• 제목/요약/키워드: functional factor

검색결과 1,892건 처리시간 0.032초

Novel CRF1-receptor Antagonists from Pulsatilla koreana Root

  • Li, Wei;Noh, Hyojin;Lee, Sunghou;Lee, Min Ho;Lee, Eun Young;Kang, Sangjin;Kim, Young Ho
    • Natural Product Sciences
    • /
    • 제20권4호
    • /
    • pp.281-284
    • /
    • 2014
  • In this study, twenty-one oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. Antagonistic activities were measured in these compounds by the aequorin based cellular functional assay system for the corticotropin releasing factor receptor (CRF1). Of them, compounds 7 - 10 showed the highest degree of CRF1 inhibition further at the concentration of $10{\mu}M$. Moreover, by the analysis based on the structure-activity relationship of isolated saponins, a sugar chain at C-3 and a carboxyl group at C-28, as well as a methyl group at C-23 seems to be key functional elements. To our knowledge, this is the first report on CRF1 inhibition of saponins from P. koreana.

Effects of the Motivation for Rehabilitation on the Functional Performance of Stroke Patients

  • Kil, SoRa;Son, SungMin
    • The Journal of Korean Physical Therapy
    • /
    • 제32권1호
    • /
    • pp.39-43
    • /
    • 2020
  • Purpose: This study examined whether the motivation for rehabilitation influences the functional performance of stroke patients. Methods: To elucidate the same, correlation analysis between the 'rehabilitation motivation level' and 'functional performance improvement' was performed. Thirty-three stroke patients, who were hospitalized in rehabilitation and nursing hospitals, were enrolled in this study. Functional performance was assessed using the 10MWT, FRT, and the BBS. Statistical analysis was performed to determine the correlation between the reactivation symptoms and rehabilitation therapy at four weeks, eight weeks, and 12 weeks. Results: The results showed a significant correlation between the reactivation symptoms and rehabilitation therapy, as evidenced by the 10MWT, FRT, and BBS (8-12 weeks 10M gait test, Berg balance scale for 4-8 weeks, and 8-12 weeks). The FRT did not reveal any significant correlation between the rehabilitation program and reactivation. Conclusion: The present study confirmed that a higher motivation for rehabilitation in stroke patients resulting in a higher likelihood of it acting as a factor in improving their functional ability. Based on the above-mentioned results, this study suggests that a rehabilitation program could be considered for the motivation of patients to participate in a rehabilitation program.

Combined Effects of Physical Evidence and Functional Service at Bulgogi Restaurants on Customers' Store Image and Purchase Behaviors: Application of Video Scenario Technique

  • Hwang, Daye;Chang, Hyeja
    • 한국식생활문화학회지
    • /
    • 제35권2호
    • /
    • pp.181-192
    • /
    • 2020
  • This study aimed to identify whether or not four service situations varying according to positive and negative combinations of physical evidence and functional service influence store image and purchase behavioral intentions of customers at bulgogi restaurants. The video-scenario technique was used for the study. Data were analyzed with the SPSS (Window 19.0) package using frequency analysis, one-way ANOVA, 2 by 2 factorial ANOVA, exploratory factor analysis, and multiple regression analysis to confirm the hypotheses. The combined effect of functional service and physical evidence influenced store image and purchase intention. In terms of seperate effect of physical evidence and functional service, the effect of employee service on store image was more powerful than that of physical evidence, even though the effect differed depending on the situation. Purchase intention was only influenced by functional service quality from employees under the four different scenarios. Thus, when opening a Korean restaurant, proper management of tangible evidence suitable to service, and the prices expected from local customers should be determined. Additionally, extremely high or low levels of physical evidence management should be avoided.

Effects of Acupuncture at GB30, GB34, and BL40 on Functional Recovery after Sciatic Crushed Nerve Injury in Rats

  • Lee, Moon-Kyu;Song, Yun-Kyung;Lim, Hyung-Ho
    • 대한한의학회지
    • /
    • 제31권3호
    • /
    • pp.66-78
    • /
    • 2010
  • Background: Peripheral nerve injuries are a commonly-encountered clinical problem and often result in a chronic pain and severe functional deficits. Objectives: The aim of this study was to evaluate the effects of acupuncture on the descending pain and the recovery of the locomotor function that follows sciatic crushed nerve injury in rats. Method: In order to assess the effects of acupuncture on the descending pain and functional recovery, we investigated the walking track analysis, brain-derived neurotrophic factor (BDNF) and its receptor tyrosine receptor kinase B (TrkB) expression in the sciatic nerve, and on the expressions of c-Fos and nitric oxide synthase in the paraventricular nucleus (PVN) of the hypothalamus and in the ventrolateral periaqueductal gray (vlPAG) region resulting from sciatic crushed nerve injury in rats. Results: Acupuncture treatment at Huantiao (GB30), Yanglingquan (GB34), and Weizhong (BL40) facilitated functional recovery. C-Fos and nitric oxide synthase expressions in the brain and BDNF and TrkB expressions in the sciatic nerve were decreased by acupuncture treatment. The most potent effects of acupuncture were observed at the GB30 acupoint. Conclusion: It is possible that acupuncture can be used for pain control and functional recovery from sciatic nerve injury.

계절변동의 함수적 예측 (Functional Forecasting of Seasonality)

  • 이긍희
    • 응용통계연구
    • /
    • 제28권5호
    • /
    • pp.885-893
    • /
    • 2015
  • 통계청과 한국은행 등 통계작성기관에서 이용되고 있는 계절조정은 연간 경제통계 작성시 시계열을 예측한 후 계절조정방법을 적용하여 1년 후 계절변동을 예측하고 원통계 작성시 원통계에서 이를 제거하여 계절조정계열을 작성하고 있다. 이 경우 계절변동을 효과적으로 예측하는 것이 계절조정계열의 품질 향상을 위해 무엇보다 중요하다. 계절변동은 1년 단위로 비슷한 함수적 형태를 지니면서 변하므로 계절변동은 일종의 함수적 시계열이다. 함수적 시계열은 함수적 주성분분석을 바탕으로 한 함수적 시계열모형으로 예측할 수 있다. 본 연구에서는 함수적 시계열 모형을 이용하여 향후 1년간 계절변동을 예측하는 방안을 마련하고 X-11 방식 등 기존의 예측방법과 비교하여 유용성을 파악하였다.

패밀리 레스토랑의 브랜드 심벌이 브랜드 이미지, 선호도 및 구매의도에 미치는 영향 (The Effect of a Family Restaurant's Brand Symbol on Brand Image, Preference, and Purchasing Intention)

  • 김기영;이용호;최동희
    • 한국조리학회지
    • /
    • 제17권3호
    • /
    • pp.33-46
    • /
    • 2011
  • 본 연구는 패밀리 레스토랑의 브랜드 심벌이 브랜드 이미지와 선호도 및 구매의도에 미치는 영향에 관한 것이다. 본 연구 결과, 브랜드 심벌을 시각적 기호로서 기능적 요소, 가치적 요소, 심미적 요소의 3가지 요인이 추출되었고 이중 기능적 요소와 심미적 요소가 브랜드 이미지와 선호도에 영향을 미치는 것으로 나타났으며, 이러한 브랜드 이미지와 선호도는 다시 구매의도에 영향을 미치는 것으로 나타났다. 그리고 소비자들은 브랜드 심벌에 대하여 그림이나 기호의 마크형보다는 기업명이나 브랜드명이 들어간 로고형을 선호하였고 TV광고보다는 옥외광고가 더욱 인지도를 높인다고 응답 하였다. 이러한 결과들을 근거로 향후 브랜드 런칭 시 심벌에 대한 디자인은 앞에서 언급한 로고형 심벌을 우선적으로 고려하고 광고는 어느 한곳에 편중되지 않은 옥외광고와 TV광고가 적절히 혼합하여 사용하여야 할 것이다.

  • PDF

Structure and Properties of TLCP/Polyester Composite Fibers

  • Kim, Jun-Young;Kim, Seong-Hun
    • 한국섬유공학회:학술대회논문집
    • /
    • 한국섬유공학회 2003년도 The Korea-Japan Joint Symposium
    • /
    • pp.102-102
    • /
    • 2003
  • TLCP/polyester composite fibers (TPCFs) based on melt blends of PEN, PET, and TLCP were prepared by melt blending and spinning process to achieve high performance fibers. Reinforcement effect and TLCP fibrillar structure resulted in improvement of mechanical properties for TPCFs. The increase in the apparent crystallite size was attributed to the development of larger crystallites and more ordered crystalline structures in the annealed TPCFs. Molecular orientation was an important factor to determine mechanical property of TPCFs.

  • PDF

대학생의 기능성 의류 소재에 대한 인식과 태도에 관한 탐색적 연구 (University Students' Awareness and Attitudes on Functional Clothing Materials)

  • 유화숙;문지현;최라윤;전은경;한은경
    • 한국생활과학회지
    • /
    • 제18권1호
    • /
    • pp.145-155
    • /
    • 2009
  • The purpose of this study is to examine the university students' awareness and attitudes on functional clothing materials, and to explore the effects of subjects' characteristics on the relationship between their attitudes to and images of the functional clothing materials. A total of 500 questionnaires were distributed to university students and 409 of which were used in data analysis. The data were statistically analyzed by frequency, factor analysis, reliability analysis, correlation analysis, t-test, ANOVA. The results were as follows: students thought that the first and foremost 'function' of functional clothing materials is their light-weight. The functions that consumers practically demanded are water-repellency and high absorbency & quick drying. It showed that students have an image that functional clothing materials have special, good and satisfactory qualities. Goretex and Coolmax were the most selected as brands of functional clothing materials which students knew. Attitudes to functional clothing materials revealed positively in the cognitive, behavioral and affectional attitudes. The attitudes had no significant differences according to sex and their major, but they had significant differences by subjects' amount of allowance, frequency of sports participation and sports ability. In other words, the more amount of allowance they get, the more frequently students do exercise, and the higher sports ability they have, the more positive attitude they have. The study says, in conclusion, that their conception of functional clothing materials has positive relations with their attitudes toward them.