean Physical Therapy
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• v.22 no.1
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• pp.39-45
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• 2010

Purpose: The purpose of this study was to examine changes in functional assessment measures (FAMs) and spatiotemporal gait parameters (STGPs) in healthy older adults before and after a 6-week intervention of a proprioceptive neuromuscular facilitation (PNF) training program. Methods: Thirty healthy older adults (mean age: $73.37{\pm}1.21$ age range: 65-79) were randomly assigned either to an experimental group (participating in a 6-week intervention of PNF training) or a control group (only performing daily activities). Participants in the control group did not receive any training program. Performance was assessed by recording changes in the FAMs and STGPs using functional assessment tools and GAITRite. Results: Participants in the PNF group showed significantly improved functional assessment measures and increased stride length, cadence, velocity, and step width (p<0.05). No significant differences in FAMs and STGPs were found in the control group (p>0.05). Conclusion: Participation in a PNF training program improves FAMs and STGPs, thereby increasing the ability of healthy older adults to maintain dynamic balance during functional performance and gait. These findings support the use of PNF training programs as effective fall-prevention programs for the elderly.

• The Journal of Asian Finance, Economics and Business
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• v.6 no.2
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• pp.277-286
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• 2019

The study aims to analyze the influence of egoistic, altruistic and biospheric value on green functional benefit, green monetary cost, green satisfaction and green loyalty. The study analyzes the effect of green functional benefit and green monetary cost on green satisfaction and green loyalty, as well as green satisfaction on green loyalty. The study employs quantitative methods with customers who have green brand purchase experience in Indonesia. Non-probability sampling was conducted using purposive sampling method based on predetermined criteria, which are customers who have already purchase and use green brand products. A total of 402 samples were analyzed using Structural Equation Modelling. The result shows that the data support hypotheses on egoistic and biospheric value, hypotheses on green functional benefit effect to green satisfaction and green loyalty, as well as green monetary cost effect to green loyalty. The other hypotheses are not supported by data. As a conclusion, it is egoistic and biospheric value that has positive effect on green loyalty, while green functional benefit and green monetary cost act as mediation between the value orientation and green loyalty. As managerial implication, green brand marketing strategy should incorporate egoistic and biospheric values in messages in advertising and promotion.

• Korean Management Science Review
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• v.11 no.2
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• pp.161-184
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• 1994

The purpose of this paper is to suggest a DSS(Decision Support System) framework for managing exchange risks involved in international transactions. To this aim, a number of hedging strategies were suggested and analyzed in their pros and cons. Also, developed were a system architechture and various functional modules for implementing the suggested foreign exchange risk management system and application scenario was demonstrated. Finally, future research areas were indicated.