• 한국안전학회지
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• 제25권6호
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• pp.180-185
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• 2010

We have to develop more correct and systematic way to choose Hazardous Highway Segments. In this research, we applied CRP(Continuous Risk Profile) technique which developed by UC Berkeley Traffic Safety Center in year of 2007, and can analyze yearly dangerous level tendency of continuity in the route of main road that is under California Department of Transportation(Caltrans). We changed standard of CRP to suit in Korean circumstance with consideration in radius of curve and traffic volume. For the verification by actual accident data, we embodiment the CRP by using the data from total of 587 case of accident in latest 10 years in Gyeong-Bu Highways, the amount of 56km. Finally, the effectiveness of technique in this research has been verified by obtained same result with current method for Hazardous Highway Segments. In addition, when calculating the Hazardous Highway Segments with technique that presented in this research we obtained following statements. First, identified dangerous level of continuity in the route by using CRP. Second, Accurate of Actual Hazardous Highway Segments selection has been developed by using last 10 year's data and profile making which provide simplicity analyze of Tendency. Third, after reforming the way of selection, effective range has been wider than former selection and it gives advantage for the policy side.

• Investigative Magnetic Resonance Imaging
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• 제23권1호
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• pp.34-37
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• 2019

Gadolinium contrast agents (CAs) are integral components of clinical magnetic resonance imaging (MRI). However, safety concerns have arisen regarding the use of gadolinium CAs, due to their association with nephrogenic systemic fibrosis (NSF). Furthermore, recently the long-term retention of $Gd^{3+}-based$ CAs in brains patients with normal renal function raised another possible safety issue. The safety concerns of $Gd^{3+}-based$ CAs have been based on the ligand structure of $Gd^{3+}-based$ CAs, and findings that $Gd^{3+}-based$ CAs with linear ligand structures showed much higher incidences of NSF and brain retention of CAs than $Gd^{3+}-based$ CAs with macrocyclic ligand structure. In the current study, we report the in vivo biodistribution profile of a new highly stable multifunctional $Gd^{3+}-based$ CA, with macrocyclic ligand structure (HNP-2006). MR imaging using HNP-2006 demonstrated a significant contrast enhancement in many different organs. Furthermore, the contrast enhanced tumor imaging using HNP-2006 confirmed that this new macrocyclic CA can be used for detecting tumor in the central nervous system. Therefore, this new multifunctional HNP-2006 with macrocyclic ligand structure shows great promise for whole-body clinical application.

• Asian Journal of Innovation and Policy
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• 제9권3호
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• pp.308-338
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• 2020

The entrepreneurial journey is not short of challenges, and about 90% + tech start-ups experience failure (Startup Genome, 2019). The magnitude of the challenges varies across the tech start-up lifecycle stages, namely emergence, stability, and growth. This opens the research question, do the profiles of a start-up and its co-founder impact start-up success or failure across its lifecycle stages? This study aims to understand and identify the profiles of tech start-ups and their co-founders. We gathered primary data from 151 start-ups (Status: 101 failed and 50 successful ones), and they are across different lifecycle stages and represent six major start-up hubs in India. The chi-square test on status and start-up's lifecycle stage indicates a noticeable correlation, and they are not independent. The Kruskal Wallis test was used to distinguish statistically significant profile attributes. The parameters distinguishing success and failure are identified, and the need to deliver customer experience is emphasized by the start-up profile attributes: Product/service, high-tech nature of a start-up, investor fund availed, co-founder experience, and employee count. The importance of entrepreneurial experience is ascertained with entrepreneur profile attributes: Entrepreneurial expertise, the number of prior and current start-ups, their willingness to start again in the event of failure, and age of co-founder, which is a proxy to learning and experience. This study has implications for entrepreneurs, investors, and policymakers.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제18권5호
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• pp.1341-1368
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• 2024

The concept of privacy-preserving collaborative filtering (PPCF) has been gaining significant attention. Due to the fact that model-based recommendation methods with privacy are more efficient online, privacy-preserving memory-based scheme should be avoided in favor of model-based recommendation methods with privacy. Several studies in the current literature have examined ant colony clustering algorithms that are based on non-privacy collaborative filtering schemes. Nevertheless, the literature does not contain any studies that consider privacy in the context of ant colony clustering-based CF schema. This study employed the ant colony clustering model-based PPCF scheme. Attacks like shilling or profile injection could potentially be successful against privacy-preserving model-based collaborative filtering techniques. Afterwards, the scheme's robustness was assessed by conducting a shilling attack using six different attack models. We utilize masked data-based profile injection attacks against a privacy-preserving ant colony clustering-based prediction algorithm. Subsequently, we conduct extensive experiments utilizing authentic data to assess its robustness against profile injection attacks. In addition, we evaluate the resilience of the ant colony clustering model-based PPCF against shilling attacks by comparing it to established PPCF memory and model-based prediction techniques. The empirical findings indicate that push attack models exerted a substantial influence on the predictions, whereas nuke attack models demonstrated limited efficacy.

• 센서학회지
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• 제29권5호
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• pp.283-292
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• 2020

Current sensors that use a Hall element and Hall IC to measure the magnetic fields generated in steel silicon core gaps do not distinguish between direct and alternating currents. Thus, they are primarily used to measure direct current (DC) in industrial equipment. Although such sensors can measure the DC when installed in expensive equipment, ascertaining problems becomes difficult if the equipment is set up in an unexposed space. The control box is only opened during scheduled maintenance or when anomalies occur. Therefore, in this paper, a method is proposed for facilitating the safety management and maintenance of equipment when necessary, instead of waiting for anomalies or scheduled maintenance. A Bluetooth 4.0 low-energy current-sensor system based on near-field communication is used, which compensates for the nonlinearity of the current-sensor output signal using a piecewise linear model. The sensor is controlled using its generic attribute profile. Sensor nodes and cell phones used to check the signals obtained from the sensor at 50-A input currents showed an accuracy of ±1%, exhibiting linearity in all communications within the range of 0 to 50 A, with a stable output voltage for each communication segment.

• Journal of Pharmaceutical Investigation
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• 제37권3호
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• pp.159-166
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• 2007

In order to develop an optimum formulation for iontophoretic delivery of vitamine C-2-phosphate (VCP) from Carbopol hydrogel, we have investigated various factors which can affect the iontophoretic flux through skin. Such factors as drug concentration, current density, current profile, current duration, ionic strength, pH and percutaneous enhancers (ethanol, glycerine, propylene glycerol, sorbitol, urea) were studied. Compared to the flux by passive or anodal delivery, the flux by cathodal delivery increased markedly, and thus, only cathodal delivery was used in the rest of the flux experiments. Flux increased linearly as the drug concentration and current density increased. As the duration of current application increased from 30 min to 120 min, flux increased linearly, however the AUC was not directly proportional to the applied amount of current. Flux also increased as the pH increased, possibly due to the increase in ionization of phosphate group. As the ionic strength increased, flux decreased. No significant increase in flux was observed after enhancer application, indicating that the effect of current on flux is dominating over the effect of percutaneous enhancers (P>0.05). These results provide important informations that are needed for optimal formulation of iontophortic delivery for VCP.

• Journal of Power Electronics
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• 제10권3호
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• pp.285-292
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• 2010

This paper presents a current mode integrated control technique (CM-ICT) using a modified voltage space vector modulation (MSVM) for Z-source inverter (ZSI) fed induction motor drives. MSVM provides a better DC voltage boost in the dc-link, a wide range of AC output voltage controllability and a better line harmonic profile. In a voltage mode ICT (VM-ICT), the outer voltage feedback loop alone is designed and it enforces the desired line voltage to the motor drive. An integrated control technique (ICT), with an inner current feedback loop is proposed in this paper for the purpose of line current limiting and soft operation of the drive. The current command generated by the PI controller and limiter in the outer voltage feedback loop, is compared with the actual line current, and the error is processed through the PI controller and a limiter. This limiter ensures that, the voltage control signal to the Z-source inverter is constrained to a safe level. The rise and fall of the control signal voltage are made to be gradual, so as to protect the induction motor drive and the Z-source inverter from transients. The single stage controller arrangement of the proposed CM-ICT offers easier compensation. Analysis, Matlab/Simulink simulations, and experimental results have been presented to validate the proposed technique.

• Journal of Pharmaceutical Investigation
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• 제31권4호
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• pp.273-279
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• 2001

The purpose of this study is to characterize the iontophoretic transport of growth hormone releasing peptides (GHRP-6) through hairless mouse skin from aqueous solution. The effect of various factors, such as pH, poloarity, current profile, current density, current duration, ionic strength, drug concentration, and enhancer application was studied to obtain basic knowledge on the transport. We have also studied the stability of GHRP-6 in solution with/without current. The donor chamber was filled with phosphate buffer solution containing GHRP-6 and the receptor chamber was filled with phosphate buffer solution (pH 7.4). Ag/AgCl electrode was used for their stability and reversibility. At a predetermined time interval, sampling was made and the concentration of drug was analysed using HPLC system. The results showed that, compared to passive flux, the total amount of drug transported increased markedly by the application of anodal current. Cathodal flux was similar to passive flux. Flux increased with the current density, the duration of current application and drug concentration. The effect of enhancers on the flux was studied using hydrophilic (5% N-methyl pyrrolidone) and hydrophobic (5% propylene glycol monolaurate, 5% oleic acid) enhancers. Application of enhancer also increased the flux.

• Korean Chemical Engineering Research
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• 제54권1호
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• pp.108-113
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• 2016

A miniaturized lab-scale Cu plating cell for the metallization of electronic devices was fabricated and its deposit uniformity and profile were investigated. The plating cell was composed of a polypropylene bath, an electrolyte ejection nozzle which is connected to a circulation pump. In deposit uniformity evaluation, thicker deposit was found on the bottom and sides of substrate, indicating the spatial variation of deposit thickness was governed by the tertiary current distribution which is related to $Cu^{2+}$ transport. The surface morphology of Cu deposit inside photo-resist pattern was controlled by organic additives in the electrolyte as it led to the flatter top surface compared to convex surface which was observed in the deposit grown without organic additives.

• 전기전자학회논문지
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• 제15권2호
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• pp.129-133
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• 2011

A spread spectrum clock generation is an efficient way to reduce electro-magnetic interference (EMI) radiation in modern mixed signal chip systems. The proposed circuit generates the spread spectrum clock by directly injecting the modulation voltage into the voltage-controlled oscillator (VCO) current source for SATA II. The resulting 33KHz modulation profile has a Hersey-Kiss shape with a rounded peak. The chip has been fabricated using $0.18{\mu}m$ CMOS process and test results show that the proposed circuit achieves 0.509% (5090ppm) down spreading at 1.5GHz and peak power reduction of 10dB. The active chip area is 0.36mm ${\times}$ 0.49mm and the chip consumes 30mW power at 1.5GHz.