• 한국방재학회:학술대회논문집
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• 2008.02a
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• pp.131-134
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• 2008

Increasing the need of national safety management system in order to an epoch-making improvement to scientific disaster management which appears new types of disasters through the exchange of traditional disaster environment and responds actively to the rapid exchange of social environment based on u-IT. Requiring the development of systematical information sharing networking system and sharing realtime data amongst government, local authorities and related organisations under both safety management in normal times and circumstance management in disaster times, and need for the establishment of national safety strategy, which has been strengthened function such as prevention and preparation. This research provides a basic scheme and strategic tasks in order to constitute preventing scientific national disaster prevention structure at anytime and anywhere from disaster which is based on ubiquitous technology and realise the intelligent national disaster prevention system of u-safe Korea.

• Journal of the Korea Society of Computer and Information
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• v.26 no.11
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• pp.191-199
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• 2021

This study aims to present the need to supplement the driver's license renewal test for elderly drivers. In Korea, the proportion of elderly drivers is increasing as the elderly population increases rapidly. Overall the traffic accident rate is decreasing but the traffic accident and death rate from traffic accidents are increasing in older drivers. In this study the assessments and education conducted when renewing the driver's license for elderly drivers conducted in Korea were conducted to find out the necessary tests compared to the current situation of foreign countries. Although it is appropriate to evaluate the three key functional areas of vision, cognition, motor and somatosensory, we currently evaluate visual acurity in vison area. While MMSE-K and Clock drawing tests are not recognizable for mild cognitive impairment in cognitive areas. The motor and somato sensory function to perform driving are not evaluated at all. Therefore for safe driving of older drivers, the test to be conducted during renewal of the driver's license will need to supplement that the visual field and contrast sensitivity in vision area, cognitive function from mild cognitive impairments, and the endurance, functional range of motion and proprioception in motor function area.

• International Journal of Advanced Culture Technology
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• v.9 no.2
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• pp.18-31
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• 2021

The purpose of the present study was to present evidence for driving interventions for the elderly by conducting programs that can improve visual perception and cognitive function in a driving simulator for elderly drivers and analyse their effects. Three elderly subjects who were 65 years or older, did not have physical and cognitive impairments, and were able to drive themselves participated in the present study. A total of 12 intervention sessions, of which subjects participated in 10 sessions of nine different visual perception and cognitive function programs available in a driving simulator, were conducted and pre- and post-program assessments were conducted (two assessments in total). The assessments included the evaluation of visual perception, frontal lobe function, concentration, safe driving behaviour, and self-efficacy. The results showed positive effects of the driving simulator program on the visual perception, frontal lobe function, concentration, safe driving behaviour, and self-efficacy of all subjects. Changes in the simulator results showed remarkable improvement in the response evaluation, judgment evaluation, and predictive power evaluation, but showed difficulties in interference tasks and depth perception in common. The results showed positive effects of driving simulator training on the driving ability of the elderly, and consistent provision of such training is expected to improve the quality of life of the elderly by securing the safety of driving and actively supporting social participation.

• The Korean Journal of Applied Statistics
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• v.27 no.7
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• pp.1197-1205
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• 2014

Typical clinical dose development studies consist of the comparison of several doses of a drug with a placebo. The primary interest is to find therapeutic window that satisfying both efficacy and safety. In this paper, we propose nonparametric method for identifying effective and safe doses in linear placement using score function. The Monte Carlo simulation is adapted to estimate the power and the family-wise error rate(FWE) of proposed procedure are compared with previous methods.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.406-406
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• 2000

In this study, as a part developing an unmanned container terminal (UCT), Ive designed and implemented an Autonomous Ground Vehicle (AGV) that can deliver containers in the port fast and safely as they are scheduled. It is preferable to research the intelligent UCT/AGV for delivering containers all day long without causing any trouble. For the sake of safe and fast AGV driving, we implemented a multiple-sensor system with vision, ultrasonic, and IR sensors and we adapted the hight-speed wireless LAN that satisfies the IEEE 802.11 Standard for hi-directional communication between the main processor in AGV and a host computer. The Pentium-III processor board mounted on the bottom frame in AGV combines and computes the information from sensors and controls the AGV driving. There are also the 80C196KC micro-controllers to control the actuating and steering motors. In addition, a steering function that is defined newly in this paper is heavily concerned in the mechanical design, and it plays an important role when AGV moves along a curve. Experimental results show the fast and safe delivery operations are possible with this UCT/AGV

• Journal of the Korea Institute of Information Security & Cryptology
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• v.27 no.4
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• pp.721-729
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• 2017

In order to take rapid action against malware, efficiency in malware analysis is essential. For instance, it would be helpful to identify and eliminate open-source function bodies or other safe portions out of the target binary codes. In this paper, we propose an tool to create open source dynamic link library files in Windows environment, extract signature information by opensource and compiler version, and compare open source function information to find suspicious function. In addition, the tool can save the information used in the comparison to the DB and use it later, reducing the analysis time overhead.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.14 no.6
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• pp.47-56
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• 2004

Automatic code generating function for security protocol of SPEAR II and IFAD VDM-SL Toolbox supporting formal specification is presented in this paper. Among the functions of these tools we compare and analyze the aspects of functions, users, operation and code generation. And we suggest direction to the developing of safe security S/W. The automatic code generating function for security protocol gives the direction for developing of the safe secure software in formal specification method.

• Biomolecules & Therapeutics
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• v.31 no.2
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• pp.148-160
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• 2023

Depression is a neuropsychiatric disorder associated with persistent stress and disruption of neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses and reduced size of the hippocampus and prefrontal cortex. These alterations are associated with neural dysfunction, including mood disturbances, cognitive impairment, and behavioral changes. Synaptic plasticity is the fundamental function of neural networks in response to various stimuli and acts by reorganizing neuronal structure, function, and connections from the molecular to the behavioral level. In this review, we describe the alterations in synaptic plasticity as underlying pathological mechanisms for depression in animal models and humans. We further elaborate on the significance of phytochemicals as bioactive agents that can positively modulate stress-induced, aberrant synaptic activity. Bioactive agents, including flavonoids, terpenes, saponins, and lignans, have been reported to upregulate brain-derived neurotrophic factor expression and release, suppress neuronal loss, and activate the relevant signaling pathways, including TrkB, ERK, Akt, and mTOR pathways, resulting in increased spine maturation and synaptic numbers in the neuronal cells and in the brains of stressed animals. In clinical trials, phytochemical usage is regarded as safe and well-tolerated for suppressing stress-related parameters in patients with depression. Thus, intake of phytochemicals with safe and active effects on synaptic plasticity may be a strategy for preventing neuronal damage and alleviating depression in a stressful life.

• Journal of Internet Computing and Services
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• v.23 no.3
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• pp.47-56
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• 2022

The safe driving reward system aims to reduce the loss of life and property by reducing the occurrence of accidents by motivating safe driving and encouraging active participation by providing direct reward to vehicle drivers who have performed safe driving. In the case of the existing digital tachograph, the goal is to limit dangerous driving by recording the driving status of the vehicle whereas the safe driving reward system is a support measure to increase the effect of accident prevention and induces safe driving with financial reward when safe driving is performed. In other words, in an area where accidents due to speeding are high, direct reward is provided to motivate safe driving to prevent traffic accidents when safe driving instructions such as speed compliance, maintaining distance between vehicles, and driving in designated lanes are performed. Since these safe operation data and reward histories must be managed transparently and safely, the reward evidences and histories were constructed using the closed blockchain Hyperledger Fabric. However, while transparency and safety are guaranteed in the blockchain system, low data processing speed is a problem. In this study, the sequential block generation speed was as low as 10 TPS(transaction per second), and as a result of applying the acceleration function a high-performance network of 1,000 TPS or more was implemented.

• Journal of Ginseng Research
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• v.44 no.3
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• pp.373-385
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• 2020

Inflammation is an immune response that protects against pathogens and cellular stress. The hallmark of inflammatory responses is inflammasome activation in response to various stimuli. This subsequently activates downstream effectors, that is, inflammatory caspases such as caspase-1, 4, 5, 11, and 12. Extensive efforts have been made on developing effective and safe anti-inflammatory therapeutics, and ginseng has long been traditionally used as efficacious and safe herbal medicine in treating various inflammatory and inflammation-mediated diseases. Many studies have successfully shown that ginseng plays an anti-inflammatory role by inhibiting inflammasomes and inflammasome-activated inflammatory caspases. This review discusses the regulatory roles of ginseng on inflammatory caspases in inflammatory responses and also suggests new research areas on the anti-inflammatory function of ginseng, which provides a novel insight into the development of ginseng as an effective and safe anti-inflammatory herbal medicine.