• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.77-77
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• 2020

Purple loosestrife-Lythrum anceps (Koehne) Makino is a herbaceous perennial plant belonging to the Lythraceae family. It has been used for centuries in Korea and other Asian traditional medicine. It has been showed pharmacological effects, including anti-oxidant and anti-microbial effects. However, the mechanisms underlying its anti-cancer mechanisms are not yet understood. In this study, we investigated the mechanism of apoptosis signaling pathways by ethanol extract of Lythrum anceps (Koehne) Makino (ELM) in human leukemia U937 cells. Treatment with ELM significantly inhibited cell growth in a dose-dependent manner by inducing apoptosis, as evidenced by the formation of apoptotic bodies (ApoBDs), DNA fragmentation and increased populations of sub-G1 ratio. Induction of apoptosis by ELM was connected with up-regulation of death receptor (DR) 4 and DR5, pro-apoptotic Bax protein expression and down-regulation of anti-apoptotic Bcl-2 protein, and inhibitor of apoptosis protein (IAP) family proteins (XIAP, cIAP-1, survivin), depending on dosage. This induction was associated with Bid truncation, mitochondrial dysfunction, proteolytic activation of caspases (-3, -8 and -9) and cleavage of poly(ADP-ribose) polymerase protein. Therefore, our data indicate that ELM suppresses U937 cell growth by activating the intrinsic and extrinsic apoptosis pathways, and thus may have applications as a potential source for an anti-leukemic chemotherapeutic agent.

• 대한가정학회:학술대회논문집
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• 대한가정학회 1997년도 Program & Abstracts * The 7th Korea-Japan Home Economics Joint Syposium
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• pp.273-273
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• 1997

• 대한가정학회:학술대회논문집
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• 대한가정학회 1997년도 Program & Abstracts * The 7th Korea-Japan Home Economics Joint Syposium
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• pp.265-265
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• 1997

• 가정과삶의질연구
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• 제30권5호
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• pp.1-15
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• 2012

The purpose of this study is various discussion and alternatives focusing on integration of center for enhancing family policy delivery system and family support service the long term. The subject is managers who work at Healthy Family Support centers and Multicultural Family Centers. And they are responded non-structural questionnaire. The results were follows: First, 82.4% respondents of healthy support center and 50% respondents were in favor of integration. Second, reason of integration are conformance for social integration, the efficiency of center operations, the adequacy of program for various family, doing program with the goal of both centers of the similarity, complementary, and user convenience, prevent duplication and missing of services and so on, If the amount charged against the project of the center dissimilarity of institutions, including the operating direction was different. Third, the Center for the meaning of integration are name, organization, reorganization or consolidation of functions, was regarded as entrusted to corporate consolidation. Fourth, the consolidation that occurs during problem solving to ensure the succession of budgeting and human resources and program alternative for dressing up, commissioning center was the difference as problem solving.

• 한국어류학회지
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• 제19권1호
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• pp.73-80
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• 2007

한국 남해안에서 저층 트롤로 채집된 가자미목 어류 3종을 표본에 근거하여 재기재하였다. Samaridae (국명신칭: 신월가자미과)에 속하는 Samariscus japonicus (표준체장 73.4 mm 1개체)는 유안측에 5개의 가슴지느러미 연조를 가지고 무안측에는 가슴지느러미가 없다. 같은 과의 Plagiopsetta glossa (표준체장 53.6~125.8 mm 20개체)는 유안측은 흑갈색이고 가슴지느러미 연조가 8~10개이며, 6개의 고리 모양의 검은 반점이 있다. 또한 납서대과에 속하는 Aseraggodes kaianus (표준체장 74.1~83.4 mm 3개체)는 유안측의 몸과 지느러미에 흑갈색 그물무늬가 있는 것이 특징이다.

• 가족자원경영과 정책
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• 제17권2호
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• pp.173-194
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• 2013

The purpose of this study was to examine the association between time-income availability and health-promoting behavior (physical practice, smoking, alcohol consumption) of older males (55-69). This study attempted to shed light on health-behavior changes during the transition period of male retirement. The availability of time resources was examined by addressing the amount of weekly paid labor hours. The availability of financial resources was calculated by using the debt-income ratio. The study sample comprised 1,372 (age range 55-69) male respondents of the 2006 Korean Longitudinal Study of Aging (2006 KLOSA wave 1). The results of CHAID (CHi-squared Automatic Interaction Detection) analysis uncovered four distinctive combinations of resource types: time-money poor, time rich, money rich, time-money rich. According to logit results, these four groups had different socio-demographic profiles and different health-behavior risks. The time-money poor males were unlikely to perform physical activities needed to improve their health or to quit smoking or alcohol consumption. This group was also more likely to consume alcohol compared to the time-money resource types. In contrast, the time-money rich group was more likely to exercise longer and more frequently than the reference group (time and money poor). The time-rich types, those who have time-only resources and less money, were likely to be smokers and have problems with alcohol consumption.

• International Journal of Industrial Entomology and Biomaterials
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• 제9권1호
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• pp.149-153
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• 2004

Here we report the molecular cloning of a LIM protein cDNA of the CRP (cysteine-rich protein) family from the mulberry longicorn beetle, Apriona, geramri. The A. germari LIM protein cDNA contains an open reading frame of 276 bp encoding 92 amino acid residues with a calculated molecular weight of approximately 10 kDa. The A. germari LIM protein contains the cysteine-rich consensus sequence of LIM domain and the glycine-rich consensus sequence observed in cysteine-rich protein family 1 (CRP1). The potential nuclear targeting signal is retained. The deduced amino acid sequence of the A. germari LIM protein cDNA showed 81 % identity to both Bombyx mori muscle LIM protein (Mlp) and Drosophila melanogaster Mlp60A and 77% to Epiblema scudderiana Mlp. Northern blot analysis showed that A. germari LIM protein is highly expressed in epidermis and muscle, and less strongly in midgut, but not in the fat body.

• 가정∙방문간호학회지
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• 제10권1호
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• pp.58-72
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• 2003

The purpose of this study was to describe the perceived burden of the terminally III patients's caregiver and to analyze relationship between the perceived burden and the various demographics, illness characteristics, family relationships, and economic factor of the family & patients. The sample of 132 caregivers who care for the terminally III patients Kyung-Gi province, Seoul, Korea. The period of this study was from August to September, 2002. The perceived burden of the family caregiver was measured by the burden scale(20 items, 4 point scale) developed by Montgomery et al. (1985). The Data was analyzed using SAS-program by t-test and ANOVA. The results were as follows; 1. The mean of the family caregiver's burden score was 3.02. The score showed that caregivers perceive severe the level of burden. The hight items of the family caregiver's burden were' I feel it is painful to watch patient's diseases'(3.77). 'I feel afraid for what the future holds for my patients'(3.66), 'I feel it reduced to amount of privacy time'(3.64). 2. The caregiver's burden was significantly related to patient's gender(F=3.17, p= 0.0020), patient's job(F=2.49, p=0.0476), caregiver's age(F=4.29, p=0.0030), and caregiver's job(F=2.49, p=0.0476). 3. The caregiver's burden according to illness characteristics showed no significant difference. 4. The caregiver's burden was significantly associated with patient's family relationship (F=4.05, p=0.0041), patient's care mean period in a day(F=47.18,

• 가족자원경영과 정책
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• 제14권4호
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• pp.77-100
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• 2010

Locals' initiating the community making projects is considered as a good approach in terms of the effectiveness, sustainability and government's budget. But there are not the local institutions' support, while local people alone may face difficulties in starting and managing the projects. This study is to explore the roles of the institutions for starting and managing the family-friendly communities. For this purpose, 18 secondary source cases from the livable community making projects were analyzed. And the major findings of this study were as follows: The (local) institutions need to gain credibility from the locals before starting the family-friendly community project. In the motivation steps, the institution performs the role of a proposer, a survey researcher, an opinion gatherer and mediator. In the systematization steps, the institution needs to perform as a mentor, a developer of human and non-human resources, a conflict mediator, an education practitioner, an instructor, a networker, and an administrative staff. In the execution steps, the institution needs to perform as a cultural program planner, a public relations personnel, and an assessor. In conclusion, the institution needs to train community coordinator and develop programs to educate local residents for the effective family-friendly community projects.

• 한국지역사회생활과학회지
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• 제27권3호
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• pp.387-403
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• 2016

This study explored the relationships between unmarried adult children and their coresident parents with a focus on the role of intergenerational exchanges and family values affecting parent-child relations. A total of 767 unmarried adult children who lived with their parents were selected from the data of the third National Korean Family Survey in 2015. The main findings were that coresident adult children exchange diverse resources with their parents and that exchange patterns whether receiving more or giving more differed depending on the helping dimensions. 'Receiving' type was more prominent in the dimension of practical help, while, 'receiving and giving' type was more noticeable in the dimension of emotional help. Findings also suggest that intergenerational exchange and family values contribute to parent-child relationship quality. While being an active provider of practical help is positively associated with relationship quality, being a recipient of emotional help is related to a higher level of relationship quality compared to being indifferent. In addition, a stronger value of family responsibility was associated with a higher level of relationship quality. These findings indicate that the importance of the practical and emotional component in the relationships between unmarried adult children and their co-resident parents and reciprocal intergenerational exchange and strong family values may be contributory factors to better parent-child relationships.