• 제목/요약/키워드: enhancing effect

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Acetaminophen과 Acetaldehyde로 유발된 간세포독성에 대한 애엽 물추출물의 영향 (Effect of Water Extract from Artemisiae Argi Folium on Hepatotoxicity Caused by Acetaminophen and Acetaldehyde)

  • 박완수
    • 동의생리병리학회지
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    • 제22권5호
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    • pp.1210-1214
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    • 2008
  • The purpose of this study is to investigate the effect of water extract from Artemisiae Argi Folium (WAAF) on hepatotoxicity caused by acetaminophen (AAP) and acetaldehyde which are regarded as hepatotoxin. Artemisiae Argi Folium was known to have the antibacterial, immune-enhancing, and anticoagulative properties. In Korean Medicine, Artemisiae Argi Folium is supposed to be related with 'liver meridian' according to traditional medical theory. AAP and acetaldehyde reduce the intracellular production of hydrogen peroxide ($H_2O_2$) and nitric oxide (NO) production of human hepatocyte HepG2. The intracellular production of hydrogen peroxide ($H_2O_2$) was measured by dihydrorhodamine 123 (DHR) assay. NO production was measured with Griess test. WAAF increased the production of $H_2O_2$ and NO reduced by AAP and acetaldehyde in HepG2 cells. Therefore, It could be suggested that WAAF has the hepatoprotective activity against AAP and acetaldehyde.

STUDIES ON ENHANCING CHEMOPREVENTIVE EFFECT OF CHUNGKOOKJANGS 1. ENHANCED ANTIMUTAGENIC ACTIVITY OF CHUNGKOOKJANGS PREPARED WITH THE DIFFERENT VARIETY OF SOYBEAN AND STARTER

  • Park, Kun-Young;Kwon, Eun-Young;Jung, Keun-Ok
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.99-99
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    • 2001
  • Antimutagenic effect of chungkookjangs prepared with the different variety of soybean and starter were studied against aflatoxin B$_1$ (AFB1) using Ames test and Ν-methyl-Ν'-nitro-Ν- nitrosoguanidine (MNNG) using SOS chromotest. Chungkookjang samples exerted the different antimutagenicity according to the prepared variety of soybeans in the Ames test using Salmonella typhimurium TA100. The chungkookjang manufactured with var.(omitted)

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Ownership Concentration, Board Education Diversity, and Environmental Accounting Disclosure in Kenyan Listed Firms. Moderation Approach

  • TARUS, John Kipngetich
    • 웰빙융합연구
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    • 제3권1호
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    • pp.1-10
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    • 2020
  • The purpose of this study was to examine the moderating effect of board education diversity on the relationship between ownership concentration and environmental accounting disclosure. The study was driven by stakeholder's theory. The longitudinal research design was adopted in the study. The study targeted 27 listed firms from 2008 to 2017. Panel regression analysis results indicated ownership concentration (β = -.131, ρ<.05) had a negative and significant effect on environmental disclosure in Kenyan firms. However, Board education diversity positively moderated the relationship between ownership concentration (β=.138, ρ<.05) and environmental accounting disclosure. Thus, board education diversity is an enhancing moderator in the relationship between ownership concentration and environmental accounting disclosure. The findings validate stakeholder theory's proposition. The study recommends that firms listed in the NSE ought to diffuse ownership concentration, and their boards should be well educated and experienced to enhance environmental accounting disclosure.

Helium/Oxygen Atmospheric Pressure Plasma Treatment on Poly(ethylene terephthalate) and Poly(trimethylene terephthalate) Knitted Fabrics: Comparison of Low-stress Mechanical/Surface Chemical Properties

  • Hwang Yoon Joong;McCord Marian G.;Kang Bok Choon
    • Fibers and Polymers
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    • 제6권2호
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    • pp.113-120
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    • 2005
  • Helium-oxygen plasma treatments were conducted to modify poly(trimethylene terephthalate) (PIT) and poly(ethylene terephthalate) (PET) warp knitted fabrics under atmospheric pressure. Lubricant and contamination removals by plasma etching effect were examined by weight loss $(\%)$ measurements and scanning electron microscopy (SEM) analysis. Surface oxidation by plasma treatments was revealed by x-ray photoelectron spectroscopy (XPS) analyses, resulting in formation of hydrophilic groups and moisture regain $(\%)$ enhancement. Low-stress mechanical properties (evaluated by Kawabata evaluation system) and bulk properties (air permeability and bust strength) were enhanced by plasma treatment. Increasing interfiber and interyarn frictions might play important roles in enhancing surface property changes by plasma etching effect, and then changing low-stress mechanical properties and bulk properties for both fabrics.

The Effect of Ethical Leadership on the Organizational Effectiveness

  • Lee, Seung-Kyu
    • 한국컴퓨터정보학회논문지
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    • 제20권12호
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    • pp.163-168
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    • 2015
  • Empirical studies of superior's ethical leadership on organizational effectiveness of organization member have been done in various fields. However, it is difficult to find the previous research on civil servant in public sector. Therefore, the purpose of this study is to analyse causal relationship of ethical leadership and organizational effectiveness and to suggest theoretical and political implication for enhancing the level of civil servant's organizational citizenship behavior. As the result of analysing the causal relationship of superior's ethical leadership and organizational citizenship behavior, the factor of organizational effectiveness as the public attitude, this study shows that normative behavior, communication, reinforcement, and right decision-making have significant effect on organizational citizenship behavior. Based on these results, this study suggested theoretical and political implication and the limitations of study.

The Effect of Surface Area of Silicas on Their Reinforcing Performance to Styrene-butadiene Rubber Compounds

  • Ryu, Changseok;Kim, Sun Jung;Kim, Do Il;Kaang, Shinyoung;Seo, Gon
    • Elastomers and Composites
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    • 제51권2호
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    • pp.128-137
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    • 2016
  • The effect of the surface area of silicas on their reinforcing performance to styrene-butadiene rubber (SBR) compounds was systematically investigated. The feasibility of the Brunauer-Emmett-Teller surface area ($S_{BET}$) as a parameter representing the characteristics of the silicas was discussed compared to the mesopore volume, c value, oil absorption, and uptake of silane. The increase in $S_{BET}$ of silicas caused a considerable increase in Mooney viscosity, minimum torque, and hysteresis loss of the silica-filled SBR compounds, while significantly enhancing their abrasion property. These changes were explained by the attrition between the hydrophilic silica surface and the hydrophobic rubber chains. As expected, the change in $S_{BET}$ did not induce any remarkable changes in the cure, processing, tensile, and dynamic properties of the silica-filled SBR compounds because the crosslinking density of the rubber chains mainly determined these properties.

Effect of Catalyst Type and NCO Index on the Synthesis and Thermal Properties of Poly(urethane-isocyanurate) Foams

  • Shin, Hye-Kyeong;Lee, Sang-Ho
    • Elastomers and Composites
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    • 제53권2호
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    • pp.86-94
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    • 2018
  • The effect of the NCO index and catalyst type on the thermal stability of poly(urethane-isocyanurate) (PUIR) foams was investigated to identify a method for enhancing the flame resistance of PUIR. PUIR foams were prepared using 4,4-diphenylmethane diisocyanate (MDI) and [(diethylene glycol)adipate]diol, which were synthesized by esterification of adipic acid and diethylene glycol. Dabco K-15, Dabco TMR-30, and Toyocat RX-5 were used as the catalysts for trimerization and gelation. The amount of urea and isocyanurate groups in PUIR was semi-quantitatively determined by normalizing their absorbance with the phenyl absorbance measured by FT-IR. The normalization data showed that Dabco TMR-30 effectively generated isocyanurate groups in PUIR. As a result, Dabco TMR-30 effectively raised the decomposition temperature and increased the 800 K and 900 K residues of the PUIR foam synthesized with an NCO index of 200.

Development of Polymeric Layer for Enhancing The Adhesion of Nano-devices Fabricated by The Nanotransfer Molding Method

  • 이기석;성명모
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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    • pp.634-634
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    • 2013
  • Transfer molding methods have a problem that weak adhesion between nanostructures and substrates. It is important to make various nano scale applications, also the stability of nanostructure on substrate is related with device performance. We studied an effect of poly 4-vinylphenol (PVP) as the polymeric adhesion layer between organic nanowires and a Si substrate when the nanowires are transferred by liquid-bridge-mediated nanotransfer molding method (LB-nTM). Their structural stability was examined by optical microscopy, scanning electron microscopy as multiple transfer molding and washing process. Field-effect transistors were fabricated with organic semiconductor nanowires on a polymeric adhesion layer and their electrical properties showed no significant difference as the one without the adhesion layer. As a result, adhesion layer can be used in the washing process and making multi-layer nano-scale patterns.

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Transdermal Delivery of Piroxicam Using Microemulsions

  • Park Eun-Seak;Cui Yu;Yun Bum-Jin;Ko In-Ja;Chi Sang-Cheol
    • Archives of Pharmacal Research
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    • 제28권2호
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    • pp.243-248
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    • 2005
  • To improve the skin permeability of piroxicam, a new oil-in-water microemulsion containing $0.5\%$ piroxicam was developed. Among various oils investigated for their suitability as an oil phase for the microemulsion system, oleic acid showed both excellent solubility and skin permeation enhancing effect for piroxicam. Microemulsion existence ranges were identified through the construction of the pseudo-ternary phase diagram. The effect of the content of oleic acid and the ratio of the surfactant/cosurfactant on skin permeation of piroxicam were evaluated with excised rat skins. The optimum formulation with the highest skin permeation rate ($47.14\;{\mu}g/cm^2/h$) consisted of $0.5\%$ piroxicam, $10\%$ oleic acid, $60\%$ Labrasol/ethanol (1:5) and water.

PELE의 경사진 충격에 따른 파괴 메커니즘에 대한 연구 (A Study of Failure Mechanism for Inclined Impact of PELE)

  • 조종현;이영신
    • 한국군사과학기술학회지
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    • 제15권5호
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    • pp.712-719
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    • 2012
  • Penetrator with enhanced lateral effect(PELE) is a newconcept projectile, without dynamite and fuze. It consists of high-density jacket, closed at its rear end and filled with a low-density filling material. To study the explosion characteristics of PELE, by AUTODYN-3D code, the calculation models of projectile body and bullet target are established and the process of penetrating aluminum-2024 alloy target of PELE is simulated, and the scattering characteristics after penetrating aluminum-2024 alloy target of PELE are studied by different initial velocity. The explicit finite element analysis of PELE fragmentation was implemented with stochastic failure criterion in AUTODYN-3D code. As expansion of filling, the fragments were obtained velocities and dispersed laterally and further more enhancing the damage area largely. The number and shape of the PELE fragments were different depend on impact velocity and incidence angle of filling which fragment generated during penetration and lateral dispersion process.