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Pre-clinical Models and Exercise Effects for Sarcopenia and Frailty

근감소증과 노쇠의 전임상 모델 및 운동 효과

  • Received : 2019.05.31
  • Accepted : 2019.07.31
  • Published : 2019.07.31

Abstract

The purpose of this review is to summarize current knowledge regarding animal sarcopenia and frailty models and their diagnosis indexes. In addition, we introduce the effects of exercise interventions on sarcopenia and frailty syndrome. Data collection and analysis (fifteen published articles from 2005~2017) were conducted by using keywords' sarcopenia index, frailty index, exercise and mice, and so on' in academic search engines such as Google scholar and Pubmed. Sarcopenia and frailty are the representative syndromes in elderly peoples which those symptoms can be effectively prevented or delayed by extremely adjusted long term exercise interventions (The combined oxidative and resistant exercise program might be ideal.).

본 연구의 목적은 근감소증 (sarcopenia)과 노쇠 (frailty)의 전임상 모델에 대한 최근의 연구 자료를 수집하고 정리하여 근감소증과 노쇠의 분석적 지수에 대한 정보를 제공하는데 있다. 또한, 근감소증 및 노쇠 증후군의 예방 및 지연에 있어 운동의 효과를 알아보고자 하였다. 연구 자료 수집은 Google scholar 및 Pubmed 검색엔진을 이용하였으며, 'sarcopenia index, frailty index, exercise, and mice' 등의 키워드로 검색된 2005년부터 2017년까지 게재된 15개의 논문을 분석하였다. 근감소증과 노쇠는 고령자에게 나타나는 대표적인 노인성 증후군이지만 개인특성별 장기적인 운동 (유산소와 저항성운동의 조합 또한 최적의 운동처방이 될 수 있겠다.)을 통해 증상의 예방 및 지연 가능성이 시사되었다.

Keywords

References

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