• 미생물학회지
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• 제52권1호
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• pp.59-64
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• 2016

본 연구에서는 차세대 염기서열분석(pyrosequencing) 기술을 이용해 조릿대(Sasa borealis) 대나무림의 낙엽층과 근권 토양 내 주요 군집인 방선균군집의 계통학적 특성을 분석하여 방선균 유전자원 다양성 확보를 위한 기반 연구를 수행하고자 하였다. 낙엽층 시료 내 세균군집은 2,588 OTUs, 다양성 지수 7.55로 나타났으며, 근권토양 시료의 경우 2,868 OTUs, 다양성 지수 8.15로 다양한 세균군집이 균등하게 분포하고 있는 것으로 확인되었다. 대나무림 토양시료 내 세균군집은 총 35개의 문으로 구성되었으며, Proteobacteria (51-60%), Bacteroidetes (16-20%), Acidobacteria (4-16%) 그리고 Actinobacteria (4-14%) 계통군이 주요 세균군집으로 확인되었다. 특히, Actinobacteria은 총 6목 35과 121속의 다양한 방선균이 분포하였으며, 전체 방선균군집의 83%가 Actinomycetales 목으로 확인되었다. 이들 Actinomycetales 목은 28개 과로 구성되었으며, Micromonosporaceae, Pseudonocardiaceae 그리고 Streptomycetaceae는 조릿대 대나무림의 낙엽층과 근권토양에서 풍부도가 가장 높고 변이가 적은 대표 방선균군집으로 확인되었다.

• 한국약용작물학회지
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• 제23권5호
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• pp.400-405
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• 2015

Background : As the characterization of medicinal plants is an important aspect of traditional Asian herbal medicine, this study examines the morphological and anatomical characteristics in four fructus form medicinally important plants belonging to the family Apiaceae. Methods and Results : Fruit morphology of four genera was examined using microtome sections and light microscopy. The Anethi Fructus, Anethum graveolens (Siraja) has unique wing-like and membranous lateral ribs that are, approximately $500{\mu}m$ wide. The Coriandri Fructus, Coriandrum sativum (Hoyuja) does not have oil ducts at the dorsal region of the mericarp and differs in the development of the dorsal ribs. The ribs appear upon drying and therefore, consist of primary and secondary ribs. The Foeniculi Fructus, Foeniculum vulgare (Hoehyang) characteristically develops three dominant dorsal ribs and has a strong aromatic fragrance. Finally, the Cnidii Fructus, Torilis japonica (Sasangja) has many oil ducts at the dorsal and carpophores regions and develops many hooked trichomes one the fructus surface. Conclusions : We conclude from this study that each plant has several prominent and distinguishing morphological and anatomical characteristics. Therefore, fruit morphology is very useful for identifying these medicinal plants. In addition, the correct use and herbal name need to be standardized for plants used traditionally in Asian medicine within Korea, China, and Japan.

• Journal of Microbiology and Biotechnology
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• 제22권3호
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• pp.311-315
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• 2012

A novel ${\beta}$-proteobacterium, designated BXN5-$27^T$, was isolated from soil of a ginseng field of Baekdu Mountain in China, and was characterized using a polyphasic approach. The strain was Gram-staining-negative, aerobic, motile, non-spore-forming, and rod shaped. Strain BXN5-$27^T$ exhibited ${\beta}$-glucosidase activity that was responsible for its ability to transform ginsenoside $Rb_1$ (one of the dominant active components of ginseng) to compound Rd. Phylogenetic analysis based on 16S rRNA gene sequences showed that this strain belonged to the family Comamonadaceae; it was most closely related to Ramlibacter henchirensis $TMB834^T$ and Ramlibacter tataouinensis$TTB310^T$ (96.4% and 96.3% similarity, respectively). The G+C content of the genomic DNA was 68.1%. The major menaquinone was Q-8. The major fatty acids were $C_{16:0}$, summed feature 4 (comprising $C_{16:1}$ ${\omega}7c$ and/or iso-$C_{15:0}$ 2OH), and $C_{17:0}$ cyclo. Genomic and chemotaxonomic data supported the affiliation of strain BXN5-$27^T$ to the genus Ramlibacter. However, physiological and biochemical tests differentiated it phenotypically from the other established species of Ramlibacter. Therefore, the isolate represents a novel species, for which the name Ramlibacter ginsenosidimutans sp. nov. is proposed, with the type strain being BXN5-$27^T$ (=DSM $23480^T$ = LMG $24525^T$ = KCTC $22276^T$).

• 한국수산과학회지
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• 제35권2호
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• pp.105-109
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• 2002

1994년 6월에서 1995년 5월 사이 광양만 대도 주변의 잘피밭에서 Epifaunal sampler를 이용하여 매달 바다대벌레류를 채집하여 종조성과 계절변동을 조사하였다. 조사기간 동안 총 1과 1속 6종의 바다대벌레류가 출현하였다. 그 중 짧은팔바다대벌레 (Caprella tsugarensis)와 허리갈고리바다대벌레 (Csprella kroeyeri)가 각각 전체 개체수의 $53.9\%$와 $32.1\%$를 차지하며 우점하였다. 출현 종수, 개체수 모두 이른 여름철에 높았고 가을과 겨울철에는 낮아져 뚜렷한 계절변동을 보였다. 이러한 바다대벌레류의 계절변동은 잘피의 생체량 변동과 밀접한 관련을 보였다. 또한 어류의 포식압과도 연관이 있는 것으로 추정된다.

• The Korean Journal of Ecology
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• 제21권1호
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• pp.97-103
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• 1998

Yedang lake has so plentiful pondage and many species of fresh-walter-fish that a large number of people crowd around there all the year round. Most of them are not used to prevent tsutsugamushi disease spreading by chigger(T-mite). Accordingly, this study was carried out in order to obtain basic materials for prevention of this disease and the results are summarized as follows. The number of wild rat that captured in surveyed areas was sixty five(apodemus agrarius: 63, Rattus norvegicus: 2) during the period of a year and ration of captured rats to trap was about 8%. The dominant species of T-mite in all the surveyed areas were Leptotrombidium pallidum and L. palpale and the total number collected was 5782.9 with one family, two genra, eight species. The density of T-mites that collected from rats in three areas(Nodongri, Hatanbangri, Kyochonri) appeared $743.3{\pm}80.4,\;847.2{\pm}86.2\;and\;869.6{\pm}86.4,\;and\;in\;soil\;149.5{\pm}13.9,;154.7{\pm}14.7\;and\;182.4{\pm}20.8$ respectively. On the whole, the number of T-mite that collected from the rats was about three times as much as it in soil. The comparison of individual number of T-mite per a rat collected in three surveyed sites(A,B and C) showed 126.7, 243.1, 258.6 and per $2,000cm^3$ of soil 12.7, 12.7, 54.6, 103.5 respectively. In other word, the number of T-mite at site A and B is smaller than that at area C, thus comparing habitats of three sites each other, C is better living environment of rat and mite than that of A or B. Seasonl occuarance of t-mite that is from rat gradually was increased toward winter and showed the peak to January, and decreased since March but it in soil was inverse proportion to it from rats, because the larvae of T-mite that was hatched in soil was transmited to host in order to suck the body fluid.

• Tuberculosis and Respiratory Diseases
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• 제72권1호
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• pp.50-54
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• 2012

Hereditary hemorrhagic telangiectasia (HHT, Osler-Weber-Rendu disease) is a rare autosomal dominant disease characterized by heterogenous multisystemic dysplasia of the vascular tissue. Prevalence of HHT is 1 in 5,000~8,000. HHT commonly presents with recurrent epistaxis, but may have more serious consequences if visceral vascular beds are involved. Approximately 30~50% of HHT cases also present with pulmonary arteriovenous malformation (PAVM). Spontaneous hemothorax is less common, and PAVM is one of the causes leading to hemothorax. Our case involved an 18-year-old female who had suddenly developed right chest pain. The reason for chest pain was due to right spontaneous hemothorax accompanied by PAVM in the right middle lobe. The patient was additionally diagnosed with HHT upon examination of her family history, specifically through her mother's symptom that included recurrent epistaxis and mucosal telangiectasia.

• 한국응용곤충학회지
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• 제39권1호
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• pp.13-19
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• 2000

유자과원에 발생하는 주요해충인 귤응애의 생물적 방제를 위해 천적의 종류 및 주요 포식성 천적의 시기별 발생량을 '96년부터 '98년까지 3년동안 전남 고흥지역에서 조사하였다. 귤응애의 천적으로는 Oligota kashimirica benifica, 깨알반날개(O. yasumatsui), 꼬마무당벌래(Stethorus punctillum), 칠성풀잠자리붙이 (Chrysopa pallens), 꼬마남생이무당벌레(Propylea japonica), 애꽃노린재(Orius sauteri), 응애총채벌레(Scolothrips takahashii), 긴털이리응애(Amblyseius womersleyi) 그리고 관총채벌레류 1종으로 총 5목 7과 9종이 조사되었으며, 이 중 우점천적은 깨알반날개류와 꼬마 무당벌레였다. 유자과원에서 깨알반날개류는 5월 중순부터 11월 중순까지 발생하며 년 4~5세대를 경과하였고, 4세대인 9월 상순에 연중 최대발생량을 보였다. 꼬마무당별레는 5월 하순부터 10월 하순까지 발생하며 년 3세대 경과하였고 6월 하순~7월 중순에 발생최성기를 보였다. 먹이인 귤응애와 포식자인 천적의 시기별 밀도변동을 볼 때 9월까지는 귤응애의 발생상황에 따라서 포식자의 발생밀도도 증감하는 시기적 일치 경향을 보였으나, 10월 이후 귤응애의 밀도가 증가하는 반면에 포식자의 밀도는 급격히 감소하여 불일치 현상이 나타났다.

• 융합정보논문지
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• 제7권5호
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• pp.149-155
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• 2017

본 연구의 목적은 최근 한국 사회복지 분야의 여성 관련 연구 동향을 고찰함으로써 향후 연구를 위한 방향을 제공하는 데 있다. 본 연구는 본 주제에 관한 선행 연구 결과를 기반으로 새로운 연구 결과들을 축척함으로써 사회복지 지식의 지평을 넓히는 차원에서 이론적 중요성을 갖는다. 내용 분석을 사용하여 2009~2017년 한국사회복지학에 게재된 여성 관련 논문 37편들을 연구 대상, 연구 주제와 연구 방법들을 중심으로 분석하였다. 연구 대상에 관한 분석 결과, 여성에 관한 사회복지 연구에서 여성은 클라이언트, 가족과 근로자로서 재현되고 있는 것으로 나타났다. 연구 주제를 분석한 결과 다음과 같은 총 13개의 주제들이 도출되었다: 가족과 가정, 사회적응, 트라우마 관련, 노동, 사회 복지 서비스 관련, 사회/지역사회 참여, 프로그램 또는 척도 개발, 자립, 결혼 관련, 젠더 차이, 젠더, 양성 평등 및 기타. 또한 연구 방법론 측면에서는 실증적 연구 방법론이 대다수로 나타났다. 향후 연구에서는 연구 대상, 주제 및 방법론에 있어 범위를 넓히기 위한 학문적 노력이 필요하다고 하겠다.

• Annals of Clinical Neurophysiology
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• 제7권2호
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• pp.65-74
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• 2005

Charcot-Marie-Tooth (CMT) disease was described by Charcot and Marie in France and, independently, by Tooth in England in 1886. CMT is the most common form of inherited motor and sensory neuropathy, and is a genetically heterogeneous disorder of the peripheral nervous system. Therefore, many genes have been identified as CMT-causative genes. Traditionally, subclassification of CMT have been divided into autosomal dominant inherited demyelinating (CMT1) and axonal (CMT2) neuropathies, X-linked neuropathy (CMTX), and autosomal recessive inherited neuropathy (CMT4). Recently, intermediate type (CMT-Int) with NCVs between CMT1 and CMT2 is considered as a CMT type. There are several related peripheral neuropathies, such as $D{\acute{e}}j{\acute{e}}rine$-Sottas neuropathy (DSN), congenital hypomyelination (CH), hereditary neuropathy with liability to pressure palsies (HNPP) and giant axonal neuropathy (GAN). Great advances have been made in understanding the molecular basis of CMT, and 17 distinct genetic causes of CMT have been identified. The number of newly discovered mutations and identified genetic loci is rapidly increasing, and this expanding list has proved challenging for physicians trying to keep up with the field. Identifying the genetic cause of inherited neuropathies is often important to determine at risk family members as well as diagnose the patient. In addition, the encouraging studies have been published on rational potential therapies for the CMT1A. Now, we develop a model of how the various genes may interact in the pathogenesis of CMT disorder.

• Molecules and Cells
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• 제22권3호
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• pp.353-359
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• 2006

The bone morphogenetic protein (BMP) family has been implicated in control of cartilage development. Here, we demonstrate that BMP-2 promotes chondrogenesis by activating p38 mitogen-activated protein kinase (MAPK), which in turn downregulates $Wnt-7a/{\beta}$-catenin signaling responsible for proteasomal degradation of Sox9. Exposure of mesenchymal cells to BMP-2 resulted in upregulation of Sox9 protein and a concomitant decrease in the level of ${\beta}$-catenin protein and Wnt-7a signaling. In agreement with this, the interaction of Sox9 with ${\beta}$-catenin was inhibited in the presence of BMP-2. Inhibition of the p38 MAPK pathway using a dominant negative mutant led to sustained Wnt-7a signaling and decreased Sox9 expression, with consequent inhibition of precartilage condensation and chondrogenic differentiation. Moreover, overexpression of ${\beta}$-catenin caused degradation of Sox9 via the ubiquitin/26S proteasome pathway. Our results collectively indicate that the increase in Sox9 protein resulting from downregulation of ${\beta}$-catenin/Wnt-7a signaling is mediated by p38 MAPK during BMP-2 induced chondrogenesis in chick wing bud mesenchymal cells.