• Title/Summary/Keyword: diagnostic approach

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Transaxillary Approach for First Rib Resection to Relieve Thoracic Outlet Syndrome - A Case Report - (액와접근법을 통한 제 1 늑골 절제술로 치료한 흉곽출구 증후군 - 증례보고 -)

  • Kwon, Ki Young;Jeon, Byung Chan;Cho, Yong Woon;Cho, Sung Rae
    • Journal of Korean Neurosurgical Society
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    • v.30 no.12
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    • pp.1443-1448
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    • 2001
  • The authors report a case of thoracic outlet syndrome in left side. Thoracic outlet syndrome is a collective term in which symptoms and signs are due to bony and soft tissue compression of the neurovascular bundle at the thoracic outlet. It is a rare case in neurosurgical field. So we had experienced one case of thoracic outlet syndrome which was improved by transaxillary approach for resection of first rib. The clinical features, diagnostic test, radiological findings, and operative technique are presented with review of literatures.

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A Statistical Approach to Analysis of Saccadic Eye Movements (Saccadic 안구운동 해석에 대한 통계학적인 접근)

  • Kim, Nam-Gyun;Kim, Bu-Gil
    • Journal of Biomedical Engineering Research
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    • v.10 no.3
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    • pp.289-292
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    • 1989
  • In this study we propose an approach based on statistical method which use the whole of saccades instead of using a few points of saccades in the quantitative analyse saccades. We computed statistical parameters such as mean velocity, quadratic mean velocity, standard duration, skewness of saccades velocity, flattness factor of saccades velocity, and mean delay by considering eye velocity as a probability density function. The results abtained are the following as ; This parameters showed the same trend like that of the main sequence. They were not biased by the systematic errors due to the arbitrary threshold. They were also less sensitive to noise, which was tested through the model simulation. So they are expected to provide a more comprehensive quantitative description of the dynamic properties of saccade in the diagnostic field.

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Synthetic approach to the generation of antibody diversity

  • Shim, Hyunbo
    • BMB Reports
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    • v.48 no.9
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    • pp.489-494
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    • 2015
  • The in vitro antibody discovery technologies revolutionized the generation of target-specific antibodies that traditionally relied on the humoral response of immunized animals. An antibody library, a large collection of diverse, pre-constructed antibodies, can be rapidly screened using in vitro display technologies such as phage display. One of the keys to successful in vitro antibody discovery is the quality of the library diversity. Antibody diversity can be obtained either from natural B-cell sources or by the synthetic methods that combinatorially generate random nucleotide sequences. While the functionality of a natural antibody library depends largely upon the library size, various other factors can affect the quality of a synthetic antibody library, making the design and construction of synthetic antibody libraries complicated and challenging. In this review, we present various library designs and diversification methods for synthetic antibody library. From simple degenerate oligonucleotide synthesis to trinucleotide synthesis to physicochemically optimized library design, the synthetic approach is evolving beyond the simple emulation of natural antibodies, into a highly sophisticated method that is capable of producing high quality antibodies suitable for therapeutic, diagnostic, and other demanding applications. [BMB Reports 2015; 48(9): 489-494]

A Concept of Self-Optimizing Forming System (자율 최적 성형 공정 시스템 개발)

  • Park, Hong-Seok;Hoang, Van-Vinh;Song, Jun-Yeob;Kim, Dong-Hoon;Le, Ngoc-Tran
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.2
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    • pp.292-297
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    • 2013
  • Nowadays, a strategy of the self-optimizing machining process is an imperative approach to improve the product quality and increase productivity of manufacturing systems. This paper presents a concept of self-optimizing forming system that allows the forming system automatically to adjust the forming parameters online for guarantee the product quality and avoiding the machine stop. An intelligent monitoring system that has the functions of observation, evaluation and diagnostic is developed to evaluate the pully quality during forming process. Any abnormal variation of forming machining parameters could be detected and adjusted by an intelligent control system aiming to maintain the machining stability and the desired product quality. This approach is being practiced on the pully forming machine for evaluating the efficiency of the proposed strategy.

Differential Diagnosis of Chronic Coughing (만성 기침의 감별진단)

  • Do, Nam Yong;Park, Jun-Hee
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.27 no.2
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    • pp.87-90
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    • 2016
  • Cough, the most common symptom, encountered in the outpatient clinic can be caused by various underlying diseases. It defines as chronic cough that the duration of cough is more than 8 weeks with a normal chest X-ray findings. The cause of cough can be found out for more than 90% through the appropriate diagnostic approach and Upper airway cough syndrome, Asthma and Gastroesophageal reflex disease are the most common causes of disease to non-smokers. Chronic cough can be due to not one reason but various reasons and achieve good results by a systematic approach to diagnosis and a concrete treatment on the basis of the sufficient understanding of the underlying disease.

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Bioinformatics for the Korean Functional Genomics Project

  • Kim, Sang-Soo
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2000.11a
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    • pp.45-52
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    • 2000
  • Genomic approach produces massive amount of data within a short time period, New high-throughput automatic sequencers can generate over a million nucleotide sequence information overnight. A typical DNA chip experiment produces tens of thousands expression information, not to mention the tens of megabyte image files, These data must be handled automatically by computer and stored in electronic database, Thus there is a need for systematic approach of data collection, processing, and analysis. DNA sequence information is translated into amino acid sequence and is analyzed for key motif related to its biological and/or biochemical function. Functional genomics will play a significant role in identifying novel drug targets and diagnostic markers for serious diseases. As an enabling technology for functional genomics, bioinformatics is in great need worldwide, In Korea, a new functional genomics project has been recently launched and it focuses on identi☞ing genes associated with cancers prevalent in Korea, namely gastric and hepatic cancers, This involves gene discovery by high throughput sequencing of cancer cDNA libraries, gene expression profiling by DNA microarray and proteomics, and SNP profiling in Korea patient population, Our bioinformatics team will support all these activities by collecting, processing and analyzing these data.

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Rehabilitation of the Throwing Athlete (던지기 선수에서의 재활)

  • Youn, Te-Hyun;Moon, Young-Lae
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.6 no.2
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    • pp.77-82
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    • 2007
  • The thrower's shoulders require a delicate balance between mobility and functional stability. First step to successful nonoperative management is an accurate diagnostic approach. Rehabilitation program follows a well-organized, multiphase approach with focus on controlling painful inflammation, restoring muscle balance, obtaining joint flexibility, improving proprioception and neuromuscular control, and effectively returning to competitive pitching. In this article, the typical musculoskeletal profile of the overhead thrower and various rehabilitation programs for specific injuries are discussed.

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Useful of Magnetic Resonance Imaging in the Diagnosis and Surgical Plan of Intraperineal Lipoma in a Dog (자기공명영상이 개의 회음부 지방종의 진단 및 수술방법에 유용한 1예)

  • 송영성;장화석;김성미;김혜진;김순신;최치봉;김휘율
    • Journal of Veterinary Clinics
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    • v.21 no.1
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    • pp.58-61
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    • 2004
  • A 5-year old female shih-tzu referred to the veterinary Teaching Hospital, College of Veterinary Medicine, Konkuk University. The patient was presented with a mass of ventral to pubic region and intraperineal region. CBC, chemistry, x-ray, fine needle aspiration, biopsy and MRI was performed. The dog was definitively diagnosed as lipoma based on cytologic and histopathologic examination. In order to remove the mass, an approach with two direction was made. First, intraperineal region was removed about 40%, and then ventral to pubic was removed the remainder. And inserted penrose drain for obliterate dead space to prevent the accumulation of serous discharge. The dog is clinically normal and being monitored for development of any abnormal signs for the time being. In this case, diagnostic MRI was very useful procedure. it revealed accurate location of a lipoma and useful manner for decision of surgical approach to remove.

A Study on the Methods for Assessing Construct Validity (구성 타당성 평가방법에 관한 연구)

  • 이광희;이선규;장성호
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.22 no.50
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    • pp.1-9
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    • 1999
  • The purpose of this study is to establish a basis for assessing construct validity of measures used in organizational research. The classic Campbell and Fiske's(1959) criteria are found to be lacking in their assumptions, diagnostic information, and power. The inherent confounding of measurement error with systematic trait and method effects is a severe limitation for a proper interpretation of convergent and discriminant validity. The confirmatory factor analysis(CFA) approach overcomes most of the limitations found in Campbell and Fiske's(1959) method. However, the CFA approach confounds random error with unique variance specific to a measure. The second-order confirmatory factor analysis(SOCFA) was shown to harbor rather restrictive assumptions and is unlikely to be met in practice. The first-order, multiple-informant, multiple-item(FOMIMI) model is a viable option, but it may also be of limited use because of the large number measures.

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An Empirical Analysis on a Predictive Method of Systematic Segmentation in Volatile High-Tech Markets

  • Shin, Yonghee;Jeon, Hyori;Choi, Munkee;Han, Eoksoo;Jung, Sungyoung
    • ETRI Journal
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    • v.35 no.2
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    • pp.321-331
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    • 2013
  • High-tech markets are unpredictable owing to rapid technology innovation, diverse customer needs, high competition, and other elements. Many scholars have attempted to explain the uncertainty in high-tech markets using their own various approaches. However, sufficiently clear ways to predict diverse changes and trends in high-tech markets have yet to be presented. Thus, this paper proposes a new approach model, that is, systematic market segmentation, to give more accurate information. Using an empirical dataset from the mobile handset market in the Republic of Korea, we conduct our research model consisting of three steps. First, we categorize nine basic segments. Second, we test the stability of these segments. Finally, we profile the characteristics of the customers and products. We conclude that the approach is able to offer more diagnostic information to both practitioners and scholars. It is expected to provide rich information for an appropriate marketing mix in practice.