• Title/Summary/Keyword: degradation agent

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A Theoretical Approach on the Migration of a Chelating Radionuclide in Porous Medium (다공성 매질에서의 착화하는 방사성핵종의 이동에 대한 이론적 접근)

  • Baik, Min-Hoon;Lee, Kun-Jai
    • Journal of Radiation Protection and Research
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    • v.17 no.2
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    • pp.49-59
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    • 1992
  • A new model was developed in order to investigate the effects of chelating agents on the migration of a radionuclide in the form of ion or chelate. The migration behavior of the chelated radionuclide was analyzed by formulating a convective-dispersion transport equation which included a degradation of chelating agent and chelated radionuclide. The mathematical model was analytically solved and checked with the existing retardation factor. The results show that the migration velocity of the chelated radionuclide was much faster than the ionic one due to the decreased retardation. Therefore, it was concluded that a new remedial action should be developed to reduce the generation and release of chelating agents from the nuclear power plant into the environment.

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Prenatal effect of pyrantel pamoate on several hematological parameter of offspring in mice

  • Abdulwahab.A.Noorwall;Ghazi M. Al-Hachim;Award -Omar
    • Archives of Pharmacal Research
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    • v.9 no.2
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    • pp.87-91
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    • 1986
  • In attempt to develop a drug delivery system using serum albumin microspheres, bovine serum albumin microspheres containing antitumar agent. Cytarabine, were prepared. The shape, surface characteristics, size distribution, behavior of in vivo distribution, drug release behavior, and degradation of albumin microsphers in animal liver issue homogenate and proteolytic enzyme were investigated. The shape of albumin microspheres was spherical and the surface was smooth and compact. The size distribution of the albumin microspheres was effected by dispertion forces during emulsification and albumin concentration. Distribution of albumin microspheres after imtravenous administration in rabbit was achieved immediately. In vitro, albumin microsphere matrix was so hard that it retained most of cytarabine except initial burst during the first 10 minutes, and the level of drug release during the initial burst was affected by heating temperature, drug/albumin microsphere matrix was so hard that it retained most of cytarabine except initial burst during the first 10 minutes, and the level of drug release during the initial burst was affected by heating temperature, drug/albumin concentration ratio and size distribution. After drug release test, the morphology of albumin microspheres was not changed. Albumin microsphere matrix was degraded by the animal liver issue homogenate and proteolytic enzyme. The degree of degradation was affected by heating temperature.

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Development of specific organ-targeting drug delivery system 1

  • Kim, Chong-Kook;Jeong, Eun-Ju;Yang, Ji-Sun;Kim, Seung-Hwan;Kim, Yang-Bae
    • Archives of Pharmacal Research
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    • v.8 no.3
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    • pp.159-168
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    • 1985
  • In attempt to develop a drug delivery system using serum albumin microspheres, bovine serum albumin microspheres containing antitumor agent, cytarabine, were prepared. The shape, surface characteristics, size distribution, behavior of in vitro distribution, drug release behaior, and degradation of albumin microspheres in animal liver tissue homogenate and proteolytic enzyme were investigated. The shape of albumin microspheres was spherical and the surface was smooth and compact. The size distribution of the albumin microspheres was affected by dispersion forces during emulsification and albumin concentration. Distribution of albumin mirospheres after intravenous administration in rabbit was achieved immediately. In vitro, albumin microsphere matrix was so hard that it retained most of cytarabine except initial burst during the first 10 minutes, and the level of drug release during the initial burst was affected by heating temperature, drug/albumin concentration ratio and size distribution. After drug release test, the morphology of albumin micropheres was not changed. Albumin microsphere matrix was degraded by the rabbit liver tissue homogenate and proteolytic enzyme. The degree of degradation was affected by heating temperature.

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Accelerated Formation of Surface Films on the Degradation of LiCoO2 Cathode at High Temperature (표면 피막 형성이 LiCoO2 양극의 고온 열화에 미치는 영향)

  • Sung, Jong Hun;Hasan, Fuead;Yoo, Hyun Deog
    • Journal of the Korean Electrochemical Society
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    • v.23 no.3
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    • pp.57-65
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    • 2020
  • It is crucial to investigate the thermal degradation of lithium-ion batteries (LIBs) to understand the possible malfunction at high temperature. Herein, we investigated the effects of surface film formation on the thermal degradation of lithium cobalt oxide (LiCoO2, LCO) cathode that is one of representative cathode materials. Cycling test at 60℃ exhibited poorer cycleability compared with the cycling at 25℃. Cathodes after the initial 5 cycles at 60℃ (60-LCO) exhibited higher impedance compared to the cathode after initial 5 cycles at 25℃ (25-LCO), resulting in the lower rate capability upon subsequent cycling at 25℃, although the capacity values were similar at the lowest C-rate of 0.1C. In order to understand degradation of the LCO cathode at the high temperature, we analyzed the cathodes surface using X-ray photoelectron spectroscopy (XPS). Among various peaks, intensity of lithium hydroxide (LiOH) increased substantially after the operation at 60℃, and the C-C signal that represents the conductive agent was distinctly lower on 60-LCO compared to 25-LCO. These results pointed to an excessive formation of cathode-electrolyte interphase including LiOH at 60℃, leading to the increase in the resistance and the resultant degradation in the electrochemical performances.

Degradation Characteristics of Cross-linked Hyaluronic Acid Membrane (가교된 히아루론산 막의 분해 특성)

  • Cheong, Seong-Ihl;Cho, Gu-Hyun
    • Membrane Journal
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    • v.19 no.4
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    • pp.310-316
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    • 2009
  • The degradation characteristics of cross-linked lactide/hyaluronic acid (LA/HA) membranes were investigated for purpose of applying to tissue engineering. The lactide/hyaluronic acid cross-linked with 1,3-butadiene diepoxide (BD) and 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) was degradated in deionized water in water bath at $37^{\circ}C$. As the LA/HA mole ratio or crosslinking agent concentration decreased, the degradation rate of the crosslinked membranes increased. In order to investigate the structure change of the membrane in the degradation process, the control sample and 3, 6, 9 days-degradated samples were analysed by the nuclear magnetic resonance spectroscopy. In case of the membranes crosslinked with EDC, the HA-EDC bonding structure was degradated slowly whereas the HA-LA bonding structure was degradated quickly and dissappeared completely after 6 days. In case of the membranes crosslinked with BD, all the crosslinked bonding structure degradated slowly. The HA-BD bonding structure maintained its original state about 89, 83% in case of 3, 6 days-degardated samples respectively whereas the HA-LA bonding structure maintained its original state about 83, 65%. The scanning electron microscopy of the degradated membranes showed that the pore density in the surface, and the structure in the surface and cross section, of the before and after-degradation membranes did not change greatly, so the membranes was shown to be applied to materials for tissue engineering.

Effect of glycerine treatment on the properties of paper (글리세린 처리에 의한 종이의 물성 변화)

  • Park, Se-Jin;Cha, Ji-Young;Kim, Hak-Sang;Kim, Bong-Yong
    • Current Research on Agriculture and Life Sciences
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    • v.24
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    • pp.55-59
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    • 2006
  • This study was carried out to investigate the influence of glycerine on the properties of paper. Two types of glycerine treatment were used. First type, when making handsheets, glycerine was added in the plup slurry. Second type, copying paper was soaked in glycerine solution. Microwave treatment was used for the test of paper degradation. The obtained results were summarized as follows: 1. The glycerin was very effective to improve the property of softness. 2. The glycerine was helpful to increase sizing performance of paper as a fixing agent of sizing emulsion. 3. Curl tester was comparatively useful for the measuring of sizing degree.

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The Production and Enzymatic Properties of Extracellular Chitinase from Pseudomonas stutzeri YPL-1, as a Biocontrol Agent

  • Lim, Ho-Seong;Kim, Sang-Dal
    • Journal of Microbiology and Biotechnology
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    • v.4 no.2
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    • pp.134-140
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    • 1994
  • An antagonistic bacterium Pseudomonas stutzeri YPL-1 liberated extracellular chitinase and $\beta$-1,3-glucanase which are key enzymes in the decomposition of fungal hyphal walls. The lytic enzymes caused abnormal swelling and retreating at the hyphal tips of plant pathogenic fungus Fusarium solani in a dual culture. Scanning electron microscopy revealed the hyphal degradation of F. solani in the regions interacting with P. stutzeri YPL-1. The production of chitinase and properties of a crude preparation of the enzyme from P. stutzeri YPL-1 were investigated. Peak of the chitinase activity was detected after 4 hr of cultivation. The enzyme had optimum temperature and pH of 50$^{\circ}C$ and pH 5.3, respectively. The enzyme was stable in the pH range of 3.5 to 6.0 up to 50$^{\circ}C$. The enzyme was significantly inhibited by metal compounds such as $HgCl_2$, but was stimulated by $CoCl_2$. P. stutzeri YPL-1 produced high levels of the enzyme after 84 hr of incubation. Among the tested carbon sources, chitin was the most effective for the enzyme production, at the concentration level of 3%. As a source of nitrogen, peptone was the best for the enzyme production, at the concentration level of 4%. The maximum amount of enzyme was produced by cultivating the bacterium at a medium of initial pH 6.8.

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Thermal Behavior of Hwangto and Wood Flour Reinforced High Density Polyethylene (HDPE) Composites

  • Lee, Sun-Young;Doh, Geum-Hyun;Kang, In-Aeh
    • Journal of the Korean Wood Science and Technology
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    • v.34 no.5
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    • pp.59-66
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    • 2006
  • The thermal properties of wood flour, Hwangto, and maleated polyethylene (MAPE) reinforced HDPE composites were investigated in this study. The thermal behavior of reinforced wood polymer composites was characterized by means of thermogravimetric (TGA) and differential scanning calorimetric (DSC) analyses. Hwangto and MAPE were used as an inorganic filler and a coupling agent, respectively. According to TGA analysis, the increase of wood flour level increased the thermal degradation of composites in the early stage, but decreased in the late stage. On the other hand, Hwangto reinforced composites showed the higher thermal stability than virgin HDPE, from the determination of differential peak temperature ($DT_p$). Decomposition temperature of wood flour and/or Hwangto reinforced composites increased with increase of heating rate. From DSC analysis, melting temperature of reinforced composites little bit increased with the addition of wood flour or Hwangto. As the loading of wood flour or Hwangto to HDPE increased, overall enthalpy decreased. It showed that wood flour and Hwangto absorbed more heat energy for melting the reinforced composites. Hwangto reinforced composites required more heat energy than wood flour reinforced composites and virgin HDPE. Coupling agent gave no significant effect on the thermal properties of composites. Thermal analyses indicate that composites with Hwangto are more thermally stable than those without Hwangto.

An Integrated Management Scheme for Wired and Wireless Networks Using Mobile Agents (이동 에이전트를 이용한 유무선 네트워크의 통합관리 기법)

  • Na, Ho-Jin;Cho, Kyung-San
    • Journal of the Korea Society of Computer and Information
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    • v.15 no.11
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    • pp.117-124
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    • 2010
  • Appling centralized network management architecture SNMP(Simple Network Management Protocol) to wireless networks causes the network overhead, NAT(Network Address Translation) problem on AP, and performance degradation of mobile nodes. In this paper, we propose an integrated management scheme for wired and wireless networks using mobile agents in order to solve above problems. In our proposed scheme, SNMP is applied to manage wired networks and MAs of SNMP are implemented in APs or wireless nodes to manage wireless networks. In addition, we propose a method to reduce the redundant OID information within SNMP response messages. Through the analysis, we show that our proposal resolves the given problems and reduces the processing delay of the wireless nodes.

Effects of a Radiation Crosslinking on a Drawn Microporous HDPE Film with a Nucleating Agent

  • Park, Jong-Seok;Gwon, Sung-Jin;Lim, Youn-Mook;Nho, Young-Chang
    • Macromolecular Research
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    • v.17 no.8
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    • pp.580-584
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    • 2009
  • The effects of crystallinity and radiation crosslinking on the physical properties of a microporous high density polyethylene (HDPE) film with Millad3988 as a nucleating agent were investigated. The pores of the HDPE film were affected by the crystallinity. The crystallinity of the HDPE films increased with increasing Millad3988 amount up to 0.1 wt% but decreased with further addition. The mechanical characteristics of the HDPE containing Millad3988 films improved with increasing irradiation dose up to 50 kGy, but decreased at 75 kGy due to severe degradation. The thermal shrinkage behavior of the HDPE films decreased with increasing radiation dose up to 50 kGy. The porosity of the stretched HDPEIMillad3988 films after ${\gamma}$-ray radiation increased with increasing y-ray radiation dose up to 50 kGy. The pores of the irradiated films were formed more easily by a stretching due to the formation of a crosslinked structure.