• Title/Summary/Keyword: frailty effects

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The Evaluation of Feasibility and Predictive Validity of Comprehensive Korean Frailty Instrument: Using the 2008 and 2011 Living Profiles of Older People Survey in Korea (포괄적 한국 노인 허약사정 도구의 적용가능성과 예측타당도 평가: 2008, 2011년 노인실태조사 자료 이용)

  • Oh, Eunmi;Hong, Gwi-Ryung Son
    • Research in Community and Public Health Nursing
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    • v.28 no.2
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    • pp.206-215
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    • 2017
  • Purpose: This study aimed to verify the predictive validity of Comprehensive Korean Frailty Instrument (CKFI) among older adults. Methods: A secondary analysis of data from a prospective cohort study was conducted. Frailty was determined in older adults (N=9,188) according to the data in 2008 and the effects of frailty on adverse outcomes (such as institutionalization and death) were evaluated according to the data in 2011. The Cardiovascular Health Study (CHS) index was used to compare with the predictive validity of CKFI. Results: The prevalence of frailty was 26.3%. With the CKFI, the frail group had a higher risk of negative health outcomes compared to the robust and pre-frail groups after three years. The two of the highest risks identified using the CKFI and CHS index were institutionalization (5.522 times higher) and mortality (3.210 times higher). For both instruments, the survival analysis revealed that the risk of death increased as the degree of frailty increased. Conclusion: The CKFI consisting of self-report items and multidimensional aspects of frailty can be used as a simple instrument for assessing the frailty of older adults residing in a local community in Korea.

Pre-clinical Models and Exercise Effects for Sarcopenia and Frailty (근감소증과 노쇠의 전임상 모델 및 운동 효과)

  • Jee, Hyunseok;Huh, Jung Bin;Kim, Jong-Hee
    • 한국체육학회지인문사회과학편
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    • v.58 no.4
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    • pp.423-433
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    • 2019
  • The purpose of this review is to summarize current knowledge regarding animal sarcopenia and frailty models and their diagnosis indexes. In addition, we introduce the effects of exercise interventions on sarcopenia and frailty syndrome. Data collection and analysis (fifteen published articles from 2005~2017) were conducted by using keywords' sarcopenia index, frailty index, exercise and mice, and so on' in academic search engines such as Google scholar and Pubmed. Sarcopenia and frailty are the representative syndromes in elderly peoples which those symptoms can be effectively prevented or delayed by extremely adjusted long term exercise interventions (The combined oxidative and resistant exercise program might be ideal.).

The effects of elastic band exercises and nutritional education on frailty, strength, and nutritional intake in elderly women

  • Bong, Yena;Song, Wook
    • Korean Journal of Exercise Nutrition
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    • v.24 no.1
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    • pp.37-45
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    • 2020
  • [Purpose] The purpose of this study was to examine the effects of elastic band exercises and nutritional education, as well as to identify the factors influencing frailty, strength, and nutritional intake of elderly women. [Methods] The subjects in this study were 30 elderly women who were divided into four groups. All groups agreed to participate in four programs: health education only (HE), elastic band exercises only (EX), nutritional education only (NU), and elastic band exercises plus nutritional education (EX+NU). Frailty was evaluated by measuring the frailty factors according to Fried et al. Leg strength was measured using a leg-extension machine. Nutritional intake was assessed by the 24-hour recall method and food records. Nutritional intake was analyzed by CAN Pro 5.0 program. [Results] After three months, the prevalence of frailty significantly decreased in the EX+NU group (P=0.013) compared with that of the HE group (P=0.088). There was significant improvement in leg strength in both the EX (P=0.012) and EX+NU groups (P=0.003) compared with that of the HE group (EX, P=0.005; EX+NU, P=0.002). The nutritional intake significantly decreased in the EX group compared with that of the HE group (P<0.05, P<0.05). [Conclusion] The combination of elastic exercises and nutrition education had positive effects on frailty and leg strength, while having negative effects on total calories, carbohydrate, sodium, and iron intake in elderly women. Elastic exercises only had positive effects on leg strength while having negative effects on nutritional intake in elderly women.

On prediction of random effects in log-normal frailty models

  • Ha, Il-Do;Cho, Geon-Ho
    • Journal of the Korean Data and Information Science Society
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    • v.20 no.1
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    • pp.203-209
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    • 2009
  • Frailty models are useful for the analysis of correlated and/or heterogeneous survival data. However, the inferences of fixed parameters, rather than random effects, have been mainly studied. The prediction (or estimation) of random effects is also practically useful to investigate the heterogeneity of the hospital or patient effects. In this paper we propose how to extend the prediction method for random effects in HGLMs (hierarchical generalized linear models) to log-normal semiparametric frailty models with nonparametric baseline hazard. The proposed method is demonstrated by a simulation study.

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A correction of SE from penalized partial likelihood in frailty models

  • Ha, Il-Do
    • Journal of the Korean Data and Information Science Society
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    • v.20 no.5
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    • pp.895-903
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    • 2009
  • The penalized partial likelihood based on restricted maximum likelihood method has been widely used for the inference of frailty models. However, the standard-error estimate for frailty parameter estimator can be downwardly biased. In this paper we show that such underestimation can be corrected by using hierarchical likelihood. In particular, the hierarchical likelihood gives a statistically efficient procedure for various random-effect models including frailty models. The proposed method is illustrated via a numerical example and simulation study. The simulation results demonstrate that the corrected standard-error estimate largely improves such bias.

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Community Resource Linkage to Revitalize Frailty Prevention Programs for Vulnerable Seniors: Persons Receiving Care from Living Support Workers in the Elderly Customized Care Project (취약계층 노인의 허약예방 프로그램 활성화를 위한 지역사회자원연계 사례: 노인맞춤돌봄서비스 생활지원사의 돌봄대상자)

  • Kim, Sun Jung;Yim, Eun Shil;Jang, Hyun Jin
    • Journal of Korean Academy of Rural Health Nursing
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    • v.19 no.1
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    • pp.66-74
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    • 2024
  • Purpose: This study evaluates the effectiveness of providing frailty prevention services by living support workers through a case of community resource connection centered on living support workers to revitalize frailty prevention programs for vulnerable elderly people. Methods: This is a research study using secondary data from a neighborhood health-sharing project among the integrated health promotion projects of one public health center in Daegu Metropolitan City. To assess frailty effects pre-assessments were conducted in August, and post-assessments were conducted in November. Frailty was measured using a 20-item frailty instrument used in home healthcare projects. Data were analyzed using the chi-square, independent t-test, and paired t-test. Results: Preliminary measurements showed that older elderly had higher frailty scores than younger elderly. However, among the elderly aged 75 or older the total frailty score decreased statistically significantly from 5.97 points to 5.30 points (t=3.03, p=.003). Conclusion: The older elderly showed greater effect of frailty prevention than the younger elderly.

The Effects of Home Visit Healthcare Using a Complex Program on Community-dwelling Frail Elders' Strength, Frailty, and Depression (복합 프로그램을 적용한 방문건강관리가 재가허약노인의 체력, 허약, 및 우울 개선에 미치는 영향)

  • Kim, Hee Gerl
    • Research in Community and Public Health Nursing
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    • v.26 no.4
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    • pp.405-414
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    • 2015
  • Purpose: The purposes of this study were to examine the effects of home visit healthcare using a complex program on community-dwelling frail elders' physical strength, frailty, and depression and to compare the effects among three regions. Methods: This study was conducted as a quasi-experimental study using one-group pretest-posttest design. A total of 86 subjects were sampled from three regions (metropolis, small city, and rural area). The program was applied for 14 weeks. This program consisted of disease management by a visiting nurse, exercise with a visiting nurse, self exercise, telephone monitoring, health education, counseling, providing handbook, and incentive. Physical strength was measured by balance, upper-limb, and lower-limb muscle strength. Frailty was measured by the Korean Frail Scale and depression was measured by the Geriatric Depression Scale. Paired t-test and ANCOVA were used to analyze the effects. Results: Physical strength, frailty, and depression were significantly improved after applying the complex program. There were not differences among the regions. Conclusion: Home visit healthcare using a complex program was effective in improving frail elders' physical strength, frailty, and depression. There were not differences among the regions. Therefore, home visit healthcare using a complex program needs to be expanded to other regions.

The Association between Frequency of Social Contact and Frailty in Older People: Korean Frailty and Aging Cohort Study (KFACS)

  • Chon, Doukyoung;Lee, Yunhwan;Kim, Jinhee;Lee, Kyung-eun
    • Journal of Korean Medical Science
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    • v.33 no.51
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    • pp.332.1-332.8
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    • 2018
  • Background: The trend of aging society is occurring globally, and with it, one of the health problems that is emerging is frailty. Efforts are being made to account for the increasing prevalence of frailty, and various modifiable factors are being considered in regards to frailty. Because social contact has shown beneficial effects in terms of health in previous studies, it is increasingly being considered in relation to frailty. The purpose of this study was to assess the association of different types of social contact with frailty status. Methods: A total of 1,200 Korean elders aged 70-84 years old were included in the study. Using Fried's Cardiovascular Health Study index to categorize the frailty status, the relationship between frailty status and frequency of contact (i.e., with family members, friends, or neighbors) was analyzed using multinomial logistic regression accounting for confounders. Results: Adjusting for all covariates, frequency of contact with friends was the most statistically significant. Less frequent contact was associated with a significantly higher odds of pre-frailty: monthly (odds ratio [OR], 2.02; 95% confidence interval [CI], 1.27-3.20), and rarely (OR, 1.87; 95% CI, 1.17-2.99), with daily contact group as reference. Also, those contacting friends monthly (OR, 5.04; 95% CI, 2.29-11.08) or rarely (OR, 3.23; 95% CI, 1.58-6.61) were more likely to be frail compared to the daily group. Conclusion: Frequency of social contact, especially with friends, is strongly associated with frailty.

ML estimation using Poisson HGLM approach in semi-parametric frailty models

  • Ha, Il Do
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.5
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    • pp.1389-1397
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    • 2016
  • Semi-parametric frailty model with nonparametric baseline hazards has been widely used for the analyses of clustered survival-time data. The frailty models can be fitted via an auxiliary Poisson hierarchical generalized linear model (HGLM). For the inferences of the frailty model marginal likelihood, which gives MLE, is often used. The marginal likelihood is usually obtained by integrating out random effects, but it often requires an intractable integration. In this paper, we propose to obtain the MLE via Laplace approximation using a Poisson HGLM approach for semi-parametric frailty model. The proposed HGLM approach uses hierarchical-likelihood (h-likelihood), which avoids integration itself. The proposed method is illustrated using a numerical study.

Evaluation of the Effects of a Frailty Preventing Multi-factorial Program Concentrated on Local Communities for High-risk Younger and Older Elderly People (전.후기 허약 고위험 노인을 대상으로 한 지역사회 중심의 다요인적 허약 예방 프로그램의 효과 평가)

  • Lee, In Sook;Ko, Young;Lee, Kwang Ok;Yim, Eun Shil
    • Research in Community and Public Health Nursing
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    • v.23 no.2
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    • pp.201-211
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    • 2012
  • Purpose: The purpose of this study is to evaluate the effects of a local community based multi-factorial program for high-risk younger and older elderly people. Methods: The quasi-experimental research design (pretest-post test) was employed. Participants were recruited in Seoul and a total of 98 elders completed an 8-week multi-factorial program for preventing frailty. Descriptive statistics, $x^2$-test and GLM were used in the data analysis with SPSS/WIN 15.0. Results: The high-risk elderly people in the younger and older stages showed differences in IADL, TUG and BMI, and after being provided with the multi-factorial program for preventing frailty, some effects were shown on improving the total score of frailty, a physical function, TUG, BMI, depression, subjective feeling of health, and social interaction. Conclusion: The 8-week multi-factorial program for preventing frailty had positive effects on improving physical, emotional and social functions of the high-risk elderly people. It is necessary to evaluate the effects after individual intervention as well as group intervention and to evaluate the effects of the program by setting a control group in the future.