• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.11a
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• pp.28-33
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• 1993

Regulation of nerve growth factor (NGF)-induced neuronal differentiation by GTPase activating protein(GAP) and its mechanism were investigated in rat pheochromocytoma cell line, PCl2. Overexpression of GAP caused the delay in the onset of neurite outgrowth of PCl2 eel Is in response to NGF. GAP has been known to inhibit p21$\^$ras/, the activated form of which induces neuronal differentiation. Therefore, the activity of p21$\^$ras/ was compared in control cells and cells overexpressing GAP indirectly by measuring the activities of B-Raf and MAP kinase that are known to be positively regulated by p21$\^$ras/. Surprisingly, NGF-induced activities of these two proteins were the same in control eells and GAP-overexpressing cells. Activities of Trk, PLC-r and SMC that act at a site upstream to p21$\^$ras/ in NGF signal transduction pathway were not also affected by GAP overexpression. Interestingly, however, the extent of tyrosine phosphorylation of SNT was found to be remarkably low in cells overexpressing GAP. It has been shown previously that neurotrophins and not mitogens induce SNT tyrosine phosphorylation in PCl2 cells. Thus it is possible that the timing of NGF-induced neuronal differntiation may be in part regulated by SNT and the slower onset of neurite outgrowth in cells overexpressing GAP may be through the inhibition of SNT by GAP.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.04b
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• pp.273-277
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• 1995

Many hudraulic components have nonlinearities to some extent. These nonlinearities often cause the time delay, thus degrading the performance of the hydraulic control systems and making it difficult to modelthem. In this paper, a new vibration isolation control algorithm that eliminates the necessity of a sophiscated modeling of hydraulic system was proposed. The algotithm is a hybrid type control shecheme consisting of a linear controller and a hetero-synaptic neural network controller. Using this control scheme, simulations and experiments were performed for 1 DOF(Degree of freedom) and 2 DOF vibration isolation. The hybrid type control algorithm can isolate the base vibration signifcantly rather than linear control algorithm. And from the weights in hetero-synaptic neural network, we can get the 2nd equivalent differentialmodel of the hydraulic control system with on-line control operation. This equivalent model provides us with much information, such as stability and the characteristics of the control system.

• Journal of Sensor Science and Technology
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• v.21 no.3
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• pp.217-222
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• 2012

Optical coherence tomography(OCT) is a noninvasive optical imaging tool for biomedical applications. OCT can provide depth resolved two/three dimensional morphological images on biological samples. In this paper, we integrated an OCT system that was composed of an SLED(Superluminescent Light Emitting Diode, ${\lambda}_0$=1305 nm bandwith= 141 nm), a reference arm adopting a rapid scanning optical delay line(RSOD) to get high speed imaging, and a sample arm that used a micro electro mechanical systems(MEMS) scanning mirror. The sample arm contained a compact probe for imaging dental structures. The performance of the system was evaluated by imaging in-vivo human teeth with dental calculus, and the results indicated distinct appearance of dental calculus from enamel, gum or decayed teeth. The developed probe and system could successfully confirm the presence of dental calculus with a very high spatial resolution($6{\mu}m$).

• Journal of Internet Computing and Services
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• v.9 no.4
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• pp.1-10
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• 2008

In this paper, a packet scheduling algorithm, called the modified PLFS, is proposed for real-time traffic in IEEE 802.22 WRAN systems. The modified PLFS(Packet Loss Fair Scheduling) algorithm utilizes not only the delay of the Head of Line(HOL) packets in buffer of each user but also the amount of expected loss packets in the next-next frame when a service will not be given in the next frame. The performances of the modified PLFS are compared with those of PLFS and M-LWDF in terms of the average packet loss rate and throughput. The simulation results show that the proposed scheduling algorithm performs much better than the PLFS and M-LWDF algorithms.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.5
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• pp.1580-1584
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• 2010

In this paper, we made an analysis of the effective optical pulse stream generation. This is different from conventional approaches, which use fiber or waveguide delay line circuits. The optical pulse multiplication phenomenon occurs when the optical pulse's spectral width is greater than the transfer bandwidth of the coupler used. Therefore, the effective optical pulse stream generation can be controlled by using fiber couplers with different equivalent transfer bandwidths. The pulse separation spacing is controlled by number of cascaded coupler in optical loop mirror coupler scheme.

• Journal of Sensor Science and Technology
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• v.8 no.2
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• pp.108-114
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• 1999

Surface acoustic wave (SAW) device is very attractive for gas sensor applications because of their small size, low cost, high sensitivity, and good reliability. A dual delay line surface acoustic wave $NO_2$ gas sensors have been designed and fabricated on the $LiTaO_3$ piezoelectric single crystal substrate. The capacitance of the fabricated IDTs was 326.34pF at the frequency of 79.3MHz. The maximum reflection loss of the impedence-matched IDTs was -16.74dB at the frequency of 79.3MHz. The SAW oscillator was constructed and the stable oscillation was obtained by controlling the gain of rf amplifier properly. The oscillation frequency shift of the SAW oscillator to the $NO_2$ gas was 28Hz/ppm.

• Journal of Internet Computing and Services
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• v.9 no.2
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• pp.15-23
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• 2008

This paper proposes the new structural MOQ(Multiple Input/Output-Queued) switch which guarantees QoS while maintaining high efficiency and deals with the Anti-Empty algorithm which is new arbitration algorithm to be used for the proposed switch. The new structure of the proposed switch based on MIQ, MOQ is designed to have the same buffer speed as the external line speed. Also, the proposed switch makes it possible to remove the weak point of existing methods and introduces the new method of the MOQ operation to support QoS. Therefore, this switch is equal to the Output Queued switch in efficiency and delay, and guarantees the high-speed switching supporting QoS without cell loss.

• Proceedings of the KIEE Conference
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• 1997.07c
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• pp.1124-1126
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• 1997

The Unified Power Flow Controller(UPFC) with a series inverter and a shunt inverter ia able to control all three line Parameters(voltage, impedance and phase angle) and so UPFC technology has the potential to enhance the implementation and broad application of the FACTS concept with improved Performance. In this Paper, the UPFC is applied in order to improve the power flow oscillation damping. The modal performance measure is minimized in order to determine the optimal parameters of UPFC controller for damping Power flow oscillations. The dynamics of the injected voltage of UPFC is represented as a first order delay element. The UPFC controller used here is of the PIO type and the input signal to the controller is the active power flow through the UPFC. The effect of UPFC application to the Power system are analyzed from the stand point of power system oscillation damping.

• YAKHAK HOEJI
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• v.53 no.6
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• pp.368-376
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• 2009

DUR (Drug Utilization Review) originally referred to the evaluation of drug usage details: however DUR refers to the system used to support the services of prescribing and dispensing through linking from Health Insurance Review and Assessment (HIRA) Service in Korea. HIRA is going to begin the DUR enforcement for extending to nationwide coverage after pilot test. Objectives: The aims for this study were to evaluate and clarify the current opinions of the pharmacists for the recognition and acceptance rates before nationwide coverage concerning DUR system. Methods: A 16-question-questionnaire was developed and pilot tested. For 40 days of survey by both on-line and fax paper, it was carried out on 80 pharmacists working at community pharmacy in Goyang-si, Gyeonggi-do. Results: Most of answers were broadly positive and interested in begining the DUR system and kept in mind that the goal of DUR is safety guarantee for people. On the other hand, most of answerers worry that delay of patient waiting time and inharmonious communication with doctors in DUR processing can be a major obstacle to begin the DUR system. Conclusion: To solve several problems, the most important things are to make good reciprocal relationships between doctors and pharmacists, investigate intervention tool to shorten patient waiting time, and activate educational program of inspecting items for the pharmacists.

• Journal of the Korean Society for Precision Engineering
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• v.31 no.6
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• pp.497-504
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• 2014

The digital signage display is actively researched as the next generation of large FPD. To commercialize those digital signage display, the manufacturing cost must be downed with printing method instead of conventional photolithography. Here, we demonstrate a reverse offset printed TFT electrodes for the digital signage display. For the fabricated source/drain and gate electrode, we used Ag ink, silicone blanket, Clich$\acute{e}$ and reverse offset printer. We printed uniform TFT electrode patterns with narrow line width(10 ${\mu}m$ range) and thin thickness(nm range). In the end the printing source/drain and gate electrode are successfully achieved by optimization of experimental conditions such as Clich$\acute{e}$ surface treatment, ink coating process, delay time, off/set process and curing temperature. Also, we checked that the printing align accuracy was within 5 ${\mu}m$.