• Imaging Science in Dentistry
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• v.50 no.4
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• pp.273-279
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• 2020

This review presents an overview of some diagnostic imaging-related issues regarding medication-related osteonecrosis of the jaws(MRONJ), including imaging signs that can predict MRONJ in patients taking antiresorptive drugs, the early imaging features of MRONJ, the relationship between the presence or absence of bone exposure and imaging features, and differences in imaging features by stage, between advanced MRONJ and conventional osteomyelitis, between oncologic and osteoporotic patients with MRONJ, and depending on the type of medication, method of administration, and duration of medication. The early diagnosis of MRONJ can be made by the presence of subtle imaging changes such as thickening of the lamina dura or cortical bone, not by the presence of bone exposure. Most of the imaging features are relatively non-specific, and each patient's clinical findings and history should be referenced. Oral and maxillofacial radiologists and dentists should closely monitor plain radiographs of patients taking antiresorptive/antiangiogenic drugs.

• International Journal of Advanced Culture Technology
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• v.10 no.3
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• pp.281-286
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• 2022

In this study, design of an intuitive internal resistance diagnostic device is to diagnose the residual capacity and aging of the battery regardless of the model and the internal protocol of the waste battery through the method of measuring the internal resistance of a waste battery. In this paper, charging and discharging were continuously performed with 2A charging and 5A discharging in order to secure data on impedance changes that may occur in the charging and discharging process of various methods. As a result of the final experiment, it was confirmed that the impedance change occurred during charging and discharging, and the amount of change increased as the charging/discharging C-rate increased. In addition, it was confirmed that the waste battery aged or abnormal cell had a large change in the impedance value.

• Journal of Genetic Medicine
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• v.20 no.2
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• pp.46-51
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• 2023

Exonic copy number variation (CNV), involving deletions and duplications at the gene's exon level, presents challenges in detection due to their variable impact on gene function. The study delves into the complexities of identifying large CNVs and investigates less familiar but recurrent exonic CNVs, notably enriched in East Asian populations. Examining specific cases like DRC1, STX16, LAMA2, and CFTR highlights the clinical implications and prevalence of exonic CNVs in diverse populations. The review addresses diagnostic challenges, particularly for single exon alterations, advocating for a strategic, multi-method approach. Diagnostic methods, including multiplex ligation-dependent probe amplification, droplet digital PCR, and CNV screening using next-generation sequencing data, are discussed, with whole genome sequencing emerging as a powerful tool. The study underscores the crucial role of ethnic considerations in understanding specific CNV prevalence and ongoing efforts to unravel subtle variations. The ultimate goal is to advance rare disease diagnosis and treatment through ethnically-specific therapeutic interventions.

• Korean Journal of Radiology
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• v.24 no.9
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• pp.871-889
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• 2023

C-X-C motif chemokine receptor 4 (CXCR4) plays a key role in various physiological functions, such as immune processes and disease development, and can influence angiogenesis, proliferation, and distant metastasis in tumors. Recently, several radioligands, including peptides, small molecules, and nanoclusters, have been developed to target CXCR4 for diagnostic purposes, thereby providing new diagnostic strategies based on CXCR4. Herein, we focus on the recent research progress of CXCR4-targeting radioligands for tumor diagnosis. We discuss their application in the diagnosis of hematological tumors, such as lymphomas, multiple myelomas, chronic lymphocytic leukemias, and myeloproliferative tumors, as well as nonhematological tumors, including tumors of the esophagus, breast, and central nervous system. Additionally, we explored the theranostic applications of CXCR4-targeting radioligands in tumors. Targeting CXCR4 using nuclear medicine shows promise as a method for tumor diagnosis, and further research is warranted to enhance its clinical applicability.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1050-1055
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• 2011

This paper presents a novel diagnostic method to determine Sasang Consitution (SC) by elasticity coefficient of hand dorsal skin of elderly people. For this purpose, we carried out a clinical test, in which Our SC diagnostic tool and one Oriental medical doctor with SC medicine expertise participated to categorize 458 healthy subjects into four constitutions. After excluding heavy-noise, we extracted 295 subjects' elasticity coefficient feature data and statistically analyzed their SC relevance with ANOVA test. It resulted in that, Taeum-in has high elasticity coefficient compared to Soeum-in in a significance level of 0.05. There are no differences of elasticity coefficient in genders. This result is supported by the theory of Longevity and Life Preservation in Eastern Medicine(Donguisusebowon, 동의수세보원) which suggested that Taeum-in's flesh is solid and Soeum-in's one is tender. This is the first work which reports the relatedness of skin elasticity coefficient and SC by an objective clinical test.

• Journal of Korea Society of Industrial Information Systems
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• v.21 no.6
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• pp.13-21
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• 2016

Feature selection is the one of important issue in the field of data mining and machine learning. It is the technique to find a subset of features which provides the best classification performance, from the source data. We propose a feature subset selection method using the neighborhood rough set model based on information granularity. To demonstrate the effectiveness of proposed method, it was applied to select the useful features associated with breast tumor diagnosis of 298 shape features extracted from 5,252 breast ultrasound images, which include 2,745 benign and 2,507 malignant cases. Experimental results showed that 19 diagnostic features were strong predictors of breast cancer diagnosis and then average classification accuracy was 97.6%.

• The Korean Journal of Applied Statistics
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• v.20 no.2
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• pp.229-244
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• 2007

Among the small area estimation methods, it has been known that hierarchical Bayesian(HB) approach is the most reasonable and effective method. However any model based approaches need good explanatory variables and finding them is the key role in the model based approach. As the lacking of explanatory variables, adopting the spatial terms in the model was introduced. Here in this paper, we evaluate the model based methods with/without spatial terms using the diagnostic methods which were introduced by Brown et al. (2001). And Economic Active Population Survey(2005) is used for data analysis.

• Journal of Electrical Engineering and Technology
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• v.11 no.1
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• pp.29-37
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• 2016

Fast and accurate fault diagnosis of the position sensor is of great significance to ensure the reliability as well as sensor fault tolerant operation of the Switched Reluctance Wind Generator (SRWG). This paper presents a fault diagnostic scheme for a SRWG based on the residual between the estimated rotor position and the actual output of the position sensor. Extreme Learning Machine (ELM), which could build a nonlinear mapping among flux linkage, current and rotor position, is utilized to design an assembled estimator for the rotor position detection. The data for building the ELM based assembled position estimator is derived from the magnetization curves which are obtained from Finite Element Analysis (FEA) of an SRWG with the structure of 8 stator poles and 6 rotor poles. The effectiveness and accuracy of the proposed fault diagnosis method are verified by simulation at various operating conditions. The results provide a feasible theoretical and technical basis for the effective condition monitoring and predictive maintenance of SRWG.

• Journal of radiological science and technology
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• v.22 no.2
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• pp.23-26
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• 1999

The Zygomatic arch is structurally protruded and is easily fractured. The classic management of zygomatic arch fracture has been mentioned the Keen, Lothrop, Dingman and Ailing and threaded K-wire. All of the above methods have advantages and disadvantages. To minimize the disadvantages, we performed threaded K-wire for the first time using C-arm image intensifier. The subjects were 16 patients with Knight North group II (Zygomatic arch fracture). Among them the C-arm was used in 12 patients and the operator used sensitivity general method in 4 patients and confirmed the operation by mobile X-ray equipment. In conclusion, both groups were satisfied surgically and cosmetically. Using the C-arm, actual image at the time operation was clear and satisfied, the surrounding tissue damage was minimized and at was more accurately completed. The operation time was shortened by 30 to 60 minutes proving it to be an efficient method. We suggest though that further studies be needed to evaluate the radiation effect on these patients.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.244-247
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• 2002

We examined a possibility to use inorganic plastic scintillator, which has the effective atomic number close to that of human soft tissue, for the measurement of dose distributions in a shorter time period. The method was to irradiate a block of plastic scintillator as a phantom, and to measure the distribution of the scintillation light by a wave length analyzer through a thread of plastic optical fiber. By irradiating the diagnostic x-ray, we observed the emission spectrum of the scintillation light from the scintillator. It showed a peak at around 420nm with a full width of 140 nm. The emission spectrum was integrated to determine the total number of photons. The dependences of the amount of photons on the irradiated dose were measured. The results of the experiment show that the amount of emission light is in proportional to the irradiated dose. From this fact, we conclude that the present method can be used for the measurement of the depth dose distribution of the diagnostic x-rays.