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Development and validation of prediction equations for the assessment of muscle or fat mass using anthropometric measurements, serum creatinine level, and lifestyle factors among Korean adults

  • Lee, Gyeongsil;Chang, Jooyoung;Hwang, Seung-sik;Son, Joung Sik;Park, Sang Min
    • Nutrition Research and Practice
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    • v.15 no.1
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    • pp.95-105
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    • 2021
  • BACKGROUND/OBJECTIVES: The measurement of body composition, including muscle and fat mass, remains challenging in large epidemiological studies due to time constraint and cost when using accurate modalities. Therefore, this study aimed to develop and validate prediction equations according to sex to measure lean body mass (LBM), appendicular skeletal muscle mass (ASM), and body fat mass (BFM) using anthropometric measurement, serum creatinine level, and lifestyle factors as independent variables and dual-energy X-ray absorptiometry as the reference method. SUBJECTS/METHODS: A sample of the Korean general adult population (men: 7,599; women: 10,009) from the Korean National Health and Nutrition Examination Survey 2008-2011 was included in this study. The participants were divided into the derivation and validation groups via a random number generator (with a ratio of 70:30). The prediction equations were developed using a series of multivariable linear regressions and validated using the Bland-Altman plot and intraclass correlation coefficient (ICC). RESULTS: The initial and practical equations that included age, height, weight, and waist circumference had a different predictive ability for LBM (men: R2 = 0.85, standard error of estimate [SEE] = 2.7 kg; women: R2 = 0.78, SEE = 2.2 kg), ASM (men: R2 = 0.81, SEE = 1.6 kg; women: R2 = 0.71, SEE = 1.2 kg), and BFM (men: R2 = 0.74, SEE = 2.7 kg; women: R2 = 0.83, SEE = 2.2 kg) according to sex. Compared with the first prediction equation, the addition of other factors, including serum creatinine level, physical activity, smoking status, and alcohol use, resulted in an R2 that is higher by 0.01 and SEE that is lower by 0.1. CONCLUSIONS: All equations had low bias, moderate agreement based on the Bland-Altman plot, and high ICC, and this result showed that these equations can be further applied to other epidemiologic studies.

Linear Energy Transfer Dependence Correction of Spread-Out Bragg Peak Measured by EBT3 Film for Dynamically Scanned Proton Beams

  • Lee, Moonhee;Ahn, Sunghwan;Cheon, Wonjoong;Han, Youngyih
    • Progress in Medical Physics
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    • v.31 no.4
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    • pp.135-144
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    • 2020
  • Purpose: Gafchromic films for proton dosimetry are dependent on linear energy transfers (LETs), resulting in dose underestimation for high LETs. Despite efforts to resolve this problem for single-energy beams, there remains a need to do so for multi-energy beams. Here, a bimolecular reaction model was applied to correct the under-response of spread-out Bragg peaks (SOBPs). Methods: For depth-dose measurements, a Gafchromic EBT3 film was positioned in water perpendicular to the ground. The gantry was rotated at 15° to avoid disturbances in the beam path. A set of films was exposed to a uniformly scanned 112-MeV pristine proton beam with six different dose intensities, ranging from 0.373 to 4.865 Gy, at a 2-cm depth. Another set of films was irradiated with SOBPs with maximum energies of 110, 150, and 190 MeV having modulation widths of 5.39, 4.27, and 5.34 cm, respectively. The correction function was obtained using 150.8-MeV SOBP data. The LET of the SOBP was then analytically calculated. Finally, the model was validated for a uniform cubic dose distribution and compared with multilayered ionization chamber data. Results: The dose error in the plateau region was within 4% when normalized with the maximum dose. The discrepancy of the range was <1 mm for all measured energies. The highest errors occurred at 70 MeV owing to the steep gradient with the narrowest Bragg peak. Conclusions: With bimolecular model-based correction, an EBT3 film can be used to accurately verify the depth dose of scanned proton beams and could potentially be used to evaluate the depth-dose distribution for patient plans.

A Study on the Validity of a Contract to Expand the Grounds for Vacating Awards in Arbitration Agreements - With Special Reference to the Cases and Theories in the United States - (중재판정 취소사유를 확장한 중재합의의 효력에 관한 고찰 - 미국에서의 논의를 중심으로-)

  • Kang, Soo-Mi
    • Journal of Arbitration Studies
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    • v.32 no.1
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    • pp.43-69
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    • 2022
  • In the case of the United States, which has the same provision as Article 10 of the Federal Arbitration Act, a contract may be exceptionally validated if the parties have clearly concluded the contract to expand the grounds for vacating awards in an arbitration agreement. It is possible that the parties create the grounds for vacating that is not stipulated in the statue by clear agreement. However, it remains the issues when this contract is valid. If we investigate the grounds for setting aside as discussed in this paper, in cases ① where an arbitrator failed to apply the substantive law expressly designated by the parties without a good reason; ② where there was a serious error in the application of the substantive law; ③ where an arbitrator decided under ex aequo et bono despite the parties explicitly designated the substantive law, the parties may bring an action for annulment of arbitral awards in court according to their agreement to expand the grounds for vacating the awards. It is important enough to change the rights and obligations of the parties for them whether or not the substantive law of the arbitration was applied. With Regard to the contract to expand the grounds for setting aside the awards in arbitration agreement, there are still issues how to handle the case where the parties have not designated the substantive law, and the validity of a contract to expand the grounds for vacating on reasons other than violation of law application, and relations with Article 5 of the Convention on the Recognition and Enforcement of Foreign Arbitral Awards, where the misapplication of the law does not stipulated as the grounds for refusal to recognize and enforce the foreign arbitral award, and so on.

Association Between Cadmium Exposure and Liver Function in Adults in the United States: A Cross-sectional Study

  • Hong, Dongui;Min, Jin-Young;Min, Kyoung-Bok
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.6
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    • pp.471-480
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    • 2021
  • Objectives: Cadmium is widely used, leading to extensive environmental and occupational exposure. Unlike other organs, for which the harmful and carcinogenic effects of cadmium have been established, the hepatotoxicity of cadmium remains unclear. Some studies detected correlations between cadmium exposure and hepatotoxicity, but others concluded that they were not associated. Thus, we investigated the relationship between cadmium and liver damage in the general population. Methods: In total, 11 838 adult participants from National Health and Nutrition Examination Survey 1999-2015 were included. Urinary cadmium levels and the following liver function parameters were measured: alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transferase (GGT), total bilirubin (TB), and alkaline phosphatase (ALP). Linear and logistic regression analyses were performed to assess the associations between urinary cadmium concentrations and each liver function parameter after adjusting for age, sex, race/ethnicity, annual family income, smoking status, alcohol consumption status, physical activity, and body mass index. Results: The covariate-adjusted results of the linear regression analyses showed significant positive relationships between log-transformed urinary cadmium levels and each log-transformed liver function parameter, where beta±standard error of ALT, AST, GGT, TB, and ALP were 0.049±0.008 (p<0.001), 0.030±0.006 (p<0.001), 0.093±0.011 (p<0.001), 0.034±0.009 (p<0.001), and 0.040±0.005 (p<0.001), respectively. Logistic regression also revealed statistically significant results. The odds ratios (95% confidence intervals) of elevated ALT, AST, GGT, TB, and ALP per unit increase in log-transformed urinary cadmium concentration were 1.360 (1.210 to 1.528), 1.307 (1.149 to 1.486), 1.520 (1.357 to 1.704), 1.201 (1.003 to 1.438), and 1.568 (1.277 to 1.926), respectively. Conclusions: Chronic exposure to cadmium showed positive associations with liver damage.

Elevated plasma α1-antichymotrypsin is a biomarker candidate for malaria patients

  • Young Yil, Bahk;Sang Bong, Lee;Jong Bo, Kim;Tong-Soo, Kim;Sung-Jong, Hong;Dong Min, Kim;Sungkeun, Lee
    • BMB Reports
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    • v.55 no.11
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    • pp.571-576
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    • 2022
  • Advancements in the field of proteomics have provided opportunities to develop diagnostic and therapeutic strategies against various diseases. About half of the world's population remains at risk of malaria. Caused by protozoan parasites of the genus Plasmodium, malaria is one of the oldest and largest risk factors responsible for the global burden of infectious diseases with an estimated 3.2 billion persons at risk of infection. For epidemiological surveillance and appropriate treatment of individuals infected with Plasmodium spp., timely detection is critical. In this study, we used combinations of depletion of abundant plasma proteins, 2-dimensional gel electrophoresis (2-DE), image analysis, LC-MS/MS and western blot analysis on the plasma of healthy donors (100 individuals) and vivax and falciparum malaria patients (100 vivax malaria patients and 8 falciparum malaria patients). These analyses revealed that α1-antichymotrypsin (AACT) protein levels were elevated in vivax malaria patient plasma samples (mean fold-change ± standard error: 2.83 ± 0.11, based on band intensities), but not in plasma from patients with other mosquito-borne infectious diseases. The results of AACT immunoblot analyses showed that AACT protein was significantly elevated in vivax and falciparum malaria patient plasma samples (≥ 2-fold) compared to healthy control donor plasma samples, which has not been previously reported.

Efficient way to clean Solder Printer Nozzles

  • Kim, Young-Min;Kim, Chi-Su
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.11
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    • pp.115-121
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    • 2022
  • In surface mount technology (SMT), the screen printer, which is an equipment for applying solder cream, has a lot of poor coating as the pad becomes smaller. To solve this problem, a jet printer is being used recently. However, if the nozzle at the end of the valve applied to the jet printer head is not cleaned, solder cream remains or an error occurs. To prevent this, the nozzles should be cleaned periodically. In this paper, a more stable cleaning method than the existing technology is presented for the stable application of solder cream on a jet printer. In this method, cut a 35mm wide mujin cloth, wrap it in a roll, and rotate it with a DC geared motor on the other side to clean it. As a result, it was confirmed that the solder paste was not left on the nozzle surface and was well wiped when cleaning with about 2,000 dotting cycles.

A Novel Grasshopper Optimization-based Particle Swarm Algorithm for Effective Spectrum Sensing in Cognitive Radio Networks

  • Ashok, J;Sowmia, KR;Jayashree, K;Priya, Vijay
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.17 no.2
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    • pp.520-541
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    • 2023
  • In CRNs, SS is of utmost significance. Every CR user generates a sensing report during the training phase beneath various circumstances, and depending on a collective process, either communicates or remains silent. In the training stage, the fusion centre combines the local judgments made by CR users by a majority vote, and then returns a final conclusion to every CR user. Enough data regarding the environment, including the activity of PU and every CR's response to that activity, is acquired and sensing classes are created during the training stage. Every CR user compares their most recent sensing report to the previous sensing classes during the classification stage, and distance vectors are generated. The posterior probability of every sensing class is derived on the basis of quantitative data, and the sensing report is then classified as either signifying the presence or absence of PU. The ISVM technique is utilized to compute the quantitative variables necessary to compute the posterior probability. Here, the iterations of SVM are tuned by novel GO-PSA by combining GOA and PSO. Novel GO-PSA is developed since it overcomes the problem of computational complexity, returns minimum error, and also saves time when compared with various state-of-the-art algorithms. The dependability of every CR user is taken into consideration as these local choices are then integrated at the fusion centre utilizing an innovative decision combination technique. Depending on the collective choice, the CR users will then communicate or remain silent.

Study of Situation Prediction Simulation for Navigation Information System of Ship (선박의 항행정보시스템을 위한 상황 예측 시뮬레이션 방안 연구)

  • Yi, Mi-Ra
    • Journal of the Korea Society for Simulation
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    • v.19 no.3
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    • pp.127-135
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    • 2010
  • Modern marine navigation requires officers on the bridge to monitor a torrent of data on both the insides and outsides of the ship from numerous useful devices. But despite these tools, navigators can still find it difficult to make a safe decision for two reasons: one is that too much data if provided too quickly tends to cause fatigue and overwhelm the officer, and the other is that any inconsistency across data from several different types of devices can lead to confusion. Indeed, the fact remains that the many marine accidents can be attributed to human error, and hence there is a strong need for decision-support tools for marine navigation. One technique of providing decision support is through the use of simulation to evaluate or predict system dynamics over time using an accurate model. This paper, as a simulation method for risk prediction for a navigation safety information system of ship, suggests a navigation prediction simulation system using various knowledge bases and discrete event simulation methodology, and supports the validity of the system through the examples of components in a restricted navigation situation scenario.

Has Container Shipping Industry been Fixing Prices in Collusion?: A Korean Market Case

  • Jaewoong Yoon;Yunseok Hur
    • Journal of Korea Trade
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    • v.27 no.1
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    • pp.79-100
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    • 2023
  • Purpose - The purpose of this study is to analyze the market power of the Korea Container Shipping Market (Intra Asia, Korea-Europe, and Korea-U.S.) to verify the existence of collusion empirically, and to answer whether the joint actions of liner market participants in Korea have formed market dominance for each route. Precisely, it will be verified through the Lerner index as to whether the regional market of Asia is a monopoly, oligopoly, or perfect competition. Design/methodology - This study used a Lerner index adjusted with elasticity presented in the New Imperial Organization (NEIO) studies. NEIO refers to a series of empirical studies that estimate parameters to judge market power from industrial data. This study uses B-L empirical models by Bresnahan (1982) and Lau (1982). In addition, NEIO research data statistically contain self-regression and stability problems as price and time series data. A dynamic model following Steen and Salvanes' Error Correction Model was used to solve this problem. Findings - The empirical results are as follows. First, λ, representing market power, is nearly zero in all three markets. Second, the Korean shipping market shows low demand elasticity on average. Nevertheless, the markup is low, a characteristic that is difficult to see in other industries. Third, the Korean shipping market generally remains close to perfect competition from 2014 to 2022, but extreme market power appears in a specific period, such as COVID-19. Fourth, there was no market power in the Intra Asia market from 2008 to 2014. Originality/value - Doubts about perfect competition in the liner market continued, but there were few empirical cases. This paper confirmed that the Korea liner market is a perfect competition market. This paper is the first to implement dynamics using ECM and recursive regression to demonstrate market power in the Korean liner market by dividing the shipping market into Deep Sea and Intra Asia separately. It is also the first to prove the most controversial problems in the current shipping industry numerically and academically.

Construction Safety Training Methods and their Evaluation Approaches: A Systematic Literature Review

  • Ojha, Amit;Seagers, Jonathan;Shayesteh, Shayan;Habibnezhad, Mahmoud;Jebelli, Houtan
    • International conference on construction engineering and project management
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    • 2020.12a
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    • pp.188-197
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    • 2020
  • Due to hazardous working environments at complex, unstructured, and dynamic construction sites, workers frequently face potential safety and health risks throughout the construction process. In this regard, addressing safety challenges remains one of the top priorities. Construction workers' ability to identify and assess risks is acquired through training, which is one of the primary key factors to determine their safety and wellbeing in hazardous working environments. As such, safety managers constantly focus on the effectiveness of the training materials provided to the workers. However, the construction workers are considerably at greater risk of injuries and fatalities compared to the workers in other industries. In this regard, further studies are required to build up a body of knowledge on the conventional safety training approaches as well as their evaluation techniques in order to boost up the adoption by the practitioners in a widespread manner. This paper provides a systematic review of the current safety training approaches and the various techniques for measuring their effectiveness. The attributes of the current safety training methods for construction workers and their evaluation techniques are identified and analyzed. Results indicated that: 1) immersive environment-based training methods are effective than the traditional safety training methods; 2) this effectiveness can be empirically supported by evaluation strategies, but the current techniques are subjective, intrusive, and error-prone. This research offers fresh opportunities to investigate the training strategies by objectively monitoring the physiological responses of construction crews. The results of this study can be used by researchers and practitioners to identify and determine optimal safety training programs that could potentially become ubiquitous in the construction industry.

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