• Communications of the Korean Mathematical Society
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• v.31 no.1
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• pp.17-25
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• 2016

The notion of hesitant fuzzy semigroups with two frontiers is introduced, and related properties are investigated. Relations between a hesitant fuzzy semigroups with a frontier and a hesitant fuzzy semigroups with two frontiers are discussed. It is shown that the hesitant intersection of two hesitant fuzzy semigroups with two frontiers is a hesitant fuzzy semigroup with two frontiers. We provide an example to show that the hesitant union of two hesitant fuzzy semigroups with two frontiers may not be a hesitant fuzzy semigroup with two frontiers.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.10
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• pp.3373-3389
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• 2022

Exploration of mobile robot without prior data about environments is a fundamental problem during the SLAM processes. In this work, we propose improved version of previous Rmap algorithm by modifying its Exploration submodule. Despite the previous Rmap's performance which significantly reduces the overhead of the grid map, its exploration module costs a lot because of its rectangle following algorithm. To prevent that, we propose a new Rmap+ algorithm for autonomous path planning of mobile robot to explore an unknown environment. The algorithm bases on paired frontiers. To navigate and extend an exploration area of mobile robot, the Rmap+ utilizes the inner and outer frontiers. In each exploration round, the mobile robot using the sensor range determines the frontiers. Then robot periodically changes the range of sensor and generates inner pairs of frontiers. After calculating the length of each frontiers' and its corresponding pairs, the Rmap+ selects the goal point to navigate the robot. The experimental results represent efficiency and applicability on exploration time and distance, i.e., to complete the whole exploration, the path distance decreased from 15% to 69%, as well as the robot decreased the time consumption from 12% to 86% than previous algorithms.

• Journal of the Korean Data and Information Science Society
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• v.24 no.3
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• pp.495-504
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• 2013

Evolutionary algorithms have been applied to multi-objective optimization problems by approximation methods using computational intelligence. Those methods have been improved gradually in order to generate more exactly many approximate Pareto optimal solutions. The paper introduces a new method using support vector machine to find an approximate Pareto frontier in multi-objective optimization problems. Moreover, this paper applies an evolutionary algorithm to the proposed method in order to generate more exactly approximate Pareto frontiers. Then a decision making with two or three objective functions can be easily performed on the basis of visualized Pareto frontiers by the proposed method. Finally, a few examples will be demonstrated for the effectiveness of the proposed method.

• Journal of Ginseng Research
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• v.48 no.2
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• pp.129-139
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• 2024

Liver diseases are a significant global health burden and are among the most common diseases. Ginssennoside Rg3 (Rg3), which is one of the most abundant ginsenosides, has been found to have significant preventive and therapeutic effects against various types of diseases with minimal side effects. Numerous studies have demonstrated the significant preventive and therapeutic effects of Rg3 on various liver diseases such as viral hepatitis, acute liver injury, nonalcoholic liver diseases (NAFLD), liver fibrosis and hepatocellular carcinoma (HCC). The underlying molecular mechanism behind these effects is attributed to apoptosis, autophagy, antioxidant, anti-inflammatory activities, and the regulation of multiple signaling pathways. This review provides a comprehensive description of the potential molecular mechanisms of Rg3 in the development of liver diseases. The article focuses on the regulation of apoptosis, oxidative stress, autophagy, inflammation, and other related factors. Additionally, the review discusses combination therapy and liver targeting strategy, which can accelerate the translation of Rg3 from bench to bedside. Overall, this article serves as a valuable reference for researchers and clinicians alike.

• The Bulletin of The Korean Astronomical Society
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• v.33 no.1
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• pp.63.2-63.2
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• 2008

• Smart Structures and Systems
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• v.1 no.1
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• pp.103-120
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• 2005

• Industrial Engineering and Management Systems
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• v.11 no.2
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• pp.133-133
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• 2012

• Journal of Gastric Cancer
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• v.21 no.4
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• pp.379-391
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• 2021

Purpose: Promoter DNA methylation of various genes has been associated with metachronous gastric cancer (MGC). The cancer-specific methylation gene, cysteine dioxygenase type 1 (CDO1), has been implicated in the occurrence of residual gastric cancer. We evaluated whether DNA methylation of CDO1 could be a predictive biomarker of MGC using specimens of MGC developing on scars after endoscopic submucosal dissection (ESD). Materials and Methods: CDO1 methylation values (TaqMeth values) were compared between 33 patients with early gastric cancer (EGC) with no confirmed metachronous lesions at >3 years after ESD (non-MGC: nMGC group) and 11 patients with MGC developing on scars after ESD (MGCSE groups: EGC at the first ESD [MGCSE-1 group], EGC at the second ESD for treating MGC developing on scars after ESD [MGCSE-2 group]). Each EGC specimen was measured at five locations (at tumor [T] and the 4-point tumor-adjacent noncancerous mucosa [TAM]). Results: In the nMGC group, the TaqMeth values for T were significantly higher than that for TAM (P=0.0006). In the MGCSE groups, TAM (MGCSE-1) exhibited significantly higher TaqMeth values than TAM (nMGC) (P<0.0001) and TAM (MGCSE-2) (P=0.0041), suggesting that TAM (MGCSE-1) exhibited CDO1 hypermethylation similar to T (P=0.3638). The area under the curve for discriminating the highest TaqMeth value of TAM (MGCSE-1) from that of TAM (nMGC) was 0.81, and using the cut-off value of 43.4, CDO1 hypermethylation effectively enriched the MGCSE groups (P<0.0001). Conclusions: CDO1 hypermethylation has been implicated in the occurrence of MGC, suggesting its potential as a promising MGC predictor.

• Journal for History of Mathematics
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• v.15 no.3
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• pp.49-58
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• 2002

The present paper aims to show basic substitution between metaphysics and mathematical abstraction in the philosophy of mathematics. The general troths of metaphysics and the truths particularly relevant to tile nature of mathematical abstraction serve as speculative guides in ordering the content and discussing the nature of the multiple questions which lie between the disputed frontiers of metaphysics and mathematical abstraction.

• Journal for History of Mathematics
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• v.14 no.2
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• pp.69-76
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• 2001

This paper aims to show an inner, basic harmony between metaphysics and current directions in mathematics and in the philosophy of mathematics. In this attempt, the general truths of metaphysics and the truths particularly relevant to the nature of mathematical abstraction serve as speculative guides in ordering the content and discussing the nature of the multiple questions lie between and disputed frontiers of metaphysics and mathematics.