• Journal of Chest Surgery
• /
• v.55 no.2
• /
• pp.101-107
• /
• 2022

Background: Spread through air spaces (STAS) has recently emerged as a prognostic factor in lung adenocarcinoma, but little is known about the association of STAS and its grade with recurrence in neuroendocrine tumors (NETs). This study investigated the prognostic effect of STAS grade in NETs after curative resection. Methods: Seventy-seven patients were retrospectively reviewed, including 9 with typical carcinoid (TC), 6 with atypical carcinoid (AC), 26 with large cell neuroendocrine carcinoma (LCNEC), and 36 with small cell carcinoma (SCC). STAS was defined as the presence of floating tumor cells within air spaces in the lung parenchyma beyond the edge of the main tumor. STAS was classified as grade 1 or 2 depending on whether it was found within or beyond one ×10 objective lens field away from the main tumor margin, respectively. Results: Fifty-four patients (70%) had STAS, including 22% with TC, 50% with AC, 69% with LCNEC, and 86% with SCC. Patients with STAS had more nodal metastasis, lymphatic and vascular invasion, tumor necrosis, and tumor subtypes other than TC. Among STAS cases, grade 2 STAS was present in 33% of AC, 78% of LCNEC, and 87% of SCC. The 5-year recurrence-free survival (RFS) rate was 81%, 63%, and 35% in patients with no STAS, grade 1, and grade 2 STAS, respectively. Multivariate analysis found that grade 2 STAS was an independent negative prognostic factor for RFS. Conclusion: Although STAS itself was not associated with a poor prognosis, grade 2 STAS was an independent negative prognostic factor for RFS.

• Journal of KSNVE
• /
• v.6 no.2
• /
• pp.225-231
• /
• 1996

A free field method using two microphones is used for measuring surface impedance and absorption coefficient of the absorbent materials. It is shown that this method can be performed in a large non-anechoic room. Precise values of the surface impedance can be obtained by changing the spaces between the two microphones. Comparison between experimental values of the surface impedance of the glass wool and the mineral wool and Miki's empirical model shows agreement.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.65 no.12
• /
• pp.2211-2217
• /
• 2016

The Locator/Identifier Separation Protocol (LISP) is a new routing architecture that implements a new semantic for IP addressing. It enables the separation of IP addresses into two new numbering spaces: Endpoint Identifiers (EIDs) and Routing Locators (RLOCs). This approach will solve the issue of rapid growth of the Internet's DFZ (default-free zone). In this paper, we propose an algorithm called the Propagated-Mode Mapping System to improve the map request process of LISP-DDT.

• 제어로봇시스템학회:학술대회논문집
• /
• 1993.10a
• /
• pp.1024-1030
• /
• 1993

In manufacturing press die with free surface, grinding operation is an important post process for surface finish and dimensional accuracy. With the advancement of NC technology. surface grinding operation is increasingly replaced by the gantry type manipulator. As the mechanics for grinding operation is different from machining operation, conventional CAM system for machining operation is hard to apply. In this. paper, we develop a five-axis CAM system by which an efficient gantry trajectory can be planned and verified. The developed system consists of four conceptual modules; namely CAD, PROCESS. CAM, and ANALYSIS. In the CAD module, the machined surface is represented by CL-data or surface modeler, and process parameters are specified by the PROCESS module. Then, the CAM module generates a series of grinding paths based on the grinding mechanics together with process databases for tool spaces and grinding conditions. The generated paths are verified via ANALYSIS module. Validation via real experiments is left for further study.

• Journal of Plant Biology
• /
• v.29 no.1
• /
• pp.67-75
• /
• 1986

An experimental system for the possibility of association between cultured plant cells and a cyanobacterium (N. muscorum) was investigated. The association was established in nitrogen-free medium, and nitrogen source was provided by N. muscorum through its own nitrogen fixation. N. muscorum was distributed on the outer part and intercellular spaces of the cultured plant cells. Polyamines were treated to the nitrogen-free medium to improve the association. Polyamines increased nitrogenase activity and protein amount in the association between N. muscorum and the cultured plant cells, as compared to the association without polyamines. Especially, spermine showed an increasing effect on the nitrogenase activity and the protein content in the association of tobacco and N. muscorum, while spermidine showed similar effect in case of soybean and N. muscorum.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.21 no.12
• /
• pp.1992-2007
• /
• 1997

A new algorithm for planning a collision-free path is developed based on linear prametric curve. In this paper robot is assumed to a point, and two linear parametric curve is used to construct a path connecting start and goal point, in which single intermediate connection point between start and goal point is considered. The intermediate connection point is set in polar coordinate(${\theta}{\delta}$) , and the interference between path and obstacle is mapped into CPS(connection point space), which is defined a CWS GM(circular work space geometry mapping). GM of all obstacles in workspace creates overlapping images of obstacle in CPS(Connection Point Space). The GM for all obstacles produces overlapping images of obstacle in CPS. The empty area of CPS that is not occupied by obstacle images represents collision-free paths in Euclidian Space. A GM based on connection point in elliptic coordinate(${\theta}{\delta}$) is also developed in that the total length of path is depend only on the variable .delta.. Hence in EWS GM(elliptic work space geometry mapping), increasing .delta. and finding the value of .delta. for collision-free path, the shortest path can be searched without carring out whole GM. The GM of obstacles expersses all possible collision-free path as empty spaces in CPS. If there is no empty space available in CPS, it indicates that path planning is not possible with given number of connection points, i.e. path planning is failed, and it is necessary to increase the number of connection point. A general case collision-free path planning is possible by appling GM to configuration space obstacles. Simulation of GM of obstacles in Euclidian space is carried out to measure performance of algorithm and the resulting obstacle images are reported.

• Journal of The Korea Institute of Healthcare Architecture
• /
• v.15 no.3
• /
• pp.9-20
• /
• 2009

Today, as proved in many foreign developed countries, the concept of 'Aging in Place' is the most desirable goal of welfare policy for an aging society. While multi-family housing is the most representative form of residence in Korea, it has not actively reflected convenient space lay-out for the elderly and barrier-free designs. As a foundation for the planning of elderly-friendly multi-family housing, this study suggested the comparative analysis of the five domestic design guidelines for elderly housing so as to apply the elderly-friendly flexibility for apartment units. In result, the most importantly treated items and factors of the silver house guidelines were analyzed, and based on which ten unit houses of domestic apartment housing were evaluated in order to find out the most barrier-like spaces and factors for the present domestic apartment housing to reflect flexibility as elderly housing. Finally, the way to resolve the problem was suggested as a conclusion.

• Journal of The Korea Institute of Healthcare Architecture
• /
• v.24 no.4
• /
• pp.59-67
• /
• 2018

Purpose: The concept of the Barrier-Free Design has steadily expanded into a basic principle of design, which can provide safe and convenient lives not only limited to the disables, elders, and pregnant women, but also to all members of the society. This is what we now know as the Universal Design. In other words, Barrier-Free Design for all is Architectural Approach of Universal Design. Thus, as a future-oriented alternative to school facilities according to social change, this study suggests basic direction of school building planning and concept of universal design considering school facilities characteristics. Methods: The characteristics of school facilities are understood from the perspective of Universal Design. In addition, a survey is conducted to identify the current state of school facilities. Result: Findings from this study are as follows. First, Universal Design of School Building is an integrated characteristic. Integration is intended to create and manage an integrated environment instead of an individual and one-time approach to installation and maintenance of convenience facilities. Second, It is a flexible characteristic to be sustainable. In other words, they aim to be selectable to respond to change. Third, It is a characteristic of accumulation of outstanding cases. This means that not only individual schools but also entire school spaces will be applied to Universal Design to form a virtuous circle of environment improvement. Implications: The results of this study may serve as a basic concept in the design of school buildings.

• Korean Institute of Interior Design Journal
• /
• v.27 no.2
• /
• pp.106-117
• /
• 2018

The purpose of the study is to present the social welfare center planning factors of space for promoting intergenerational exchanges between the elderly and children. To achieve the purpose, the study conducted a survey of professionals on the importance of planning factors. The results are as follows. First, it is surveyed that less high are Korean social welfare center planning and availability extents of space for intergenerational exchanges, while less no profound are the necessity and concern of such spaces. The result suggests that social welfare centers need a concrete planning of space for intergenerational exchanges. Second, it is identified that in order to promote intergenerational exchanges, there need to plan planning factors of each space, especially with focus on 'outdoor space' and 'specific space.' Third, it is revealed that regarding the importance of factors of 'specific space,' physical supports account for the high rates; architectural factors providing free space contribute to the supports of physical development; and decorative factors giving visual effects could be helpful for behaviors. Fourth, it is unveiled that the supports of physical behaviors are of the most importance in 'connecting space'. This would be planned as a path that gives a free access in spaces, with attention being paid to safety. Lastly, it is shown that in the case of 'outdoor space,' the supports of physical development are of the most importance. Given the fact that 'outdoor space' offers a wider scope of activities, and accommodates various available elements in connection with surrounding environments, it is considered that the space would be of help for intergenerational interactions. The study is expected to be utilized as the preliminary data which proposes the social welfare center planning factors of space for promoting intergenerational exchanges between the elderly and children.

• Journal of the Regional Association of Architectural Institute of Korea
• /
• v.21 no.5
• /
• pp.141-152
• /
• 2019

A gradual increase in the number of people with disabilities and the elderly in our everyday life has changed our perceptions toward them. The concept of barrier free space has been gradually incorporated into the social system and into our everyday life, and has further developed into the universal design concept so that creating an environment where all inhabitants of a city are able to enjoy the space of everyday life. Against this backdrop, this study has conducted research on how to improve the accessibility of major public spaces in Wonju, Chuncheon, and Gangneung, or major metropolitan cities of Gangwon Province. The research has been conducted under the assumption that the conditions of utilizing public spaces in those cities will not meet public expectations compared to private spaced despite being iconic cities of Gangwon Province. The field survey results show that the concept of barrier free space is reflected, to some extent, in planning and development although its role in terms of using such space is not up to expectations. In particular, the buildings and facilities built prior to the enforcement of relevant policies are found to leave much to be desired due to unsatisfactory development plans between architecture and urban public space, which necessitates improvement on relevant policies, sincere efforts of local governments, and practical guidelines that can be useful in the implementation stage. Above all, building owners and public administrations are advised to raise their awareness on the concept of universal design so that it is firmly rooted in our everyday life as one of the universal values. It should lead to the efforts of the members of local cities in providing the environment where people are able to enjoy these utilities from the perspective of promoting public welfare.