• 한국환경과학회지
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• 제12권9호
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• pp.1005-1010
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• 2003

For the purpose of surveying any possibility of anchoring titanium dioxide on activated carbons to promote their activities as catalysts and/or adsorbents, two activated carbons were oxidized with ammonium peroxydisulfate and followed by anchoring titanium dioxide. The anchoring of titanium dioxide on the oxidized activated carbons were performed via the adsorption of tetrabutyltitanate, hydrolysis with deionized water, and calcination. The effect of oxidizing and anchoring treatment on the surface element composition, surface area, and pore texture were analyzed by XPS, BET and TPD. The oxidation of activated carbons with ammonium peroxydisulfate introduced carboxyl groups on the surface of activated carbons and these carboxyl groups promoted the anchoring of titanium oxide on the activated carbons. However, the treatments affected the surface area and the porosity of activated carbons.

• 한국환경과학회지
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• 제12권9호
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• pp.1017-1023
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• 2003

The high speed elimination process of suspended solid was investigated to treat the pulp waste water by using surface modified magnetite particle and magnetic power. The effects of the various aluminum salts such as Al(NO$_3$)$_3$ㆍ9$H_2O$, AlC1$_3$ㆍ6$H_2O$, $Al_2$(SO$_4$)$_3$ㆍ13∼14 on the COD, BOD and suspended solid were systematically studied. It has been found that the 2.0 wt% of Al was most effective for the modification of Fe$_3$O$_4$ powder and then best for the treatment of pulp waste water, Optimum quantity of modified magnetite in this study was 12 wt%, and aging time was found to be 12 hours. Comparing with the conventional process, the required time for SS removal was drastically decreased. BOB and COD were also effectively removed when applied to the pulp wastewater.

• Journal of Mechanical Science and Technology
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• 제20권10호
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• pp.1670-1679
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• 2006

The development of the oxidation, wear and corrosion resistant materials that could be used in severe environmental conditions is needed. The elementary technologies for surface modification include ion implantation and/or thin film coating. Furthermore, in order to develop ion implantation technique to the specimens with three-dimensional shapes, plasma-based ion implantation (PBII) techniques were investigated. As a result, it was found that the ion implantation and/or thin film coating used in this study were/was effective for improving the properties of materials, which include implantations of various kinds of ions into TiAl alloy, TiN films formed on surface of base material and coatings in high-temperature steam. The techniques proposed in this study provide useful information for all of the material systems required to use at elevated temperature. For the practical applications, several results will be presented along with laboratory test results.

• Toxicological Research
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• 제33권1호
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• pp.1-5
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• 2017

Nuclear factor E2-related factor 2 (Nrf2), a transcription factor, controls the expression of genes encoding cytoprotective proteins, including antioxidant enzymes that combat oxidative and electrophilic stress to maintain redox homeostasis. However, recent studies demonstrated that, in cancer, aberrant activation of Nrf2 by epigenetic alterations promotes high expression of cytoprotective proteins, which can decrease the efficacy of anticancer drugs used for chemotherapy. In this review, we summarize recent findings regarding the relationship between oxidative stress, Nrf2, epigenetic modification, and anticancer drug resistance, which should aid in development of new strategies to improve chemotherapeutic efficacy.

• Toxicological Research
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• 제29권2호
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• pp.81-86
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• 2013

Toxicoproteomics integrates the proteomic knowledge into toxicology by enabling protein quantification in biofluids and tissues, thus taking toxicological research to the next level. Post-translational modification (PTM) alters the three-dimensional (3D) structure of proteins by covalently binding small molecules to them and therefore represents a major protein function diversification mechanism. Because of the crucial roles PTM plays in biological systems, the identification of novel PTMs and study of the role of PTMs are gaining much attention in proteomics research. Of the 300 known PTMs, protein acylation, including lysine formylation, acetylation, propionylation, butyrylation, malonylation, succinylation, and crotonylation, regulates the crucial functions of many eukaryotic proteins involved in cellular metabolism, cell cycle, aging, growth, angiogenesis, and cancer. Here, I reviewed recent studies regarding novel types of lysine acylation, their biological functions, and their applicationsin toxicoproteomics research.

• 한국대기환경학회지
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• 제9권2호
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• pp.132-139
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• 1993

TCM has been used for many environmental impact assessments and many case studies in Korea. TCM was applied to urbvan areas and rolling terrains. But original TCM was developed for rural area, and this model could not reflect the characteristcs of these study sites. This paper analyzed the characteristics of TCM, and modified the algorithm of area source, and modified the vertical wind speed profile exponents and diffusion parameter to make it applicable in urban area. In the process of modification, an important error in area source calculation of original TCM program was found. So that was corrected as follows. $$ Before modification $QC = 0.79788456^*(0.5^*GRID)^**BA/(U(IA, IRUN)^*AA^*BA TCM09310$ After modification $QC = 0.79788456^*(500^*GRID)^**BA/(U(IA, IRUN)^*AA*BA) modified$ $$ Then original TCM and modified TCM-urban mode were compared, and it was found that predicted mean value by original TCM was 7 times higher than observed mean value. But mean value by modified TCM-urban mode was very similar to observed value.

• Bulletin of the Korean Chemical Society
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• 제28권1호
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• pp.118-120
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• 2007

• Structural Engineering and Mechanics
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• 제33권3호
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• pp.261-284
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• 2009

The seismic behavior of a framed structure with chevron-type buckling restrained braces was investigated and their behavior factors, such as overstrength, ductility, and response modification factors, were evaluated. Two types of structures, building frame systems and dual systems, with 4, 8, 12, and 16 stories were designed per the IBC 2003, the AISC LRFD and the AISC Seismic Provisions. Nonlinear static pushover analyses using two different loading patterns and incremental dynamic analysis using 20 earthquake records were carried out to compute behavior factors. Time history analyses were also conducted with another 20 earthquakes to obtain dynamic responses. According to the analysis results, the response modification factors turned out to be larger than what is proposed in the provision in low-rise structures, and a little smaller than the code-values in the medium-rise structures. The dual systems, even though designed with smaller seismic load, showed superior static and dynamic performances.

• The Plant Pathology Journal
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• 제37권6호
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• pp.505-511
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• 2021

Interaction of a pathogen with its host plant requires both flexibility and rapid shift in gene expression programs in response to environmental cues associated with host cells. Recently, a growing volume of data on the diversity and ubiquity of internal RNA modifications has led to the realization that such modifications are highly dynamic and yet evolutionarily conserved system. This hints at these RNA modifications being an additional regulatory layer for genetic information, culminating in epitranscriptome concept. In plant pathogenic fungi, however, the presence and the biological roles of RNA modifications are largely unknown. Here we delineate types of RNA modifications, and provide examples demonstrating roles of such modifications in biology of filamentous fungi including fungal pathogens. We also discuss the possibility that RNA modification systems in fungal pathogens could be a prospective target for new agrochemicals.

• 한국융합학회논문지
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• 제13권2호
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• pp.39-46
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• 2022

본 연구의 목적은 보조공학 기술을 적용한 가정환경 수정과 낙상 안전 체크리스트를 이용한 과제기반 중재를 함께 적용하는 융복합 접근법이 뇌졸중 환자의 낙상 효능감과 활동 수준에 미치는 효과를 확인하는 것이다. 뇌졸중 환자 41명 대상자(실험군 21명, 대조군 20명)는 실험군과 대조군으로 나누어졌다. 실험군에는 환경수정과 낙상 안전 체크리스트를 활용한 과제기반 중재를 4주간 적용하였다. 대조군에는 가정환경 수정만 실시하였다. 중재 전과 후에 한국형 활동분류카드(Korean Activity Card Sort, KACS), 한국형 낙상효능감 측정도구(Falls Efficacy Scale-Korean version, FES-K)를 이용하여 평가하였다. 실험군과 대조군의 낙상효능감과 활동수준의 변화량은 유의한 차이가 없었다. 실험군과 대조군은 모두 중재 이후에 낙상효능감과 활동 수준이 유의하게 향상되었다. 이러한 연구의 결과를 임상 현장에 적용하여 뇌졸중 환자가 지역사회에서 안전하게 생활하고 적극적으로 참여하는 삶을 유지할 수 있도록 지원할 수 있을 것이다.