• Title/Summary/Keyword: differential evaluation

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Extraction Method of Significant Clinical Tests Based on Data Discretization and Rough Set Approximation Techniques: Application to Differential Diagnosis of Cholecystitis and Cholelithiasis Diseases (데이터 이산화와 러프 근사화 기술에 기반한 중요 임상검사항목의 추출방법: 담낭 및 담석증 질환의 감별진단에의 응용)

  • Son, Chang-Sik;Kim, Min-Soo;Seo, Suk-Tae;Cho, Yun-Kyeong;Kim, Yoon-Nyun
    • Journal of Biomedical Engineering Research
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    • v.32 no.2
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    • pp.134-143
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    • 2011
  • The selection of meaningful clinical tests and its reference values from a high-dimensional clinical data with imbalanced class distribution, one class is represented by a large number of examples while the other is represented by only a few, is an important issue for differential diagnosis between similar diseases, but difficult. For this purpose, this study introduces methods based on the concepts of both discernibility matrix and function in rough set theory (RST) with two discretization approaches, equal width and frequency discretization. Here these discretization approaches are used to define the reference values for clinical tests, and the discernibility matrix and function are used to extract a subset of significant clinical tests from the translated nominal attribute values. To show its applicability in the differential diagnosis problem, we have applied it to extract the significant clinical tests and its reference values between normal (N = 351) and abnormal group (N = 101) with either cholecystitis or cholelithiasis disease. In addition, we investigated not only the selected significant clinical tests and the variations of its reference values, but also the average predictive accuracies on four evaluation criteria, i.e., accuracy, sensitivity, specificity, and geometric mean, during l0-fold cross validation. From the experimental results, we confirmed that two discretization approaches based rough set approximation methods with relative frequency give better results than those with absolute frequency, in the evaluation criteria (i.e., average geometric mean). Thus it shows that the prediction model using relative frequency can be used effectively in classification and prediction problems of the clinical data with imbalanced class distribution.

The study on the Image Evaluation of a Preserved Tree as Growth Environment - Focused on the Zelkova serrata in Yesangun - (생육환경에 따른 보호수 이미지 평가 - 예산군 느티나무를 중심으로 -)

  • Son, Jin-Kwan;Shin, Ji-Hoon;Ann, Phil-Gyun;Kang, Bang-Hun
    • Journal of Korean Society of Rural Planning
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    • v.17 no.2
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    • pp.33-41
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    • 2011
  • To evaluate the value of a preserved tree as rural landscape resource, the growth environment and health condition was investigated, and the image evaluation was implemented on land~ape architectural major undergraduate students for zelkova trees in Yesan-gun. The image evaluation results of zelkova trees were as followings; 1) Typical image of preserved tree examined by Semantic Differential Scale were 'Old', 'Big', and 'Good'. 2) The 'big' image of zelkova tree and the height of tree, the width of tree crown, the breast girth of tree, the root girth of tree, the external formation of tree, and the health of tree bark is mutually related. Especially, the correlation between the 'big' and the external formation and the width of tree crown is high. 3) Typical image of preserved tree examined by Likert Scale were 'Natural', 'Green', 'Peaceful', and 'Rural'. 4) The preservation necessity for preserved tree was highly related with the state of ground, and the management necessity for preserved tree was highly related with contamination level and the state of ground. The appropriate management plan for preserved tree are proposed to improve the quality of rural landscape(basis of these results).

Differential Gene Expression after Adenovirus-Mediated p16 Gene Transfer in Human Non-Small Cell Lung Cancer Cells (폐암세포주에서 아데노바이러스 매개 p16 유전자 전달로 인한 유전자 발현의 변화)

  • 박미선;김옥희;박현신;지승완;엄미옥;염태경;강호일
    • Toxicological Research
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    • v.20 no.2
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    • pp.109-116
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    • 2004
  • For the safety evaluation of adenovirus-mediated gene transfer, we investigated differential gene expressions after transfecting adenoviral vector containing p16 tumor suppressor gene (Ad5CMV-p16) into human non-small cell lung cancer cells. In the previous study, we showed adenovirus-mediated $p16^{INK4a}$ gene transfer resulted in significant inhibition of cancer cell growth. We investigated gene expression changes after transfecting Ad5CMV-p16, Ad5CMV (null type, a mock vector) into A549 cells by using cDNA chip and oligonucleotide microarray chip (1200 genes) which carries genes related with signal transduction pathways, cell cycle regulations, oncogenes and tumor suppressor genes. We found that $p16^{INK4a}$ gene transfer down regulated 5 genes (cdc2, cyclin D3, cyclin B, cyclin E, cdk2) among 26 genes involved in cell cycle regulations. Compared with serum-free medium treated cells, Ad5CMV-p16 changed 27 gene expressions, two fold or more on oligonucleotide chip. In addition, Ad5CMV-p16 did not seem to increase the tumorigenicity-related gene expression in A549 cells. Further studies will be needed to investigate the effect of Ad5CMV-p16 on normal human cells and tissues for safety evaluation.

Quality Characteristics of Backsulgi with Germinated Brown Rice Flour (발아 현미를 첨가한 백설기의 품질 특성)

  • Cho, Kyung-Ryun
    • The Korean Journal of Food And Nutrition
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    • v.20 no.2
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    • pp.185-194
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    • 2007
  • This study was performed to evaluate the physicochemical, sensory evaluation of Backsulgi changed with germinated brown rice flour(GBRF) at different ratio. Moisture content decreased gently during storage and the decrease was less in GBRF-added groups than the control group. The color L value decreased significantly by with increasing the GBRF, wherease the redness(a) and yellowness(b) were both increased. As the result of measurement with texture analyzer, hardness, gumminess, chewiness, adhesiveness and fracturability of Backsulgi tended to decrease in proportion to the amount of GBRF in the formula. The thermal properties of Backsulgi were investigated by differential scanning calorimetry(DSC). Onset temperature and peak temperature of gelatinizatino in thermal characteristics showed low in case of addition of GBRF into Backsulgi. All samples changed with GBRF had low values in change of melting enthalphy. In the sensory evaluation, Backsulgi with GBRF were superior in flavor, cohesiveness, hardness, chewiness and moistureness than that of control. And Backsulgi with 20% GBRF showed the highest score in overall acceptability. Therefore we concluded that the addition of GBRF on Backsulgi improve the sensory characteristics as well as delay the retrogradation.

The Effect of Motives of Ramie Fabrics on Sensory Image Evaluation (모시 소재의 문양에 따른 감성 이미지 평가)

  • Lee, Soon-Im;Kim, Jae-Sook
    • The Research Journal of the Costume Culture
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    • v.14 no.6
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    • pp.1015-1026
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    • 2006
  • The purpose of the study were to find out (1) the effect of motives on perceiver's image perception on ramie fabrics, and perceiver's trait, age and gender on sensory image evaluation of ramie fabrics. The research was a quasi experiment and experimental materials developed for the study were a set of material stimuli and semantic differential scales to measure sensory image of the stimuli, an aesthetic value scale. the independent design was motif design techniques(Plain Weave, burnt-out, embroidery, stripe, check). The subjects were 421 adults in Daejeon and Seachun. The results was as follows: The factor analysis of semantic differential scales for the ramie materials emerged 4 different image dimensions: attractiveness, hand, elegance, weight). The five design techniques showed significantly different image affects on some selective dimensions. The burn-out design gave the most attractive image, the embroidery design gave the softest image and plain weaved fabric presented the lightest hand image. Consumer's aesthetic values, gender and age tended to affect sensory image evaluation of ramie materials. On conclusion the result revealed that design strategy for the ramie material, design development though motives will be an essential process. and for material design pursued design image and target consumer's trait should be carefully considered.

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Accuracy evaluation of 3D time-domain Green function in infinite depth

  • Zhang, Teng;Zhou, Bo;Li, Zhiqing;Han, Xiaoshuang;Gho, Wie Min
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.13 no.1
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    • pp.50-56
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    • 2021
  • An accurate evaluation of three-dimensional (3D) Time-Domain Green Function (TDGF) in infinite water depth is essential for ship's hydrodynamic analysis. Various numerical algorithms based on the TDGF properties are considered, including the ascending series expansion at small time parameter, the asymptotic expansion at large time parameter and the Taylor series expansion combines with ordinary differential equation for the time domain analysis. An efficient method (referred as "Present Method") for a better accuracy evaluation of TDGF has been proposed. The numerical results generated from precise integration method and analytical solution of Shan et al. (2019) revealed that the "Present method" provides a better solution in the computational domain. The comparison of the heave hydrodynamic coefficients in solving the radiation problem of a hemisphere at zero speed between the "Present method" and the analytical solutions proposed by Hulme (1982) showed that the difference of result is small, less than 3%.

Development of Differential Exhaust Flow Controller using One Chip Microcontroller (단일칩 마이크로컨트롤러를 이용한 차압식 유량제어기의 개발)

  • Park, Chan-Won;Kim, Hyun-Sik;Joo, Yong-Kyu
    • Journal of Industrial Technology
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    • v.22 no.A
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    • pp.89-94
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    • 2002
  • In this paper, a Exhaust Flow Controller (EFC) technology for uniform application of film coater and developer device is introduced that spread and remove photo resister at semiconductor manufacturing process. Because developed EFC device uses differential pressure sensing method as a differential flow meter and embodied smart A/D conversion by using a one chip microprocessor and devised by feedback Servo control, It has shown excellent performance and stability evaluation, as maximum 2000L/min flow, capability of installation to actual semiconductor equipment.

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Analysis of Thrust/Torque Signature of MOV (원자력 발전소 모터구동밸브의 쓰러스트/토크 신호 분석)

  • Ryu, Ho-Geun;Park, Seong-Keun;Kim, Dae-Woong
    • Proceedings of the KSME Conference
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    • 2001.06e
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    • pp.613-618
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    • 2001
  • For the evaluation of operability of MOV(Motor Operated Valve), the precision prediction of thrust/torque acting on the valve is important. In this paper, the analytical prediction method of thrust/torque was proposed. The design basis stem thrust calculation typically considers the followings: Packing thrust, Stem rejection load, design basis differential pressure load. In general, test results show that temperature, pressure, fluid type, and differential pressure, independently and combination, all have an effect on the friction factor. The prediction results of thrust/torque are well agrement with dynamic test results.

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A Study on Evaluation of the Korean and Western Dresses Using Semantic Differential Scales (의미분별척도법 (Semantic Differential)에 의한 양장과 한복의 이미지 비교 평가)

  • Hong Byung Sook
    • Journal of the Korean Society of Clothing and Textiles
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    • v.12 no.3 s.28
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    • pp.373-382
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    • 1988
  • The purpose of this study is to compare the image discrepancy with Korean clothing and Western clothing using semantic differential scales. 19 adjective pairs were used for this study. The survey questionnaire were given to 946 married - women in Seoul. For the statistical analysis frequency, percentage, mean, ANOVA, t-test and Factor analysis were used. T he major findings were as follows: 1. To evaluate the women's clothing, four major factors were obtained and it was found that women evaluated quite differently their dresses with Korean and western styles. 2. The major evaluating factor of Korean dress was aesthetic aspect and on the other hand the main factor of western dress was functional aspect.

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Practical Security Evaluation against Differential and Linear Cryptanalyses for the Lai-Massey Scheme with an SPS F-function

  • Fu, Lishi;Jin, Chenhui
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.10
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    • pp.3624-3637
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    • 2014
  • At SAC 2004, Junod and Vaudenay designed the FOX family based on the Lai-Massey scheme. They noted that it was impossible to find any useful differential characteristic or linear trail after 8 rounds of FOX64 or FOX128. In this paper, we provide the lower bound of differentially active S-boxes in consecutive rounds of the Lai-Massey scheme that has SPS as its F-function, and we propose the necessary conditions for the reachability of the lower bound. We demonstrate that similar results can be obtained with respect to the lower bound of linearly active S-boxes by proving the duality in the Lai-Massey scheme. Finally, we apply these results to FOX64 and FOX128 and prove that it is impossible to find any useful differential characteristics or linear trail after 6 rounds of FOX64. We provide a more precise security bound for FOX128.