• Korean Journal of Applied Biomechanics
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• v.25 no.1
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• pp.85-94
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• 2015

Purpose : The purpose of this study was to investigate the influence on the ground reaction force parameters according to wearing positions of backpack for during stair ascending and descending. Methods : Participants selected as subject were consisted of young female(n=10) and performed stairs walks(ascending and descending) with 2 types of wearing position(front of trunk[FT], rear of trunk[RT]). Passive(Fz 1) and active(Fz 2) forces of the vertical GRF were determined from time function and frequency domain. Also shear forces(Fx, Fy 1, Fy 2), dynamic postural stability index(MLSI, APSI, VSI, DPSI), loading rate and center of pressure (${\Delta}COPx$, ${\Delta}COPy$, COP area) were calculated from time function and frequency domain. Results : Fx, Fy 1, Fy 2, and Fz 1 in GRF didn't show significant differences statistically according to the wearing positions of backpack(p>.05), but stair descending showed higher forces than that of stair ascending. Particularly, Fz 2 of stair ascending showed higher forces than that of stair descending(p<.001), RT types showed higher than that of FT types(p<.05). MLSI, APSI, VSI, and DPSI of stair descending showed the increased stability index than that of stair ascending(p<.05), MLSI of RT types showed the decreased stability index than that of FT types(p<.05). Loading rate didn't show significant differences statistically according to the wearing positions of backpack(p>.05), but stair descending showed higher loading rate than that of stair ascending(p<.001). Also, ${\Delta}COPx$ in stair descending showed the increased movement than that of stair ascending(p<.05). Conclusions : A backpack of 10 kg(10 kg(ratio of body weights $17.61{\pm}1.17%$) showed significantly change GRF parameters according to wearing positions during stair ascending and descending. If possible, we suggest that the dynamic stability, in case of stairs walking with a smaller weights can be further improved.

• Molecular & Cellular Toxicology
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• v.4 no.4
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• pp.338-347
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• 2008

Yeast RAD2, a yeast homolog of human XPG gene, is an essential element of nucleotide excision repair (NER), and its deletion confers UV sensitivity and NER deficiency. 6-Azauracil (6AU) sensitivity of certain rad2 mutants revealed that RAD2 has transcription elongation function. However, the fundamental mechanism by which the rad2 mutations confer 6AU sensitivity was not clearly elucidated yet. Using an insertional mutagenesis, PUF4 gene encoding a yeast pumilio protein was identified as a deletion suppressor of rad2${\Delta}$ 6AU sensitivity. Microarray analysis followed by confirmatory RT-qPCR disclosed that RAD2 and PUF4 regulated expression of HPT1 and URA3. Overexpression of HPT1 and URA3 rescued the 6AU sensitivity of rad2${\Delta}$ and puf4${\Delta}$ mutants. These results indicate that 6AU sensitivity of rad2 mutants is in part ascribed to impaired expression regulation of genes in the nucleotide metabolism. Based on the results, the possible connection between impaired transcription elongation function of RAD2/XPG and Cockayne syndrome via PUF4 is discussed.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.52 no.4
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• pp.458-468
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• 2007

To tolerate environmentally adverse conditions such as cold, drought, and salinity, plants often synthesize and accumulate proline in cells as compatible osmolytes. ${\Delta}^1$-Pyrroline-5-carboxylate synthetase(P5CS) catalyzes the rate-limiting step of proline biosynthesis from glutamate. Two complete genes, MtP5CS1 and MtP5CS2, were isolated from the model legume Medicago truncatula by cDNA cloning and bacterial artificial chromosome library screening. Nucleotide sequence analysis showed that both genes consisted of 20 exons and 19 introns. Alignment of the predicted amino acid sequences revealed high similarities with P5CS proteins from other plant species. The two MtP5CS genes were expressed in response to high salt and low temperature treatments. Semi-quantitative reverse transcription-polymerase chain reaction showed that MtP5CS1 was expressed earlier than MtP5CS2, indicating differential regulation of the two genes. To evaluate the reverse genetic effects of nucleotide changes on MtP5CS function, a Targeting Induced Local Lesions in Genomes approach was taken. Three mutants each were isolated for MtP5CS1 and MtP5CS2, of which a P5CS2 nonsense mutant carrying a codon change from arginine to stop was expected to bring translation to premature termination. These provide a valuable genetic resource with which to determine the function of the P5CS genes in environmental stress responses of legume crops.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.2
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• pp.409-422
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• 2013

For stability design and P-${\Delta}$ analysis of steel frames with semi-rigid connections, the explicit form of the exact tangential stiffness matrix of a generalized semi-rigid frame element having rotational and translational connections is firstly derived using the stability functions. And its elastic and geometric stiffness matrix is consistently obtained by Taylor series expansion. Next depending on connection types of semi-rigidity, the corresponding tangential stiffness matrices are degenerated based on penalty method and static condensation technique. And then numerical procedures for determination of effective buckling lengths of generalized semi-rigid frames members and P-${\Delta}$ and shortly addressed. Finally three numerical examples are presented to demonstrate the validity and accuracy of the proposed method. Particularly the minimum braced frames and coupled buckling modes of the corresponding frames are investigated.

• Mass Spectrometry Letters
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• v.10 no.1
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• pp.11-17
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• 2019

Drosophila melanogaster (fruits fly) is a representative model system widely used in biological studies because its brain function and basic cellular processes are similar to human beings. The whole head of the fly is often used to obtain the key function in brain-related diseases like degenerative brain diseases; however the biomolecular distribution of the head may be slightly different from that of a brain. Herein, lipid profiles of the head and dissected brain samples of Drosophila were studied using electrospray ionization-mass spectrometry (ESI-MS). According to the sample types, the detection of phospholipid ions was suppressed by triacylglycerol (TAG), or the specific phospholipid signals that are absent in the mass spectrum were measured. The lipid distribution was found to be different in the wild-type and the microRNA-14 deficiency model ($miR-14{\Delta}^1$) with abnormal lipid metabolism. A few phospholipids were also profiled by comparison of the head and the brain in two fly model systems. The mass spectra showed that the phospholipid distributions in the $miR-14{\Delta}^1$ model and the wild-type were different, and principal component analysis revealed a correlation between some phospholipids (phosphatidylethanolamine (PE), phosphatidylinositol (PI), and phosphatidylserine (PS)) in $miR-14{\Delta}^1$. The overall results suggested that brain-related lipids should be profiled using fly samples after dissection for more accurate analysis.

• Journal of the Korean Mathematical Society
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• v.52 no.3
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• pp.637-647
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• 2015

For generalized continued fraction (GCF) with parameter ${\epsilon}(k)$, we consider the size of the set whose partial quotients increase rapidly, namely the set $$E_{\epsilon}({\alpha}):=\{x{\in}(0,1]:k_{n+1}(x){\geq}k_n(x)^{\alpha}\;for\;all\;n{\geq}1\}$$, where ${\alpha}$ > 1. We in [6] have obtained the Hausdorff dimension of $E_{\epsilon}({\alpha})$ when ${\epsilon}(k)$ is constant or ${\epsilon}(k){\sim}k^{\beta}$ for any ${\beta}{\geq}1$. As its supplement, now we show that: $$dim_H\;E_{\epsilon}({\alpha})=\{\frac{1}{\alpha},\;when\;-k^{\delta}{\leq}{\epsilon}(k){\leq}k\;with\;0{\leq}{\delta}&lt;1;\\\;\frac{1}{{\alpha}+1},\;when\;-k-{\rho}&lt;{\epsilon}(k){\leq}-k\;with\;0&lt;{\rho}&lt;1;\\\;\frac{1}{{\alpha}+2},\;when\;{\epsilon}(k)=-k-1+\frac{1}{k}$$. So the bigger the parameter function ${\epsilon}(k_n)$ is, the larger the size of $E_{\epsilon}({\alpha})$ becomes.

• Journal of the Korean Ceramic Society
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• v.39 no.3
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• pp.222-225
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• 2002

Microwave dielectric properties of the layered and functionally graded materials (FGMs) of $Mg_{0.93}Ca_{0.07}TiO_3$ (MCT) and $(Ca_{0.3}Li_{0.14}Sm_{0.42})TiO_3$(CLST) were investigated as a function of the volume ratio of two components. Dielectric constant was decreased with an increase of the volume ratio of MCT which had a lower dielectric constant thant CLST. For the layered FGMs specimens, the difference of thermal expansion coefficients between two components induced thermal strain to dielectric layers, which was confirmed by the plot of ${\Delta}$k (X-ray diffraction peak width0 versus k (scattering vector) using the double-peak Lorentzian function, f(x). Quality factor of the specimens was affected by the thermal strain of dielectric layer, especially MCT layer. For the specimen with the volume ratio of MCT/CLST = 2, the qulaity factor of the specimen showed a minimum value due to the maximum thermal strain fo MCT layer.

• Journal of Sensor Science and Technology
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• v.8 no.1
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• pp.45-52
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• 1999

In this raper, an enhanced learning method is proposed for improving the learning speed of the error back propagation learning algorithm. In order to cope with the premature saturation phenomenon at the initial learning stage, a variation scheme of active functions is introduced by using higher order functions, which does not need much increase of computation load. It naturally changes the learning rate of inter-connection weights to a large value as the derivative of sigmoid function abnormally decrease to a small value during the learning epoch. Also, we suggest the hybrid learning method incorporated the proposed method with the momentum training algorithm. Computer simulation results show that the proposed learning algorithm outperforms the conventional methods such as momentum and delta-bar-delta algorithms.

• Proceedings of the Korean Association for Survey Research Conference
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• 2003.06a
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• pp.34-41
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• 2003

In many cases, the measurement error variances may be functions of the unknown true values or related covariates. This paper develops estimators of the parameters of a linear measurement error variance function based on wi thin-unit sample variaoces. This paper devotes to: (1) define measurement error scale factor $\delta$: (2) develop estimators of the parameters of the 1inear measurement error variance function under stratified multistage sampling design and small error conditions; (3) use propensity methods to adjust survey weights to account for possible selection effects at the replicate level. The proposed methods are applied to medical examination data from the U S Third National Health and Nutrition Examination Survey(NHANES III)

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.1
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• pp.85-90
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• 2007

We deposited thin films of ZnS(Zinc Sulphide), in which was used antireflection coating material of glasses-lens on silicon and slide-glass substrates using spin coating method, and measured spectra of ellipsometry angles ${\Delta}$ and ${\Psi}$ in the photon-energy range of 1.5~5.0 eV using a variable angle spectroscopic ellipsometer. The optical constants, refractive index and extinction coefficient, of ZnS were determined via the dispersion parameters extracted from the curve-fitting process based on Jellison-Modine dispersion function.