• Journal of Acupuncture Research
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• v.22 no.6
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• pp.111-123
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• 2005

Objectives : Neurological disorders have been one of main therapeutic targets of acupuncture. The present study investigated the protective effects of Gwakhyangjeonggisan herbal acupuncture solution (GHAS). Methods : We performed 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in glioblastoma cells, and did microarray analysis with cells exposed to reactive oxigen species (ROS) of hydrogen peroxide by 8.0 k Human cDNA, with cut-off level of 2-fold changes in gene expression. Results : MTT assay showed protective effect of GHAS on the glioblastoma cells exposed to hydrogen peroxide. When glioblastoma cells were exposed to hydrogen peroxide, 16 genes were upregulated. When the cells were pretreated with GHAS before exposure to hydrogen peroxide, 22 genes were upregulated. Most of the genes upregulated by hydrogen peroxide stimulation were reversed to downregulation by GHAS. Conclusion : The gene expression changes observed in the present study are supposed to be related to the protective molecular mechanism of GHAS in the glioblastoma cells exposed to ROS stress.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.293-297
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• 2013

Background: : Chemotherapy-induced thrombocytopenia (CIT) is an important cause of morbitity in patients with cancer. Aim: To investigate the effect of the baseline plasma D-dimer level, an important marker for thrombotic activity, on chemotherapy-induced thrombocytopenia in patients with stage III colon cancer. Materials and Methods: A total of 43 (28 men) eligible patients were divided into two groups according to whether they exhibited chemotherapy-induced thrombocytopenia: Group 1 (n=21) and Group 2 (n=22). Comparison was made using demographic, histopathologic, and laboratory variables. Additionally, baseline plasma D-dimer levels underwent receiver operation characteristics curve analysis, and areas under the curve were calculated. Sensitivity, specificity, and positive and negative likelihood rates were then determined. Results: The incidence of chemotherapy-induced thrombocytopenia had a significant correlation with baseline platelet count (r=0.568, P=0.031) and baseline plasma D-dimer levels (r=0.617, P=0.036). When the cut-off point for the latter was set as 498 ng/mL, the area under the curve was 0.89 (95%CI: 0.74-0.93), the sensitivity was 91.4%, the specificity was 89.7%, the positive likelihood rate was 3.64 and the negative likelihood rate was 0.24 for chemotherapy-induced thrombocytopenia diagnosis. Conclusions: The baseline level of plasma D-dimer could help to differentiate high-risk patients for chemotherapy-induced thrombocytopenia.

• Particle and aerosol research
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• v.14 no.3
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• pp.73-80
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• 2018

Recently, there has been much research on the effect of ultrafine dust on human body with increasing interest in the ultrafine dust. In the Republic of Korea, there are many old thermal power plants, and the amount of ultrafine dust emitted from the thermal power plants is reported to be about 14% of the total amount of domestic fine dust. Therefore, the amount of fine dust from the flue gas desulfurization facility in the thermal power plant needs be reduced. In this study, we made an experimental setup to simulate a flue gas desulfurization facility and analyzed the physical characteristics of the particles passing through a mist eliminator. Experiments were carried out to investigate the collection efficiency of the mist eliminator by using the Arizona Test Dust in a dry environment, and then spraying limestone slurry into the flue gas desulfurization system equipped with the mist eliminator to examine the size and morphology of limestone particles upstream and downstream of the mist eliminator. Cut-off size of the mist eliminator was formed at about $6{\mu}m$. The result of this study is expected to be helpful for designing an electrostatic precipitator for removing particles passing through the mist eliminator.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.2 s.332
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• pp.9-14
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• 2005

This paper reports the hot carrier induced RF performance degradation of bulk dynamic threshold voltage MOSFET (B-DTMOS) compared with bulk MOSFET (B-MOS). In the normal and moderate mode operations, the degradations of cut-off frequency $(f_{T})$ and minimum noise figure $(F_{min})$ of B-DTMOS are less significant than those of B-MOS devices. Our experimental results show that the RF performance degradation is more significant than the U performance degradation after hot carrier stressing. Also, the degradation characteristics of RF power Performance of B-DTMOS due to hot carrier effects are measured for the first time.

• JSTS:Journal of Semiconductor Technology and Science
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• v.5 no.2
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• pp.113-119
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• 2005

4H-SiC planar MESFETs were fabricated using ion-implantation on semi-insulating substrate without recess gate etching. A modified RCA method was used to clean the substrate before each procedure. A thin, thermal oxide layer was grown to passivate the surface and then a thick field oxide was deposited by CVD. The fabricated MESFET showed good contact properties and DC/RF performances. The maximum oscillation frequency of 34 GHz and the cut-off frequency of 9.3 GHz were obtained. The power gain was 10.1 dB and the output power of 1.4 W was obtained for 1 mm-gate length device at 2 GHz. The fabricated MESFETs showed the charge trapping-free characteristics and were characterized by the extracted small-signal equivalent circuit parameters.

• Journal of KSNVE
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• v.6 no.4
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• pp.503-511
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• 1996

There is a tendency of using the resilient mounting system to control the structure born noise transimitted from a engine of which weight is comparatively light and of which speed is comparatively high. According to recent reports, the resilient mounting system is applied to control the vibration of a engine running up to 300 - 400 R.P.M.. Furthermore, the resilient system is also used to the ships such as marine exploring ships, fishing boats, and military vessels. It is not desirous to apply the results for the resilient mounting systems of automobile engines to the controls of the vibrations of marine engines. Marine engines are worked under the idle speed in port and are operated up to the maximum contineous revolution at sea(running up condition). And marine engines are usually worked in inevitable conditions such as a misfire and a cut-off cylinder operating condition. Concerning the above running conditions, a resilient mounting system should be designed in the case of marine engines. In this paper, we studied the effect of engine's misfire on the resilient mounting systems. And the influences of design parameters, such as dynamic characteristics and fitting angles of resilient rubber mountings, were also investigated respectively on the single and double resilient mounting systems.

• Lingua Humanitatis
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• v.6
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• pp.295-320
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• 2004

$\ulcorner$Xixiangji[West chamber]$\lrcorner$ is one of the most popular Chinese dramas which was first translated into Korean by Chung-hee Kim in 1811. $\ulcorner$Dongsanggi[East chamber]$\lrcorner$is a Korean drama which was written in Chinese by Ok Lee in 1791. It adopted the form of Chinese traditional drama, $\ulcorner$xixianji$\lrcorner$. 1 think theses are very interesting examples which show how we accepted Chinese dramas through translation or modification and created our own dramas in the past. 1 quoted their names in the title because it is thought that they can represent the direction of the stream of cultural exchange between two countries in the past. The direction has recently changed. Han stream[Korean cultural effect] has become very powerful in whole Asia in last 10 years. Cultural exchange between Korea and China has been very steady and popular over 2000 years before the 20th century We used to have cultural identity by using Chinese character and accept many of the cultural aspects from China. Now, we are trying to reestablish the relationship which has been cut off for about 50years. In this paper I tried to retrospect the results of cultural exchange in the past and argue about the problems we are now facing by examining interchange or acceptance of the Chinese drama including translations and theatrical performances. 1 also tried to suggest the diverse ways of mutual exchange to uplift the cultural level of two countries.

• Journal of architectural history
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• v.21 no.6
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• pp.63-76
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• 2012

Modern railway construction by Japanese had a great influence on the urbanization, transformation of urban structure and landscape during the Japanese imperialism and compressive increasing period in Iri(Iksan). This paper aims to find out the effect of railway on the modern urban structure and urban landscape in Iri(Iksan). Railways in Iri, Honam railway, Kunsan railway, Jeonla railway have been constructed progressively during 1911 and 1915 with Iri and old Iri(east-Iri) station. From the analysis of land registration maps and street plans, old photographies and historical records, some significant features underling railway construction can be followed in view of modern urbanization process in Iri. Firstly railways cut off the possibility of developing urban structure based on traditional spatial structure of Iksan. Secondly railways made dual spatial structure in Iri. Japanese and Korean life zone were divided into separate district around urbanization area and market place. Thirdly traditional space cognition system based on four cardinal directions were changed to front and rear space of railway station. Fourthly railways and stations caused neo-baroque spatial order and imperialistic urban landscape of Iri with axis, vista and gridiron plan. Fifthly break points and fringe belts garbling modern urbanization process are created. Sixthly modern cultural and consumptive urban spaces were taken their seats in relation with daily urban life.

• Journal of Oral Medicine and Pain
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• v.39 no.3
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• pp.100-106
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• 2014

Purpose: This study was performed to investigate the relationship between temporomandibular disorders (TMDs) and the asymmetry of the mandibular height. Methods: We compared 100 randomly selected TMD patients diagnosed by the research diagnostic criteria for TMD (RDC/TMD) Axis I with 100 non-TMD control subjects matched with the TMD patients in age and gender. The mandibular heights were measured on an orthopantomogram and the asymmetry index (AI) was calculated as previously described. Results: The absolute AI value of 4.37% turned out to be the least cut-off value defining asymmetry, which showed a significant difference in asymmetry incidence (p<0.01) between the TMD and control groups. The risk of TMD increased in the asymmetry group by 4.57 (odds ratio). The incidence of asymmetry was not related to age and gender in both of the TMD and control groups. When dividing the TMD group according to the RDC/TMD Axis I diagnosis, neither the incidence of muscle disorder nor disk displacement was related to the incidence of asymmetry. However, a higher incidence of asymmetry was observed in the subjects classified into the arthrosis/arthritis groups (p<0.01). Conclusions: Although it does not imply a direct cause-and-effect relationship, asymmetry resulting in more than 4.37% difference between mandibular heights may increase the risk of TMD and correlates positively to the incidence of arthritic change in the temporomandibular joint of TMD patients.

• Land and Housing Review
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• v.8 no.4
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• pp.267-274
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• 2017

Since LID design process for the urban regeneration has not yet been established in Korea, this study was extablished in LID design process through reterauture reviews and expert opinions. But the extablished LID design processes have many limitations to be applied to proper LID facilities to the site because of not considering characteristics and water flow of the site. To solve the limitations of existing design processes, it is necessary for analysis of water flow through GIS analysis at the site. After analysis of water flow, it is important to find areas cut off water flow and to install LID facilities at those points. Through these considerations, this study present the improved LID design process to apply to urban regeneration.