• 제목/요약/키워드: disease pattern

검색결과 1,483건 처리시간 0.042초

Conotruncal 기형 평가에서 전자선 단층 촬영 (EBT)의 정확성 (Evaluation of Conotruncal Anomalies by Electron Beam Tomography)

  • 최병욱;박영환;최병인;최재영;김민정;유석종;이종균;설준희;이승규
    • Journal of Chest Surgery
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    • 제33권4호
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    • pp.290-300
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    • 2000
  • Background: To evaluate the diagnostic accuracy of EBT(Electron Beam Tomography) in the diagnosis of conotruncal anomaly and to determine whether it can be used as a substitute for cardiac angiography. Material and Method: 20 patients(11M & 9F) with TOF(n=7, pulmonary atresia 2), DORV(n=7), complete TGV(n=4), & corrected TGV(n=2) were included. The age ranged from 7 days to 26 years(median 60 days). We analyzed the sequential chamber localization, the main surgical concenrn in each disease category (PA size, LVED volume and coronary artery pattern for TOF & pulmonary atresia, the LV mass, LVOT obstruction, coronary artery pattern for complete TGV, and type of VSD and TV-PV distance for DORV, etc) and other associated anomalies(e.g., VSD, arch anomalies, tracheal stenosis, etc). Those were compared with the results of echocardiography(n=19), angiography (n=9), and surgery(n=11). The interval between EBT and echocardiography/angiography was within 20/11 days, respectively except for an angiography in a patient with corrected TGV (48 days). Result: EBT correctly diagnosed the basic components of conotruncal anomalies in all subjects, compared to echocardiography, angiography or surgery. These included the presence, type and size of VSD(n=20), pulmonic/LV outflow tract stenosis(n=15/2), relation of great arteries and the pattern of the proximal epicardial coronary arteries(16 out of 20). EBT proved to be accurate in quantitation of the intrapericardial and hilar pulmonary arterial dimension and showed high correlation and no difference compared with echocardiography, angiography, or surgery(p>0.05) except for left pulmonary arterial & ascending arterial dimension by echocardiography. LVED volume in seven TOF(no difference: p>0.05 & high correlation: r=0.996 with echocardiography), and LV mass in 4 complete TGV were obtained. Additionally, EBT enabled the cdiagnosis of subjlottic tracheal stenosis and tracheal bronchus in 1 respectively. Some peripheral PA stenosis were not detected by echocardiography, while echocardiography appeared to be slightly more accurate than EBT in detecing ASD or PDA. Conclusion: EBT can be a non-invasive and accurate modality of for the evaluation of most anatomical alteration including peripheral PS or interruption in patients with conotruncal anomalies. Combined with echocardiography, EBT study provides sufficient information for the palliative or total repair of anomalies.

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모로코인(人)의 장신구(裝身具)와 화장(化粧)에 관(關)한 연구(硏究) (A Study of the Personal Ornaments and Make-up of Maroccan)

  • 이순홍
    • 패션비즈니스
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    • 제5권2호
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    • pp.15-34
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    • 2001
  • Ornaments are accessories for the decoration of the body or dress. They aren't unavoidably required one, but serve to make one's dress perfect as decorative industrial art objects. In Morocco, ornaments were initially used as a sign of social position or the class or an incantatory symbol. In effect, they were originally employed to adjust one's dress, not just for decoration, and they were of use for household economy. Gold, silver and handcraft available for exchange were a means of increasing one's property and an indication of social standing and wealth. In particular, the dress and jewelry of a bride was a measure of her family's wealth, regarded as a symbol of her chastity and value. The ornaments symbolically back up people's faith in supernatural power, and their real value is based on implicit form or way of decoration, not the external shape. Specifically, there is a tendency to use the form of animal as a protector, not one to frighten people. In the artistic tradition of Morocco, fish pattern stands for water and rain, and eagle and bird are considered to be related to fate. Scorpion and lizard are depicted as an inquirer of sun, and snake is a symbol of abundance and sexual instinct, being viewed to have an ability to cure disease. Turtle pattern is a symbol of saint because it protects one from the evil. The ornaments are made of gold, silver, amber, clam, garnet, glass, nielle, enamel, glaze, coral or tree, and symbolic patterns are used, including hand(a symbol of five numerals), turtle, lizard, scorpion, eye, triangle, bird and eggs. They are very big and diverse, being categorized into ornaments for the head or the chest, neckless, fibula, earring, bracelet and ring. For Moroccans, make-up is a sort of instinctive behavior to meet aesthetic and sexual desire. They also wear make-up for practical purpose of protection, intentionally inflict a wound on the skin for ceremonial or religious purpose, paint the skin with pigment, or have the part of the body tattooed for incantatory purpose. All this actions are regarded as make-up. The raw material of cosmetics is aker, a vegetable dye. They get the lips or cheeks turn red and paint eyebrows with yellow saffran powder to have a bad devil lose its strength. Tattooing is mainly done by women and viewed as a sign of their value or social organization they belong to. Sometimes that is used to represent a woman's being old enough to marry or getting married already or the frequency of marriage. Besides, tattoo is believed to prevent or remedy loose bowels or cough, depending on its location or pattern, and they often change tattoo according to the change of beauty art.

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The Correlation between Caudal Epidurogram and Low Back Pain

  • Jo, Dae-Hyun;Jang, Sul
    • The Korean Journal of Pain
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    • 제25권1호
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    • pp.22-27
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    • 2012
  • Background: The common causes of lower back pain with or without leg pain includes disk disease and spinal stenosis. A definitive diagnosis is usually made by means of magnetic resonance imaging (MRI), but treatment is often difficult because the MRI findings are not consistent with the symptoms of the patient in many cases. The objective of this study was to observe the correlation between the patterns of epidurography performed in patients having lower back pain with or without leg pain and the position or severity of the pain as subjectively described by the patients. Methods: The subjects of this study were 69 outpatients with lower back pain with or without leg pain who visited our clinic and complained of predominant pain on one side. We performed caudal epidural block using an image intensifier. A mixture of the therapeutic drug and the contrast agent (10 ml) was injected to observe the contrast flow pattern. The patients who complained of predominant pain on one side were divided into the left side group and the right side group. A judgment of inconsistency was made if the contrast agent flowed to the side of the pain, while a judgment of consistency was made if the contrast agent flowed to the opposite side of the pain. The degree of the drug distribution was evaluated by counting the number of cells to which the contrast agent's flowed for evaluating the correlation between the contrasted cell and the severity of pain (one group ${\leq}$ VAS 7, the other group ${\geq}$ VAS 8) the degree of the contrast agent's contrast was evaluated by dividing and counting an image into 15 cells (the left, right, and middle sections at each level of L4, L5, S1, S2, and S3). Results: Thirty out of the 69 patients who had laterality in pain, that is, those who complained of predominant pain on one side, showed that the laterality of the pain and the contrast agent flow was consistent, while 39 patients showed that the laterality was inconsistent (P: 0.137). The evaluation of the correlation between the pain and the contrast agent flow showed that the mean number of contrasted cells was $9.0{\pm}2.2$ for the 46 patients in the group with a VAS of 7 or lower and $6.5{\pm}2.0$ for the 23 patients in the group with a VAS of 8 or higher, indicating that the former group showed a significantly greater number of contrasted cells (P < 0.001). Conclusions: This study, conducted with patients having lower back pain with or without leg pain, showed that the contrast flow pattern of caudal epidurography had a significant correlation with the severity of the pain but not with the laterality of the pain.

CD206+ dendritic cells might be associated with Heat-pattern and induced regulatory T cells after treatment with bee venom

  • Jung, Woo-Sang;Kwon, Seungwon;Yang, Jung Yun;Jin, Chul;Cho, Seung-Yeon;Park, Seong-Uk;Moon, Sang-Kwan;Park, Jung-Mi;Ko, Chang-Nam;Bae, Hyunsu;Cho, Ki-Ho
    • 대한한의학회지
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    • 제43권2호
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    • pp.1-7
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    • 2022
  • Objectives: Bee venom (BV) is a widely used therapy in Traditional East Asian Medicine (TEAM). We previously reported that BV was clinically effective for treating Parkinson's disease, that phospholipase A2 (PLA2) was the main component of BV, and that it induced regulatory T cells (Tregs) by binding CD206 on dendritic cells (DCs). Therefore, we aimed to reconfirm our findings in human blood samples and investigate the relationship between CD206+ DCs and clinical syndrome differentiation in TEAM. Methods: We surveyed 100 subjects with questionnaires on cold-heat patternization and obtained their blood samples. The obtained human peripheral blood monocytes (hPBMCs) were washed with phosphate-buffered saline (PBS). After resuspension with ex vivo media, numbers of cells were counted. Tregs were counted after culturing the samples in a 37℃ CO2 incubator for 72 h. Results: We divided the subjects into a relatively high CD206+ group or a relatively low CD206+ group. The heat factor scores of high CD206+ group were significantly higher than that of low CD206+ group (high vs low: 239.2 ± 54.1 vs 208.4 ± 55.1, p=0.023). After culturing with PLA2, Tregs increased in the high CD206+ group but decreased in the low CD206+ group. Conclusion: In this study, we reconfirm that CD206+ DCs induced Treg differentiation by incubating human blood samples with PLA2 and that they showed an association with syndrome differentiation, especially with heat patterns, in TEAM. A heat pattern in TEAM might be one indication for PLA2 therapy because its score was elevated in the high CD206+ group.

Prognosis of tongue squamous cell carcinoma associated with individual surgical margin and pathological features

  • Cho, Seongji;Sodnom-Ish, Buyanbileg;Eo, Mi Young;Lee, Ju Young;Kwon, Ik Jae;Myoung, Hoon;Yoon, Hye Jung;Kim, Soung Min
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제48권5호
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    • pp.249-258
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    • 2022
  • The specific muscular structure of the tongue greatly affects margin shrinkage and tumor invasion, making the optimal surgical margin controversial. This study investigated surgical margin correlated prognosis of TSCC (tongue squamous cell carcinoma) according to margin location and its value, and the histopathologic factors which are suggestive of tumor invasion. And we would like to propose defining of the surgical margin for TSCC via prognosis according to location and margin values. We reviewed 45 patients diagnosed with TSCC who visited Seoul National University Dental Hospital (SNUDH) (Seoul, Republic of Korea) from 2010 to 2019, who were managed by a single surgical team. Patient clinical and pathological data of patients were retrospectively reviewed, and in 36 out of 45 patients, the pathologic parameters including the worst pattern of invasion (WPOI) and tumor budding were investigated via diagnostic histopathology slide reading. When standardized with as 0.25 cm anterior margins, as 0.35 cm deep margin, there was no significant difference in disease specific survival (DSS) or loco-regional recurrence-free survival (LRFS). Additionally, there was a non-significant difference in DSS and LRFS at the nearest margin of 0.35 cm (PDSS=0.276, PLRFS=0.162). Aggressive WPOI and high tumor budding showed lower survival and recurrence-free survival, and there were significant differences in close margin and involved margin frequencies. In TSCC, the value and location of the surgical margin did not have a significant relationship with prognosis, but WPOI and tumor budding suggesting the pattern of muscle invasion affected survival and recurrence-free survival. WPOI and tumor budding should be considered when setting an optimal surgical margin.

설문지(設問紙)에 의한 사상체질(四象體質) 판정(判定)의 일치도(一致度) 분석(分析) (Analysis of Inter-Questionnaire Agreement in Determining Sasang Constitution)

  • 박성식;박은경;최재영
    • 사상체질의학회지
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    • 제11권1호
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    • pp.103-117
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    • 1999
  • 1. 연구배경 및 목적 : 사상의학은 사람의 체질을 넷으로 나누면서부터 출발한다. 그러나 체질을 판별하기 위해서는 사진(四診)을 중심으로 종합적으로 판단하게 되어 있어 객관성이 부족하기 쉽다. 체질을 객관적으로 진단하기 위한 여러 가지 방법 중에서 자기보고식 설문조사법이 일반적으로 많이 사용되고 있다. 그러나 설문조사법도 설문지의 종류에 따라서 다른 결과를 나타내는 경우가 많다. 본 연구는 사상체질을 진단하기 위해 사용되는 설문지별 체질분포 특성과 설문지간의 판정 일치도를 비교 분석하여 설문지로 사상체질 유형을 가려내는데 도움을 주고자 하였다. 2. 방법 1997년부터 1999년까지 특별한 질병이 없는 한국인 1595명(단QSCC I은 348명)을 대상으로 하여 사상변증내용설문조사지(I), 사상체질분류검사 I(QSCC I), 사상체질분류검사II(QSCCII)의 세가지 설문지를 작성하게 하여 그 결과를 비교하였다. 3. 연구결과 및 결론 : 체질분포 특성은 사상변증내용설문조사지(I)은 소음인(55.9%), 태음인(21.2%), 소양인(12.8%), 태양인(3.9%)의 순서를 보였고, 사상변증내용설문조사지(I)을 판별식을 이용하여 재분석한 결과에서는 태음인(39.1%), 소음인(33.6%), 소양인(27.3%)의 순서로 체질분포 경향을 보였다. QSCC I에서는 소양인(559.1%), 태양인(34.8%), 태음인(5.6%), 소음인(0.6%)의 순서를 보였고, QSCCII에서는 태음인(34.8%), 소음인(34.7%), 소양인(30.5%)의 순서로 체질분포 경향을 보였다. 체질판정 일치율은 사상변증내용설문조사지(I)과 이 자료를 판별식을 이용하여 판별한 결과가 제일 높았으나 이것은 동일 설문지를 재분석한 것이며, 다음은 사상변증내용설문조사지(I)의 판별식에 의한 분석법과 QSCCII의 일치율이 55.6%로 높게 나타났다. 설문지를 이용하여 체질을 임상적으로 진단할 때는 사상변증내용설문조사지(I)을 판별식을 이용한 결과와 QSCCII의 결과를 함께 참고하여 체질진단에 이용하는 것이 가장 타당한 방법이라고 생각되며, QSCC I을 체질진단에 이용하는 것은 바람직하지 않은 것으로 나타났다.

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처음 진단된 두경부 선양낭성암종에서 $^{18}F$-FDG PET/CT: 임상상 및 병리소견과의 상관성 ($^{18}F$-FDG PET/CT in Patients with Initially Diagnosed Adenoid Cystic Carcinoma of the Head and Neck: Clinicoplathologic Correlation)

  • 이지영;최준영;고영혜;백정환;손영익;조숙경;천미주;이경한;김병태
    • Nuclear Medicine and Molecular Imaging
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    • 제43권5호
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    • pp.395-401
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    • 2009
  • 목적: 처음 진단된 두경부 선양낭성암종의 $^{18}F$-FDG PET/CT의 영상소견을 선양낭성암종의 병리적 소견, 병기 결정, 가장 흔한 두경부암인 편평세포암종의 $^{18}F$-FDG 섭취 양상, 예후와 상관 지어 알아보았다. 대상 및 방법: 두경부 선양낭성암종으로 처음 진단되어 $^{18}F$-FDG PET/CT를 시행한 16명의 환자가 대상이었다. PET/CT의 병기 결정 능력을 알아보고, 두경부 선양낭성암종의 $SUV_{max}$를 원발종양의 조직학적 아형(고형 대 관상형/사상형상), 병변의 크기와 일치하는 두경부 편평세포암종의 $SUV_{max}$, 무병생존율과 비교하였다. 결과: 16명의 환자들 중, 관상형 또는 사상형을 가진 군은 10명이었고 나머지 6명은 고형을 가진 군이었다. 고형 선양낭성암종의 $SUV_{max}$는 관상형 또는 사상형 선양낭성암종 보다 유의하게 높았다($6.7{\pm}3.2$ vs. $4.2{\pm}0.9$, p=0.03). $^{18}F$-FDG PET/CT로 기존 영상법에서 발견하지 못한 원격 전이를 18.7%의 환자에서 발견하여, 치료방침 변경에 기여하였다. 선양낭성암종의 $SUV_{max}$는 병변 크기가 같은 편평세포암종과 비교해 보았을 때 유의하게 낮았다($5.1{\pm}2.4$ vs. $13.6{\pm}6.0$, p<0.001). 조직학적 아형에 따른 무병생존율은 통계적으로 유의한 차이를 보이지 않았다. 반면에, 원발종양의 $SUV_{max}$가 6.0 이상인 환자들의 무병생존율은 $SUV_{max}$가 6.0 미만인 환자들보다 유의하게 낮았다(p=0.002). 결론: 두경부 선양낭성암종의 $^{18}F$-FDG 섭취양상은 조직학적 아형과 무병생존율과 유의한 관계가 있다. $^{18}F$-FDG PET/CT는 기존 영상법에서 발견하지 못한 원격전이 진단에 유용한 것으로 보인다. 사상형상 또는 관상형선양낭성 암종의 $^{18}F$-FDG 섭취는 낮을 수 있어, 선양낭성암종이 의심되지 않은 환자들의 PET영상 판독에 주의가 필요하다.

만성환아의 가족에 관한 국내 연구논문 분석 (An Analysis of Nursing Research on the Family with chronfcally ill children in Borea)

  • 정연;이군자;백승남;조결자
    • Child Health Nursing Research
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    • 제2권1호
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    • pp.69-92
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    • 1996
  • The purpose of study was : 1) to analyze the trend of research on the family with chronically ill children in Korea, 2) to suggest direction for future study on the family with chronically ill children, and contributing to the use of intervention in family nursing practice. Research studies on the family with chronically ill children were selected from the Korean Nusre, the Korean Nurses' Academic Society Journal, and from dissertations, which were conducted between 1975 and 1995. The total numbers of the studies were 35. These studies were analyzed for 1)time of publication or presentation, 2)research design, 3)characteristics of subjects, 4) type of chronic disease, 5)main concepts, 6)measurement tool, 7) the sis for a degree or nondegree, 8) result of correlational studies. The findings of the analysis were as follows : 1) The numbers of studies on the family with chronically ill children have increas rapidly the early 1990's. In research design, the numbers of survey research studies were the highest. Especially, the most frequently research design was the correlational survey. There were 19 correlational studies(25.7%) during the early 1990's. 2) The subjects in 16 studies(45.7%) were mother of chronically ill children and, in 8 studies (22.9% ) were their parents. 3) In most types of chronic diseases, there were 14 hematooncologic disease(32.6%) and 14 hadicapped children (32.6% ). 4) Frequently used research concepts were stress, degree of coping or way of coping, social support, parents' support, family functioning, intensity of family and family adaptation. 5) Acceding to the results of correlational studies, the more family stress was higher the more degree of coping, family functioning, intensity of family and degree of family adaption was lower. The more degree of social support was higher the more stress was lower and degree of coping, family functioning and intensity of family was higher. The more family functioning was higher the more intensity of family and family adaptation was higher. 6) 24 researches on the family with chronically ill children were done for a thesis for a degree and 11 were nondegree research studies. The following suggestions are made based on the above findings : 1) The pattern of these studies related to the family with chronically ill children in domain of Nursing need to be compared with trend in other domains. 2) More replicated research on the family with chronically ill children is needed to develop family nursing intervention and prove the effect of that and more qualitative research on the family with chronically ill children is needed to comprehensive indepth the family with chronically ill children. 3) Further research on the family with chronically ill children is needed to verify subjects and type of chronic disease, develop applicable measurement tools in Korea and identify relation between other concepts. 4) Family nursing researchers should make an effort to apply research result in various clinical settings and community settings, and try to carry out not only team research with clinical nurse but also other multidisciplinary researcher related to the family.

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개에서 미만성 간장병변의 정량적 진단을 위한 초음파 및 방사선학적 평가 (Ultrasonographic and radiographic evaluation for the quantitative diagnosis of diffuse hepatic disease in dogs)

  • 성재기;이희천;윤정희;이영원;안용주;최호정;최지혜
    • 대한수의학회지
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    • 제38권4호
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    • pp.918-928
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    • 1998
  • The present study was done with two aims. First, to evaluate the radiographic measurements of liver volumes in normal and hepatomegaly dogs induced by carbon tetrachloride. Second, to investigate quantitative tissue echo pattern by ultrasonography. Gray level histogram of the normal liver and the kidney were estimated with carbon tetra-chloride intoxication. In normal, r-square for liver volume to body weight was 0.93372, and this showed direct linear regression. Gray level histograms of the normal liver and the kidney were $19.150{\pm}2.490$(mean${\pm}$SD) and $13.175{\pm}2.686$(mean${\pm}$SD) respectively(p < 0.01). Liver parenchymal echogenicity was more hyperechogenic than kidney cortex echogenicity. Liver/Kidney ratio was $1.504{\pm}0.313$ and it can be used relative comparison of liver and kidney parenchymal echogenicity. In carbon-tetrachloride($CCl_4$) intoxication, changes of liver volume appeared to increase up to 24 hours after administration (p < 0.05), and decreased gradually to normal level after 2~5 days. Gray level histogram of liver parenchyma decreased up to 24hours (p < 0.01) after intoxication and then gradually increased to normal level. But that of kidney cortex had no significant change. Liver/Kidney ratio also decreased by 2 days(p < 0.01) and then gradually increased to normal level. On histopathologic features of hepatic tissues in carbon tetrachloride intoxication, both coagulative necrosis of hepatic cell and hemorrhage of centrilobular & midzonal area were identified. Conclusively, plain radiography is a useful diagnostic method for evaluating liver volume in mild hepatomegaly. Especially, it is considered that an adequate numerical processing of the liver length, depth and thoracic width and depth measurement would be helpful. Using gray level histogram, ultrasonographic evaluation was useful objective methods in early diagnosis of diffuse hepatic disease.

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성인병의 예방과 치료를 위한 영양과 운동처방 II. 고혈압과 동맥경화에 미치는 영향 (Exercise Prescription and Dietary Modification for Prevention and Treatment of Chronic Degenerative Disease II. On Arteriosclerosis and Hypertension)

  • 백영호
    • 생명과학회지
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    • 제9권2호
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    • pp.231-240
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    • 1999
  • 규칙적인 운동은 혈압을 낮춰주고 체중조절과 스트레스 해소에도 도움을 주기 때문에 협심증이나 심근경색과 같은 관상동맥질환을 예방하는데 효과가 있다. 동맥경화증을 촉진시키는 위험인자로는 고혈압, 고지혈증, 당뇨병, 비만, 지나친 흡연, 운동부족 등을 들 수 있으며, 동맥경화의 진행은 어려서부터 시작되어 연령의 증가와 어불어심해진다. 특히, 여자보다 남자에게서 더 심하다. 동맥경화증 위험인자가 있는 사람의 경우 식습관과 생활양식, 그리고 운동처방으로 동맥경화성 질환을 예방하는 것이 중요하다. 식이섬유는 체내에서 소화관의 운동을 촉진하여 장관내 체류기간을 단축시키며 콜레스테롤의 흡수를 저해하여 비만, 고지혈증, 동맥경화 및 대장암 등을 예방할 수 있다. 각종 채소류와 해조류는 불포화지방산이 다량으로 함유된 식품으로서 장내에서 콜레스테롤 흡수를 방해하는 역할을 한다. 또한 식물성 기름에 함유되어 있는 필수지방산과 불포화지방은 콜레스테롤의 대사를 촉진하는 반면 흡수를 방해하며, 과일류에는 수용성 식물섬유인 팩틴이 함유되어 있어 체내의 콜레스테롤치를 떨어뜨린다. 콜레스테롤 및 포화지방산이 적고 불포화지방산이 많은 음식을 섭취하도록 하며 식이요법만으로도 콜레스테롤치를 10~15% 감소시킬 수 있다. 운동과 식이를 병행하여 운동을 지속적으로 장기간 할 때 효과가 매우 크다. 운동은 유산소성 운동으로서 운동강도는 HRmax의 60~80$\%$ $Vo_2$ max 50~70$\%$), 운동시간은 15~60분/day, 운동빈도는 3-6회/week가 바람직하다. 특히 심한 고혈압의 경우에는 환자의 상태에 따른 운동처방의 배려가 있어야 되며, 의사와 상의하여 전문적인 처방이 필요하다. 확인되었다.H, ENO1, ADH1 promoter 순으로 나타났지만, 초기 포도당 농도가 높을 때나 에탄을 생산이 심각한 유가식 배양에서는 ENO1 promoter가 inulinase의 구성적 발현ㆍ생산에 더 적합할 것으로 사료된다.라서 체중조절을 위해서는 식이제한 보다는 자유로운 식이 섭취의 방법을 통해 더 많은 운동기간을 가지고 운동을 한다면 체중조절은 물론 근육 대사를 원활히 하여 건강한 생활을 할 수 있으리라 기대한다.공정에서 매우 효과적으로 이용될 수 있을 것으로 판단된다.게 기여하리라고 전망된다.

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