• 제목/요약/키워드: effect size(ES)

검색결과 56건 처리시간 0.024초

세로토닌 재흡수 억제제에 대한 아리피프라졸 및 부프로피온 부가요법의 우울증 세부증상에 대한 효과 비교 : 다기관, 개방표지, 무작위 연구 (Comparative Effectiveness of Adjunctive Aripiprazole versus Bupropion Uses to Selective Serotonin Reuptake Inhibitor on the Specific Symptom of Depression : A post-hoc, Multi-Center, Open-Label, Randomized Study)

  • 이가원;이광헌;박영우;이종훈;구본훈;이승재;성형모;천은진
    • 대한불안의학회지
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    • 제13권2호
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    • pp.66-73
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    • 2017
  • 우울증은 높은 유병률을 가지며 심각하고 만성화 될 수 있는 질병이다. 환자가 증상 없이 기능적 회복이 되어 일상을 영위하기 위해 임상가는 단독요법 이상의 치료 전략이 필요하다. 본 연구에서 SSRI와 aripiprazole 또는 bupropion 부가 요법은 우울증의 증상 호전을 보였다. SSRI와 aripiprazole 부가 요법은 우울증의 전반적 점수의 호전뿐 아니라 세부척도의 핵심 증상에서 bupropion 병합 요법에 비해 더 의미 있는 변화를 보였다. 또한 두 약제 모두 핵심 우울증상이라 할 수 있는 개별증상(우울한 기분, 일과 활동, 정신적 불안)에서 가장 큰 변화를 보였다

정보활용교육의 효과에 대한 메타분석 (Meta-analysis on the Effect of Information Literacy Instruction)

  • 김승희;홍세희
    • 한국비블리아학회지
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    • 제27권1호
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    • pp.59-85
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    • 2016
  • 본 연구는 정보활용교육의 효과를 메타분석 방법으로 통합하여 제시하고자 45편의 연구에서 총 69개의 효과크기를 수집하여 분석하였다. 무선효과 모형을 적용한 연구결과는 다음과 같다. 첫째, 정보활용교육의 전체 효과크기 평균은 0.72(Hedges'g)로 Cohen의 해석기준에 의하면 중간 이상 크기를 보였다. 둘째, 정보활용 교육을 단독형태와 교과연계형태로 구분하여 분석한 결과, 두 가지 유형 모두 중간 이상 크기의 효과가 있으며 유형에 따른 차이는 없었다. 셋째, 정보활용교육의 효과크기는 측정변인에 따라 차이가 있는 것으로 나타났다. 측정변인별 효과크기는 정보활용능력, 인지적 특성, 문제해결능력, 학업성취, 자기주도적 학습능력, 정의적 특성 순으로 나타났다. 넷째, 대상학년, 연구설계 유형, 측정도구 형태가 효과크기의 차이를 설명하는 조절변수로 나타났다. 메타분석결과를 종합하면 정보활용교육은 교육유형, 연구특성 등에 큰 영향을 받지 않고 안정적이며 중간크기 이상의 효과를 가지고 있다고 볼 수 있다.

나노입자 첨가 유리섬유강화 복합재료의 전자기파 차폐특성 (Electromagnetic-wave Shielding by Nano Particles-contained Glass Fiber Reinforced Composite Materials)

  • 정우균;안성훈;원명식
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2004년도 추계학술대회 논문집
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    • pp.1331-1334
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    • 2004
  • The research on electromagnetic shielding has been advanced for military applications as well as for commercial products. Utilizing the reflective properties and absorptive properties of shielding material, the replied signal measured at the rear surface or at the signal source can be minimized. The shielding effect was obtained from materials having special absorptive properties or from structural characteristics such as stacking sequence. Recently researchers studied the electromagnetic properties of nano size particles. In this research {glass fiber}/{epoxy}/{nano particle} composites(GFR-Nano composites), was fabricated using various nano particles, and their properties in electromagnetic shielding were compared. For the visual observation of the nano composite materials, SEM(Scanning Electron Microscope) and TEM(Transmission Electron Microscope) were used. For the measurement of electromagnetic shielding, HP8719ES S-parameter Vector Network Analyser System was used on the frequency range of 8 GHz~12GHz. Among the nano particles, carbon black and Multi-Walled Carbon Nano-Tube (MWCNT) revealed outstanding electromagnetic shielding. Although silver nano particles (flake and powder) were expected to have effective electromagnetic shielding due to their excellent electric conductivities, test showed little shielding effect.

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유리섬유강화 나노 복합재료의 전자기파 차폐효과 비교 (Comparison of Electromagnetic-wave Shielding Effect in Glass Fiber Reinforced Nano Composites)

  • 정우균;원명식;안성훈
    • 한국정밀공학회지
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    • 제22권10호
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    • pp.121-128
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    • 2005
  • The research on electromagnetic shielding has been advanced for military applications as well as for commercial products. Utilizing the reflective properties and absorptive properties of shielding material, the replied signal measured at the rear surface or at the signal source can be minimized. The shielding effect was obtained from materials having special absorptive properties and structural characteristics such as stacking sequence. Recently researchers studied the electromagnetic properties of nano size particles. In this research {glass fiber}/{epoxy}/{nano particle} composites(GFR-Nano composites) was fabricated using various nano particles, and their properties in electromagnetic shielding were compared. For the visual observation of the nano composite materials, SEM(Scanning Electron Microscope) and TEM(Transmission Electron Microscope) were used. For the measurement of electromagnetic shielding, HP8719ES S-parameter Vector Network Analyser System was used on the frequency range of 8 GHz${\~}$12GHz. Among the nano particles, carbon black and Multi-Walled Carbon Nano-Tube (MWCNT) revealed outstanding electromagnetic shielding. Although silver nano particles (flake and powder) were expected to have effective electromagnetic shielding due to their excellent electric conductivities, test results showed little shielding characteristics.

향기요법이 스트레스에 미치는 효과에 대한 메타 분석 (Meta-Analysis about Effect of Aromatherapy on Stress)

  • 김경덕;서순림
    • Journal of Hospice and Palliative Care
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    • 제11권4호
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    • pp.188-195
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    • 2008
  • 목적: 본 연구의 목적은 향기요법이 스트레스에 미치는 효과에 대하여 메타분석 방법을 이용하여 연구결과의 정도를 종합, 분석하기 위함이다. 방법: 2000년 1월부터 2008년 2월까지 이루어진 연구를 대상으로 하여 국내 학위논문과 주요 학술지를 중심으로 추출하였으며, 향기요법이 스트레스에 미치는 효과를 연구한 45편의 논문 중 분석대상 기준에 적합한 논문 21편을 대상으로 하였으며, 자료분석은 통계프로그램인 SAS 9.1/PC을 이용하여 분석하였다. 결과: 최종 선정된 21편의 연구물로부터 58개의 효과 크기가 산출되었으며, 58개의 효과크기를 바탕으로 전체 효과, 종속변수의 지표별 효과, 연구대상 및 중재 방법에 대한 효과, 중재시간에 따른 효과를 산출하였다. 향기요법이 스트레스에 미치는 전체 효과크기는 .593으로 보통 효과크기로 나타났다. 스트레스의 지표별 효과 크기는 생리적 지표에서 보다 심리적 지표에서 훨씬 큰효과를 보였으며, 심리적 스트레스에서는 주관적 스트레스에 효과가 가장 컸고($\bar{d}$=.983), 생리적 스트레스에서는 코티졸($\bar{d}$=.648)과 맥박($\bar{d}$=.515)에서는 중간정도의 효과크기가 나타났으나, 수축기 혈압($\bar{d}$=.490)과 이완기혈압($\bar{d}$=.401), 에피네피린($\bar{d}$=.334)에서는 중재효과가 작은 것으로 나타났다. 대상자별 효과에서는 노인집단에서 .706으로 가장 큰 효과를 나타내었고, 암환자($\bar{d}$=.337)에게 가장 작은 효과로 나타나 집단간 유의한 차를 보였다(F=2.271, P=.043). 중재방법에 대해서는 향기요법과 마사지요법을 병행한 경우($\bar{d}$=.590) 가장 큰 효과로 나타났으나 중재시간별 효과크기의 차는 없었다 (F=.495, P=.687). 중재시간에 대해서는 $20{\sim}30#분의 중재를 한 경우 .730으로 가장 높게 나타났으나, 역시 통계적 유의한 차는 없었고, 중재 회기 수와 효과크기와의 상관관계는 r=.349로 나타나 통계적으로 유의한 차를 보였다(P=.007). 결론: 본 연구 결과 향기요법은 대상자의 스트레스를 감소시키는데 효과가 있는 것으로 나타났으므로 향기요법을 이용한 간호중재 프로토콜의 개발과 그 실제 적용이 요구된다할 수 있겠으며, 프로토콜 개발 시 대상자의 특성과 중재 시간이 고려되어야 하겠다.

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Breast Density and Risk of Breast Cancer in Asian Women: A Meta-analysis of Observational Studies

  • Bae, Jong-Myon;Kim, Eun Hee
    • Journal of Preventive Medicine and Public Health
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    • 제49권6호
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    • pp.367-375
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    • 2016
  • Objectives: The established theory that breast density is an independent predictor of breast cancer risk is based on studies targeting white women in the West. More Asian women than Western women have dense breasts, but the incidence of breast cancer is lower among Asian women. This meta-analysis investigated the association between breast density in mammography and breast cancer risk in Asian women. Methods: PubMed and Scopus were searched, and the final date of publication was set as December 31, 2015. The effect size in each article was calculated using the interval-collapse method. Summary effect sizes (sESs) and 95% confidence intervals (CIs) were calculated by conducting a meta-analysis applying a random effect model. To investigate the dose-response relationship, random effect dose-response meta-regression (RE-DRMR) was conducted. Results: Six analytical epidemiology studies in total were selected, including one cohort study and five case-control studies. A total of 17 datasets were constructed by type of breast density index and menopausal status. In analyzing the subgroups of premenopausal vs. postmenopausal women, the percent density (PD) index was confirmed to be associated with a significantly elevated risk for breast cancer (sES, 2.21; 95% CI, 1.52 to 3.21; $I^2=50.0%$). The RE-DRMR results showed that the risk of breast cancer increased 1.73 times for each 25% increase in PD in postmenopausal women (95% CI, 1.20 to 2.47). Conclusions: In Asian women, breast cancer risk increased with breast density measured using the PD index, regardless of menopausal status. We propose the further development of a breast cancer risk prediction model based on the application of PD in Asian women.

수학학습부진아 지도방법에 따른 학업성취도 향상에 대한 메타연구 (Meta analysis on the improvement of academic performance by the teaching method for underachievers of learning mathematics)

  • 김홍겸
    • 한국수학교육학회지시리즈A:수학교육
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    • 제59권1호
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    • pp.31-45
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    • 2020
  • 시대적 흐름과 정부의 정책 시행 노력에도 불구하고 수학학습에 어려움을 호소하는 학생들이 많이 늘어나고 있다. 이를 반영하여 수학교육에서 수학학습부진아와 관련된 연구가 많이 시행되었다. 하지만 이러한 연구들의 대부분은 수학학습부진아의 원인을 밝혀내거나 교수학적 처치를 시행하고 그 효과를 알아보는 실험연구가 대부분이었다. 따라서 본 연구에서는 학위논문 및 학술지 논문 49편을 메타분석하여 수학학습부진에 대한 교수학적 처치가 학업성취도 향상에 얼마나 큰 효과크기를 갖는지 분석하였다. 이러한 분석의 결과 수학학습부진아에게 교수학적 처치는 전반적으로 중간 정도의 효과크기를 갖는다는 것을 알게 되었다. 또한 여러 중재요인을 분석하여 어떠한 환경에서 가장 큰 효과를 거둘 수 있는지에 대한 제안점도 얻을 수 있었다.

Control the length of beam trajectory with a quadruple triplet for heavy ion accelerator

  • Wei, Shaoqing;Zhang, Zhan;Lee, Sangjin;Kim, Do Gyun;Kim, Jang Youl
    • 한국초전도ㆍ저온공학회논문지
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    • 제18권4호
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    • pp.40-43
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    • 2016
  • Beam trajectory is needed to be controlled in heavy ion accelerator system. Quadruple magnets are widely used in heavy ion accelerator for focusing the transporting particles. A quadruple triplet system which consists of three consecutive quadrupoles, Q1, Q2 and Q3, is used to control beam trajectory at a focused position. Q1 and Q3 have symmetry with respect to Q2. The beam trajectory in magnet system is affected by higher order fields existed in real fields. For quadrupoles, the representation simulation of beam trajectory was carried out to study the beam trajectory and to estimate an effect of higher order field in triplet system. SCALA program was used to simulate the beam trajectory in $Opera^{TM}$. SCALA can analyze a large number of beam trajectories at the same time by adjusting the size of finite element of the emitter. With $Opera^{TM}$ and $Matlab^{TM}$ programs, the position of focused beam spot in quadruple triplet system can be increased or decreased using evolution strategy (ES) method, therefore the length of triplet system can be controlled. Finally, the quadruple triplet system with the appropriate length and expected beam spot range was suggested in this paper.

Reliability and Validity of Patient Oriented Eczema Measure (POEM) Korean Version

  • Kim, Yoon-Ha;Han, Jong-Min;Jung, In-Chul;Kang, Weechang;Park, Yang-Chun
    • 대한한의학회지
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    • 제37권4호
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    • pp.22-29
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    • 2016
  • Objectives: We developed a Korean translation of this questionnaire by sequential forward-and-backward translation. The purpose of this study is to validate the Korean version of the POEM, the "POEM-K" by Korean patients with atopic dermatitis (AD). Methods: A single-center prospective study was conducted with 50 participants diagnosed with AD. The POEM was translated to Korean version by an expert panel. Scoring Atopic Dermatitis (SCORAD) and Short Form 36 Health Survey (SF-36) were used as external comparators. Results: Twenty men and thirty women between the ages of 18 and 63 participated in the study. The test-retest reliability of the total POEM-K was estimated using the intra-class correlation coefficient (ICC) that showed a strong agreement (ICC = 0.72). By using Pearson correlation coefficients, we compared the POEM-K to SCORAD and yielded a concurrent validity that showed a significant result. The responsiveness of the POEM-K was represented by the effect size (ES) of 1.41 and statistically significant (p = 0.004). Conclusions: The Korean version of the POEM is a reliable, valid, and responsive disease-specific questionnaire for assessing the symptoms and quality of life of Korean patients with AD.

Bending behavior of squared cutout nanobeams incorporating surface stress effects

  • Eltaher, Mohamed A;Abdelrahman, Alaa A.
    • Steel and Composite Structures
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    • 제36권2호
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    • pp.143-161
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    • 2020
  • In nanosized structures as the surface area to the bulk volume ratio increases the classical continuum mechanics approaches fails to investigate the mechanical behavior of such structures. In perforated nanobeam structures, more decrease in the bulk volume is obtained due to perforation process thus nonclassical continuum approaches should be employed for reliable investigation of the mechanical behavior these structures. This article introduces an analytical methodology to investigate the size dependent, surface energy, and perforation impacts on the nonclassical bending behavior of regularly squared cutout nanobeam structures for the first time. To do this, geometrical model for both bulk and surface characteristics is developed for regularly squared perforated nanobeams. Based on the proposed geometrical model, the nonclassical Gurtin-Murdoch surface elasticity model is adopted and modified to incorporate the surface energy effects in perforated nanobeams. To investigate the effect of shear deformation associated with cutout process, both Euler-Bernoulli and Timoshenko beams theories are developed. Mathematical model for perforated nanobeam structure including surface energy effects are derived in comprehensive procedure and nonclassical boundary conditions are presented. Closed forms for the nonclassical bending and rotational displacements are derived for both theories considering all classical and nonclassical kinematics and kinetics boundary conditions. Additionally, both uniformly distributed and concentrated loads are considered. The developed methodology is verified and compared with the available results and an excellent agreement is noticed. Both classical and nonclassical bending profiles for both thin and thick perforated nanobeams are investigated. Numerical results are obtained to illustrate effects of beam filling ratio, the number of hole rows through the cross section, surface material characteristics, beam slenderness ratio as well as the boundary and loading conditions on the non-classical bending behavior of perforated nanobeams in the presence of surface effects. It is found that, the surface residual stress has more significant effect on the bending deflection compared with the corresponding effect of the surface elasticity, Es. The obtained results are supportive for the design, analysis and manufacturing of perforated nanobeams.