• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.27 no.4
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• pp.403-414
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• 2023

Backgrounds/Aims: Pancreatoduodenectomy (PD) is recommended in fit patients with a carcinoma (PDAC) of the pancreatic head, and a delayed resection may affect survival. This study aimed to correlate the time from staging to PD with long-term survival, and study the impact of preoperative investigations (if any) on the timing of surgery. Methods: Data were extracted from the Recurrence After Whipple's (RAW) study, a multicentre retrospective study of PD outcomes. Only PDAC patients who underwent an upfront resection were included. Patients who received neoadjuvant chemo-/radiotherapy were excluded. Group A (PD within 28 days of most recent preoperative computed tomography [CT]) was compared to group B (> 28 days). Results: A total of 595 patents were included. Compared to group A (median CT-PD time: 12.5 days, interquartile range: 6-21), group B (49 days, 39-64.5) had similar one-year survival (73% vs. 75%, p = 0.6), five-year survival (23% vs. 21%, p = 0.6) and median time-to-death (17 vs. 18 months, p = 0.8). Staging laparoscopy (43 vs. 29.5 days, p = 0.009) and preoperative biliary stenting (39 vs. 20 days, p < 0.001) were associated with a delay to PD, but magnetic resonance imaging (32 vs. 32 days, p = 0.5), positron emission tomography (40 vs. 31 days, p > 0.99) and endoscopic ultrasonography (28 vs. 32 days, p > 0.99) were not. Conclusions: Although a treatment delay may give rise to patient anxiety, our findings would suggest this does not correlate with worse survival. A delay may be necessary to obtain further information and minimize the number of PD patients diagnosed with early disease recurrence.

• Journal of Preventive Medicine and Public Health
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• v.20 no.1 s.21
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• pp.1-9
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• 1987

Sister chromatid exchanges (SCEs) observed by means of bromodeoxyuridine substitution and fluorescence plus Giemsa (FPG) technique were proposed as a sensitive and quantitative assay for mutagenicity and cytotoxicity in short-term cultures of phytohaemagglutinin (PHA)-stimulated human lymphocytes. Therefore, this study was carried out to investigate the relation between anticancer agents and cytotoxic effects. Chromosomal analysis was performed on metaphase cells that had divided one, two, or three or more times after treatment for SCEs, mitotic indices (MI) and cell cycle kinetics by FPG technique. The results indicate that anticancer agents led to a dose dependent increase in SCE frequency except methotrexate. But, highly inhibited mitotic indices and delayed cell cycle kinetics were observed except for cyclophosphamide. The author suggest that the difference of SCE frequency is due to the differences in the cytotoxic action of anticancer agents, but although the induction of SCEs has a correlation with cell cycle delay, in some cases the induction of SCEs is not always related to cell cycle delay because of different cytotoxic action of anticancer agents.

• Journal of the korean academy of Pediatric Dentistry
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• v.41 no.4
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• pp.328-334
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• 2014

Gingival fibromatosis is a rare oral condition that is characterized by proliferative fibrous overgrowth of the attached gingiva, the marginal gingiva, and the interdental papilla, typically presenting in the growth period. A case of a 27-month-old girl with a generalized severe gingival overgrowth is described herein. The patient had no known systemic disease, but enlarged gingival tissue had gradually covered her teeth. The excess gingival tissue was removed by conventional gingivectomy, which involved extraction of the retentive primary teeth under general anesthesia when she was 5 years old. Post surgical follow-up at 18 months after the surgery demonstrated no recurrence. Resectional surgery of the enlarged gingival tissue is the treatment choice for gingival fibromatosis, although there is a high risk of recurrence. More frequent professional follow-ups and oral hygiene instruction might be required. A delay in the surgical treatment may have significant consequences for the patient, such as primary dentition retention and consequent delay in the eruption of the permanent teeth, difficulties in mastication and phonation, malpositioning of the teeth, and psychological problems. Early surgical treatment should be performed according to the severity of enlargement.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.5
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• pp.209-220
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• 2013

Handover is the technology to minimize data lose of mobile devices and make continuous communication possible even if the device could be moved from one digital cell site to another one. That is, it is a function that enables the mobile user to avoid the disconnection of phone conversations when moving from a specific mobile communication area to another. Today, there are a lot of ongoing researches for fast and efficient hand-over, in order to address phone call's delay and disconnection which are believed to be the mobile network's biggest problems, and these should essentially be resolved in all mobile networks. Thanks to recent technology development in mobile network, the LTE network has been commercialized today and it has finally opened a new era that makes it possible for mobile phones to process data at high speed. In LTE network environment, however, a new authentication key must be generated for the hand-over. In this case, there can be a problem that the authentication process conducted by the hand-over incurs its authentication cost and delay time. This essay suggests an efficient key caching hand-over method which simplifies the authentication process: when UE makes hand-over from oMME to nMME, the oMME keeps the authentication key for a period of time, and if it returns to the previous MME within the key's lifetime, the saved key can be re-used.

• Land and Housing Review
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• v.8 no.3
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• pp.189-200
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• 2017

The work breakdown structure and the precedence relations by work activity are very important because they are the basic data for estimating the construction duration in the construction work. However, there is no standard to accurately estimate the construction duration since the size of the school facilities construction is smaller than the general construction work. Therefore, some schools are unable to open in March or September and the delay of the construction duration can cause damage to the students. To solve this problem, this study developed a work breakdown structure of school facilities construction work and analyzed the precedence relations by work activities. The work breakdown structure of the school facilities construction is composed of three steps. The operations corresponding to level 1 and level 2 are as follows. (1) 2 preparatory work categories; preparation period and temporary construction. (2) 17 architectural work categories; temporary construction, foundation & pile work, reinforced concrete work, steel roof work, brick work, plaster work, tile work, stone work, waterproof construction, wood work, interior construction, floor work, metal work, roof work, windows construction, glazing work and paint construction. (3) 7 mechanic and fire work categories; outside trunk line work, plumbing work, air-conditioning equipment work, machine room work, city gas plumbing work, sanitation facilities and inspection & test working. (4) 4 civil work categories; wastewater work, drainage work, pavement work and other work. (5) 1 landscaping work categories; planting work. The work breakdown structure was derived from interviews with experts based on the milestones and detailed statements of existing school facilities. The analysis of precedence relations by school facilities work activity utilized PDM(Precedence Diagramming Method)which does not need a dummy and the relations were applied using FS(Finish to Start), FF(Finish to Finish), SS(Start to Start), SF(Start to Finish). The analysis of this study shows that if one work activity is delayed, the entire construction duration may be delayed because the majority of the works are FS relations. Therefore, it is necessary to use the Lag at the appropriate time to estimate the standard construction duration of the school facility construction. Lag is a term used only in the PDM method and it is used to define the relationship between the predecessor and the successor in creating the network milestone. And it means the delay time applied to the two work activities. The results of this study can reasonably estimate the standard construction duration of school facilities and it will contribute to the quality of the school facilities construction.

• Journal of Wetlands Research
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• v.21 no.3
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• pp.191-198
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• 2019

High impervious surfaces increase the surface runoff during rainfall and reduces the underground infiltration thereby leading to water cycle distortion. The distortion of water cycle causes various urban environmental problems such as urban flooding, drought, water pollutant due to non-point pollution runoff, and water ecosystem damage. Climate change intensified seasonal biases in urban rainfall and affected urban microclimate, thereby increasing the intensity and frequency of urban floods and droughts. Low impact development(LID) technology has been applied to various purposes as a technique to reduce urban environmental problems caused by water by restoring the natural water cycle in the city. This study evaluated the contribution of hydrologic characteristics and water cycle recovery after LID application using long-term monitoring results of various LID technology applied in urban areas. Based on the results, the high retention and infiltration rate of the LID facility was found to contribute significantly to peak flow reduction and runoff delay during rainfall. The average runoff reduction effect was more than 60% at the LID facility. The surface area of the LID facility area ratio(SA/CA) was evaluated as an important factor affecting peak flow reduction and runoff delay effect.

• The Journal of the Acoustical Society of Korea
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• v.25 no.6
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• pp.277-281
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• 2006

This paper presents a method for the automatic recognition of pitch accents over syllables. The method that we propose is based on the time-delay recursive neural network (TDRNN). which is a neural network classifier with two different representation of dynamic context: the delayed input nodes allow the representation of an explicit trajectory F0(t) along time. while the recursive nodes provide long-term context information that reflects the characteristics of pitch accentuation in spoken English. We apply the TDRNN to pitch accent recognition in two forms: in the normal TDRNN. all of the prosodic features (pitch. energy, duration) are used as an entire set in a single TDRNN. while in the distributed TDRNN. the network consists of several TDRNNs each taking a single prosodic feature as the input. The final output of the distributed TDRNN is weighted sum of the output of individual TDRNN. We used the Boston Radio News Corpus (BRNC) for the experiments on the speaker-independent pitch accent recognition. π 1e experimental results show that the distributed TDRNN exhibits an average recognition accuracy of 83.64% over both pitch events and non-events.

• Journal of the Korean Wood Science and Technology
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• v.44 no.5
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• pp.785-808
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• 2016

The objective of this study was to investigate the effect of the short-term weathering on the flame retardant performance of wood coated with Dancheong. Flame retardants were applied on the Dancheong coated Korean red pine. Flame retardants applied panels were layed at the two conditions of outdoor exposure and artificial aging to assess the reliability of artificial aging. Flame retardants used were commercial products developed for historical wooden buildings. Scanning electron micrographs revealed the forming of carbonized membrane by melting of flame retardant on wood surface. These carbonized membranes may help delay the further combustion of wood. Flame retardant performance was assessed by measuring heat release rate (HRR) and total heat release (THR) by cone calorimetry. There was no difference in flame retardant performance between before and after 6-month outdoor exposure tests. And also no difference in flame retardant performance between before and after 2-week artificial aging which corresponds to 6-month outdoor exposure. Both tests showed the similar results of combustion characteristics.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.36T no.4
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• pp.71-81
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• 1999

We propose a new CPLD(Complexity Programmable Logic Device) technology mapping algorithm improving run-time under time constraint. In our technology mapping algorithm, a given logic equation is constructed as the DAG(Directed Acyclic Graph) type, then the DAG is reconstructed by replicating the node that outdegree is more than or equal to 2. As a result, it makes delay time and the number of CLBs, run-time to be minimized. Also, after the number of multi-level is defined and cost of each nodes is calculated, the graph is partitioned in order to fit to k that is the number of OR term within CLB. The partitioned nodes are merged through collapsing and bin packing is performed in order to fit to the number of OR term within CLB(Configurable Logic Block). In the results of experiments to MCNC circuits for logic synthesis benchmark, we can shows that proposed technology mapping algorithm reduces run-time and the number of CLBs much more than the TEMPLA.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.5 no.2
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• pp.86-94
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• 2000

In order to extract the spatio-temporal characteristics of long-term variability of the net heat flux on the sea surface in the East Asian marginal seas, empirical orthogonal function (EOF) analysis was conducted using data set calculated every 12 hours interval during 1978-1995. Among the first three modes explaining 73% of the total variance, the first mode having high peak at 1 year period indicates high variability area around the Sandong Peninsula and central and northeastern part of the East Sea. In the second mode which has spatial distribution of dipole type at the north and south, the peaks appear at 3.6 year and 2.3 year cycles. Time coefficient of the second EOF is believed to have close relation with the E1 Nino and has out-of-phase variation with NINO3 SST. Lagged correlation between NINO3 SST and time coefficient of the second EOF indicates four month time delay in the NINO3 SST. In the third mode which has opposite sign at the east and west, the periodicity of 6-9 year cycle has relatively clear appearance compared to other two EOFs. Also, high heat loss exceeding 800 W/$m^{2}$ in winter time occured at the south part of the Sandong Peninsula and Vladivostok. It reveals more frequent occurrence of about two times at the Sandong Peninsula than Vladivostok. The event is concentrated in January at Vladivostok, but it occurs primarily in December and January at the Sandong Peninsula.