• Title/Summary/Keyword: far-field effect

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Cell Culture Microbioassay for the Water Pollution Monitoring (세포배양 생화학적 기법에 의한 수환경오염 평가)

  • 오승민;정규혁
    • Toxicological Research
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    • v.16 no.4
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    • pp.285-291
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    • 2000
  • So far, investigation of environmental pollution has been achieved in field study. This remains the most exhaustive approach, current dimensions of environmental researches and their inherent complexity require that relatively inexpensive and simple laboratory procedures are developed to make possible the screening of large numbers of sites and samples. At this point. microbioassay has been high-lighted. The purpose of this study is to evaluate the water pollution using microbioassay. Two microbioassay methods were optimized and validated for the sensitive and quantitative determination of total toxic effects in the water. EROD(Ethoxyresorufin-O-deethylase) microbioassay was focused to detect PARs, PCBs and dioxinlike components in the water and E-screen assay to xenoestrogens. The EROD microbioassay was executed in rat hepatoma cell line, H4IIE and E-screen assay in MCF7-BUS cell line. Kumho river was selected for this study. 5ι of river water was extracted using combined solid-phase extraction in static adsorption mode with soxhlet extraction. Pollutants adsorbed to the XAD-4 resin were recovered by elution with ethyl acetate and methylene chloride (1 : 9). Toxic effects of extracts were determined by EROD-microbioassay and E-screen assay. EROD activities of water samples were 7.24-72.24 ng/ι MEQ. The estrogenic effect of various water samples is quantitatively evaluated by EEQ. The EEQ of samples range from 0.05 to 6.07 ng-EEQ/ι. These results suggested that Kumho river was highly polluted with organic toxic chemicals.

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Stress intensity factors for periodic edge cracks in a semi-infinite medium with distributed eigenstrain

  • Afsar, A.M.;Ahmed, S.R.
    • Structural Engineering and Mechanics
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    • v.21 no.1
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    • pp.67-82
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    • 2005
  • This study analyzes stress intensity factors for a number of periodic edge cracks in a semiinfinite medium subjected to a far field uniform applied load along with a distribution of eigenstrain. The eigenstrain is considered to be distributed arbitrarily over a region of finite depth extending from the free surface. The cracks are represented by a continuous distribution of edge dislocations. Using the complex potential functions of the edge dislocations, a simple as well as effective method is developed to calculate the stress intensity factor for the edge cracks. The method is employed to obtain the numerical results of the stress intensity factor for different distributions of eigenstrain. Moreover, the effect of crack spacing and the intensity of the normalized eigenstress on the stress intensity factor are investigated in details. The results of the present study reveal that the stress intensity factor of the periodic edge cracks is significantly influenced by the magnitude as well as distribution of the eigenstrain within the finite depth. The eigenstrains that induce compressive stresses at and near the free surface of the semi-infinite medium reduce the stress intensity factor that, in turn, contributes to the toughening of the material.

An Experimental and Analytical study on the Steel Plate Girder Railway bridge in the applying External Post-tensioning Method (강철도교에 대한 외부 후긴장 보강공법의 적용에 관한 실험 및 해석적 연구)

  • Park, Young-Hoon;Cho, Sun-Kyu;Choi, Jung-Youl;Park, Yong-Gul
    • Journal of the Korean Society for Railway
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    • v.9 no.2 s.33
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    • pp.151-159
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    • 2006
  • It analyzed the mechanical behaviors of non-ballasted railway bridge (steel plate girder type) with ballast reinforced on the finite element analysis, field test and laboratory test far the static and dynamic responses. The major objective of this study is to investigate the effects and application of reinforcement for steel plate girder railway bridge by the external post-tensioning method. The reinforcement of non-ballast railway bridge had obviously stable dynamic behaviors due to the additional dead force which was ballast. But in case of static behaviors, static displacements and stresses had increased nearly the allowable values. Therefore we analyzed the mechanical behaviors of non-ballasted railway bridge with ballast reinforced and external post-tensioning reinforced on the finite element analysis and laboratory test for the static and dynamic behavior. As a result, the reinforcement of ballasted railway bridge the external post-tensioning method are obviously effective for the additional dead force which is ballast. The analytical and experimental study are carried out to investigate the post-tension force decrease bending behavior and deflection in composite bridge for serviceability. The servicing railway bridge with ballast reinforced has need of the reasonable reinforcement measures which could be reducing the effect of additional dead load that degradation phenomenon of structure by an unusual. stresses and a drop durability.

A Study on Dynamic Behaviors of Steel Plate Girder bridge with Applying External Post-Tensioning Method (외부 후긴장 공법 적용에 따른 무도상 판형교의 동적거동 분석)

  • Choi, Dong-Ho;Choi, Jung-Youl;Choi, Jun-Hyeok;Park, Yong-Gul
    • Journal of the Korean Society for Railway
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    • v.9 no.2 s.33
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    • pp.160-168
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    • 2006
  • The major objective of this study is to investigate the effects and application of external post-tensioning method far steel plate girder bridge. It analyzed the mechanical behaviors of steel plate girder bridge with applying external post-tensioning on the finite element analysis, field test and laboratory test fur the lateral dynamic characteristics. As a result, the reinforcement of steel plate girder bridge the external post-tensioning method are obviously effective for the lateral dynamic response which is non-reinforced. The analytical and experimental study are carried out to investigate the post-tension force decrease lateral acceleration and deflection on steel plate girder bridge for serviceability. And the external post-tensioning method reduce dynamic maximum displacement(about $10{\sim}24%$), the increase of dynamic safety is predicted by adopting external post-tensioning method. From the dynamic test results of the servicing steel plate girder bridge, it is investigated that the change degree of natural frequency is very low with applying the external post-tensioning method The servicing steel plate girder bridge with external post-tensioning has need of the reasonable reinforcement measures which could be reducing the effect of lateral dynamic behavior that degradation phenomenon of structure by an unusual response characteristic and a drop durability.

Depression in Patients with End-Stage Renal Disease (말기 신장질환자의 우울증)

  • Kim, Seon-Young;Kim, Jae-Min;Yoon, Jin-Sang
    • Korean Journal of Biological Psychiatry
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    • v.15 no.4
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    • pp.265-274
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    • 2008
  • Depression is common in patients with end-stage renal disease(ESRD) and has a negative effect on the quality of life, functional ability, and mortality of the patients, with a prevalence rate as high as 20-25%. Especially, the increasing tendency of mortality in ESRD patients is associated with recent or current depression, and the suicide rate is also increased by depression in patients with ESRD. Therefore, accurate detection and appropriate treatment of depression is very important in ESRD patients. Also, a deferential diagnosis is needed concerning uremic symptoms and depression in ESRD patients. However, there has been little data so far particularly in terms of randomized clinical trials. This review focused on the recent knowledge of depression in ESRD, and could encourage clinical study and trials in this field.

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Investigation on the Turbulence Structure of Reattaching Separated Shear Layer Past a Two-Dimensional Vetrical Fenc(I) (2次元 垂直壁을 지니는 再附着 剝離 斷層 의 亂流構造 에 관한 硏究 (I))

  • 김경천;정명균
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.9 no.4
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    • pp.403-413
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    • 1985
  • Hot-wire measurements of second and third-order mean products of velocity fluctuations have been made in the separated, reattached, and redeveloping boundary layer behind a vertical fence. Mean velocity, wall static pressure distributions have also been measured in the whole flow field. Upstream of the reattachment point, the separated shear layer developes as a free mixing layer, but the gradient of the maximum slope thickness, turbulent intensities and the Reynolds shear stress are higher than that of the mixing layer due to initial streamline curvature and the effects of highly turbulent recirculating flow region. In the reattachment region, Reynolds shear stress and triple products near the surface is far more rapid than the decrease of the shear stress; that is the presence of the solid wall has a marked effect on the apparent gradient diffusivity of intensity or shear stress and throws doubts upon the usefulness of the simple gradient diffusivity model in this region.

Studies on the Tick Killing and Repellent Effects of Two Korean Indigenous Crude Drugs, Radix Jingyu and Fructus Ponciri (두가지 국산생약(國産生藥), 진규와 지실(枳實)의 소진드기 구제(驅除)(살충(殺蟲) 및 기피(忌避)) 효력(效力)에 관한 연구(硏究))

  • Lee, Jang-Nag
    • Korean Journal of Veterinary Research
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    • v.2 no.1
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    • pp.15-26
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    • 1962
  • Decoctions of two Korean indigenous crude drugs. Radix Jingyu(the dried root of Aconitum pseudo-laeve Nakai var. erectum Nakai form. Genuinum Nakai) and Fructus ponciri (the transversely sliced and dried unripe fruit of Poncirus trifoliata Rafinesque), are being utilized by the inhabitants in certain parts of southeastern district of Korea with an empirical belief that these serve as effective insecticides for cattle ticks. Of the two species of cattle ticks so far identified in Korea, Boophilus microplus and Haemaphysalis bispinosum, the former was employed in this experiment as the species occupies nearly 99 percent of the tick population. The results of the experiments herein reported seen to indicate that although the killing power of aqueous extracts of the drugs is minimal, the repellent effect against the ticks, especially of Radix Jingyu, is excellent. It may be of interest to note that the aqueous extract of Radix Jingyu has not proved to be inferior to any of the most effective cattle repellents commercially available. Further studies on these Korean indigenous crude drugs as cattle tick repellents are indicated to find whether active ingredients can be extracted in a hope to materialize an extensive application of these drugs in the field.

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Acoustic Scattering from Circular Cylinder by Periodic Sources (주기적인 음원에 의한 원형 실린더의 음향 산란)

  • Lee, Duck-Joo;Kim, Yong-Seok
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.17 no.1 s.118
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    • pp.41-47
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    • 2007
  • Scattering fields of two dimensional acoustic waves by a circular cylinder are investigated. The present numerical approach for the acoustic scattering problem has difficulties of numerical robustness, long-time stability and suitability of far-field boundary treatments. The time-dependent periodic acoustic source is used to analyze Interference patterns between incident waves and waves reflected by the cylinder. Characteristic boundary algorithms coupled with 4th order Modified-Flux-Approach ENO(essentially non-oscillatory) schemes are employed in generalized coordinates to examine the effect of the wane frequency on the interference patterns. Non-reflecting boundary conditions, which is crustal for accurate computations of aeroacoustic problems, are used not to contaminate scattering fields by reflected waves at the outer boundary. Computed scattering fields show the circumferential acoustic modes generated by interacting between acoustic sources and scattered waves. At a lower frequency, the wave passes almost straight through the cylinder without Interacting with circular cylinder. Simulation results are presented and compared with the analytic solution. Computed RMS-pressure distribution on the cylinder wall is good agreement with exact solution.

Current Status of Intensive Observing Period and Development Direction (집중관측사업의 현황과 발전 방향)

  • Kim, Hyun Hee;Park, Seon Ki
    • Atmosphere
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    • v.18 no.2
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    • pp.147-158
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    • 2008
  • Domestic IOP (intensive observing period) has mostly been represented by the KEOP (Korea Enhanced Observing Period), which started the 5-yr second phase in 2006 after the first phase (2001-2005). During the first phase, the KEOP had focused on special observations (e.g., frontal systems, typhoons, etc.) around the Haenam supersite, while extended observations have been attempted from the second phase, e.g., mountain and downstream meteorology in 2006 and heavy rainfall in the mid-central region and marine meteorology in 2007. So far the KEOP has collected some useful data for severe weather systems in Korea, which are very important in understanding the development mechanisms of disastrous weather systems moving into or developing in Korea. In the future, intensive observations should be made for all characteristic weather systems in Korea including the easterly in the central-eastern coastal areas, the orographically-developed systems around mountains, the heavy snowfall in the western coastal areas, the upstream/downstream effect around major mountain ranges, and the heavy rainfall in the mid-central region. Enhancing observations over the seas around the Korean Peninsula is utmost important to improve forecast accuracy on the weather systems moving into Korea through the seas. Observations of sand dust storm in the domestic and the source regions are also essential. Such various IOPs should serve as important components of international field campaign such as THORPEX (THe Observing system Research and Predictability EXperiment) through active international collaborations.

An Investigation of the deformation of underground excavations in slat and potash mines

  • Kwon, Sang-Ki
    • Proceedings of the Korean Geotechical Society Conference
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    • 1998.05a
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    • pp.83-114
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    • 1998
  • The most widely accepted method for understanding the deformation mechanism of rock is from the use of computer simulation. However, if the changes in rock properties after excavation are significant this will prevent the computer simulation kent predicting the deformation with acceptable accuracy. If the deformations are, however, carefully measured in situ, the resulting data can be more useful far predicting the deformational behavior of underground openings, since the effect of the parameters which influence the deformational behavior are included in the measurement. In this study, extensive data analyses were carried out using the deformation measurements from the Waste Isolation Pilot Plant (WIPP), which is a permanent nuclear waste repository The results from computer simulations were compared with field measurements to evaluate the assumptions used in the computer simulations, For better description of the deformational behavior around underground excavations, several techniques were developed, namely: (a) the calculation of the zero strain boundary; (b) the evaluation of the influence of adjacent excavations on the deformational behavior of pre-excavated openings; (c) the description of the deformational behavior using in situ measurements; (d) the calculation of the shear stress distribution; and (e) the application of a Neural Network for the prediction of opening deformation.

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