• Economic and Environmental Geology
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• v.47 no.1
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• pp.1-15
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• 2014

The Bobonaro m$\acute{e}$lange is one of the youngest syn-collisional m$\acute{e}$langes, located between the Indo-Australian and Eurasian plates. The m$\acute{e}$lange has formed in association with a collision between the Australian continental margin and the Banda arc initiated in Neogene. The Suai area at the southern part of Timor is a good place to examine the genetic relationship between the m$\acute{e}$lange and other rock sequences because various tectonostratigraphic units coexist in the area. In this study, we present the structural characteristics and spatial distribution of the Bobonaro m$\acute{e}$lange investigated as a part of 1:25K scale geologic mapping in the area, and discuss on the origin of the m$\acute{e}$lange. The Bobonaro m$\acute{e}$lange in the Suai area is composed of unmetamorphosed clay matrix and blocks of various lithologies. The clay matrix mainly is reddish brown or greenish gray in colour, and has scaly texture. Most blocks are allochthonous, but mostly derived from nearby formations. Based on the internal structure and relationship with surrounding rocks, the Bobonaro m$\acute{e}$lange is genetically classified into 1) diapiric m$\acute{e}$lange; 2) tectonic m$\acute{e}$lange; and 3) broken formation. The spatial distribution of the Bobonaro m$\acute{e}$lange indicates that it intruded all pre-collisional units including the lower Australian continental margin unit(Gondwana megasequence) and the Banda arc unit. Taking the field evidences and previous genetic models into consideration, the Bobonaro m$\acute{e}$lange is interpreted to be mainly formed as a diapiric m$\acute{e}$lange originated from Gondwana megasequence, consistently effected by faulting events. This study reflects that diapiric m$\acute{e}$lange is a significant component in recent accretionay-collision belts. It suggests that diapiric process should be considered as a main genetic factor even in ancient m$\acute{e}$lange.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.11a
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• pp.219-222
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• 2003

This paper is to propose e-business strategies for individual SME's(small and medium-sized enterprises). e-business maturity model is used to assess e-business maturity level of a target SME, and then corresponding e-business strategy is proposed based on the current maturity level. We studied two SME's to show how it works. Most SME's are small and do not have enough resources to invest on information systems. As it turns out, e-business strategies of SME should heavily depend on its relationship with customers and suppliers. One of the studied SME's is found to be in higher maturity level, because its manufacturing system is tightly related to its customer. One of major implications of this study is that e-business level of SME's should be upgraded considering how it is doing business with its customers and suppliers.

• Journal of Agricultural Extension & Community Development
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• v.8 no.1
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• pp.1-14
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• 2001

e-Learning has brought dramatic changes in education system for many companies in Korea. Many researchers and practitioners believe that e-Learning will be the main educational system for every companies in the world. e-Learning is an alternative education system, which includes computer based learning, web based learning, virtual classroom, and distance learning. e-learning has been expected to impact every educational sectors including Extension services. This study intends to identify and suggest some implications for successful e-Learning implementation of Extension education by investigating the successful factors of enterprises' e-Learning system, where outstanding results have be shown.

• Journal of Applied Biological Chemistry
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• v.51 no.1
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• pp.1-6
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• 2008

Estrogens, a group of steroid compounds functioning as the primary female sex hormone, play an important role in the development and progression of breast cancer. In this study, using a novel annealing control primer-based GeneFishing PCR technology, five differentially expressed genes (DEGs), expressed using 10nM mitogenic estrogens, $17{\beta}$-estradiol (E2) and $16{\alpha}$-hydroxyestrone ($16{\alpha}$-OHE1), were selected from the estrogen receptor (ER)-positive MCF-7 human breast cancer cells. The DEGs, MRPL42, TUBA1B, SSBP1, KNCT2, and RUVBL1, were identified by comparison with the known genes via direct sequencing and sequence homology search in BLAST. Quantitative real-time PCR data showed that two DEGs, tubulin ${\alpha}1b$ and kinetochore associated 2, were greater than 2-fold upregulated by E2 or $16{\alpha}$-OHE1. Both genes could be new biomarkers for the treatment and prognosis of cancers, and further study may provide insights into the molecular mechanisms underlying development and progression of breast cancer.

• Journal of Applied Biological Chemistry
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• v.50 no.4
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• pp.264-269
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• 2007

Root extracts of Angelica gigas and A. acutiloba have been used traditionally for the treatment of gynecological diseases, as well as anemia, blood stasis, and inflammatory pain, as blood tonics in Oriental medicine. In the present study, we investigated the effects of A. gigas and A. acutiloba on inflammatory mediators in mouse macrophages and compared their activities. Many studies suggest that prostaglandin $E_2$ ($PGE_2$) biosynthesis and nitric oxide (NO) production play important roles in the processes of both inflammation and carcinogenesis. Ethanolic extracts from the roots of both species exhibited significant inhibitory effects on $PGE_2$ generation in lipopolysaccharide-stimulated RAW 264.7 cells. In particular, the extract from A. gigas was more effective than that from A. acutiloba. Although neither inhibited NO generation, the extract from A. acutiloba stimulated NO generation. Our results suggest that the roots of A. gigas might possess more anti-inflammatory and/or cancer chemopreventative activity than that of A. acutiloba due to the suppression of cyclooxygenase-2 (COX2)-mediated $PGE_2$ production. In addition, A. acutiloba might exert anti-tumor activity through an increase in macrophage-produced NO.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.94-97
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• 2009

연 및 계절강수량의 정확한 예보는 수자원관리에 매우 중요하다. 예보 정확도를 높이기 위한 다양한 연구가 계속 진행되어 왔다. 그럼에도 불구하고 강수자료가 가지는 매우 큰 불확실성 때문에 예보의 정확도 향상은 계속되는 숙제로 우리에게 남아 있다. 이를 개선하기 위하여 본 연구에서는 군집화 기법을 이용한 연 및 계절 강수량 예측개선에 대한 연구 결과를 제시하였다. 이를 위하여 연강수량, 계절강수량 및 월강수량의 예측을 위하여 전구에서 일어나는 각종 기후 인자들과의 상관성 분석은 대단히 중요하다. 전 세계적으로 어느 특정 지역에서의 선행 기후인자 변화 양상이 우리나라의 강수량에 높은 상관성을 가지며 영향을 미친다면 예측을 위한 매우 유용한 정보라 하겠으나 국내 강수량과 기후 지수 사이의 선형 상관성은 매우 낮을 뿐만 아니라 지체상관성도 특정 지체에서 매우 큰 상관성을 보이는 인자를 찾기 어려움을 알 수 있다. 이를 극복하기 위하여 본 연구에서는 k-mean clustering을 이용하여 우리나라 주변의 기후조건을 분류하고 기후조건에 따른 강수량의 변화를 분석하였다. 남중국해역($105^{\circ}E\;^{\sim}\;135^{\circ}E$, $0^{\circ}N\;^{\sim}\;35^{\circ}N$), 우리나라 연안 해역 ($110^{\circ}E\;^{\sim}\;150^{\circ}E$, $20^{\circ}N\;^{\sim}\;40^{\circ}N$), 인도양 해역 ($75^{\circ}E\;^{\sim}\;105^{\circ}E$, $0^{\circ}N\;^{\sim}\;25^{\circ}N$) 및 아라비아 해역 ($45^{\circ}E\;^{\sim}\;75^{\circ}E$, $0^{\circ}N\;^{\sim}\;30^{\circ}N$ 평균 해수면 온도 변화에 따라 8개 군집으로 분류한 분석결과로 분석결과 2008년도는 그룹 5에 해당하며 그룹 5의 기후 상태는 근해와 남중국해역의 평균 해수면 온도가 평년보다 낮고 인도양 해역과 아라비아 해역의 평균 해수면 온도는 평년값과 비슷한 상태를 나타낸다. 그룹 5에 해당하는 기후조건에서 차년의 강수평균은 평년값 보다 적음을 보였다. 이러한 특성은 전체 유역에 걸쳐 동일하게 나타났다. 이에 대한 계절적 평균 분포는 군집 5에 대한 차년도 강수의 평균 계절분포는 전체적으로 평년값보다 낮게 나타났다. 이에 근거하여 올해 연 평균 강수량은 평년값보다 적을 것이며 전체 계절에 대하여도 평년값보다 적은 강수량이 올 것으로 판단된다. 이는 기상청의 2009년 봄철 기후전망과 유사한 예측 결과를 보여준다.

• Food Science of Animal Resources
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• v.27 no.3
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• pp.262-266
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• 2007

This study was carried out to compare the taste and nutrient characteristics of Hanwoo chilled sirloin and rump with Australian beef sirloin and rump. Vitamin A, vitamin E and cholesterol were highest in Hanwoo among the three breeds (p<0.05). With regard to hexane composition, the percentage of inosine monophosphate (IMP) was the highest in Hanwoo. In addition, the sensory scores were also highest from Hanwoo. These results indicated from Hanwoo had the most acceptable quality among the five breeds tested (vitamin A, vitamin E, cholesterol, hexane, and sensory test).

• Food Science of Animal Resources
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• v.37 no.4
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• pp.579-592
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• 2017

This study assessed the quantitative microbial risk of non-enterohemorrhagic Escherichia coli (EHEC). For hazard identification, hazards of non-EHEC E. coli in natural and processed cheeses were identified by research papers. Regarding exposure assessment, non-EHEC E. coli cell counts in cheese were enumerated, and the developed predictive models were used to describe the fates of non-EHEC E. coli strains in cheese during distribution and storage. In addition, data on the amounts and frequency of cheese consumption were collected from the research report of the Ministry of Food and Drug Safety. For hazard characterization, a doseresponse model for non-EHEC E. coli was used. Using the collected data, simulation models were constructed, using software @RISK to calculate the risk of illness per person per day. Non-EHEC E. coli cells in natural- (n=90) and processed-cheese samples (n=308) from factories and markets were not detected. Thus, we estimated the initial levels of contamination by Uniform distribution ${\times}$ Beta distribution, and the levels were -2.35 and -2.73 Log CFU/g for natural and processed cheese, respectively. The proposed predictive models described properly the fates of non-EHEC E. coli during distribution and storage of cheese. For hazard characterization, we used the Beta-Poisson model (${\alpha}=2.21{\times}10^{-1}$, $N_{50}=6.85{\times}10^7$). The results of risk characterization for non-EHEC E. coli in natural and processed cheese were $1.36{\times}10^{-7}$ and $2.12{\times}10^{-10}$ (the mean probability of illness per person per day), respectively. These results indicate that the risk of non-EHEC E. coli foodborne illness can be considered low in present conditions.

• Food Science of Animal Resources
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• v.39 no.6
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• pp.877-887
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• 2019

This study was performed to determine changes in mutagenicity and biogenic amine concentrations in sausages fermented with six different starter cultures treated with vitamins C and E. Six different types of fermented sausages with different combination of starter cultures were manufactured. T1, Pediococcus acidilactici; T2, P. pentosaceus and Staphylococcus carnosus; T3, S. carnosus, S. xylosus, Debaryomyces hansenii, Lactobacillus curvatus, and P. pentosaceus; T4, S. carnosus and L. sakei; T5, S. xylosus and L. plantarum; and T6, Penicillium nalgiovensis. After treatment with vitamins C and E in fermented sausages, changes in mutagenicity and biogenic amine concentrations were measured. The sausages fermented with Staphylococcus xylosus and Lactobacillus plantarum starter cultures showed the most effective antimutagenic activity (p<0.05). The mutagenicity was further decreased in the sausages treated with vitamins C and E (p<0.05), regardless of the starter cultures. The use of Pediococcus acidilactici, S. xylosus, L. plantarum, and Penicillium nalgiovensis as starter cultures was effective in decreasing biogenic amine concentrations (p<0.05). In addition, vitamin E was more effective in decreasing the biogenic amine concentrations than vitamin C. In conclusion, we recommend the use of S. xylosus and L. plantarum as starter cultures, in addition to the use of vitamins C and E, to reduce the potential risk of meat mutagens in fermented sausages.

• Korean Journal of Plant Resources
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• v.30 no.1
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• pp.17-21
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• 2017

Since the acetylcholinesterase (AChE) inhibitor is used to treat Alzheimer's disease, the present study aimed to analyze the component with anti-AChE activity from the essential oil of Artemisia iwayomogi (Compositae). The four major components of the essential oil were identified to be camphor (29.8%), borneol (28.0%), eucalyptol (5.81%) and coumarin (5.49%) from a gas chromatography-mass spectrometry (GC-MS). The essential oil and its three components, camphor, borneol, and coumarin, were subjected to anti-AChE assay. The $IC_{50}$ values of the essential oil and coumarin were shown to be $0.298mg/m{\ell}$ and $0.236mg/m{\ell}$, though those of other two components, camphor and borneol, were more than $0.250mg/m{\ell}$. These results suggest that coumarin is an active substance of this essential oil with anti-AChE activity.