• Advances in pediatric surgery
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• 제6권1호
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• pp.45-49
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• 2000

Henoch-Sch$\ddot{o}$nlein purpura is a systemic vasculitis of unknown etiology that is probably related to an autoimmune phenomenon. Henoch-Sch$\ddot{o}$nlein purpura is characterized by a purpuric rash, arthralgia, nephritis, and gastrointestinal manifestations. We reviewed 169 children hospitalized with a diagnosis of Henoch-Sch$\ddot{o}$nlein purpura between 1989 and 1998. One-hundred thirty-nine (82.2 %) had gastrointestinal findings including abdominal pain, nausea, vomiting and gastrointestinal bleeding. Surgical consultations were obtained for ten children, and laparotomy was performed in five. Three children suspected of having appendicitis underwent appendectomy. None had appendicitis. One child thought to have been intestinal strangulation was found to have hemorrhagic edema of the proximal jejunum and of the distal ileum. Another child underwent resection for an hemorrhagic infarct of the distal ileum. A high index of suspicion of this disease entity in the differential diagnosis of abdominal pain in children can avoid unnecessary laparotomy in most cases. However, life-threatening gastrointestinal complications may occur in low percentage of cases. Prompt recognition and adequate radiologic evaluation of the abdominal manifestation of this entity is necessary for early surgical intervention.

• 가정과삶의질연구
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• 제21권2호
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• pp.145-154
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• 2003

As the life-expectancy is ever-increasing, and the proportion of the elderly population is growing steadily in every society of the world, it is ever more important to establish what factors allow certain elderly people to age successfully and remain relatively independent while others grow old less successfully and require extensive intervention. However, there is no consensus yet as to what successful aging means. Researchers have defined successful aging in a variety of ways. This study attempted to define the concept of successful aging and to clarify some dimensions of it through literature review. Previous approaches of studying successful aging and related themes were examined. Early perspectives including activity, disengagement, and continuity theories, Selective Optimization with Compensation (SOC) model by Baltes and Baltes, three different conceptions of successful aging, that is, psychological well-being, physical health, and wisdom, and MacArthur research on successful aging have been reviewed for this study. The definition derived from the review is: Keeping up continuous developmental processes to achieve wisdom or ego-integrity, without suffering any major disabilities in either physical or mental functioning, while maintaining psychological well-being and employing SOC strategies, and participating in positive relationships with significant others. The dimensions of successful aging are 1) personal resources, including physical health, cognitive competences, self esteem, and social support 2) adaptation process of SOC, and 3) psychological aspects, including psychological well-being and wisdom.

• BMB Reports
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• 제53권1호
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• pp.47-55
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• 2020

Alzheimer's disease (AD) is a multifactorial neurodegenerative disease and has become a major socioeconomic issue in many developed countries. Currently available therapeutic agents for AD provide only symptomatic treatments, mainly because the complete mechanism of the AD pathogenesis is still unclear. Although several different hypotheses have been proposed, mitochondrial dysfunction has gathered interest because of its profound effect on brain bioenergetics and neuronal survival in the pathophysiology of AD. Various therapeutic agents targeting the mitochondrial pathways associated with AD have been developed over the past decade. Although most of these agents are still early in the clinical development process, they are used to restore mitochondrial function, which provides an alternative therapeutic strategy that is likely to slow the progression of the disease. In this mini review, we will survey the AD-related mitochondrial pathways and their small-molecule modulators that have therapeutic potential. We will focus on recently reported examples, and also overview the current challenges and future perspectives of ongoing research.

• 여성건강간호학회지
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• 제11권2호
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• pp.163-168
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• 2005

Purpose: This study was to identify the relationship between fatigue and sleep disturbance in adult women so as to provide basic data for developing a women's health promotion program and nursing intervention. Method: A convenience sample of 184 women who visited a Well-baby clinic at P city Maternal child center during October in 2004 was obtained. Data was collected by self-administered questionnaires. Results: The Subjects' mean age was 36.87 years and 70% were employed and had more education than high school. The mean level of fatigue was 56.65, mean sleeping hours were 6.54, and time until falling asleep was 17.58 minutes. Scores of fatigue differed by subject's age, level of education, and menstruation status. In addition, sleeping hours differed by age, occupation status, and income level. There were significant low levels of correlation between fatigue and sleeping hours (r=-.16) and getting up too early (r=-.15). Conclusion: This study concludes that fatigue and sleeping patterns have a significant relationship.

• 여성건강간호학회지
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• 제10권1호
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• pp.8-14
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• 2004

Purpose: The purpose of this study was to look into back pain, pain disability, labour pain, and related areas of pain experienced by postpartum women. Method: A survey about pain including a Visual Analogue Scale (VAS), Oswestry pain disability, and pain drawing was used in a descriptive research method on 98 women 2-3 days after delivery. Result: 57.1% of those surveyed reported experiencing back pain before pregnancy. 75.5% reported experiencing back pain during pregnancy. The average starting time of back pain for pregnant women was 2.9 months into pregnancy. 48.8% reported the most severe back pain in the last trimester of pregnancy, while most women complained of left and right pubic pain and lumbar area pain during pregnancy. Statistical relations were calculated and menstrual symptoms (F=5.938, p=0.004), back pain prior to pregnancy (F=4.714, p=0.000), back pain during pregnancy (F=-3.429, p=0.001), and back pain disability prior to pregnancy (F=-1.994). Conclusion: There is a relation in postpartum women's back pain between back pain prior to pregnancy and back pain during pregnancy. Pelvic examinations early in pregnancy can determine if back pain will change for the worse or relapse. Therefore, the application of a pain relieving nursing intervention is needed.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제45권6호
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• pp.364-368
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• 2019

A Le Fort I osteotomy is a common procedure for correcting dental and facial deformities in orthognathic surgery. In rare cases, a delayed hemorrhage can occur as early as several hours or up to 12 weeks, postoperatively. The most frequently involved blood vessels in a delayed hemorrhage are the descending palatine artery, the internal maxillary artery, and the pterygoid venous plexus of veins. Intraoral bleeding accompanied by severe epistaxis in these cases makes it difficult to locate the precise bleeding focus. Eventual uncontrolled bleeding would require Merocel packing or surgical intervention. In general, a severe late postoperative hemorrhage is most effectively managed by angiography and embolization. Herein we describe a delayed hemorrhage case in which the cause was not evident on angiography. We were able to detect the bleeding point through an endoscopic nasal approach and treat it using direct cauterization.

• 아동학회지
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• 제33권1호
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• pp.237-259
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• 2012

The purpose of this study is to examine how children perceived the use of intelligent service robots in early childhood education and identifying the characteristics of the interaction between the children concerned and the robots. The subjects of this study were 49 kindergarten students from Girin Kindergarten in Gyeonggi-do. The results of this study suggested that the children personalized the robot and recognized it as their friend, regardless of their ages. In the interactions between the children and the robot, the children engaged in physical contact with the robot and occasionally tried to control its functions. In the child-robot interaction, the children searched their favorite functions and used them repeatedly, but also lost interest in those repeated functions. Regardless of their interest levels, however, the attendance or portfolio organization functions. With regard to the interaction between peers, there were frequent quarrels regarding the use of the robot at first, but these conflicts were resolved by the intervention of peers or teachers, and the children who were familiar with the use of the robot helped their friends; this was viewed as constituting cooperative behavior. Children usually used the robot with their friends. The robot was a medium for children to find new friends. Peer group activities were explored and new friendships were created as a result of the use of the robot.

• 대한가정학회지
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• 제46권1호
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• pp.117-129
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• 2008

In present study, using 1572 low-income families and 266 Head Start teachers from Family and Child Experiences Survey (FACES) in the U.S., we examined the effects of mothers' reading and the characteristics of interaction between teacher-child interaction on 4-and 5-year-olds' cognitive development represented by their verbal and numerical abilities. Frequencies of mothers' reading at home consistently predicted higher scores of children's Peabody Picture Vocabulary Test and Woodcock Johnson Applied Problems. Teachers' sensitivity and permissiveness in their interactions with children in classroom were positively related to children's verbal abilities and teachers' sensitivity predicted better numerical abilities of children after controlling for mothers' reading and the characteristics of family and teacher. The findings shed light on the contributions of teacher behaviors and familial factors to children's cognitive development calling for attention to the need for parent education on cognitively stimulating family environments and continuing education for early childhood teachers focusing on quality interactions with young children.

• Journal of Chest Surgery
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• 제18권4호
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• pp.605-614
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• 1985

The principal aim of surgery for congenital heart anomalies is the establishment of normal hemodynamic function. Palliative and corrective operations are selected with time to attain this end with minimal risk. In recent years, as operative mortality after primary total correction is lower than the mortality after early palliation and delayed correction, corrective operations in infants have increasingly supplanted palliative ones. Two hundred and eighteen infants below 10 kg with congenital heart anomalies underwent primary surgical intervention at Yonsei Medical Center from March 1979 to June 1985. There were 155 infants with VSD, 35 Infants with TOF, 5 infants with ECD, 4 infants with TGV, 3 infants with DORV, 3 infants with Pulmonary atresia, 3 infants with ASD and PDA, 2 infants with DOLV, and the remainders were Sinus Valsalva rupture, residual mitral regurgitation after total correction of ECD, PAPVR, Cor triatriatum, Truncus arteriosus, and Tricuspid atresia. The overall surgical mortality was 15.1%. In the acyanotic group, 13 infants died among 168 infants, and mortality was 7.7%. But in the cyanotic group, the mortality rate was very high and 20 infants died among 50 infants raising the mortality to 40.0%. These poor surgical results in the cyanotic or complicated group was due to inaccurate diagnosis, improper surgical methods and inadequate post-operative care which should be improved.

• Journal of Chest Surgery
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• 제29권12호
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• pp.1337-1341
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• 1996

계명대학교 의과대학 흉부외과학교실에서는 1989년 9월부터 1996년 3월까지 13명의 판막혈전증환자에서 16례의 재수술을 시행하였다. 연령분포는 32세부터 63세까지로 평균연령은 45.2세였으며 남여비는 1:2.3이었다. 판막치 환술후 재수술까지 걸린 기간은 평균 27.8개월이었으며 입원후 수술시까지 걸린 시간은 평균 33.5시간이 있다. 술전 UYHA 기능분류 4도가 12례(75%)였으며 이중 6례가 쇽상태 였다. 재수술은 판막치 환술이 15례, 혈전제거술만 시행한 경우가 1례있었다. 수술사망은 4례(25%)였으며 사망원인은 패혈증이 2례. 저심박출증이 2례였다. 술후 평균 30.3개월 추적조사하였고 술후 UYHA기능분류는 평균 1.2로 양호하였으며 만기 사망례는 없었다. 판막혈전증에 대한 재수술요법은 조기 진단하여 환자상태가 비교적 안정적일때 수술하는 것이 수술사망을 줄이는 방법으로 사료된다.