• 대한한의진단학회지
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• 제17권2호
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• pp.77-89
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• 2013

Objectives Tongue diagnosis is an important diagnostic method in traditional Eastern medicine, and it has a high potential to be used in the future healthcare because of easy, quick, and non-contact measuring features. Recently, research and development efforts on computerized tongue diagnosis systems (CTDS) have been active that led to the technical advancements in the field of photographing techniques, image extraction and classification algorithms. In this study, we analyzed the trends in the CTDS patents. Using the WIPS search engine (www.wipsglobal.com), quantitative and qualitative patent analyses were performed through Korea, China, Japan, U.S.A and Europe. Methods For a systematic search and data analysis, we defined patent categories based on the application area and technical details. By applying thus-obtained categorical key words, we obtained 360 relevant patents on photographing techniques, image extraction and classification algorithms for the purpose of diagnosis or security. Results As a result, companies related to image acquisition, medical imaging and mobile devices and research groups of universities in East Asia were major patent applicants. In all the five countries, the number of patents have been increasing since 1980. In particular, technology related to color correction and image segmentation were most actively patented categories, and expected to continue a high application rate.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제44권2호
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• pp.66-72
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• 2018

Objectives: Desmoplastic melanoma of the oral cavity is an extremely rare condition that is often confused on initial diagnosis with non-melanotic benign lesion or spindle cell tumors. The purpose of this article was to raise awareness of the disease using a literature review. Materials and Methods: We analyzed 19 desmoplastic melanoma cases reported in the literature and added our experience. Data on clinical, histopathology, treatment, and survival were retrieved and analyzed. Survival analysis was by the Kaplan-Meier method. Results: Initial clinical and histopathological features were indistinctive, and a definite diagnosis of desmoplastic melanoma at initial assessment was possible in only 23.5% of cases. Among tests, immunohistochemical studies for S-100 and vimentin were all positive. The 5-year disease-free survival rate for oral desmoplastic melanoma was 0%, and the 5-year overall survival rate was 55.0%. Conclusion: Oral desmoplastic melanoma has a high percentage of initial misdiagnosis and propensity for local recurrence. Thus, careful initial diagnosis and adequate surgery may result in improved overall survival.

• Advances in pediatric surgery
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• 제7권1호
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• pp.54-58
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• 2001

Slide tracheoplasty. as a treatment for congenital tracheal stenosis, has been recently reported to have good results and quite a number of advantages as compared with conventional tracheoplasties. The aim of this study is to report a new surgical technique modified from the slide tracheoplasty. "the slide cricotracheoplasty" for the congenital cricotracheal stenosis. A girl was born by Cesarean section and the diagnosis of esophageal atresia (Gross type C) and cricotracheal stenosis (30 % of total length of trachea) was established. Esophageal atresia was successfully corrected at the 8th day of life. At the 31st day of life, corrective surgery for congenital cricotracheal stenosis. the slide cricotracheoplasty. was performed with success. Slide cricotracheoplasty is almost the same procedure as slide tracheoplasty except for two technical features. First the cricoid cartilage was split on its anterior surface. Second the split cricoid cartilage was fixed to pre vertebral fascia to maintain enough space to accommodate the sliding caudal segment of trachea because of the stiffness of the cricoid cartilage. We believe that the sliding cricotracheoplasty is a new surgical technique for congenital cricotracheal stenosis that has similar results and advantages as the sliding tracheoplasty.

• 한국학교수학회논문집
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• 제18권2호
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• pp.223-240
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• 2015

본 논문의 목적은 미적분에 관한 보충학습을 요하는 이공계 대학생들을 위하여 공업수학의 벡터미적분 교육을 중심으로 개념적 이해와 계산 과정의 단계별 풀이를 보여주는 웹 기반 이러닝 콘텐츠를 설계 및 개발하는 것이다. 이를 위하여 먼저 수학교육용 소프트웨어에 관한 고찰을 하였으며 학교 수학에서 등장하는 문제해결의 과정을 규칙 재작성으로 처리함으로써 화이트박스 형태의 콘텐츠 제작에 관한 이론적 토대를 살펴보았다. 구체적으로 Mathematica의 패턴 매칭을 이용하여 미분과 적분 연산자를 구현하였고, 이를 벡터미적분에서 등장하는 매개변수화된 곡선에 대한 길이 구하기 문제에 적용함으로써 콘텐츠 개발의 예를 제시하였다. 튜토리얼 형태로 개발된 이러닝 콘텐츠는 단계별 풀이 과정이 나오는 실습하기 콘텐츠와 퀴즈 문제를 통하여 학습자의 과정을 진단해 주는 형성평가 모듈로 구성되었다. 끝으로 개발된 이러닝 콘텐츠의 특징과 이공계 대학생들의 수학에 관한 기초학력을 증진하는데 활용될 수 있는 장점을 살펴보았으며 향후 연구 방향을 제시하였다.

• 한국콘텐츠학회논문지
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• 제10권2호
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• pp.258-267
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• 2010

방사선피폭에 대한 관심이 높아지면서 X선 검사시에 환자에게 조사되는 피폭선량을 정확히 알고 있다는 것은 환자의 불안을 해소하고 또 방사선사나 의사가 피폭선량 경감의식을 향상시키는 데 중요하지만, 임상에서 측정기를 보유하고 있는 시설은 극소수에 불과하다. 본 연구에서는 bit system 및 NDD-M법의 특징을 살려서 우리나라에 사용되고 있는 진단용 X선장치의 출력선량을 직접 측정하여 도표화 하고, X선 출력선량을 아는 경우 또는 모르는 경우 모두에서 적절히 적용할 수 있게 두 가지 방법을 제시하여 실측선량과 비교 실험을 하였다. 그 결과 bit system 및 NDD-M법보다 정확도가 우수한 결과를 나타내어 임상에서 환자가 받는 선량을 더욱 쉽게 알 수 있게 됨으로 방사선관련 종사자들의 의료피폭에 대한 관심이 더욱 높아지고 의료선량감소에 한층 더 노력하는 계기가 될 것으로 사료된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제7권1호
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• pp.87-91
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• 2004

저자들은 복통과 구토에 동반된 전신 부종을 주소로 내원하여 저알부민혈증과 말초혈액 호산구증가증의 임상 소견으로 단백 소실성 위장증을 동반한 호산구성 위장관염으로 의심되었으나, 내시경검사 소견, 조직 소견, 방사선 소견과 저절로 좋아지는 일과성 임상 경과 등을 종합하여 말초혈액의 호산구 증가증과 조직 내에서 호산구의 심한 침윤을 보인 CMV 감염 소아 Menetrier병 1례를 보고하고자 한다. CMV 감염과 관련된 소아 Menetrier병의 특징적인 임상 증상과 소견을 염두에 두어야 하며, 향후 CMV 감염과 말초 혈액 호산구증가증과 조직내 호산구 침윤의 관련성에 대하여 임상적 해석이 필요하리라 판단된다.

• Pediatric Infection and Vaccine
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• 제22권1호
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• pp.40-44
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• 2015

비정형 가와사키병은 가와사키병의 진단기준을 충족하지 않는 경우를 말하며, 주로 6개월 미만의 영아에게서 발현하는 경우가 많다. 비정형 가와사키병의 임상소견은 뇌수막염과 같은 감염질환과 비슷할 때가 있어서, 이러한 경우 임상적으로 비정형 가와사키병을 감염질환과 감별하기 어려울 때가 많다. 또한 가와사키병과 연관되어 보고된 신경계 이상은 무균수막염, 경막하삼출, 안면신경마비, 뇌경색증, 뇌병증, 뇌자기공명영상의 가역적 뇌량팽대 변화 등이 있다. 본 저자들은 뇌척수액세포증가증과 경막외삼출액이 동반된 비정형 가와사키병으로 진단된 5개월 여아에 대해 보고하는 바이다. 환자의 심장초음파검사에서 관상동맥이 늘어나 있었고, 추적관찰에서 경막외 삼출액과 관상동맥 합병증이 모두 회복되었으며 생후 12개월에 발달이정표는 정상이었다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6337-6340
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• 2013

Through retrospective analysis of 13 cases of magnetic resonance image (MRI) manifestations of atypical meningiomas confirmed by operation and pathology in the First Affiliated Hospital of Xinxiang Medical University, the objective of this study was to evaluate the diagnostic value of MRI in order to improve the accuracy rate of preoperative diagnosis. In this retrospective analysis of MRI findings for atypical meningiomas in First Affiliated Hospital of Xinxiang Medical University from January to July in 2012, the location, morphology and tumor signals and other tumor imaging characteristics were covered. In 13 cases of atypical meningioma patients of this group, most tumors were located at typical sites (10/13), mainly the falx cerebri, parasagittal, convexity, saddle area. Only two cases were at atypical locations, 1 in the cerebellar hemisphere and 1 in a lateral ventricle. Most of the tumors showed T1 and T2 isointensity signals, and necrosis, calcification, and peritumoral edema were always featured. DWI showed isointensity in 11 cases (11/13), and hyperintensity in 2. Some 9 cases had dural tail signs, 12 had accurate positioning (12/13), and 2 were postoperative recurrences. MRI has high value in the diagnosis of atypical meningiomas, with important roles in early clinical diagnosis, treatment and prognosis evaluation.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제6권2호
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• pp.202-207
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• 2003

장신경 이형성증은 만성 가성 폐색 증후군의 드문 원인질환으로 임상 증상이 선천성 거대결장증과 유사하여 진단이 늦어지는 경우가 많기 때문에 임상적인 의심이 필요하다. 저자들은 쌍생아에서 신생아기에 태변이 배출되지 않고 복부 팽만을 보여 선천성 거대결장증이 의심되었으나 임상경과와 조직검사로 진단된 장신경 이형성증을 보고하는 바이다.

• 한국임상수의학회지
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• 제35권4호
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• pp.155-160
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• 2018

A 6-year-old intact female Shih-tzu dog was referred due to anorexia. Physical examination, complete blood count, serum chemical analysis, radiography, and ultrasonography were evaluated. Physical examination and hematological analysis showed normal findings. Abdominal radiographs and ultrasound revealed well-defined masses in the spleen. Other abdominal organs showed no significant abnormalities. Tissue samples taken via sono-guided fine needle aspiration of the splenic mass showed many bare nuclei, which were variable in size. Results of histopathological and immunohistochemical (IHC) analyses performed after splenectomy were consistent with paraganglioma. Based on these findings, we diagnosed this patient with a paraganglioma of splenic origin. Two months after splenectomy, abdominal ultrasonography revealed a new neoplastic lesion in the liver. The clients refused further management and the patient expired three months after initial diagnosis. Necropsy as well as histopathological and IHC examinations of other systemic organs including the liver, adrenal gland, kidney, brain, urinary bladder, lung, aortic body, carotid body, and pancreas were performed. The neoplastic tissue in the liver also demonstrated features of a paraganglioma, and there were no remarkable findings in all other organs.