• Journal of the Optical Society of Korea
• /
• v.20 no.6
• /
• pp.653-662
• /
• 2016

An optimized multilayer superlens is designed, using a rigorous and efficient approach based on the method of moments (MoM) in conjunction with a simulated annealing (SA) algorithm. For the MoM solution, fast evaluation of closed-form Green's functions (GFs) in the spatial domain is performed by applying the complex-image (CI) technique, which obviates the time-consuming numerical evaluation of Sommerfeld integrals. The imaging capability of the superlens is examined with the correlation coefficient; results show that using circular polarization for the incident wave can improve this coefficient. To validate the proposed method, finite-element-based simulations are exploited, which reveal the method's accuracy and computational efficiency. Simulation results indicate that the designed structure is capable of producing two-dimensional sub-diffraction-limited images in the visible range, which may make it more versatile for practical applications. Finally, as a considerable finding, it is demonstrated for the proposed design that using circularly polarized illumination provides improved super-resolving performance, compared to linearly polarized illumination.

• Proceedings of the Optical Society of Korea Conference
• /
• 2008.02a
• /
• pp.429-430
• /
• 2008

We demonstrate coherent x-ray diffraction imaging using table-top x-ray laser at a wavelength of 13.9nm driven by 10-Hz ti:Sapphire laser system at the Advanced Photonics Research Institute in Korea. Since the flux of x-ray photons reaches as high as $10^9$ photons/pulse in a $20{\times}20{\mu}m^2$ field of view, we measured a ingle-pulse diffraction pattern of a micrometer-scale object with high dynamic range of diffraction intensities and successfully reconstructed to the image using phase retrieval algorithm with an oversampling ratio of 1:6. the imaging resolution is $^{\sim}150$ nm, while that is much improved by stacking the many diffraction patterns. This demonstration can be extended to the biological sample with the diffraction limited resolution.

• Korean Journal of Optics and Photonics
• /
• v.7 no.4
• /
• pp.314-321
• /
• 1996

In this paper, the chemical process of each step in fabricating the holographic phase diffraction grating with silver salt sensitive materials has been studied in detail. A new analysis of the bleaching methods have been made through the study. The result shows that among the types of bleaching methods, the reversal bleach can not be reacted chemically. And the experiments about the chemical reactions, the characteristics of the reaction products and the refractive modulation types by the bleaching methods have been done to prove the theory. It is investigated that the exposure acts as the catalyst of developing reaction and affects the developing reaction time conspicuously. At the optimum developing reaction times, which could be taken from the experiments, the holographic diffraction gratings with high diffraction efficiency over 70% could be obtained in the range of the exposure quantity 50~350 [$\mu$J/ $\textrm{cm}^2$]. From the experiments about the correlation of the chemical processing conditions of the composition of developers, the exposure, and the developing reaction time, it has proved that the enhancement of the diffraction efficiency is impossible in the limited exposure energy and conventional constant chemical reaction time.

• Molecules and Cells
• /
• v.43 no.3
• /
• pp.298-303
• /
• 2020

Cryo-electron microscopy (cryo-EM) is now the first choice to determine the high-resolution structures of huge protein complexes. Grids with two-dimensional arrays of holes covered with a carbon film are typically used in cryo-EM. Although semi-automatic plungers are available, notable trial-and-error is still required to obtain a suitable grid specimen. Herein, we introduce a new method to obtain thin ice specimens using real-time measurement of the liquid amounts in cryo-EM grids. The grids for cryo-EM strongly diffracted laser light, and the diffraction intensity of each spot was measurable in real-time. The measured diffraction patterns represented the states of the liquid in the holes due to the curvature of the liquid around them. Using the diffraction patterns, the optimal time point for freezing the grids for cryo-EM was obtained in real-time. This development will help researchers rapidly determine high-resolution protein structures using the limited resource of cryo-EM instrument access.

• Ceramist
• /
• v.10 no.3
• /
• pp.55-66
• /
• 2007

Infrared Scanning Near-field Optical Microscopy (IR-SNOM) is an extremely powerful analytical instrument since it combines IR spectroscopy's high chemical specificity with SNOM's high spatial resolution. In order to do this in the infrared, specialty chalcogenide glass fibers were fabricated and their ends tapered to generate SNOM probes. The fiber tips were installed in a modified near field microscope and both inorganic and biological samples illuminated with the tunable output from a free-electron laser located at Vanderbilt University. Both topographical and IR spectral images were simultaneously recorded with a resolution of ${\sim}50\;nm$ and ${\sim}100\;nm$, respectively. Unique spectroscopic features were identified in all samples, with spectral images exhibiting resolutions of up to ${\lambda}/60$, or at least 30 times better than the diffraction limited lens-based microscopes. We believe that IR-SNOM can provide a very powerful insight into some of the most important bio-medical research topics.

• Korean Journal of Optics and Photonics
• /
• v.5 no.2
• /
• pp.212-216
• /
• 1994

We have designed and constructed a scanner optics for thermal imaging system operating in 8 - 12 /lfll band. The scanner consists of rotating polygon and oscillating mirror for serial-parallel scan using 5 elements SPRITE HgCdTe. A spherical mirror is used for scan relay mirror to minimize size of the scan mirrors and pupil aberration. The scanner has $40^{\circ}\times26.67^{\circ}$ wide scan field of view and the calculated diffraction MTF shows diffraction limited performance. As a result we have obtained high resolution thermal image. image.

• Proceedings of the Optical Society of Korea Conference
• /
• 2003.07a
• /
• pp.66-67
• /
• 2003

고출력 반도체 레이저는 EDFA의 펌핑소스, frequency-doubling 또는 tripling을 통한 자외선 혹은 가시광선의 생성, 의료 등 많은 응용분야를 가지고 있다. 특히 테이퍼드형 반도체 레이저는 대면적 레이저 다이오드와는 달리 단일모드를 만들어내는 리지영역과 이 빔이 회절없이 전파하며 고출력을 만들어내는 이득영역으로 되어 있어 고출력의 빔을 얻을 수 있을 뿐 아니라 고출력 발진시에도 횡적 안정성을 가지는 빔을 얻을 수가 있다. (중략)

• Journal of the Optical Society of Korea
• /
• v.14 no.4
• /
• pp.424-430
• /
• 2010

In coherent anti-Stokes Raman scattering (CARS) microscopy reported until now, conventional microscope objectives are used, so that they are limited for introduction into a living body. Gradient-index (GRIN) rod lenses might be a solution for miniaturized microscope objectives for in-vivo CARS microscopy. However, due to the inherent large amount of chromatic aberration, GRIN rod lenses cannot be utilized for this purpose. CARS imaging catheter, composed of miniaturized microscope objective and fiber bundle, can be introduced into a living body for minimally invasive diagnosis. In order to design the catheter, we have to first investigate design requirements. And then, the optical design is processed with design strategies and intensive computing power to achieve the design requirements. We report the miniaturized objective lens system with diffraction-limited performance and completely corrected chromatic aberrations for an in-vivo CARS imaging catheter.

• The Journal of the Acoustical Society of Korea
• /
• v.31 no.6
• /
• pp.399-409
• /
• 2012

In this paper we propose a method for measuring the shear modulus of an ultrasound soft tissue phantom using an acoustic radiation force. The proposed method quantitatively determines the shear modulus based on the rise time of a displacement induced by an acoustic radiation force at the focal point of a focused ultrasound beam. The shear wave speed and shear modulus obtained from the proposed method and a shear wave propagation method were compared to verify the validity of the proposed method. In the shear wave propagation method, the shear modulus is first computed by measuring the propagating speed of a shear wave induced in a phantom by a limited-diffraction transmit field, and then was compared to that obtained with the proposed method in an ultrasound data acquisition system calibrated based on the first computed shear modulus. The relative errors between the two methods were found to be 4% for shear wave speed and less than 9% for shear modulus, confirming the usefulness of the proposed method.

• Journal of Advanced Navigation Technology
• /
• v.16 no.3
• /
• pp.518-525
• /
• 2012

The modulation transfer function is generally used as a method to estimate the characteristics of this kind of optical system because it cannot reappear or implement image of the object perfect. By the way, it is difficult to assess the optical system with existing MTF method since the reaction between diffraction and aberration of aperture is very complicate if the aberration is very small. The MTF has to be calculated considering the numerical aperture, defocusing, OPD and phase difference. We validate its feasibility using bessel function as an estimating method, and then realize it through illustration in this paper.