• Journal of Integrative Natural Science
• /
• v.3 no.3
• /
• pp.162-167
• /
• 2010

A pseudoreceptor combines structure-based and ligand-based techniques to represent a unifying concept for both receptor mapping and ligand matching. In this molecular modeling approach, there are opportunities to construct the pseudoreceptor models using a set of small molecules. To build a reliable pseudoreceptor model, we need a set of ligand molecules with known affinity (biological activity) to generate 3D bioactive conformation for each of these ligand molecules. Several software packages are available to generate a pseudoreceptor model and this can provide an entry point for structure based drug discovery in cases where receptor structure information is not available. In this review, we presented the concept of pseudoreceptor, as well as discussed about various software packages available to generate a pseudoreceptor model.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.17 no.2
• /
• pp.189-195
• /
• 2008

The sequence of hydroxypyruvate isomerase gene was obtained in NCBI. In this study, the hydroxypyruvate isomerase gene of Bombyx.mori was identified and annotated with bioinformatics tools. The result was confirmed by RT-PCR, prokaryotic expression, mass spectrographic analysis and sub-cellular localization. The hydroxypyruvate isomerase cDNA comtains a 783bp ORF, and has 4 exons. The deduced protein has 260 amino acid residues with the predicted molecular weight of 29169.30 Da, isoelectric point of 6.10, and contains conserved PRK09997 and Hfi domains. The hydroxypyruvate isomerases of Nasonia vitripennis and Bombyx mori have a high homology. Through RTPCR analysis, we found that this transcript was present in testis, ovary, blood-lymph, fat body, midgut, silk gland and tuba Malpighii. This protein was located in cytoplasm through immunohistochemistry. We submitted the cloned gene under the accession number EU344910. The enzyme has been classified under accession number EC 5.3.1.22.

• Journal of applied mathematics & informatics
• /
• v.15 no.1_2
• /
• pp.265-275
• /
• 2004

In this paper, multi-objective models for designing 3D trajectory of horizontal wells are developed in a fuzzy environment. Here, the objectives of minimizing the length of the trajectory and the error of entry target point are fuzzy in nature. Some parameters, such as initial value, end value, lower bound and upper bound of the curvature radius, tool-face angle and the arc length of each curve section, are also assumed to be vague and imprecise. The impreciseness in the above objectives have been expressed by fuzzy linear membership functions and that in the above parameters by triangular fuzzy numbers. Models have been solved by the fuzzy non-linear programming method based on Zimmermann [1] and Lee and Li [2]. Models are applied to practical design of the horizontal wells. Numerical results illustrate the accuracy and efficiency of the fuzzy models.

• Journal of the Korean Society for Precision Engineering
• /
• v.20 no.10
• /
• pp.208-217
• /
• 2003

In order to construct the extrusion die surface of T -shaped sections, an automatic surface construction method based on NURBS surface and area mapping method is proposed in the present work. In the present study, a center point for area mapping is determined by introducing the mapping concept based on constant area proportionality between original billet and final product. The characteristic points of inlet profile are determined using the traditional area mapping method and the root finding numerical method. The inlet and outlet profiles are precisely described with NURBS curves using the characteristic points of entry and exit sections. For the construction of NURBS surface, an interpolation method for the pre-determined two section curves has been developed to be used in the generation of interior control points and weights. To show the validity of the proposed method, automatic die surface generation is carried out for the T-shaped section and T-shaped section with rounded corners.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 1999.08a
• /
• pp.47-56
• /
• 1999

New rolling speed prediction model has been developed for the precise presetting rolling speed of each finishing mill stand in the tandem hot strip mill. Those factors such as neutral point, work roll diameter, rolling torque, friction coefficient, bite angle and the thickness at each side of entry and deliver of the rolls were taken into account. To consider width effect on forward slip, calibration factors obtained from rolling torque has been added to new prediction model and refining method has also been developed to reduce the speed unbalance between adjacent stands. The application of the new model showed a good agreement in rolling speeds between the predictions and the actual measurements, and the standard deviation of prediction error has also been significantly reduced.

• Asian Journal for Public Opinion Research
• /
• v.5 no.1
• /
• pp.15-40
• /
• 2017

This paper addresses the zero-sum of soft power against the backdrop of the rise of China and the relative "decline" of America. It attempts to find out that whether the "decline" of America's soft power is caused by the rise of China's soft power, and whether China's rise could guarantee with certainty the growth of soft power. In light of the particularity of South Korea, that is, its economy relies on China and its security relies on the US, this paper chooses South Korea as the entry point for the study. Based on the Pew data from a South Korean opinion poll, this paper conducts bivariate correlation and binary logistic regression respectively, to explore the existence of zero-sum "competitions" between China's and America's soft power.

• 제어로봇시스템학회:학술대회논문집
• /
• 2000.10a
• /
• pp.40-40
• /
• 2000

Generally a RF AGC controls the roll gap using the variation of rolling force caused by the roll eccentricity and the entry thickness of material, but these can not be classified. The Feed- forward AGC method, which controls the next stand roll 9ap by estimation the skid mark of the previous stand output thickness is needed to supplement the shortage of RF AGC. In this paper, an improved filtering method of skid mark which take account of the kinds of materials, the final objective thickness and the roll speed is proposed, In addition, an improved estimation method of control point using the speedometer and looper angle is suggested, Via simulation, the performance improvement of the suggested FF AGC method is verified.

• Transactions of Materials Processing
• /
• v.8 no.6
• /
• pp.583-590
• /
• 1999

New forward slip model has been developed for the precise prediction of rolling speed in the hot strip finishing mill. Besides those influential factors such as neutral point, work roll diameter, friction coefficient, bite angle and the thickness at each side of entry and delivery of the rolls, roll torque was specifically taken into account in this study. To consider the effect of width change on forward slip, calibration factors obtained from rolling torque has been added to new prediction model and refining method has also been developed to reduce the speed unbalance between adjacent stands. The application of the new model showed a good agreement in rolling speeds between the predictions and the actual measurements, and the standard deviation of prediction error has also been significantly reduced.

• Transactions of Materials Processing
• /
• v.12 no.4
• /
• pp.348-357
• /
• 2003

In order to construct the extrusion die surface of arbitrarily shaped sections, an automatic surface construction method based on NURBS surface and area mapping method is proposed in the present work. A center point fur area mapping is determined by introducing the mapping concept based on constant area proportionality between original billet and final product. The characteristic points of inlet profile are determined using the traditional area mapping method and the root finding numerical method. The inlet and outlet profiles are precisely described with NURBS curves using the characteristic points of entry and exit sections. For the construction of NURBS surface, an interpolation method for the pre-determined two section curves has been developed to be used in the generation of interior control points and weights. To show the validity of the proposed method, automatic die surface generation is carried out for the several kinds of shaped sections.

• Journal of Korean Society for Atmospheric Environment
• /
• v.11 no.4
• /
• pp.373-375
• /
• 1995

In order to turn the Bag Filter to the Purse Filter, the past system that the adverse reason is removed, the input of synthetic materiality of dust and air is placed down, and the output is placed up has been improved so that any adverse effect shall not be raised. The form of filteration mechanism is changed from a cylinder from, and the dust and air is mixed to make the entry velocity and one person can velocity of the mixed materiality become lower by the use of infinity, and the reception of filteration mechanism has been made reasonably. The dust separated from the filteration mechanism is desceded down, snd the mixde materiality is ascended up. So, a cross point is formed, and a collision and a friction is occurred from its process, and at its result, dust is scattered to stick to a filter cloth, therefore, the loss of pressure shall ont be appeared by cause of the increase of dust-loading.