Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effect of Rhus chinensis Gall Extract on Liver Function, Plasma Lipid Composition and Antioxidant System in Rats with High Fat Diet

오배자 추출물이 고지방식이를 급여한 흰쥐의 간기능, 혈청지질구성 및 항산화계에 미치는 영향

  • Choi, Moo-Young (Dept. of Food Science and Nutrition, Sangji University) ;
  • Choi, Eun-Jung (Dept. of Food Science and Nutrition, Sangji University) ;
  • Lee, Eun (Dept. of Animal Nutrition and Bio-resources, Sangji University)
  • 최무영 (상지대학교 식품영양학과) ;
  • 최은정 (상지대학교 식품영양학과) ;
  • 이은 (상지대학교 동물영양자원학과)
  • Published : 1999.06.01
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Abstract

The purposes of this study is to investigate the effect of Rhus chinensis gall extract on liver function, plasma lipid composition and antioxidant system in the obese rats with high fat diet for seven weeks. Thirty two male rats of Sprague Dawely strain were divided into four groups. they are normal group (basal diet), control group(high fat diet), III group(high fat diet with Rhus chinensis gall extract 25mg/kg body weight per day) and IV group(high fat diet with Rhus chinensis gall extract 250mg/kg body weight per day). Rats in III group and IV group were administered with Rhus chinensis gall extract accordingly. Weight gains showed a tendency to decrease in rat with Rhus chinensis gall extract group but showed no differences among treatment groups. Food intake and Food efficiency ratio were not significantly different among treatment groups. Plasma total cholesterol showed a tendency to decrease in Rhus chinensis gall extract group. HDL cholesterol showed a tendency to decrease in 25mg/kg of Rhus chinensis gall extract group. However, in the 250mg/kg of Rhus chinensis gall extract group, these values showed no significant difference compared to the control group (p<0.05). GPT activities showed no significant difference among treatment groups. GOT activities showed a tendency to decrease in the groups of Rhus chinensis gall extract groups. Lipid peroxide level was significantly higher in control group than those of normal group. In Rhus chinensis gall extract groups, lipid peroxide level showed a tendency to decrease, but glutathione peroxidase activity was progressively increased. Results of our research in this paper show that Rhus chinensis gall extract might improve liver function, antioxidant system and plasma lipid composition in rats with high fat diet.

Keywords

References

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