• Journal of the Korean Data and Information Science Society
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• v.26 no.2
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• pp.367-376
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• 2015

Today, big data has become a hot keyword in that big data may be defined as collection of data sets so huge and complex that it becomes difficult to process by traditional methods. Clustering method is to identify the information in a big database by assigning a set of objects into the clusters so that the objects in the same cluster are more similar to each other clusters. The similarity measures being used in the cluster analysis may be classified into various types depending on the nature of the data. In this paper, we computed upper and lower limits for probability interestingness measure based similarity measures without marginal probability such as Yule I and II, Michael, Digby, Baulieu, and Dispersion measure. And we compared these measures by real data and simulated experiment. By Warrens (2008), Coefficients with the same quantities in the numerator and denominator, that are bounded, and are close to each other in the ordering, are likely to be more similar. Thus, results on bounds provide means of classifying various measures. Also, knowing which coefficients are similar provides insight into the stability of a given algorithm.

• Tuberculosis and Respiratory Diseases
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• v.60 no.3
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• pp.290-296
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• 2006

Background : IS6110 DNA fingerprint is a very useful tool for investigating the transmission of tuberculosis. The aim of this study was to identify the epidemiological situations within a given area (one province). Methods : The 681 Mycbobacterium tuberculosis isolates from patients, who were registered at health centers in Gyeonggi Province from May to December in 2004, were subjected to IS6110 DNA fingerprinting. Patients belonging to clusters were interviewed by health-workers to determine their previous contacts or household TB history. Results : The number of IS6110 copies of the 681 isolates showed diverse fingerprint patterns from 0 to 21 of which the most prevalent copy number was 10 from 120 isolates (17.6%). Thirty-three isolates (4.8%) belonged to the K strain, and 128 isolates (18.8%) belonged to the K family. There were 180 (26.4%) isolates belonged belonging to fifty clusters, of which two clusters were within household transmission. Forty-three (23.9%) out of 180 patients resided in an area under the same health center control. The rate of clusters in those aged 60-70 was higher than in any other age group ( 95% CI of RR : 1.072 ~ 1.988). Conclusion : This is the first report of an epidemiological survey based on a whole province using a DNA fingerprinting technique for M. tuberculosis. These results will be helpful in developing a program or policies to prevent the transmission of TB.

• Child Health Nursing Research
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• v.7 no.4
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• pp.421-433
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• 2001

The purpose of this phenomenological study was to understand the lived experience of mothers of children with muscular dystrophy. The participants were 11 mothers recruited by snowball sampling, who agreed with the objectives of the research and could verbally communicate with the researcher and who lived with their sons who had muscular dystrophy. Data collection was done through in-depth interviews with participants in their own homes. Each interview took 50 to 120 minutes. All of the interviews were audiotaped and then transcribed. Data were analyzed using Colaizzi's (1978) method of phenomenology. From the transcripts 109 significant sentences and phrases were selected and 13 clusters of themes were categorized from 67 significant statements. These results were integrated into the essential structure of the lived experience of mothers of children with muscular dystrophy. 1. Anxious and relying on chance due to indefinite diagnosis. 2. Only able to cry with shock because of son's fatal disease. 3. Seeing the future as dismal and feeling resentment that this disease in transmitted through the mother. 4. Feeling caught between a husband who is distancing himself from his family and the family which is disintegrating. 5. Feeling like a sinner for transmission of genetic disease(Feeling guilt for conceiving a son with a genetically transmitted fatal disease). 6. Empathizing with other suffers of muscular dystropy and their parents in their grief and helping to dissipate their heavy feelings. 7. Deciding to sacrifice self as a way of taking responsibility for giving birth to a handi-capped son. 8. Losing hope (feeling despair) as son's condition deteriorates in spite of all attempts to help him. 9. Wishing to die with son who becomes progressively immobile. 10. Accumulating Han*(한, 恨), because of rising Hwa(화, anger), and becoming sick both mentally and physically. 11. Seeing events as destiny and finding self-control through faith. 12. Finally, giving up sacrificing self for son and becoming concerned(involved) with other children in the family. 13. Feeling fear at son's impending death. This is the first research on the experience of Korean mothers of children with muscular dystrophy. In applying the phenomenology research method, this study not only helps health professionals understand the experience of these mothers in the Korean patriarchal social system, but the researcher, as a nurse, can share their agony and grief through identification of their inner world through in-depth personal interviews. The results obtained in this study will not only help in the development of family nursing practice for families with genetically transmitted diseases but also prepare basic data for family nursing practice in the Korean sociocultural context.

• Journal of Korean Home Economics Education Association
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• v.27 no.2
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• pp.35-51
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• 2015

The purpose of the present study is to investigate the various reasons that might lead single women to choose not to marry. Semi-structured in-depth interviews were arranged with 18 single women who met the criteria for the present research purpose. We considered only those responses of the interviewees that are directly related to their reasons why they choose not to marry, where the collected data were analyzed in three steps by methods of thematic analysis. As a result of the analysis, the reasons for which they chose not to marry could be grouped into three main clusters of themes which may be labeled as (1) themes centered on 'Myself', (2) themes centered on 'Family' and (3) themes centered on 'Surrounding Environments and Friends'. Among the first category of themes of 'Myself', we have found five sub-themes such as "Lack of emotional communication", "Not-found spouse meeting my criteria", "My personality", "Self-narcissism or self-centeredness", "False beliefs in marriage". As for the second category of themes 'Family', three sub-themes have been found including "Family of origin conflict", "Closeness to family of origin", "Comfortable daily lives". And for the final category of themes 'Surrounding Environments and Friends', there were found three sub-themes which include "Negative effects of married friends", "Emotional support system", "Changing social atmosphere". In all there are eleven sub-themes to consider. On the basis of these results, we presented some conclusions on the reasons why single women in their thirties or forties choose not to marry. We also presented some implications of these results on population education and future research.

• Journal of Family Resource Management and Policy Review
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• v.19 no.2
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• pp.127-148
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• 2015

This study compared types of time and money attitudes by respondents' characteristics, and compared leisure consumption behavior and leisure satisfaction among different groups, which are classified by attitudes toward time and money. It also verified a structural model for the relationship of leisure satisfaction and the attitudes toward time and money, and investigated the moderating effects of leisure consumption behavior. Data were obtained from a questionnaire completed by 512 adult consumers. Using factor analyses and cluster analyses, this study classified the types of time and money attitudes. The time attitude was categorized according to four clusters: time-insensibility, future- oriented, present-oriented, and past-oriented. The money attitude was divided into four clusters: future safety, stinginess/anxiety, diversion, and power/prestige. The major findings of this study were as follows: First, the propensity of leisure consumption behavior to seek fashion and conspicuousness was higher for time-insensibility group than for the others. However, the propensity of rational consumption behavior for leisure was higher for the future-oriented group. The level of leisure satisfaction was the highest for the time-insensibility group. Second, the propensity of leisure consumption behavior to seek fashion and conspicuousness was higher for those who considered money as tools for diversion and power/prestige. The propensity of rational consumption behavior for leisure was higher for the future safety and stinginess/anxiety groups. The level of leisure satisfaction was significantly higher for the diversion group. Third, from the results of structural analyses, the time-insensibility attitude showed a positive effect on the leisure consumption behavior to seek fashion and conspicuousness. The future-oriented attitude had a positive effect on the propensity of rational consumption behavior for leisure. The money attitudes of diversion and power/prestige had positive impacts on the leisure consumption behavior to seek fashion and conspicuousness, although they had negative effects on the propensity of rational consumption behavior for leisure. The leisure consumption behavior to seek fashion and conspicuousness had a positive effect on leisure satisfaction, although the rational consumption behavior for leisure had a negative effect.

• Journal of Life Science
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• v.13 no.5
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• pp.723-731
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• 2003

For the investigation of conserved regions in lipase genes, 132 and 24 sequences were obtained from LED (Lipase Engineering Database) and COG (Clusters of Orthologous Groups of proteins), respectively. There was high diversity in lipase genes and peculiar amino acid sequences were conserved for each homologous family of LED. Similar conserved amino acid sequences were detected from COG0657 and Moraxella lipase 1 homologous group of LED. Although many studies have attempted to detect new lipase genes in procaryotes, they have been limited culturable bacteria. The importance of metagenome, including DNA from non-culturable bacteria, is known. Due to the high diversity, we assumed it might be possible to detect new lipase gene from metagenome. Due to the high diversity of nucleotide sequences in lipase genes, 10 primer sets were designed. Designed primer sets were inspected in BLAST of NCBI and they could amplify a part of the lipase gene from 222 to 713 bp. They can amplify 16.7%∼60.0% of each lipase homologous group which was 3.6 fold higher than each sets. They might offer a high probability of detecting new lipase genes, owing to high efficiency and the diversity of lipase genes.

• Korean Journal of Social Welfare
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• v.58 no.1
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• pp.373-393
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• 2006

This study aimed at understanding the experience in deciding for childcare of unmarried lone mother and searching for intervention methods through in-depth examination of the essence of the experience. To achieve this, the Colazzi analysis of phenomenological research was applied. The subjects of study were 7 unmarried lone mothers in early age of the twenties and thirties, who resided in an institution for unmarried lone mothers. An in-depth interview was held individually with them with question of "What is the experience in deciding for childcare as a unmarried lone mother" twice on the average from Nov. 2003 to Feb. 2005. The results found that a unmarried lone mothers' experience in childcare meant 'resurrection' through analyzing 22 themes and 7 theme clusters(confusion due to pregnancy, harsh feeling for reality suffering alone, feeling of love for a baby, mental conflict about childcare, decision toward childcare, firm in decision, hope for resurrection). Although the results of this study have the limitation of generalization due to phenomenological study, it will contribute to accepting and understanding mother-and-child families as one type of family rather than regarding them as being difficult or alienated in family and society, to recognizing the need of taking back their rights, and to suggesting intervention methods for unmarried lone mothers.

• Journal of Korean Home Economics Education Association
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• v.29 no.1
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• pp.71-92
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• 2017

The purpose of the present study is to investigate the experiences of original family and social relationships in single women. Semi-structured in-depth interviews were arranged with 18 single women who met the criteria for the present research purpose. We considered only those responses of the interviewees that are directly related to their experiences of original family and social relationships, where the collected data were analyzed in three steps by methods of thematic analysis. As a result of the analysis, the experiences of original family and social relationships in single women could be grouped into six main clusters of themes which may be labeled as (1) themes centered on 'Family attachment', (2) themes centered on 'Special People' and (3) themes centered on 'Estrange relative relationship'. (4) themes centered on 'Small social life', (5) themes centered on 'Absence of a social relationshipship', (6) themes centered on 'Drive for freedom'. Among the first category of themes of 'Family attachment', we have found three sub-themes such as 'Adult Baby under parents' care', 'Confirm of single life', 'Intricate family relations'. As for the second category of themes 'Special People', three sub-themes have been found including 'I Only Love Mom.', 'Sister friend', 'My lovely nephew or niece'. And for the third category of only one theme 'Estranged relative relationship'. And for the fourth category of themes 'Small social life', there were found four sub-themes which include 'Relationship at work', 'Chat with friends', 'Keep oneself aloof from the opposite sex', 'Singles gather together'. And for the fifth category of themes 'Absence of a social relationshipship', there were found three sub-themes which include 'Alone than meeting', 'Lazism', 'Tight daily lives'. And for the final category of themes 'Drive for freedom', there were found two sub-themes which include 'Caution for attachment', 'Caution for entanglement'. In all, there are sixteen sub-themes to consider. On the basis of these results, we presented some conclusions on the experiences of original family and social relationships in single women. We also presented some implications of these results on population education and future research.

• Journal of Microbiology and Biotechnology
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• v.24 no.12
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• pp.1644-1653
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• 2014

Wuyiencin is produced by Streptomyces ahygroscopicus var. wuyiensis CK-15 and is widely used as an antifungal agent in agriculture. Analysis of wuyiencin biosynthetic gene clusters reveals wysR, a member of the LAL-family of transcriptional regulatory genes. WysR consists of an N-terminal PAS domain and a LuxR family C-terminal helix-turn-helix motif. However, the roles of wysR in wuyiencin biosynthesis are largely unknown. In this study, we showed that inactivation of wysR resulted in the complete loss of wuyiencin production, which could be restored by complementation with a single copy of wysR. Furthermore, we successfully increased wuyiencin production to a significantly higher level by overexpression of wysR in S. wuyiensis CK-15. Quantitative real-time RT-PCR analysis showed that WysR regulates wuyiencin biosynthesis by modulating other putative regulatory genes. Thus, WysR was identified as an activator of wuyiencin biosynthesis, and overexpression of wysR gene proved to be an effective strategy for improving wuyiencin production.

• Korean Journal of Human Ecology
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• v.20 no.2
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• pp.365-376
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• 2011

This paper measured elderly consumers' perceptions of purchasing problems, and classified elderly consumers into 5 categories of purchasing problems using cluster analysis, and analyzed the relationships between the elderly consumers' perception type, socio economic variables, activities of daily living, and activities of healthy living. The data was collected from 500 elderly consumers in Ulsan Metropolitan City. Three clusters were extracted. 56.4% of the sample was included in 'redress and contract problems group', and 22.6% of the sample was included in 'less perception of purchasing problems group, and 21.0% of the sample was included in 'the perception of strong purchasing problems group. The elderly consumers' perception type of purchasing problems were related with socio-economic variables such as sex, existence of a spouse, the number of family living together, the number of children, education, the average monthly household income and allowance, activities of daily living, and activities of healthy living. The redress and contract problems group was found to be of midium level in socio-economic and health status, and included more females and less spouselessness. The perception of less purchasing problems group was found to be the highest level in socio-economic status, and included more males and less spouselessness. The perception of strong purchasing problems group was found to be at the lowest level of socio-economic status.