• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.218-228
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• 2021

Due to their high degree of freedom to transfer and acquire light, fiber optics can be used in the presence of strong magnetic fields. Hence, optical sensing and imaging based on fiber optics can be integrated with magnetic resonance imaging (MRI) diagnostic systems to acquire valuable information on biological tissues and organs based on a magnetic field. In this article, we explored the combination of MRI and optical sensing/imaging techniques by classifying them into the following topics: 1) functional near-infrared spectroscopy with functional MRI for brain studies and brain disease diagnoses, 2) integration of fiber-optic molecular imaging and optogenetic stimulation with MRI, and 3) optical therapeutic applications with an MRI guidance system. Through these investigations, we believe that a combination of MRI and optical sensing/imaging techniques can be employed as both research methods for multidisciplinary studies and clinical diagnostic/therapeutic devices.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 춘계학술대회
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• pp.55-57
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• 1992

Image display is the last step of imaging chain in which the diagnostic information is transformed into perceivable intensities and transformed to observer's eye-brain system. In this process, a certain part of information may be efficiently transfered and another part may be inefficiently transfered leading to information loss. In this study, the visual perceptual properties of image display on CRT monitor has been investigated. Psychophysical experiment of target image detection has been performed using CRT monitor for various background grey levels, and the threshold difference grey levels required for visual discrimination have been predicted by computer simulation with visual model.

• 대한의용생체공학회:의공학회지
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• 제15권1호
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• pp.63-70
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• 1994

A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors'reporting results. Input int'ormation was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and Analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed id'ormation can be transferred for patient diagnosis through LAN (local area network).

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.322-323
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• 2002

Partial volume averaging effect of PET data influences on the accuracy of quantitative measurements of regional brain metabolism because spatial resolution of PET is limited. The purpose of this study was to evaluate the accuracy of partial volume correction carried out on $^{18}$ F-PET images using Hoffman brain phantom. $^{18}$ F-PET Hoffman phantom images were co-registered to MR slices of the same phantom. All the MR slices of the phantom were then segmented to be binary images. Each of these binary images was convolved in 2 dimensions with the spatial resolution of the PET. The original PET images were then divided by the smoothed binary images in slice-by-slice, voxel-by-voxel basis resulting in larger PET image volume in size. This enlarged partial volume corrected PET image volume was multiplied by original binary image volume to exclude extracortical region. The evaluation of partial volume corrected PET image volume was performed by region of interests (ROI) analysis applying ROIs, which were drawn on cortical regions of the original MR image slices, to corrected and original PET image volume. From the ROI analysis, range of regional mean values increases of partial volume corrected PET images was 4 to 14%, and average increase for all the ROIs was about 10% in this phantom study. Hoffman brain phantom study was useful for the objective evaluation of the partial volume correction method. This MR-based correction method would be applicable to patients in the. quantitative analysis of FDG-PET studies.

• 전자공학회논문지CI
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• 제44권3호
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• pp.43-48
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• 2007

초고속 인터넷의 발달과 휴대용 임베디드시스템이 보편화된 유비쿼터스 환경 아래에서 의료영상처리 분야에도 언제 어디서든지 원하는 환자에 대한 정보를 검색하고 판독할 수 있는 시스템에 대한 연구 및 개발이 활발하게 이루어지고 있다. 특히, scout 영상은 진단 목적 이외에 새로운 응용분야에서 필요로 하고 있다. 유비쿼터스 시스템 개발로 의료 영상 뷰어는 PACS 시스템 및 웹브라우저와 결합한 병원에서 활용되고 있다. 본 논문은 무선 환경에서 잠재력을 보여주고 있는 이동단말기 기반의 의료영상 뷰잉시스템을 구현하였다.

• 대한의용생체공학회:의공학회지
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• 제8권2호
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• pp.189-198
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• 1987

Digital Subtraction Angiography(DSA) technique has been widely used to detect vascular diseases and hemodynamic parameters noninvasively. However, there factors in fluencing the resultant DSA image quality. In this paper, several important factors are suggested to improve the DSA image quality based on mathematicical analysis. Experimental DSA images for different filters are shown and also dicussed the difference between original and processed image qualities.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 ITC-CSCC -1
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• pp.39-42
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• 2000

In our study, by observing and analyzing normal liver in abdominal CT image, we estimated gray value range and generated binary image. In the binary image, we achieved the number of hole which is located between pixels. Depending on the ratio, we processed the input image to 4 kinds of mesh images to remove the noise part that has the different ratio. With the Union image of 4 kinds of mesh images, we generated the template representing general outline of liver and subtracted from the binary image so the we can represent the organ boundary to be minute. With results of proposed method, processing time is reduced compared with existing method and we compared the result image to manual image of medical specialists.

• 대한의용생체공학회:의공학회지
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• 제8권2호
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• pp.255-270
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• 1987

A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network).

• 대한방사선기술학회지:방사선기술과학
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• 제22권1호
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• pp.49-53
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• 1999

To inquire its usefulness of the clinical application of intelligent replenishment system of automatic X-ray film processor based on film density, we processed the serial 300 sheets of radiographic film of chest [$14{\times}14"$, HR-C type] and bone [elbow & ankle($8{\times}10"$), skull($10{\times}12"$), hand & foot($11{\times}14"$), pelvis($14{\times}17"$), HR-G type, 68, 70, 77, 85 sheets respectively]. We analyzed the characteristic corves, relative speeds, average gradients and base plus fog densities every twenty five sheets. We also evaluated the developer and fixer replenishment volumes every that time. In the chest and bone radiograph two all, the characteristic curves were little change, and the relative speeds, average gradients and base plus fog densities were within the maximum control limits. The average developer replenishment volumes were about 43m1/sheet and 39m1/sheet respectively. It brings decreased results about 29% in comparison with the conventional replenishment system. In our experiences, we conclude that the intelligent replenishment system of automatic X-ray film processor based on film density maintains image quality consistently, decreases also the replenishment volumes. Therefore, this system will be resulted in economic and environmental effects, and solve problems of over and low replenishment volume.

• Korean Journal of Radiology
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• 제2권1호
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• pp.21-27
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• 2001

Objective: To identify and evaluate the lateral border zone by comparing the size and distribution of the abnormal signal area demonstrated by MR imaging with the infarct area revealed by pathological examination in a reperfused myocardial infarction cat model. Materials and Methods: In eight cats, the left anterior descending coronary artery was occluded for 90 minutes, and this was followed by 90 minutes of reperfusion. ECG-triggered breath-hold turbo spin-echo T2-weighted MR images were initially obtained along the short axis of the heart before the administration of contrast media. After the injection of Gadomer-17 and Gadophrin-2, contrast-enhanced T1-weighted MR images were obtained for three hours. The size of the abnormal signal area seen on each image was compared with that of the infarct area after TTC staining. To assess ultrastructural changes in the myocardium at the infarct area, lateral border zone and normal myocardium, electron microscopic examination was performed. Results: The high signal area seen on T2-weighted images and the enhanced area seen on Gadomer-17-enhanced T1WI were larger than the enhanced area on Gadophrin-2-enhanced T1WI and the infarct area revealed by TTC staining; the difference was expressed as a percentage of the size of the total left ventricle mass (T2= 39.2 %; Gadomer-17 =37.25 % vs Gadophrin-2 = 29.6 %; TTC staining = 28.2 %; p < 0.05). The ultrastructural changes seen at the lateral border zone were compatible with reversible myocardial damage. Conclusion: In a reperfused myocardial infarction cat model, the presence and size of the lateral border zone can be determined by means of Gadomer-17- and Gadophrin-2-enhanced MR imaging.