• Korean Journal of Oriental Medicine
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• v.13 no.2 s.20
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• pp.121-125
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• 2007

Background and Purpose : The purpose of this study was done to investigate what kinds of statistical techniques have been used to analyze data from oriental medicine research Methods : 135 original articles which used statistical techniques in their data analysis were selected from the articles published in The Journal of Korea Institute of Oriental Medicine(JKIOM) between 1995 to 2007. Results : Among 135 articles, 59 articles used descriptive statistics while 76 articles used inferential statistics for data analysis. For that 76 articles, two-sample t-test(33 articles), analysis of variance(29 articles), regression(9 articles), chi-square test(5 articles), nonparametic test(4 articles), Fisher's exact test(3 articles), and other test(9 articles) were chosen to analyze the data. SAS and SPSS statistical softwares(82.50%) were mostly used to analyze the data. Nonparametic tests were used to 4 articles(6.97%) of 67 articles and parametic tests were used to 63 articles(93.03%) of 67 articles. Among 29 articles used analysis of variance, duncan(8 articles), dunnet(4 articles), bonferroni(4 articles), turkey(3 articles), scheff(1 article) were used to do multiple comparison. 9 articles did not carry out the multiple comparison. Conclusions : It was found that the frequencies of statistical package used and statistical analysis used were not much by now. High level statistical analyses were not used most for oriental medicine research.

• The Korean Journal of Pain
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• v.13 no.1
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• pp.60-66
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• 2000

Background: For terminal cancer pain management, controlled-release oral morphine (morphine sulfate tablet, MST) is a simple and convenient regimen. Recently, fentanyl transdermal therapeutic system (F-TTS, transdermal fentanyl) has been developed and became one of the alternative ways of providing adequate pain relief. This open prospective study was designed to compare the analgesic efficacy and safety of MST and transdermal fentanyl in the management of terminal cancer pain. Methods: In this open comparative and randomized study, 64 terminal cancer patients received one treatment for 15 days, controlled-release oral morphine (MST group) or fentanyl transdermal therapeutic system (F-TTS group). Daily diaries about the vital sign, visual analogue scale (VAS) for pain, opioids requirement, co-anagesics, adjuvant drugs and adverse effects were completed with 24 patients in MST group, 18 patients in F-TTS group. Results: The majority of patients in both treatment groups were late-stage cancer and their distribution was not different in both groups. Daily opioids requirement was 126.4 mg in MST uced in F-TTS group (P<0.05). The incidence of nausea, vomiting and constipation was lower in F-TTS group (P<0.05). Patients satisfaction was similar, but F-TTS patient group favored continous use of same treatment compared with MST group after the study was finished. Conclusions: Transdermal fentanyl seems to be safe and similar analgesic effect to controlled-release oral morphine for the control of the terminal cancer patients. However, transdermal fentanyl provides a simpler and more convenient especially in respect to constipation, nausea & vomiting. To determine the exact analgesic effect, cost-effectiveness and complications, controlled trials should be followed.

• Journal of Korean Public Health Nursing
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• v.25 no.1
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• pp.48-60
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• 2011

Purpose: The number of people using the internet to meet their health information needs is growing. However, little is known about the characteristics of the senior internet health information seeker. The purpose of this study was to identify the socio-demographic and health-related characteristics, as well as the internet health information seeking behaviors and attitudes in the elderly. Method: Data was collected from 385 elderly subjects(aged 55 years or older) and living in Seoul and Gyeonggi. We used questionnaires developed by researchers in this study. Data was analyzed using the following methods: descriptive statistics, t-test, $X^2$-test and Fisher's exact test. All statistical tests were performed using the SAS version 9.13. Results: The elderly using the internet to seek health information had relatively good subjective health and were living with a spouse. In general, the purpose of internet use was to search for information, and mainly used at home. The search in the disease management area was higher than the frequency of searches for health promotion. The elderly showed a generally positive attitude regarding health information. Conclusion: It is needed to increase the use of the Internet for finding health information and promote accessibility for internet health information in the elderly.

• The Journal of the Korea institute of electronic communication sciences
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• v.5 no.4
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• pp.425-434
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• 2010

This study shows a limit to attacks that the prevention system, which is used as the mutual third aggressive packet path between open heterogeneous networks and applies prevention techniques according to the trace like IP tracking and attack methods, can prevent. Therefore, the study aims to learn information of constant attack routing protocol and of the path in network, the target of attack and build a database by encapsulating networks information routing protocol operates in order to prevent source attack paths. In addition, the study is conducted to divide network routing protocols developed from the process of dividing the various attack characters and prevent various attacks. This study is meaningful in that it analyzes attack path network and attacks of each routing protocol and secure exact mechanism for prevention by means of 3D-Puzzle, Path, and Cube of the integrated security system which is an implementation method of integrated information protection for access network defense.

• The Journal of the Korea institute of electronic communication sciences
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• v.14 no.6
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• pp.1235-1240
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• 2019

It is well known that the ground water level changes rapidly before and after the earthquake, and the variation of ground water level prediction is used to predict the earthquake. In this paper, we predict the ground water level in Miryang City using ANFIS algorithm for earthquake prediction. For this purpose, this paper used precipitation and temperature acquired from National Weather Service and data of underground water level from Rural Groundwater Observation Network of Korea Rural Community Corporation which is installed in Miryang city, Gyeongsangnam-do. We measure the prediction accuracy using RMSE and MAPE calculation methods. As a result of the prediction, the periodic pattern was predicted by natural factors, but the change value of ground water level was changed by other variables such as artificial factors that was not detected. To solve this problem, it is necessary to digitize the ground water level by numerically quantifying artificial variables, and to measure the precipitation and pressure according to the exact location of the observation ball measuring the ground water level.

• Journal of Korea Multimedia Society
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• v.12 no.11
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• pp.1623-1628
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• 2009

This paper presents the development of certain highly efficient and accurate method for computing tangent curves for two-dimensional vector fields. Unlike convention methods, such as Runge-Kutta, for computing tangent curves which produce only approximations, the method developed herein produces exact values on the tangent curves based on piecewise linear variation over a triangle in 2D. This new method assumes that the vector field is piecewise linearly defined over a triangle in 2D. It is also required to decompose the rectangular cell into two triangular cells. The critical points can be easily found by solving a simple linear system for each triangle. This method is to find exit points by producing a sequence of points on the curve with the computation of each subsequent point based on the previous. Because points on the tangent curves are calculated by the explicit solution for each triangle, this new method provides correct topologies in visualizing 2D vector fields.

• Journal of Korean Neurosurgical Society
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• v.39 no.1
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• pp.46-51
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• 2006

Objective : An Intracranial aneurysm is an important acquired cerebrovascular disease that can cause a catastrophic subarachnoid hemorrhage. Atherosclerosis is one of possible mechanism, but its contribution to aneurysm formation is unclear. Human apolipoprotein E[apoE] is best known for its arterial protection from atherosclerosis. In this study we observe apoE expression in experimental cerebral aneurysms of rats to elucidate the role of apoE in the process of cerebral aneurysm formation. Methods : Twenty-four male 7-week-old Sprague-Dawley strain rats received a cerebral aneurysm induction procedure. One month[12] and three months[12] after the operation, the rats were killed, their cerebral arteries were dissected, and the regions of the bifurcation of the right anterior cerebral artery-olfactory artery [ACA-OA] bifurcations were examined histologically and immunohistochemically. Results : In the 1 month group [n=12], the ACA-OA bifurcation showed no aneurysmal change in 7 rats and early aneurysmal change in 5 rats. In the 3 months group (n=12), the bifurcation showed no aneurysmal change in 2 rats and an advanced aneurysm in 10 rats. ApoE expression were in 3 specimen in early aneurysmal change, but not in advanced aneurysms. Conclusion : ApoE expression in early aneurysmal wall suggests a possible role for apoE in early events leading to aneurysm formation. Further studios are necessary to elucidate the exact role of apoE in the pathophysiology of cerebral aneurysm.

• Journal of Korean Neurosurgical Society
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• v.30 no.4
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• pp.425-429
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• 2001

Objective : Patients with poor grade aneurysm usually present with increased intracranial pressure(ICP), even those without an intracranial clot. Based on this fact, the present study investigated a significance of intracranial pressure monitoring in those patients. Patients and Methods : A total of 60 patients with Hunt and Hess Grade IV(50 patients) or V(10 patients) were treated for aneurysmal subarachnoid hemorrhage(SAH) during a 3-year-period, and intraparenchymal ICP was measured in the majority, immediately after arrival to the emergency room. Early surgery including intraoperative ventriculostomy was undertaken within 3 days after SAH. An ultraearly surgery was performed without preceding angiogram or ICP monitoring in patients with large sylvian hematomas, highly suggestive of middle cerebral artery aneurysm. Outcomes were assessed by the Glasgow Outcome Scale(GOS) at 6 months. Results : In overall, favorable outcome(GOS scores 1-2) was seen in 27(54.0%) of admission Grade IV and 1(10.0%) of admission Grade V patients. Of the 38 surgical patients with preoperative ICP monitorings, 25 patients (80.6%) exhibiting ICP values of less than 40mmHg showed favorable outcome, however, no patients with ICP values above 40mmHg recovered(Fisher's exact test, p=0.0001). Conclusion : It is concluded that a preoperative ICP above 40mmHg before ventriculostomy indicate significant vital brain destruction as intractable intracranial hypertension, and Grade IV patients at admission with an ICP below 40mmHg can be of benefit from early surgical intervention while Grade V patients still remains unfavorable.

• Journal of Korean Neurosurgical Society
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• v.58 no.1
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• pp.9-13
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• 2015

Objective : To improve pedicle screw placement accuracy with minimal radiation and low cost, we developed specially designed K-wire with a marker. To evaluate the accuracy of thoracolumbar pedicle screws placed using the novel guide-pin and portable X-rays. Methods : Observational cohort study with computerized tomography (CT) analysis of in vivo and in vitro pedicle screw placement. Postoperative CT scans of 183 titanium pedicle screws (85 lumbar and 98 thoracic from T1 to L5) placed into 2 cadavers and 18 patients were assessed. A specially designed guide-pin with a marker was inserted into the pedicle to identify the correct starting point (2 mm lateral to the center of the pedicle) and aiming point (center of the pedicle isthmus) in posteroanterior and lateral X-rays. After radiographically confirming the exact starting and aiming points desired, a gearshift was inserted into the pedicle from the starting point into the vertebral body through the center of pedicle isthmus. Results : Ninety-nine percent (181/183) of screws were contained within the pedicle (total 183 pedicle screws : 98 thoracic pedicle screws and 85 lumbar screws). Only two of 183 (1.0%) thoracic pedicle screws demonstrated breach (1 lateral in a patient and 1 medial in a cadaver specimen). None of the pedicle breaches were associated with neurologic or other clinical sequelae. Conclusion : A simple, specially designed guide-pin with portable X-rays can provide correct starting and aiming points and allows for accurate pedicle screw placement without preoperative CT scan and intraoperative fluoroscopic assistance.

• Journal of Korean Neurosurgical Society
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• v.53 no.2
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• pp.72-76
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• 2013

Objective : Cerebral aneurysm (CA) is an important acquired cerebrovascular disease that can cause catastrophic results. MicroRNAs (miRNAs) are small non-coding RNAs, playing essential roles in modulating basic physiologic and pathological processes. Currently, evidences have been established about biologic relationship between miRNAs and abdominal aortic aneurysms. However, biologic roles of miRNAs in CA formation have not been explained yet. We employed microarray analysis to detect and compare miRNA expression profiles in late stage of CA in rat model. Methods : Twenty-six, 7-week-old male Sprague-Dawley rats underwent a CA induction procedure. The control animals (n=11) were fed a normal diet, and the experimental animals (n=26) were fed a normal diet with 1% normal saline for 3 months. Then, the rats were sacrificed, their cerebral arteries were dissected, and the five regions of aneurysmal dilation on the left posterior communicating artery were cut for miRNA microarrays analysis. Six miRNAs (miRNA-1, miRNA-223, miRNA-24-1-5p, miRNA-551b, miRNA-433, and miRNA-489) were randomly chosen for validation using real-time quantitative PCR. Results : Among a set of differentially expressed miRNAs, 14 miRNAs were over-expressed more than 200% and 6 miRNAs were down-expressed lower than 50% in the CA tissues. Conclusion : The results show that miRNAs might take part in CA formation probably by affecting multiple target genes and signaling pathways. Further investigations to identify the exact roles of these miRNAs in CA formation are required.