• Toxicological Research
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• v.13 no.3
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• pp.183-186
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• 1997

Acute toxicity of pectenotoxin 2 (PTX2) was examined in mice. Treatment of mice with a toxic dose of PTX2 resulted in clinical signs such as ataxia, cyanosis and an abrupt decrease in body temperature. Histopathological studies revealed that the liver is the major target organ for PTX2. Activities of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and sorbitol dehydrogenase (SDH) were significantly elevated by PTX2 administration. Glucose-6-phosphatase activities were not changed by the treatment. The PTX2 treatment decreased relative liver weight without changing the body weight. The effect of PTX2 on hepatic drug metabolizing enzyme system was determined. An ip dose of PTX2 (200 $\mu$g/kg) induced a significant decrease in the hepatic microsomal protein content. Cytochrome P-450 content, cytochrome b$_5$ content, NADPH cytochrome c reductase, aminopyrine N-demethylase activities, or hepatic glutathione content were not altered by PTX2 treatment.

• Journal of Nutrition and Health
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• v.26 no.1
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• pp.76-88
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• 1993

Maternal body weight, skinfold thickness and circumference measurements were examined in 23 lactating women and 10 nonlactating women longitudinally from 1 week to 12 weeks postpartum. The dietary intakes of Korean lactating and nonlactating women were measured by 24-hour recall method and effects of maternal energy intake on body weight change were analyzed by Pearson correlation. The mean daily energy intake of breast-feeding(BF, n=12), combination of breast and formula-feeding (CF, n=11), and formula-feeding (FF, n=10) mothers were 1941kcal, 187kcal and 1727kcal, respectively. A significant decrease in weight was observed at all group. Weight losses at 12 weeks of postpartum in BF, CF and FF motheres were 3.18kg, 3.91kg and 5.15kg respectively. Weight losses increased as calorie intake decreased (${\gamma}$2=0.3803, p<0.05). The skinfold thickness and circumferences on all regions were decreased significantly except triceps and upper arm circumferences. However, there were no significant differences between lactating and nonlactating women. Anthropometric measurements decreased at the trunk but not at the limbs. Weight change was significantly correlated with changes of the scores for proximal circumference (${\gamma}$2=0.4999, p<0.05). There results suggest that lactation does not promete weight loss in well-nourished women and that the Korean RDA for energy in lactation may be too high.

• Women's Health Nursing
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• v.6 no.1
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• pp.129-141
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• 2000

The purpose of this study is to investigate the relationship between eating disorders, body image, and self-esteem of high school girls. Data were analysed by SPSS/PC using frequency, percentage, mean, standard deviation, ANOVA, & Pearson correlation coefficient. The results of this study are as follows. 1. The mean of body weight and height of the subjects were 52.49kg, 161.16cm. As defined by BMI, the obese subjects were very rare(2.1%) and the rest(97.9%) was under weight or normal. 2. More than 53% of the subjects perceived their weight as overweight, while 2.1% of the women were obese as defined by BMI. Ninety-three percent of the subjects were not satisfied with their body shape. 3. For the need for weight control, subject's own judgement(70.8%) was the highest percentage. High percentages of the women reported a decrease in the amount of eating(22.9%), and an increase in the amount of exercise(52.8%) as effective methods of weight control. 4. The total mean score of anorexia nervosa was higher than bulimia nervosa. 5. The scores of eating disorders did not differ significantly by the BMI score : The score of eating disorders was highest in the group os the overweight. 6. The score s of body image did not differ significantly by the BMI score : The score of body image was highest in the group of the overweight. 7. No significant difference was found in over all self esteem scores according to the BMI scores. 8. There was high positive correlation between BMI and eating disorders(r=.2158, p=.0094), between self-esteem and body image(r=.4288, p=.0001), and positive correlation between BMI and self-esteem(r=.1569, p=.0604), and between BMI and body image(r=.1354, p=.1056).

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.5
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• pp.1220-1230
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• 2016

The purpose of this study is to investigate the effect of 20s university student bodybuilders' protein intake differences with resistant exercise(weight training) by 12 weeks on solt lean mass and body composltion. Natural protein(Chicken breast meat) intake group and Whey protein isolates(WPI) intake group are the experimental groups. Conventional meal intake group is the control group. This study proposes a efficient protein diet for weight training. The results were as follows. In the experimental group(natural protein intake), muscle mass and lean body mass was significantly increased, but body fat percentage was significantly decreased. In the experimental group(WPI intake), muscle mass and lean body mass was significantly increased, but body fat percentage was significantly decreased. In the control group(conventional meal intake), muscle mass and lean body mass was insignificantly increased, but body fat percentage was insignificantly decreased. In addition, there was not a significant difference among intake groups, and also not a differentiated effect between natural protein and WPI intake. In conclusion, natural protein and WPI made muscle mass and lean body mass rise, body fat percentage reduced effectively. Only WPI intake(without natural protein intake) was the efficient mean to increase muscle mass and lean body mass, and to decrease body fat percentage.

• Journal of Food Hygiene and Safety
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• v.12 no.4
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• pp.271-276
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• 1997

The acute oral toxicity of organogermanium, Ge-132 was evaluated in rats andmice. The changes of body weight and clinical signs were observed for 14 days after the oral administration of Ge-132, from 0.31 g/kg up to 5 g/kg for SD rats and from 1.25 g/kg up to 5 g/kg for ICR mice. No death and toxic effects were observed for 14 days. The body weight of rats was significantly decreased 1 day after the administration in the maximum dosing group, but the decrease of body weight returned to control level 3 days after dosing. No significant changes in 132. Therefore, Ge-132 has no special toxic effects up to 5 g/kg, and LD* values of Ge-132 Ge-132 are above 5 g/kg in rats and mice.

• Journal of Nutrition and Health
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• v.36 no.5
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• pp.483-490
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• 2003

Chitosan, hydroxycitrate and L-carnitine have been known to be antiobesity components. The purpose of this study was to evaluate the combined effects of chitosan, hydroxycitrate and L-carnitine mixture as a potential antiobesity supplement in overweight women. Pre-menopausal healthy females who were overweight (percent ideal body weight > 110) were included in this study. Forty-nine subjects randomly received a placebo (n = 25) or antiobesity-supplement (n = 24), which was a mixture of chitosan, hydroxycitrate, and L-carnitine. Before and after the eight-week experimental period, anthropometric parameters, blood components and computerized tomography were measured. At baseline, the two groups were well matched in terms of age, body mass index and lipid profile. After the eight weeks of potential antiobesity supplementation, the subjects' body fat percent had decreased significantly (p < 0.001) by 5.6% (39.1 $\pm$ 1 vs 36.9 $\pm$ 1%) while lean body mass increased (p < 0.01). Vsceral fat area at the L4 vertebra decreased significantly (p < 0.01) by 8.6% in the supplemented group and the total fat area at the L4 vertebra showed a tendency to decrease (p = 0.051) by 2.4%. Also, in the group given the antiobesity-supplement rather than the placebo, the fasting triglyceride level decreased significantly (p < 0.05) by 10.0%. In addition, serum total cholesterol levels in the antiobesity-supplement group showed a tendency to decrease (p=0.159) by 2.7% (194 $\pm$ 6 vs 189 $\pm$ 6 mg/dl). No side effects were found in either group during the intervention. In conclusion, the present study demonstrated that taking a mixture of chitosan, hydroxycitrate, and L-carnitine as a potential antiobesity supplement for eight weeks produced advantageous changes in the weight and visceral fat accumulation of overweight women without any side effects. (Korean J Nutrition 36(5): 483~490, 2003)

• Journal of Life Science
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• v.13 no.4
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• pp.448-456
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• 2003

The purpose of this study was to determine changes in their cardiorespiratory function and body composition in female workers after aerobic exercise and circuit weight training. The subjects of this study were 16 female workers in B city and was divided into exercise and control groups which were composed of 8 people respectively. The members of exercise group had aerobic exercise and circuit weight training an hour a day, 5 days per week, for 8 weeks while controled group did not. Both groups were pretested and posttested, and the results of this study on cardiorespriatory function and body composition are as follows. Exercise group showed significant decrease in heart rate at rest(p<.001). Exercise group showed significant increase in the oxygen uptake at rest, in the maximum oxygen uptake and in the vital capacity(p<.001). Exercise group showed significant decrease in the %fat and fat(p<.001). Exercise group showed significant increase in the %LBM and LBM(p<.001).

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.3
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• pp.632-637
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• 1999

The purposes of this study is to investigate the effect of Rhus chinensis gall extract on liver function, plasma lipid composition and antioxidant system in the obese rats with high fat diet for seven weeks. Thirty two male rats of Sprague Dawely strain were divided into four groups. they are normal group (basal diet), control group(high fat diet), III group(high fat diet with Rhus chinensis gall extract 25mg/kg body weight per day) and IV group(high fat diet with Rhus chinensis gall extract 250mg/kg body weight per day). Rats in III group and IV group were administered with Rhus chinensis gall extract accordingly. Weight gains showed a tendency to decrease in rat with Rhus chinensis gall extract group but showed no differences among treatment groups. Food intake and Food efficiency ratio were not significantly different among treatment groups. Plasma total cholesterol showed a tendency to decrease in Rhus chinensis gall extract group. HDL cholesterol showed a tendency to decrease in 25mg/kg of Rhus chinensis gall extract group. However, in the 250mg/kg of Rhus chinensis gall extract group, these values showed no significant difference compared to the control group (p<0.05). GPT activities showed no significant difference among treatment groups. GOT activities showed a tendency to decrease in the groups of Rhus chinensis gall extract groups. Lipid peroxide level was significantly higher in control group than those of normal group. In Rhus chinensis gall extract groups, lipid peroxide level showed a tendency to decrease, but glutathione peroxidase activity was progressively increased. Results of our research in this paper show that Rhus chinensis gall extract might improve liver function, antioxidant system and plasma lipid composition in rats with high fat diet.

• Journal of Korean Academy of Nursing
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• v.36 no.8
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• pp.1359-1366
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• 2006

Purpose. This study was done to determine the effects of weight management program using self-efficacy in middle-aged obese women. The study also attempted to measure the effects of the program on the weight efficacy lifestyle, body composition, and depression. Method. The research design of this study was a nonequivalent control group pretest-posttest design. The experimental group consisted of 21 middle-aged obese women and another 21 middle-aged obese women in the control group. The women in the experimental group participated in the weight management program for 12 weeks using self-efficacy. The weight management program using self-efficacy included education on effects of exercise for weight control, aerobic exercise program, muscle training and counseling through the telephone. Results. After 12 weeks of participation in the program, BMI (p <.0001), body fat % (p <.0001), abdominal fat (p <.0001), in the experimental group were significantly decreased compared to the control group. Weight self-efficacy lifestyle (p <.0001) and depression (p =.006) in the experimental group were significantly improved after the program compared to the control group. According to these findings, weight management program self-efficacy for middle-aged obese women could increase weight efficacy lifestyle, and decrease depression, BMI, body fat, and abdominal fat. Conclusion. The result also suggested that the increasing weight efficacy and lifestyle help the obese women to perform and continue exercise. This program could be used in the community such as public health center for weight care and mental health promotion of middle-aged obese women.

• Journal of Nutrition and Health
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• v.35 no.1
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• pp.12-23
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• 2002

Gender differences in the effects of gonadectomy and high cholesterol diet on body weight and body cholesterol were investigated by using Sprague Dawley rats. Body weight, plasma and liver levels of cholesterol and triglyceride and platelet aggregation were examined in ovariectomized(OVX) or orchidectomized(ODX) rats with their intacts after feeding diet with or without 0.5% cholesterol. Body weight was significantly increased(p < 0.01) in OVX rats and significantly decreased(p < 0.01) in ODX rats compared to their respective intact rats, and cholesterol diet significantly(p < 0.05) decreased body weight in gonadectomized rats. Liver lobes from rats fed cholesterol diet were opaque and larger than those from rats find control dict, resulting in a significant increase(p < 0.01) in LW/BW ratio. Plasma and liver levels of total cholesterol were significantly increased (p < 0.01) in female rats regardless ovariectomy when find 0.5% cholesterol diet, but those levels in male rats were increased only when they were orchidectomized(p < 0.0l). Plasma HDL-cholesterol was significantly decreased(p < 0.05) in both sexes when find cholesterol diet. HDL-cholesterol were higher in female than male rats regardless treatments(p < 0.05). Liver triglyceride was significantly increased(p < 0.05) in both sexes when find cholesterol dict. Plasma level of triglyceride was not different among groups except significant decrease(p < 0.05) in cholesterol find ODX rats. Maximum platelet aggregation in female rats was significantly lower(p < 0.05) than male, but ovariectomy and cholesterol diet caused an increase te the level of male rats. Microscopic examination showed cholesterol diet caused a lipid accumulation in liver. Results indicate that intact female rats have higher response to hypercholestcrolemic diet than intact male rats and orchidectomy causes male rats more responsive to hypercholesterolemic diet. However, ovariectomy causes an increase female food efficiency ratio to the level of male rats, significantly increasing body weight.