• The Korean Journal of Legal Medicine
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• 제42권4호
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• pp.146-152
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• 2018

We investigated the neural correlates of accurate eyewitness memory retrieval using functional near-infrared spectroscopy. We analyzed oxygenated hemoglobin ($HbO_2$) concentration in the prefrontal cortex during eyewitness memory retrieval task and examined regional $HbO_2$ differences between observed objects (target) and unobserved objects (lure). We found that target objects elicited increased activation in the bilateral ventrolateral prefrontal cortex, which is known for monitoring retrieval processing via bottom-up attentional processing. Our results suggest bottom-up attentional mechanisms could be different during accurate eyewitness memory retrieval. These findings indicate that investigating retrieval mechanisms using functional near-infrared spectroscopy might be useful for establishing an accurate eyewitness recognition model.

• Molecules and Cells
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• 제40권8호
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• pp.523-532
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• 2017

Functional near-infrared spectroscopy (fNIRS) is a noninvasive optical imaging technique that indirectly assesses neuronal activity by measuring changes in oxygenated and deoxygenated hemoglobin in tissues using near-infrared light. fNIRS has been used not only to investigate cortical activity in healthy human subjects and animals but also to reveal abnormalities in brain function in patients suffering from neurological and psychiatric disorders and in animals that exhibit disease conditions. Because of its safety, quietness, resistance to motion artifacts, and portability, fNIRS has become a tool to complement conventional imaging techniques in measuring hemodynamic responses while a subject performs diverse cognitive and behavioral tasks in test settings that are more ecologically relevant and involve social interaction. In this review, we introduce the basic principles of fNIRS and discuss the application of this technique in human and animal studies.

• 식품과학과 산업
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• 제55권1호
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• pp.2-22
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• 2022

Near-infrared spectroscopy (NIRS) is one of the representative non-destructive and eco-friendly analysis methods used for rapid analysis of various ingredients in the food industry. To develop analysis model with NIRS, Chemometrics are applied after pre-treatment of spectrum. Many studies have been reviewed on the analysis of general and functional components for agricultural and livestock products. In the case of livestock products, some studies have been conducted for on-line analysis. This study investigated results on various samples and component applying near-infrared spectroscopy. Furthermore, the results according to sample condition were compared. It was confirmed that NIRS is applied to various fields in the food industry.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제32권3호
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• pp.99-103
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• 2021

The purpose of this review is to examine the clinical use of functional near-infrared spectroscopy (fNIRS) in children and adolescents with psychiatric disorders. Many studies have been conducted using objective evaluation tools for psychiatric evaluation, such as predicting psychiatric symptoms and treatment responses. Compared to other tools, fNIRS has the advantage of being a noninvasive, inexpensive, and portable method and can be used with patients in the awake state. This study mainly focused on its use in patients with attention-deficit/hyperactivity disorder and autism spectrum disorder. We hope that research involving fNIRS will be actively conducted in various diseases in the future.

• 대한의용생체공학회:의공학회지
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• 제29권2호
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• pp.89-98
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• 2008

NIRS (Near-infrared Spectroscopy) and DOI (Diffuse Optical Imaging) are relatively new, non-invasive, and non-ionizing methods that measure or image optical properties (Scattering and Absorption Coefficient) and physiological properties (Water Fraction, concentration of Oxy-, Deoxy-Hemoglobin, Cytochrome Oxidase, etc) of biological tissues. In this paper, three different types of NIRS systems, mathematical modeling, and reconstruction algorithms are described. Also, recent applications such as functional brain imaging, optical mammography, NIRS based BMI (Brain-Machine Interface), and small animal study are reviewed.

• 전기학회논문지
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• 제58권1호
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• pp.210-215
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• 2009

In this study event-related optical signals were extracted from the prefrontal cortexes using functional near infrared spectroscopy while subjects were carrying out 2-back working memory tasks. Four events such as start, yes, no, and error were considered based on the onsets of the stimulus, positive true responses, positive false responses, and negative responses in the 2-back working memory task, respectively. The optical signals recorded were analyzed by peri-event histograms and power spectrum distributions. The results showed specific characteristics of the event-related optical neuronal signals and an opened possibility of an application to control a non-invasive brain-computer interface system or an object of a virtual reality.

• Journal of the Optical Society of Korea
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• 제19권3호
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• pp.284-296
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• 2015

It has been thought that males tend to use their brain hemispheres more laterally than females. However, recent fMRI studies have shown that there may be no difference in brain lateralization between genders. Functional near-infrared spectroscopy (fNIRS) presents a unique opportunity to acquire real time measurements of blood oxygenation changes to observe neural activity specific to the brain's left and right hemispheres. Using an in-house built multichannel fNIRS system, brain lateralization was observed from seven males and four females according to specially designed tasks for left and right hemisphere activation. The Pearson correlation coefficient and a modified Lateralization Index metric for continuous wave fNIRS systems were calculated to quantify brain lateralization. The preliminary results point to no significant difference in lateral hemodynamic changes between the genders. However, the correlation of symmetrical channel pairs decreased as the experiments progressed. To further develop this study, the subject's performance and the removal of global interference must be implemented for an improved study of brain lateralization.

• 한국멀티미디어학회논문지
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• 제21권5호
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• pp.609-616
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• 2018

In this paper, we designed a multimodal bio-signal measurement system to observe changes in the brain nervous system and vascular system during sleep. Changes in the nervous system and the cerebral blood flow system in the brain during sleep induce a unique correlation between the changes in the nervous system and the blood flow system. Therefore, it is necessary to simultaneously observe changes in the brain nervous system and changes in the blood flow system to observe the sleep state. To measure the change of the nervous system, EEG, EOG and EMG signal used for the sleep stage analysis were designed. We designed a system for measuring cerebral blood flow changes using functional near-infrared spectroscopy. Among the various imaging methods to measure blood flow and metabolism, it is easy to measure simultaneously with EEG signal and it can be easily designed for miniaturization of equipment. The sleep stage was analyzed by the measured data, and the change of the cerebral blood flow was confirmed by the change of the sleep stage.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2018년도 춘계 종합학술대회 논문집
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• pp.167-168
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• 2018

비즈니스 환경에서 창의성은 의사결정 문제해결을 위한 중요한 수단이 되고 있다. 본 연구는 실험 패러다임을 구축하고 기능적 근적외 분광법, 즉 fNIRS (functional Near-Infrared Spectroscopy)를 활용하여 창의성이 비즈니스 문제 해결에 미치는 영향을 뇌 인지 변화를 통해 측정하고자 한다. 본 연구에서는 비즈니스 문제해결 창의성이라는 새로운 차원의 창의성을 fNIRS로 측정하고 이를 경영성과 개선으로 연결하고자 하는 연구노력의 탐색적 수준의 결과를 제시하고자 한다.

• 한국멀티미디어학회논문지
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• 제24권2호
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• pp.295-304
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• 2021

Learning assistance system that continuously measures user's concentration will be helpful to grasp the concentration pattern and adjust the learning method accordingly to improve the learning efficiency. Although a lot of various learning aids have been proposed, there have been few studies on the concentration monitoring system in real time. Therefore, in this study, we developed an Android-based mobile application that can measure concentration during study by using functional near-infrared spectroscopy, which is used to measure brain activity. First, the task accuracy was predicted at a maximum level of 93.75% from the prefrontal oxygenation characteristics measured while performing the visual Q&A task on 11 college students, and a concentration calculation formula based on a linear regression model was derived. Then, a survey on the usability of the mobile application was conducted, overall high satisfaction and positive opinions were obtained. From these findings, this application can be used as a customized learning aid application for users, and further, it can help educators improve the quality of classes based on the level of concentration of learners.