• 제목/요약/키워드: equilibrium test

검색결과 557건 처리시간 0.029초

항생제-스멕타이트 복합물 유도 및 소화기계 약물전달체로의 가능성 (Development of Antibiotic-intercalated Smectite Composites and Its Drug Delivery Potential in Gastric System)

  • 송윤구;정동훈;송영구;최우현
    • 자원환경지질
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    • 제48권3호
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    • pp.199-204
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    • 2015
  • 본 연구에서는 흡수성 항생제인 Amoxicillin과 Clarithromycin, 그리고 아미노글루코사이드 (Aminoglucoside) 계열 비흡수성 항생제인 Gentamicin, Tobramycin 및 Netilmicin의 스멕타이트 층간 유도를 통해 항생제-스멕타이트 복합물을 합성하고, 이 중 Clarithromycin-스멕타이트 복합물 대상 예비 용출실험을 통해 소화기계 항생제 약물전달체로의 가능성을 확인하고자 하였다. 실험 결과, 5종의 항생제 모두 수용액 상태에서의 교환반을을 통해 스멕타이트 층간에 유도되었다. Clarithromycin에 대하여 스멕타이트 층간 최대 유도 량을 결정하기 위한 농도별 평형반응실험 결과 Langmuir isotherm을 따르며, 층간 최대유도 량은 1.811 mmole/g으로 계산되었다. Clarithromycin-스멕타이트 복합물 대상 pH=2, 3 및 4 용출용액을 이용한 예비 용출실험결과 모든 용출용액에서 지속적인 용출이 일어났으며, pH 증가에 따라 용출량은 감소하였다.

벼의 저온건조 시뮬레이션 (Low Temperature Drying Simulation of Rough Rice)

  • 김훈;한재웅
    • Journal of Biosystems Engineering
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    • 제34권5호
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    • pp.351-357
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    • 2009
  • This study was conducted to verify the simulation model through the drying test, and investigate effect of factors, such as temperature of drying air, airflow rate, and velocity of the airflow, on the drying. The low temperature drying simulation model was developed based on the circulation dry simulation model presented by Keum et al. (1987), and by modifying low temperature thin layer drying model, equilibrium moisture content model, latent heat of vaporization model, and crack ratio prediction model. The heat pump and experimental dryer with a capacity of 150kg were used for the test. The RMSE between the predicted and measured value was 0.27% (drying temperature), 0.15% (crack ratio), and 2.08% (relative humidity), so the relevance of the model was verified. In addition, the effect of drying temperature, airflow rate, and velocity of the airflow on the drying was examined. The experimental results showed that the crack ratio at drying temperature of $25{\sim}40^{\circ}C$ was allowable. Moreover, at below $30^{\circ}C$, variation of the crack ratio was slight, but drying time was delayed. Given these results, the drying temperature of over $30^{\circ}C$ was effective. As the airflow rate increased, required energy dramatically increased. Whereas drying rate slowly increased, so loss of drying efficiency was caused. Considering these results, the dryer needed to be designed and adjusted to lower than $30\;m^3/min{\cdot}ton$. As velocity of the airflow increased, required drying energy increased when the velocity of the airflow was over $5\;m^3$/hr, while crack ratio and drying rate showed little variation.

해안구조물 축조를 위한 해양연약지반의 강제치환 특성에 관한 원심모형실험 (Centrifuge Model Tests on Characteristics in Forced Replacement Method for Soft Ocean Ground to Build Coastal Structures)

  • 박병수
    • 한국해양공학회지
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    • 제20권5호
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    • pp.42-48
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    • 2006
  • This paper shows theresults of centrifuge model experiments to investigate the behavior of a replacement method in dredged and reclaimed ground. For this experimental work, centrifuge model tests were carried out to investigate the behavior of a replacement method in soft clay ground. Basic soil property tests were performed to find the mechanical properties of clay soil sampled from the southern coast of Korea, which was used for the ground material in the centrifuge model tests. The reconstituted clay ground of the model was prepared by applying reconsolidntion pressure in a 1 g condition with a specially built model container. Centrifuge model tests were carried out under the artificially accelerated gravitational level of 50 g. Replacement material of lead with a certain degree of angularity was used and placed until the settlement of the replacement material embankment reached a state of equilibrium. Vertical displacement of the replacement material was monitored during tests. The depth and shape of the replacement, especially the slope of the penetrated material and the water content of the clay ground were measured after finishing tests. Model tests for investigating the stability of an embankment after backfilling were also performed to simulate the behavior of a dike treated with replacement and backfilled with sandy material. As a result of the centrifuge model test, the behavior of the replacement, the mechanism of the replacement material being penetrated into clay ground, and the depth of the replacement were evaluated.

충격파 풍동의 극초음속 노즐 설계를 위한 Quasi 1D 비평형 해석 및 검증 (Quasi 1D Nonequilibrium Analysis and Validation for Hypersonic Nozzle Design of Shock Tunnel)

  • 김세환;이형진
    • 한국항공우주학회지
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    • 제46권8호
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    • pp.652-661
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    • 2018
  • 고속 고온 유동에서 나타나는 고온 기체 현상을 모사하기 위해서는 마하수뿐 아니라 절대속도도 재현할 수 있어야 한다. 이러한 유동을 초음속 유동과 구분하여 극고속 유동이라 부르며, 충격파 터널과 같은 고엔탈피 시험 장치를 통해 연구가 이루어지고 있다. 그러나 이러한 고엔탈피 시험 장비는 높은 온도와 압력 때문에 노즐에서 열화학적 비평형 현상을 경험하게 되며 기존의 이론적 방법으로 그 실험 조건을 규정하기 어렵다. 이에 본 연구에서는 알려진 비평형 노즐 코드의 단점들을 보완하고 충격파 터널의 운용 조건에서 시험부 유동 특성을 빠르게 예측하기 위하여 열화학적 비평형을 고려한 준 1차원 노즐 해석 코드를 개발하였다. 개발된 코드는 시험 결과 및 2차원 축대칭 해석 결과와 비교를 통하여 충격파 풍동 시험부 유동 조건 예측을 위한 활용성 및 한계를 살펴보았다.

고추의 건조특성(乾燥特性)과 건조모델에 관(關)한 연구(硏究) (Drying Characteristics and Drying Model of Red Pepper)

  • 조용진;고학균
    • Journal of Biosystems Engineering
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    • 제11권1호
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    • pp.52-63
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    • 1986
  • This study was performed to find out drying characteristics and develop drying model for the design of an efficient dryer or drying system of red peper. The basic model which describes drying phenomenon of red pepper was firstly established, and drying tests were conducted at 14-different drying conditions. In this test, the effects of drying air temperature and relative humidity on the rate of drying were undertaken. Finally, a new drying model based on these experimental results was developed to describe the drying characteristics of red pepper. The results from this study may be summarized as follows. 1. Drying constant of the basic model established from Lewis' experimental model and diffusion equation was theoretically deduced as a function of moisture content and inner-temperature of red pepper. 2. From the results of drying tests, drying air temperature was found to have the greatest effect on the rate of drying. However, the effect of temperature was small for the condition of high relative humidity, and for low temperature, the effect of relative humidity was found to be large even though the range of relative humidity was low. 3. Modified Henderson equation was found to be better than Chung equation as the EMC model for the estimation of the equilibrium moisture content of red Pepper. 4. Constant-rate drying period did not exist in the red pepper drying test. And falling-rate drying period was divided into three distinct phases. Drying rate was dependent on the moisture content, the inner-temperature of red pepper and the change of physical property due to drying. 5. Drying constant increased with decrease of free moisture content, but it decreased at the end of the drying period. Also, drying constant was dependent on the drying air temperature and relative humidity. 6. The new drying model developed in this study was found to be most suitable in describing the drying characteristics of red pepper. Therefore, it may be concluded that drying time could be accurately estimated by the new drying model.

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자발가압 성질을 가진 아산화질소의 2상유체 모델링을 통한 하이브리드 로켓 내탄도 해석 I (The Hybrid Rocket Internal Ballistics with Two-phase Fluid Modeling for Self-pressurizing $N_2O$ I)

  • 이정표;이선재;우경진;오지성;정식항;문희장;성홍계;김진곤
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2011년도 제37회 추계학술대회논문집
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    • pp.45-49
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    • 2011
  • 자발가압 특성이 있는 $N_2O$를 적용한 Blow-down 산화제 공급방식은 조절 시스템(Regulated system)에 비해 많은 장점을 가지고 있다. 그러나 탱크 내에 $N_2O$가 액체와 기체의 2상으로 공존하고, 유동이 배출되는 동안 탱크 안의 $N_2O$의 물성치가 계속적으로 달라지기 때문에 배출 유량을 예측하는데 어려움이 있다. 본 논문에서는 $N_2O$를 적용한 Blow-down 산화제 공급방식을 간단하게 해석 할 수 있는 방법을 연구했다. 포화상태 $N_2O$의 물성치는 NIST 데이터베이스를 이용했으며, 인젝터 모델로 nonhomogeneous nonequilibrium(NHNE) 모델을 적용하였다. 하이브리드 로켓 연소기를 이용해 cold flow test를 수행하였으며, 두 결과가 잘 일치함을 확인했다.

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국내 제조업부문의 에너지소비, 생산, 수출간의 인과관계 분석 (Analysis of Causal Relationship between Energy Consumption, Production and Export in Domestic Manufacturing Sector)

  • 김수이
    • 자원ㆍ환경경제연구
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    • 제26권1호
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    • pp.37-56
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    • 2017
  • 본 연구에서는 우리나라의 제조업을 대상으로 에너지소비, 생산, 수출의 상호 인과관계를 분석하였다. 우리나라 제조업을 9개 산업으로 나누어 1991년부터 2013년까지 패널 데이터를 구축하여 VECM 방법론과 더불어 Demitrescu and Hurlin (2012)에 의해서 개발된 패널 Granger causality test 방법을 사용하였다. 분석결과에 의하면, 생산에서 에너지소비로, 수출에서 에너지소비로의 Granger Causality가 존재하였다. 하지만 그 역으로는 Granger Causality가 성립하지 않았다. 따라서 제조업부문의 에너지절약정책은 생산이나 수출에 역효과를 발생하지 않으면서 추진될 수 있다는 Qzturk (2010)의 보존가설을 지지하고 있다. 장기적으로는 생산, 에너지소비, 수출, 노동, 자본 간에 장기 공적분관계가 존재하며, 장기균형관계에서 에너지소비가 생산의 증가에 기여하는 것으로 나타났다.

실내 방향제 사용에 의한 유해 가스상 오염물질 배출 산정 및 노출 평가 (Emission Estimation and Exposure to Hazardous Gaseous Pollutants Associated with Use of Air Fresheners Indoors)

  • 조완근;신승호;권기동;이종효
    • Environmental Analysis Health and Toxicology
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    • 제24권2호
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    • pp.137-148
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    • 2009
  • This study quantitatively investigated the emissions of indoor air pollutants associated with the utilization of air fresheners indoors, and evaluated individual exposure to five specified indoor air pollutants, which were chosen on the basis of selection criteria. An electrically-polished stainless steel chamber (50L) was employed to achieve this purpose. Test air fresheners were selected through three steps: first, on the basis of market sales; second, on the basis on a preliminary head-space study; and lastly, on the basis of emissions of toxic compounds (benzene, ethyl benzene, limonene, toluene, and xylene). The empirical mathematical model fitted well with the time-series concentrations in the environmental chamber (in most cases, determination coefficient, $R^2{\gtrsim}$0.9), thereby suggesting that the empirical model was suitable for testing emissions. The concentration equilibrium appeared 180 min after the introduction of sample air fresheners into the chamber. Both the chamber concentrations of emission rates or factors varied greatly according to air freshener type. It is noteworthy that although benzene, ethyl benzene, toluene, and xylene were emitted from all test air fresheners, their exposure levels were not significant enough to result in any significant health risk. However, certain type of air fresheners were observed to emit significant amount of limonene, which is potentially reactive with ozone to generate secondary pollutants with oxidants such as ozone, hydroxyl radicals, and nitrogen oxides. The exposure levels to limonene associated with the utilization of three air fresheners were estimated to be 13 to 175 times higher than that of other air fresheners. This information can help consumers to select low-pollutant-emitting air fresheners.

경사진 사석층의 지지력에 관한 원심모형실험 및 수치해석 (Centrifuge Model Experiments and Numerical Analysis for the Bearing Capacity of Sloped Rubble Mound)

  • 이명욱;박병수;정길수;유남재
    • 산업기술연구
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    • 제24권B호
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    • pp.95-105
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    • 2004
  • This paper is an experimental and numerical research works about the effects of the b earing capacity of sloped rubble mound on the density of rubble mound and the position of footing. Centrifuge model tests were performed to investigate the bearing capacity of rubble m ound by changing the density of rubble mound and the location of loading in forms of s trip loading to simulate the caisson. Materials of rubble mound used in the model tests were crushed rocks having similar value of uniformity coefficient to the value in field. Two different relative densities of 80% and 90% were prepared during tests. The dimens ions of centrifuge model were trapezoidal shape of model mound having the bottom wid th of mound, 30cm and height of mound, 10cm. Gravity level applied during the centrif uge test was 50G. Surcharge loading in the forms of strip loading was applied on the t op of the sloped model mound. Tests were carried out by changing the position of loadi ng. The rigid model footing was located in the center of top of the model rubble mound and the edge of model footing was at the crest of mound. Test results were analyzed by using the limit equilibrium methods proposed by Meyer hof(1957) and Bowles(1982) and the numerical approach with FLAC being available com mercially software. For the numerical estimations with FLAC, the rubble mound was si mulated with the constitutive relationship of Mohr-Coulomb elasto-plastic model.

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외부 긴장된 H형 보의 휨거동 특성 (Flexural Behavior of External Prestressed H-Beam)

  • 양동석;임상훈;박선규
    • 한국강구조학회 논문집
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    • 제14권1호
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    • pp.79-85
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    • 2002
  • 본 연구에서는 기존에 사용된 H-Beam 교량을 편향부와 외부 긴장력을 도입하여 보강효과에 의하여 지간을 증가시킬 수 있고 단면을 축소할 수 있다는 근거를 제시하였고, 유연도법을 이용하여 편향부의 효과에 의한 추가 긴장량을 산정하였다. 또한, 실험변수(긴장량, Tendon의 개수, 편향부의 유 무)에 의해서 표준실험체(기존 H-Beam)와 외부 긴장된 H-Beam 등 5개의 실험체를 제작하여 휨 실험을 실시하여 외부 긴장된 H-Beam의 역학적 거동을 연구하였다. 특히, 보강효과 및 편향부의 효과를 실험적으로 검증하였다.