• 열처리공학회지
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• 제8권4호
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• pp.289-301
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• 1995

The effect of Air/$C_3H_8$ gas addition on the compound layer growth of steels nitrocarburised in $NH_3+Air+C_3H_8$ mixed gas atmospheres was investigated. It is considered that amount of residual $NH_3$ was varied according to alternation of Air/$C_3H_8$ mixing ratio and volume content. The compound layer formed from nitrocarburising was composed of ${\varepsilon}-Fe_{2-3}$(C, N) and ${\gamma}^{\prime}-Fe_4$(C, N). According as Air/$C_3H_8$ mixing ratio increased, the superficial content of ${\gamma}^{\prime}-Fe_4$(C, N) within the compound layer was increased, at the same time the growth rate of compound layer and porous layer was increased. In the case of alloy steel at the fixed gas composition, the growth rate of compound layer and porous layer was worse than carbon steel and compound layer phase composition structure primarily consisted of E phase. As the carbon content of materials was increasing in the given gas atmospheres, the growth rate of compound layer and porous layer was increased and the superficial content of ${\varepsilon}-Fe_{2-3}$(C, N) within the compound layer was increased.

• 한국작물학회지
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• 제40권2호
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• pp.221-227
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• 1995

초지에서 white clover의 존속과 우점 모두가 문제시 되고 있다. 본시험은 white clover의 방목방법에 대한 정보를 제공하기 위하여 예취적기의 장?단(1주, 4주)과 이들의 교호가 white clover의 예취수량 및 형태적 특성에 미치는 영향과 이들간의 관계를 구명하고자 pot 시험으로 실시하였던바 그 결과를 요약하면 다음과 같다. 1. 예취적기 4적에 비하여 1적에서는 예취수량 및 주당엽면적과 엽수, 엽병장, 주당포복경장이 감소되나 g당포복경장과 Specific Leaf Area는 증가되었다. 2. 예취적기 1적와 4적를 교호할 경우 예취수량은 1적 또는 4적로 계속예취한 것의 중간정도이었으나 초기에 4적로 예취한 것에서 높은 수량을 보였다. 3. 예취적기를 교호할 경우 잎과 관련한 형질은 예취적기의 장단에 따라 변하였으나 포복경과 관련된 형질은 교호전 예취적기의 영향이 비교적 장기간 지속되었다. 4. 예취적기를 교호할 경우 예취수량은 주당 엽면적, 엽수 및 포복경장과 정의 상관을. SLA와 g당포복경장과는 부의 상관을 보였다.

• 대한의생명과학회지
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• 제10권1호
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• pp.31-34
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• 2004

White blood cells (WBCs) are present in most human ejaculates, but abnormally high concentration of seminal leukocytes may reflect an underlying pathological condition. The World Health Organization (WHO) has defined leukocytospermia as status of more than $10^6$ WBC/mL of semen. The purpose of this study was firstly, to compare the outcomes between conventional IVF and ICSI in leukocytospermia, and secondly, to investigate whether ICSI may be an alternation treatment for patients with leukocytospermia. Total 346 cycles of conventional IVF and ICSI candidates underwent IVF cycles at Eulji Hospital Infertility Clinic. Semen Parameters including concentration, motility, morphology of spermatozoa and concentration of leukocytes were assessed from the raw ejaculates. There was no difference in sperm concentration, motility and morphology. The rates of fertilization and good embryo development from ICSI were significantly higher than those from conventional IVF in leukocytospermia (60.4% ＆ 32.5%, respectively for ICSI group and 44.4% ＆ 28.5%, respectively for IVF group, P<0.00l). The pregnancy rate after ICSI was also higher than that from conventional IVF (34.0% vs 29.1 %, P<0.05). These results indicate that the presence of seminal leukocyes (> 1$\times10^6$ WBC/mL of semen) is adversely related with fertilization, embryo development and pregnancy rate. Therfore the measurement of seminal leukocytes in routine semen analysis appears to be of prognostic value with regard to male fertilizing potential. In conclusion, it is suggested that ICSI is an alternative choice of treatment for patients with leukocytospermia.

• International Journal of Stem Cells
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• 제16권2호
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• pp.202-214
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• 2023

Background and Objectives: To investigate the role of exosomes from periodontal ligament cells (PDLCs) in bone marrow mesenchymal stem cell (BMSC) migration. Methods and Results: Human PDLCs were applied cyclic tension stretching. Exosomes were extracted from cultured PDLCs by ultracentrifugation, then characterized for their size, morphology and protein markers by NTA, TEM and western blotting. The process that PKH26-labeled exosomes taken up by BMSCs was assessed by confocal microscope. BMSC migration was examined by Transwell assay. Exosomes derived from PDLCs were identified. Cyclic tension stretch application on PDLCs can enhance the migration ability of BMSCs through exosomes. The exosomal miRNA expression profiles of unstretched and stretched PDLCs were tested by miRNA microarray. Four miRNAs (miR-4633-5p, miR-30c-5p, miR-371a-3p and let-7b-3p) were upregulated and six (miR-4689, miR-8485, miR-4655-3p, miR-4672, miR-3180-5p and miR-4476) were downregulated in the exosomes after stretching. Sixteen hub proteins were found in the miRNA-mRNA network. Gene Ontology and KEGG pathway analyses demonstrated that the target genes of differentially expressed exosomal miRNAs closely related to the PI3K pathway and vesicle transmission. Conclusions: The exosomes derived from cyclic tension-stretched PDLCs can promote the migration of BMSCs. Alternation of microRNA profiles provides a basis for further research on the regulatory function of the exosomal miRNAs of PDLCs during orthodontic tooth movement.

• 영어어문교육
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• 제3호
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• pp.231-248
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• 1997

With the trend of globalization more people are absorbing in the English learning programs. Not a few attend even the English-Korean translation training course to be semi-professional translators, but we English teachers have already experienced that it is not so easy to translate any language into another, and that it is far more difficult to translate poetry. Much time has been devoted to investigating the problems of translating poetry than any other mode. Poetry translation theory is concerned with the problem of faithfulness to the original poetry. To be a good translator we must fully understand the sound and sense of the original work. But when in translating English poetry into Korean we feel keenly our limits of understanding the sound and style of English poetry, and of expressing them into Korean. Even our sense-oriented translation is far from satisfactory. We often make quite a few mistranslation. Another immediate problem is that of alternation between word-for-word translation and free translation method, but first of all, we should have a perfect knowledge and understanding in English, and a good command of our mother tongue. We should also have a sound interpretation ability because poetry translation is based on the interpretation of the original, and on the shaping of that interpretation. Some doubts have been raised over the feasibility of poetry translation. They say it is not possible to combine in another language the emotion, the form, the style, the musical devices of English poetry. Yet the art of translation has been practiced everywhere in the world. Through this art we can share our experience and culture with foreigners and theirs with us.

• 한국실내디자인학회논문집
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• 제40호
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• pp.42-51
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• 2003

This study aimed at understanding the spatial characteristics in the Tugendhat house. For this study, it is need to analyze the early plans of the Tugendhat house design process. To analyze this, the study leads to how to effect on the real practice with the process. Therefore, this research investigates the conceptional design process of the house. There are 2 main characteristics of the interior space alternation. One is the closed spatial character on the 2nd floor, the other is the open spatial character on the 1st floor. It clearly shows the severance between interior and exterior on the 2nd floor. Each 2nd floor's space volume uses different materials so that each the space can show the individuality. On the 1st floor, however, it seems the interior is not as much open to the exterior, because the materiality and reflection of the glass, the objet of furniture and wall. In case of 1st floor, it has a complex concept as open and close character, because it is using the proper gardening elements and the relationship between the house and site. The exterior characteristic is separated the house from the ground with the podium and the slope, and this leads to have the discontinuity. The house clearly shows the spatial characteristics of the continuity and discontinuity, it proves that Mies tried to move onto modem architecture as a turning point.

• ALGAE
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• 제23권2호
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• pp.119-133
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• 2008

We cultured a tubular marine green alga, originally identified as Capsosiphon groenlandicus (J. Agardh) K.L. Vinogradova, from Amaknak Island, Alaska. The alga had an alternation of heteromorphic generations in which tubular monoecious fronds produced quadriflagellate zoospores and/or biflagellate isogametes. The gametes fused to produce cysts or Codiolum-like zygotes with long, tortuous stalks. Cysts and codiola produced 8-16 aplanospores, which germinated in situ to yield upright fronds. Fronds arising from both aplanospores and zoospores displayed a distinctive development in which non-septate colorless rhizoids from the base of the initially uniseriate, Ulothrix-like filament were transformed into septate uniseriate Ulothrix-like photosynthetic filaments. These transformed filaments then developed new basal non-septate rhizoids. This pattern of rhizoids becoming filaments, which then produced new rhizoids, was repeated to yield a tuft of up to 50 fronds. Periclinal and longitudinal divisions occurred in each filament, starting basally, until the mature tubular thallus was achieved. Pyrenoid ultrastructure revealed several short inward extensions of chloroplast lamellae, each of which was surrounded by pyrenoglobuli. Analysis of ribosomal SSU and ITS sequences placed this alga in the family Ulotrichaceae, order Ulotrichales, together with but as a distinct species from North Atlantic Capsosiphon groenlandicus. Analysis of a partial ITS sequence from authentic Capsosiphon fulvescens, the current name of the type of the genus Capsosiphon, indicated that neither our material nor C. groenlandicus belongs in that genus, and we propose a new genus, Pseudothrix, to accommodate both species. We propose P. borealis for the North Pacific entity formerly called C. groenlandicus and make the new combination P. groenlandica for the Atlantic species.

• Archives of Pharmacal Research
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• 제28권1호
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• pp.100-105
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• 2005

Mancozeb (MCZ) is known to have detrimental effects on the reproductive system, but the toxicity of MCZ on immune responses has not been systematically investigated. We investigated the effects of MCZ exposure on the activities of murine peritoneal macrophages through evaluation of MCZ-induced alteration of nitric oxide (NO) production and tumor necrosis $factor-{\alpha}(TNF-\alpha)$ synthesis. Macrophages were examined ex vivo from mice orally treated with various doses of MCZ for 5 consecutive days per week for 4 weeks (subacute exposure, 250, 1000, 1500 mg/kg/day) followed by culture for 2 $(TNF-{\alpha})$ or 3 days (NO) in the presence of LPS plus $IFN-{\gamma}$. Macrophages from naive mice were also cultured with various concentrations of MCZ (0.05, 0.25, 0.5, 1 and 2 ${\mu}g//mIL$ in the presence of LPS plus $IFN-{\gamma}$ for 2 $(TNF-{\alpha})$ or 3 days (NO) in vitro. NO production was decreased with the in vitro exposure to all concentrations of MCZ. However, the amount of NO production by peritoneal macrophages from MCZ-subacutely exposed mice was increased in comparision with that of control group. In vitro, MCZ suppressed $(TNF-\alpha)$ secretion with significant reduction at 2 ${\mu}g/mL$ MCZ. Conversely, $(TNF-{\alpha})$ release was enhanced ex vivo. This study provides the substantial evidence on MCZ-induced alternation in macrophage activity. In order to clearly understand the contrasting effect of MCZ on peritoneal macrophage activity, it is necessary to further investigate the influence of major metabolite of MCZ (ETU) exposure on the NO production and $(TNF-{\alpha})$ synthesis.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제33권3호
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• pp.73-81
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• 2022

Since dissociative identity disorder (DID) has symptoms similar to schizophrenia, such as auditory hallucinations and delusional thoughts of being controlled, there are difficulties in its differential diagnosis. A 16-year-old adolescent male patient who was previously diagnosed with schizophrenia from a different hospital was admitted to our inpatient psychiatric unit for the evaluation of auditory hallucinations and suicide attempts. Through psychiatric evaluations, it was determined that the patient suffered from identity alternation, dissociation, and amnesia. As for the diagnostic evaluations, the following measures were implemented: a psychiatric interview regarding the diagnostic criteria, mental status examination, laboratory tests, brain imaging studies, electroencephalography, and full psychological test for adolescents, and the self-reported measure of the Adolescent Dissociative Experiences Scale. The patient was diagnosed with DID, and the following treatments were administered: pharmacotherapy, ego state therapy, psychoeducation regarding emotions, trauma-focused psychotherapy including stabilization, and family therapy. Following treatment, in the internal dimensions, the patient was able to recognize the nine alternate identities in charge of his emotions, which established a basis for the potential integration of identities. In the external dimensions, he showed improvements in the aspects of family conflicts and issue of school refusal. This is the first reported case of DID in an adolescent in Korea; it emphasizes the consideration of DID in the differential diagnosis of other mental illnesses such as schizophrenia, bipolar disorder, and posttraumatic stress disorder and expands the treatment opportunities for DID by sharing the procedures of ego state therapy.

• 자원환경지질
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• 제30권3호
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• pp.263-275
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• 1997

Compound calcrete deposits are recognized from the Dadaepo Formation in Dusong peninsula, Pusan, and their textures, structures, morphology, and stratigraphic distribution are examined. The Dadaepo Formation in study area consists of fluvial plain deposits including floodplain-lake deposits, and the compound calcrete deposits occur above floodplain deposits and below lacustrine deposits. The compound calcrete deposits are composed of nodular to massive (micritic), laminar, nodular, nodular to massive (marly), and marly calcrete deposits. In these calcretes, circumgranular and curved cracks, alveolar structures, fitted peloids, tubular fenestrae with laminar micrite wall (rootlet casts), microstalactic calcite, and tepee structures are observed, which indicates that they are calcic paleosols. Considering their stratigraphic occurrences and pedogenic origin, compound calcrete deposits are interpreted to have formed on distal fluvial plain to palustrine environment by the repetetion of deposition and subsequent calcification due to alternation of lake expansion and contraction. The repetetion of calcrete formation suggests that arid climatic condition was alternated with humid condition in short-term period. Such alternated paleoclimatic condition is similar to those of the Sindong and Hayang groups, and indicates that short-term fluctuations from arid to humid climate were prevailing in overall Gyeongsang Basin. In stratigraphic sense, the compound calcrete deposits can be used as a marker deposit for the correlation of the Dadaepo Formation.